Compound Summary


  Compound Information

药名:

7-hydroxy-3-butylidene-phthalide

分子式:

C12H12O3

Smiles:

CCCC=C1C2=C(C(=CC=C2)O)C(=O)O1

成分:

HBIN013228;HBIN008359;HBIN008360;HBIN043725

OB_score:

43.176755

CAS_id:

93236-67-0

SymMap_id:

SMIT19244;SMIT14534;SMIT04402;SMIT12636;SMIT17664

TCMID_id:

31161;2796;30694;19717

TCMSP_id:

MOL011784;MOL002098

PubChem_id:

5281559


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE006054 Radix chuanxiong;Rhizoma Chuanxiong 川芎 1. To invigorate blood and promote qi circulation; 2. To expel wind and stop pain/Cerebral ischemia, postpartum pain, acute icterohepatitis, menstrual disorder, amenorrhea and dysmenorrhea, concretion and conglomeration, chest and rib-side stabbing pain, painful swelling from knocks and falls, headache, wind-damp impediment pain.
TCMBANKHE003063 Herba Plantaginis 车前草 To remove heat and to induce diureses, to promote expectoration, to reduce heat in blood and to counteract toxicity./Treatment of edema with oliguria, urinary infection with difficult painful urination, diarrhea caused by summer-damp, cough caused by phlegm-heat, spitting of blood, epistaxis, carbuncles and sores.
TCMBANKHE004258 Radix Angelicae sinensis 当归根 To enrich blood, activate blood circulation, regulate menstruation, relieve pain, and relax bowels./Women’s diseases, blood deficiency syndrome, menstrual disorder, amenorrhea and dysmenorrhea, dysmenorrhea due to anemia, thrombophlebitis, neuralgia, arthritis, chronic nephritis, constrictive aortitis, blood vaculty, pernicious anemia, anemia due to folic acid deficiency, dysentery, hepatitis, Raynaud’s disease, lumbago, various pains due to blood stasis and rheumatic impediment, sores, welling abscess, constipation, ulcer in gastrointestinal tract, skin diseases, eczema, dermatitis, neurodermatitis, psoriasis.
TCMBANKHE007292 藁本 Headache due to externally contracted wind-cold, vertex headache, pain in tooth and cheek, migraine, wind-cold-damp impediment, pain in limbs.
TCMBANKHE008104 Radix chuanxiong;Rhizoma Chuanxiong 川芎 1. To invigorate blood and promote qi circulation; 2. To expel wind and stop pain/Cerebral ischemia, postpartum pain, acute icterohepatitis, menstrual disorder, amenorrhea and dysmenorrhea, concretion and conglomeration, chest and rib-side stabbing pain, painful swelling from knocks and falls, headache, wind-damp impediment pain.
TCMBANKHE005228/YEM-235 Cortex Magnoliae officilis;Magnolia officinalis|Magnolia officinalis Rehd.et Wils. 厚朴 厚朴 云南民族药物志:第二卷 To eliminate damp and relieve distension;To dry damp and disperse phlegm, precipitate qi and eliminate fullness, lower blood pressure./1. Broad-spectrum antibacterial.2. Magnocurarine, one of the active components, can relaxstriated muscles.3. Its decoction stimulates the smooth muscles of intestines and bronchii in rabbits in vitro.4. Magnocuraine may also lower blood pressure and accelerate heart rate.5.Amebic dysentery, vomiting and diarrhea, food accumulation and qi stagnation, abdominal distention and constipation, phlegm-rheum cough asthma. 彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000633 ADRB2 ADRB2R; ADRBR; B2AR; BAR; BETA2AR adrenoceptor beta 2
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001755 MAOB - monoamine oxidase B
TCMBANKGE003157 CHRM2 HM2 cholinergic receptor muscarinic 2
TCMBANKGE003625 SLC6A4 5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT solute carrier family 6 member 4
TCMBANKGE005535 CHRM1 HM1; M1; M1R cholinergic receptor muscarinic 1
TCMBANKGE008124 ADRA2B ADRA2L1; ADRA2RL1; ADRARL1; ALPHA2BAR; FAME2; alpha-2BAR adrenoceptor alpha 2B
TCMBANKGE009256 SLC6A2 NAT1; NET; NET1; SLC6A5 solute carrier family 6 member 2
TCMBANKGE014050 GABRA1 ECA4; EIEE19; EJM; EJM5 gamma-aminobutyric acid type A receptor subunit alpha1
TCMBANKGE014941 DPEP1 MBD1; MDP; RDP dipeptidase 1