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Compound Summary

Compound Information

药名:	phorbol 12-myristate 13-acetate
分子式:	C8H8HgO2
Smiles:	CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C
成分:	HBIN039602; HBIN039609; HBIN000982
SymMap_id:	SMIT17196
TCMID_id:	32011; 17173
PubChem_id:	27924

化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE000174		八角莲
TCMBANKHE005586	Fructus Crotonis;Croton macrostachys	巴豆	1. To drain accumulated cold downward; 2. To transform water and reduce edema; 3. To resolve phlegm and benefit throat/Distention fullness and sudden pain in chest and a bdomen, fecal stoppage, diarrhea and dysentery, edema and enlarged abdomen, phlegm-rheum asthma fullness, throat wind, throat impediment, concretion and conglomeration, welling abscess and flat abscess, malign sore and scab lichen.
TCMBANKHE008922	Koelreuteria paniculata	栾树	To clear liver and brighten eyes./Eye pain and tearing, red eyes with gall.

植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000051	IL1B	IL-1; IL1-BETA; IL1F2; IL1beta	interleukin 1 beta
TCMBANKGE000096	TBK1	FTDALS4; IIAE8; NAK; T2K	TANK binding kinase 1
TCMBANKGE000109	ACTB	BRWS1; PS1TP5BP1	actin beta
TCMBANKGE000138	PRKCE	PKCE; nPKC-epsilon	protein kinase C epsilon
TCMBANKGE000162	MMP13	CLG3; MANDP1; MDST; MMP-13	matrix metallopeptidase 13
TCMBANKGE000222	EDN1	ARCND3; ET1; HDLCQ7; PPET1; QME	endothelin 1
TCMBANKGE000256	PRKCA	AAG6; PKC-alpha; PKCA; PKCI+/-; PKCalpha; PRKACA	protein kinase C alpha
TCMBANKGE000258	EGR1	AT225; G0S30; KROX-24; NGFI-A; TIS8; ZIF-268; ZNF225	early growth response 1
TCMBANKGE000310	FOSB	AP-1; G0S3; GOS3; GOSB	FosB proto-oncogene, AP-1 transcription factor subunit
TCMBANKGE000316	IL5	EDF; IL-5; TRF	interleukin 5
TCMBANKGE000343	RPS6KA2	HU-2; MAPKAPK1C; RSK; RSK3; S6K-alpha; S6K-alpha2; p90-RSK3; p90RSK2; pp90RSK3	ribosomal protein S6 kinase A2
TCMBANKGE000368	PLAUR	CD87; U-PAR; UPAR; URKR	plasminogen activator, urokinase receptor
TCMBANKGE000433	IL37	FIL1; FIL1(ZETA); FIL1Z; IL-1F7; IL-1H; IL-1H4; IL-1RP1; IL-37; IL1F7; IL1H4; IL1RP1	interleukin 37
TCMBANKGE000445	CD44	CDW44; CSPG8; ECMR-III; HCELL; HUTCH-I; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1	CD44 molecule (Indian blood group)
TCMBANKGE000449	CCK	-	cholecystokinin
TCMBANKGE000468	CTSB	APPS; CPSB; RECEUP	cathepsin B
TCMBANKGE000471	POMC	ACTH; CLIP; LPH; MSH; NPP; OBAIRH; POC	proopiomelanocortin
TCMBANKGE000479	TIMP1	CLGI; EPA; EPO; HCI; TIMP; TIMP-1	TIMP metallopeptidase inhibitor 1
TCMBANKGE000595	ADAM9	CORD9; MCMP; MDC9; Mltng	ADAM metallopeptidase domain 9
TCMBANKGE000723	FOSL2	FRA2	FOS like 2, AP-1 transcription factor subunit
TCMBANKGE000737	PGR	NR3C3; PR	progesterone receptor
TCMBANKGE000844	CYP2E1	CPE1; CYP2E; P450-J; P450C2E	cytochrome P450 family 2 subfamily E member 1
TCMBANKGE000859	PRKCD	ALPS3; CVID9; MAY1; PKCD; nPKC-delta	protein kinase C delta
TCMBANKGE000866	PRKCB	PKC-beta; PKCB; PKCI(2); PKCbeta; PRKCB1; PRKCB2	protein kinase C beta
TCMBANKGE000903	PTGS1	COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS	prostaglandin-endoperoxide synthase 1
TCMBANKGE000973	EGF	HOMG4; URG	epidermal growth factor
TCMBANKGE000986	ERBB2	CD340; HER-2; HER-2/neu; HER2; MLN 19; NEU; NGL; TKR1	erb-b2 receptor tyrosine kinase 2
TCMBANKGE000990	EGFR	ERBB; ERBB1; HER1; NISBD2; PIG61; mENA	epidermal growth factor receptor
