Compound Summary
Compound Information
药名: | isorhynchophylline |
分子式: | C22H28N2O4 |
Smiles: | CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=CC=CC=C4NC3=O |
成分: | HBIN031192;HBIN013301;HBIN031193 |
OB_score: | 47.30859 |
CAS_id: | 1811243 |
SymMap_id: | SMIT09770;SMIT01466;SMIT02495;SMIT02502;SMIT19288;SMIT09758 |
TCMID_id: | 11676;11677;31377 |
TCMSP_id: | MOL008486;MOL008471 |
PubChem_id: | 3037048 |
化合物对应的植物
| 植物ID | 拉丁名 | 药用植物名 | 药名 | 来源 | 功能与主治 | 使用民族 |
|---|
| TCMBANKHE000418 | Uncaria africana | 非洲钩藤 | ||||
| TCMBANKHE000715 | Uncaria guianensis | 圭亚那钩藤 | ||||
| TCMBANKHE001023 | Uncaria cordata | 新型钩藤 | ||||
| TCMBANKHE001591 | Uncaria attenuata | 夏钩藤 | ||||
| TCMBANKHE001922 | Uncaria acida | 酸勾藤 | ||||
| TCMBANKHE001992 | 钩藤根 | |||||
| TCMBANKHE002742 | Uncaria callophylla | 后夜钩藤 | ||||
| TCMBANKHE002816 | Uncaria longiflora | 长话钩藤 | ||||
| TCMBANKHE002833 | Uncaria tomentosa | 秘鲁钩藤 | ||||
| TCMBANKHE004268 | Uncaria borneensis | 婆罗洲钩藤 | ||||
| TCMBANKHE004610 | Ramulus Uncariae cum Uncis | 钩藤 | To remove heat, subdue hyperactivity of the liver, and arrest convulsions./Infant fright wind and night crying, exuberant heat stirring wind, epilepsy of pregnancy, liver yang dizziness, liver fire headache. | |||
| TCMBANKHE007721 | Exocarpium Benincasae | 冬瓜皮 | 1. To promote diuresis to relieve edema. 2. To clear summer-heat./Edema, inhibited urination [=dysuria], diarrhea, swelling of sores. | |||
| TCMBANKHE007767 | Semen Cavaliae | 刀豆 | To warm the stomach and check its upward adverse movement./Vacuity cold and hiccough, vomiting. | |||
| TCMBANKHE007978 | Uncaria sinensis | 华钩藤 | See Uncaria rhynchophylla./See Uncaria rhynchophylla. | |||
| TCMBANKHE006958 | Papaver commutatum [Syn. Papaver rhoeas ] | 丽春花 | To suppress cough, settle pain, check diarrhea./Cough, migraine, abdominal pain, dysentery. | |||
| TCMBANKHE007551 | Catechu | 儿茶 | To reduce toxic and to remove dampness./To arrest exudation, promote the growth of new tissue, and cure wounds. | |||
| TCMBANKHE008750 | Uncaria elliptica | 椭圆钩藤 | ||||
| TCMBANKHE007889 | 杜仲叶 | Lumbar and back pain, limp aching inability of legs and knees, hypertension. | ||||
| TCMBANKHE006899/YNS-5/YEM-284/XU-215 | Uncaria sessilifructus [Syn. Nauclea sessilifructus ]|Uncaria sessilifructus Roxb.|Uncaria sessilifructus | 白钩藤 | 白钩藤 | 云南药材标准：第三册|云南民族药物志：第二卷|广西省来宾市金秀县六段村永新村 | 清火解毒，消肿止痛，除风通血。用于风湿病肢体关节红肿热痛或酸痛重着；风火气血不和所致的头目胀痛。 | 彝族 |
| TCMBANKHE008324/YEM-443 | Uncaria macrophylla|Uncaria macrophylla Wall. | 大叶钩藤 | 大叶钩藤 | 云南民族药物志：第三卷 | See Uncaria rhynchophylla./See Uncaria rhynchophylla. | 傣族/苗族/佤族/彝族/藏族/壮族 |
植物对应的疾病
| 疾病ID | 病名 | 疾病类型 | MeSH | 参考文献 |
|---|
| TCMBANKDI000019 | Parkinson Disease | disease | Nervous System Diseases | 22113202 |
