Compound Summary


  Compound Information

药名:

donasine

分子式:

C11H14N2

Smiles:

CN(C)CC1=CNC2=CC=CC=C21

成分:

HBIN024407;HBIN028365;HBIN028364

OB_score:

60.140911

CAS_id:

87-52-5

SymMap_id:

SMIT06466;SMIT15676

TCMID_id:

37314;8970

TCMSP_id:

MOL004573

PubChem_id:

6890


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE001065 Dioscorea futschauensis To dispel wind-damp, disinhibit damp and turbidity, disperse swelling toxin./Wind-damp impediment pain, strangury with pain, white turbidity, leukorrhea, damp sore.
TCMBANKHE003648 folium citri tangerie 橘叶 Regulation of qi
TCMBANKHE005809 Dioscorea parviflora 小花盾叶薯蓣 To clear heat and resolve toxin, quicken blood and disperse swelling./Swelling toxin of welling abscess and boil, soft tissue sprain, bee sting, insect bites.
TCMBANKHE004685 Dioscorea althaeoides 蜀葵叶薯蓣 To course wind and dispel damp, fortify spleen and disperse food, quicken blood and disperse swelling./common cold with headache, wind-damp impediment pain, food accumulation distention and fullness, indigestion, knocks and falls.
TCMBANKHE006919 flos farfarae 款冬花 To relieve cough and resolve phlegm to nourish the lung to keep the adverse qi downward./Cough, cough and asthma with abundant phlegm, consumption cough and hemoptysis, chronic bronchitis, infection of upper respiratory tract, tuberculosis.
TCMBANKHE005566 Phalaris arundinacea 刈草,虉草 To regulate menstruation and check discharge./Menstrual disorder, red and white vaginal discharge.
TCMBANKHE005625 Acer rubrum 红花槭
TCMBANKHE006158 Dioscorea zingiberensis 盾叶薯蓣 To clear lung and relieve cough, disinhibit damp and free strangury, free network vessels and relieve pain, resolve toxin and disperse swelling./Lung heat cough, damp-heat strangury pain, wind-damp lumbago, swollen welling abscess and malign sore, sprain from knocks and falls, bee sting, insect bites.
TCMBANKHE008402 Dioscorea gracillima 纤细薯蓣 See Dioscorea hypoglauca./See Dioscorea hypoglauca.
TCMBANKHE008744 Tribulus terrestris 刺蒺藜 To dissipate wind and brighten eyes, precipitate qi and move blood./Headache, itchy body, red eyes and eye screen, convulsion, fullness in chest, cough and counterflow, concretion and conglomeration, difficult lactation, welling abscess and flat abscess, scrofula.
TCMBANKHE008332 绵萆薢 Strangury with white turbidity, excessive leukorrhea, damp-heat sore toxin, impediment pain in lumbus and knees.
TCMBANKHE008337 Acer saccharinum 银白槭
TCMBANKHE007606 菝葜 Wind-damp impediment pain, strangury-turbidity, vaginal discharge, dysentery, diarrhea, swelling toxin of welling abscess and sore, intractable lichen, burns and scalds.
TCMBANKHE005494/YEM-445 Fructus Hordei Germitus|Hordeum vulgare L. 麦芽|大麦 大麦 云南民族药物志:第三卷 To invigo rate the function of the spleen, to regulate the function of the stomach, and to promote the flow of milk./Food accumulation, abdominal distention and diarrhea, nausea and vomiting, inappetence, galactostasis, distending pain in breast. 佤族/彝族
TCMBANKHE005864/YEM-477 Loropetalum chinense|Loropetalum chinense(R.Br.)Oliver 继木|檵木 檵木 云南民族药物志:第三卷 To clear heat and relieve cough, promote contraction and stanch bleeding./Angina pectoris, senile bronchitis, indigestion, duodenal bleeding, uterine bleeding, lung heat cough, hemoptysis, spontaneous external bleeding, hematochezia, dysentery, diarrhea, flooding and spotting, infection of skin. 水族
TCMBANKHE006634/YNS-20/YEM-636 Costus speciosus|Costus speciosus (Koen.) Smith|Costus speciosus(Koen.)Smith 樟柳头|闭鞘姜 闭鞘姜 云南药材标准:第五册|云南民族药物志:第四卷 除风解毒,利咽化痰,活血止痛,利水消肿,用于咽喉肿痛,咳喘痰多,痄腮,耳道溢脓,风湿痹痛,水肿,小便热涩疼痛,胆汁病(黄疸病,白疸病,黑疸病)|To move water and disperse swelling./Ascites, white turbidity, swollen welling abscess, malign sore. 阿昌族/傣族/德昂族/哈尼族/基诺族/景颇族/拉祜族/傈僳族/佤族/瑶族/壮族
TCMBANKHE006677/YEM-899 Arundo donax|Arundo donax L. 芦竹根|芦竹 芦竹 云南民族药物志:第五卷 To clear heat and drain fire, engender liquid and eliminate vexation, disinhibit urine./Febrile diseases with vexation and thirst, vacuity taxation with steaming bone, blood ejection, heat strangury, inhibited urination, wind-fire toothache. 阿昌族/傣族/德昂族/基诺族/景颇族/傈僳族/佤族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000309 SCN5A CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 sodium voltage-gated channel alpha subunit 5
TCMBANKGE000425 DRD1 DADR; DRD1A dopamine receptor D1
TCMBANKGE000633 ADRB2 ADRB2R; ADRBR; B2AR; BAR; BETA2AR adrenoceptor beta 2
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001194 ADRA2A ADRA2; ADRA2R; ADRAR; ALPHA2AAR; ZNF32 adrenoceptor alpha 2A
TCMBANKGE001467 LTA4H - leukotriene A4 hydrolase
TCMBANKGE001506 ADRA1B ADRA1; ALPHA1BAR adrenoceptor alpha 1B
TCMBANKGE001755 MAOB - monoamine oxidase B
TCMBANKGE001943 ADRA1D ADRA1; ADRA1A; ADRA1R; ALPHA1; DAR; dJ779E11.2 adrenoceptor alpha 1D
TCMBANKGE003157 CHRM2 HM2 cholinergic receptor muscarinic 2
TCMBANKGE003625 SLC6A4 5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT solute carrier family 6 member 4
TCMBANKGE005535 CHRM1 HM1; M1; M1R cholinergic receptor muscarinic 1
TCMBANKGE006943 CHRM3 EGBRS; HM3; PBS cholinergic receptor muscarinic 3
TCMBANKGE008056 ADRA2C ADRA2L2; ADRA2RL2; ADRARL2; ALPHA2CAR adrenoceptor alpha 2C
TCMBANKGE009256 SLC6A2 NAT1; NET; NET1; SLC6A5 solute carrier family 6 member 2
TCMBANKGE012155 SLC6A3 DAT; DAT1; PKDYS; PKDYS1 solute carrier family 6 member 3
TCMBANKGE014050 GABRA1 ECA4; EIEE19; EJM; EJM5 gamma-aminobutyric acid type A receptor subunit alpha1
TCMBANKGE014423 ADRA1A ADRA1C; ADRA1L1; ALPHA1AAR adrenoceptor alpha 1A
TCMBANKGE014790 ADRB1 ADRB1R; B1AR; BETA1AR; FNSS2; RHR adrenoceptor beta 1