Compound Summary


  Compound Information

药名:

shogaol

分子式:

C17H24O3

Smiles:

CCCCCC=CC(=O)CCC1=CC(=C(C=C1)O)OC

成分:

HBIN043938; HBIN012818; HBIN046702

OB_score:

31.004162

CAS_id:

555-66-8

SymMap_id:

SMIT02382; SMIT00160

TCMID_id:

25014;19831

TCMSP_id:

MOL002495

PubChem_id:

5281794


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000767 Fructus Amomi Rotundus 豆蔻 To resolve damp, to remove stagnancy of food, and to promote digestion./Treatment of loss of appetite due to accumulation of turbid damp in the spleen and stomach, feeling of suffocation in the chest with anorexia at the early stage of damp-warm syndromes, nausea, vomiting, distension and pain in the chest and abdomen caused
TCMBANKHE000769 Lindera triloba
TCMBANKHE000777 姜叶
TCMBANKHE002817 生姜汁
TCMBANKHE006944 Caulis Erycibes 丁公藤 To dispel wind and deprive dampness, reduce swelling, relieve pain./Wind-damp impediment pain, hemiplegia, painful swelling from knocks and falls.
TCMBANKHE003725 Rhizoma Zingiberis Recens 生姜 To induce perspiration and dispel cold, to warm the stomach and arret vomiting, and to resolve phlegm and relieve cough./Wind-cold common cold, fever and aversion to wind, headache and nasal congestion, vomiting, phlegm-rheum cough asthma, distention fullness, diarrhea.
TCMBANKHE006934 Rhizoma Zingiberis 干姜 To dispel cold from the spleen and the stomach, to promote recovery from collapse, and to eliminate damp and phlegm./Cold pain in stomach duct and abdomen, vomiting, diarrhea, yang -collapse reversal flow, cold rheum asthma cough, cold-damp impediment pain.
TCMBANKHE007230 Rhizoma Pinelliae 半夏 To remove damp and phlegm, to relieve nausea and vomiting, and to eliminate stuffiness in the chest and the epigastrium./Cough and asthma with abundant phlegm, vomiting nausea, glomus in chest, dizziness, headache, vexation and agitation in night, goiters with phlegm node, swelling toxin of welling abscess and flat abscess.
TCMBANKHE006477 Zingiber aromaticum 芳香姜
TCMBANKHE005628/YEM-121 Fructus Chaenomelis|Chaenomeles speciosa (Sweet) Nakai 木瓜|皱皮木瓜 木瓜 云南民族药物志:第一卷 To lessen contracture, regulate stomach function, and dispel damp./Vomiting and diarrhea with cramp, wind-damp impediment pain, cough and abundant phlegm, diarrhea, dysentery, painful wound from knocks and falls, beriberi with edema. 傣族/景颇族/苗族/彝族/藏族
TCMBANKHE003577/YEM-245 Cortex Zingiberis|Zingiber officinale Rosc. 姜皮|姜 云南民族药物志:第二卷 阿昌族/布依族/傣族/德昂族/哈尼族/基诺族/景颇族/傈僳族/苗族/水族/佤族/瑶族/彝族/藏族/壮族
TCMBANKHE004023/YEM-391/XU-797 Fructus Ligustri lucidi|Ligustrum lucidum Ait.|Ligustrum lucidum 女贞子|女贞 女贞子 云南民族药物志:第二卷|云南省文山州麻栗坡县 To replenish the liver and kidney, improve eyesight and promote the growth of black hair.;Treament of vertigo, tinnitus, weakness in the loins and knees, premature whitening of hair and impaired eyesight due to deficiency of yin of the liver and kidney./Septicemia, chronic bronchitis, acute dysentery, dizziness and tinnitus, premature graying in beard and hair, dim vision.;1. Its component oleanolic acid can prevent and relieve cyclophosphamide-induced leukocytopenia in mice.2. Enhancing the anoxia tolerance of mice under atmospheric pressure.3. Increasing coronary flow in rabbits in vitro.4. Relaxing adrenaline-induced vasocontricyion in rabbits in vitro.5. Lowering the level of blood lipid. 阿昌族/德昂族/基诺族/景颇族/傈僳族/水族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献
TCMBANKDI000053 leukemia disease Neoplasms 24215632
TCMBANKDI000086 Colonic Neoplasms group Digestive System Diseases; Neoplasms 23612072

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000096 TBK1 FTDALS4; IIAE8; NAK; T2K TANK binding kinase 1
TCMBANKGE000196 FAS ALPS1A; APO-1; APT1; CD95; FAS1; FASTM; TNFRSF6 Fas cell surface death receptor
TCMBANKGE000223 KEAP1 INrf2; KLHL19 kelch like ECH associated protein 1
TCMBANKGE000330 HMOX1 HMOX1D; HO-1; HSP32; bK286B10 heme oxygenase 1
TCMBANKGE000734 GCLC GCL; GCS; GLCL; GLCLC glutamate-cysteine ligase catalytic subunit
TCMBANKGE000749 ALOX5 5-LO; 5-LOX; 5LPG; LOG5 arachidonate 5-lipoxygenase
TCMBANKGE000764 TRPV1 VR1 transient receptor potential cation channel subfamily V member 1
TCMBANKGE000792 FASLG ALPS1B; APT1LG1; APTL; CD178; CD95-L; CD95L; FASL; TNFSF6; TNLG1A Fas ligand
TCMBANKGE000820 CFLAR CASH; CASP8AP1; CLARP; Casper; FLAME; FLAME-1; FLAME1; FLIP; I-FLICE; MRIT; c-FLIP; c-FLIPL; c-FLIPR; c-FLIPS; cFLIP CASP8 and FADD like apoptosis regulator
TCMBANKGE000970 FASN FAS; OA-519; SDR27X1 fatty acid synthase
TCMBANKGE000978 GCLM GLCLR glutamate-cysteine ligase modifier subunit
TCMBANKGE001126 NFE2L2 HEBP1; IMDDHH; NRF2; Nrf-2 nuclear factor, erythroid 2 like 2
TCMBANKGE001131 CASP9 APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 caspase 9
TCMBANKGE001132 BAX BCL2L4 BCL2 associated X, apoptosis regulator
TCMBANKGE001156 CASP3 CPP32; CPP32B; SCA-1 caspase 3
TCMBANKGE001166 BCL2 Bcl-2; PPP1R50 BCL2 apoptosis regulator
TCMBANKGE001169 BCL2L1 BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 BCL2 like 1
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001205 DDIT3 AltDDIT3; C/EBPzeta; CEBPZ; CHOP; CHOP-10; CHOP10; GADD153 DNA damage inducible transcript 3
TCMBANKGE006834 FTL LFTD; NBIA3 ferritin light chain
TCMBANKGE009472 AKR1B10 AKR1B11; AKR1B12; ALDRLn; ARL-1; ARL1; HIS; HSI aldo-keto reductase family 1 member B10
TCMBANKGE010874 GGTLC1 GGTL6; GGTLA3; GGTLA4; dJ831C21.1; dJ831C21.2 gamma-glutamyltransferase light chain 1
TCMBANKGE011364 GDF15 GDF-15; MIC-1; MIC1; NAG-1; PDF; PLAB; PTGFB growth differentiation factor 15