化合物对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE000121 | KCNH2 | ERG-1; ERG1; H-ERG; HERG; HERG1; Kv11.1; LQT2; SQT1 | potassium voltage-gated channel subfamily H member 2 |
| TCMBANKGE000201 | ESR1 | ER; ESR; ESRA; ESTRR; Era; NR3A1 | estrogen receptor 1 |
| TCMBANKGE000205 | NOS2 | HEP-NOS; INOS; NOS; NOS2A | nitric oxide synthase 2 |
| TCMBANKGE000212 | GRIN1 | GluN1; MRD8; NDHMSD; NDHMSR; NMD-R1; NMDA1; NMDAR1; NR1 | glutamate ionotropic receptor NMDA type subunit 1 |
| TCMBANKGE000286 | GSK3B | - | glycogen synthase kinase 3 beta |
| TCMBANKGE000309 | SCN5A | CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 | sodium voltage-gated channel alpha subunit 5 |
| TCMBANKGE000701 | ESR2 | ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 | estrogen receptor 2 |
| TCMBANKGE000766 | ACHE | ACEE; ARACHE; N-ACHE; YT | acetylcholinesterase (Cartwright blood group) |
| TCMBANKGE000813 | DPP4 | ADABP; ADCP2; CD26; DPPIV; TP103 | dipeptidyl peptidase 4 |
| TCMBANKGE000869 | DRD2 | D2DR; D2R | dopamine receptor D2 |
| TCMBANKGE000903 | PTGS1 | COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS | prostaglandin-endoperoxide synthase 1 |
| TCMBANKGE000938 | CDK2 | CDKN2; p33(CDK2) | cyclin dependent kinase 2 |
| TCMBANKGE001073 | PTGS2 | COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 | prostaglandin-endoperoxide synthase 2 |
| TCMBANKGE001506 | ADRA1B | ADRA1; ALPHA1BAR | adrenoceptor alpha 1B |
| TCMBANKGE004266 | AR | AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM | androgen receptor |
| TCMBANKGE005535 | CHRM1 | HM1; M1; M1R | cholinergic receptor muscarinic 1 |
| TCMBANKGE005653 | GRIN2A | EPND; FESD; GluN2A; LKS; NMDAR2A; NR2A | glutamate ionotropic receptor NMDA type subunit 2A |
| TCMBANKGE006466 | GRIN2D | EB11; EIEE46; GluN2D; NMDAR2D; NR2D | glutamate ionotropic receptor NMDA type subunit 2D |
| TCMBANKGE006477 | GRIN3B | GluN3B; NR3B | glutamate ionotropic receptor NMDA type subunit 3B |
| TCMBANKGE006943 | CHRM3 | EGBRS; HM3; PBS | cholinergic receptor muscarinic 3 |
| TCMBANKGE008011 | HTR2A | 5-HT2A; HTR2 | 5-hydroxytryptamine receptor 2A |
| TCMBANKGE008163 | GRIN3A | GluN3A; NMDAR-L; NMDAR3A; NR3A | glutamate ionotropic receptor NMDA type subunit 3A |
| TCMBANKGE008702 | OPRM1 | LMOR; M-OR-1; MOP; MOR; MOR1; OPRM | opioid receptor mu 1 |
| TCMBANKGE009455 | CHRM5 | HM5 | cholinergic receptor muscarinic 5 |
| TCMBANKGE011079 | PRSS1 | TRP1; TRY1; TRY4; TRYP1 | serine protease 1 |
| TCMBANKGE011923 | CHRM4 | HM4; M4R | cholinergic receptor muscarinic 4 |
| TCMBANKGE013361 | GRIN2C | GluN2C; NMDAR2C; NR2C | glutamate ionotropic receptor NMDA type subunit 2C |
| TCMBANKGE014625 | OPRD1 | DOP; DOR; DOR1; OPRD | opioid receptor delta 1 |
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Dai SX Lab