TCMBANKGE000994	AKR1B1	ADR; ALDR1; ALR2; AR	aldo-keto reductase family 1 member B
TCMBANKGE001011	TNFSF10	APO2L; Apo-2L; CD253; TL2; TNLG6A; TRAIL	TNF superfamily member 10
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001085	MAPK8	JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1c	mitogen-activated protein kinase 8
TCMBANKGE001107	NOS3	ECNOS; eNOS	nitric oxide synthase 3
TCMBANKGE001118	MMP9	CLG4B; GELB; MANDP2; MMP-9	matrix metallopeptidase 9
TCMBANKGE001145	CDH2	CD325; CDHN; CDw325; NCAD	cadherin 2
TCMBANKGE001161	IL2	IL-2; TCGF; lymphokine	interleukin 2
TCMBANKGE001171	SRC	ASV; SRC1; THC6; c-SRC; p60-Src	SRC proto-oncogene, non-receptor tyrosine kinase
TCMBANKGE001178	STAT3	ADMIO; ADMIO1; APRF; HIES	signal transducer and activator of transcription 3
TCMBANKGE001181	TGFB1	CED; DPD1; IBDIMDE; LAP; TGF-beta1; TGFB; TGFbeta	transforming growth factor beta 1
TCMBANKGE001183	TRPV4	BCYM3; CMT2C; HMSN2C; OTRPC4; SMAL; SPSMA; SSQTL1; TRP12; VRL2; VROAC	transient receptor potential cation channel subfamily V member 4
TCMBANKGE001194	ADRA2A	ADRA2; ADRA2R; ADRAR; ALPHA2AAR; ZNF32	adrenoceptor alpha 2A
TCMBANKGE001197	FOS	AP-1; C-FOS; p55	Fos proto-oncogene, AP-1 transcription factor subunit
TCMBANKGE001506	ADRA1B	ADRA1; ALPHA1BAR	adrenoceptor alpha 1B
TCMBANKGE001943	ADRA1D	ADRA1; ADRA1A; ADRA1R; ALPHA1; DAR; dJ779E11.2	adrenoceptor alpha 1D
TCMBANKGE003046	AVP	ADH; ARVP; AVP-NPII; AVRP; VP	arginine vasopressin
TCMBANKGE003245	PDGFB	IBGC5; PDGF-2; PDGF2; SIS; SSV; c-sis	platelet derived growth factor subunit B
TCMBANKGE003960	CD82	4F9; C33; GR15; IA4; KAI1; R2; SAR2; ST6; TSPAN27	CD82 molecule
TCMBANKGE004151	PRL	GHA1	prolactin
TCMBANKGE004205	PLD1	CVDD	phospholipase D1
TCMBANKGE004793	WNT5A	hWNT5A	Wnt family member 5A
TCMBANKGE005487	DGKZ	DAGK5; DAGK6; DGK-ZETA; hDGKzeta	diacylglycerol kinase zeta
TCMBANKGE006147	EFEMP1	DHRD; DRAD; FBLN3; FBNL; FIBL-3; MLVT; MTLV; S1-5	EGF containing fibulin extracellular matrix protein 1
TCMBANKGE006494	PRKCG	PKC-gamma; PKCC; PKCG; PKCI(3); PKCgamma; SCA14	protein kinase C gamma
TCMBANKGE006598	DCD	AIDD; DCD-1; DSEP; HCAP; PIF	dermcidin
TCMBANKGE007054	C8B	C82	complement C8 beta chain
TCMBANKGE007886	HLA-G	MHC-G	major histocompatibility complex, class I, G
TCMBANKGE008056	ADRA2C	ADRA2L2; ADRA2RL2; ADRARL2; ALPHA2CAR	adrenoceptor alpha 2C
TCMBANKGE008183	ACE	ACE1; CD143; DCP; DCP1	angiotensin I converting enzyme
TCMBANKGE008891	ODC1	ODC	ornithine decarboxylase 1
TCMBANKGE009995	ACTG1	ACT; ACTG; DFNA20; DFNA26; HEL-176	actin gamma 1
TCMBANKGE010343	TRHR	CHNG7; TRH-R	thyrotropin releasing hormone receptor
TCMBANKGE012672	SLC9A1	APNH; LIKNS; NHE-1; NHE1; PPP1R143	solute carrier family 9 member A1
TCMBANKGE013265	TDG	hTDG	thymine DNA glycosylase
TCMBANKGE013739	PRKCQ	PRKCT; nPKC-theta	protein kinase C theta
TCMBANKGE014423	ADRA1A	ADRA1C; ADRA1L1; ALPHA1AAR	adrenoceptor alpha 1A
TCMBANKGE014473	CRH	CRF; CRH1	corticotropin releasing hormone
TCMBANKGE014489	CYP11A1	CYP11A; CYPXIA1; P450SCC	cytochrome P450 family 11 subfamily A member 1
TCMBANKGE014498	XDH	XAN1; XO; XOR	xanthine dehydrogenase

药名:

phorbol 12-myristate 13-acetate

分子式:

C8H8HgO2

Smiles:

CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C

成分:

HBIN039602; HBIN039609; HBIN000982

SymMap_id:

SMIT17196

TCMID_id:

32011; 17173

PubChem_id:

27924