Compound Summary


  Compound Information

药名:

atroscine

分子式:

C17H21NO4

Smiles:

CN1C2CC(CC1C3C2O3)OC(=O)C(CO)C4=CC=CC=C4

成分:

HBIN017336;HBIN029809

OB_score:

71.926678;49.840226

CAS_id:

138-12-5

SymMap_id:

SMIT03948;SMIT00817

TCMID_id:

24334;10869

TCMSP_id:

MOL001553;MOL011519

PubChem_id:

9916237


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE001367 Semen Hyoscyami 天仙子 To relieve spasm and pain, and to cause tranquilization./1. Antisudorific, saliva antisecretory and mydriatic.2. Relaxing the smooth muscles.3. Increasing heart rate and exciting the respiratory center.
TCMBANKHE003754 Hyoscyamus niger 莨菪子 To resolve spasm and relieve pain, quiet heart and settle epilepsy./Pain in stomach duct and abdomen, wind-damp impediment pain, decayed toothache due to wind, painful wound from knocks and falls, incessant asthma and cough, prolapse of rectum due to diarrhea, mania and withdrawal, fright epilepsy, swelling toxin of welling abscess and sore.
TCMBANKHE006321 Anisodus tanguticus [Syn. Scopolia tangutica ] 藏茄 To anesthetize and settle pain, resolve tetany and disperse swelling./Shock, shock due to acute infectious diseases, cerebral thrombosis, acute spinal cord inflammation, spasm of biliary ducts or duodenum, acute gastroenteritis, chronic gastroenteritis, contracturepain in stomach duct and abdomen, ascaridosis in biliary tract, gallstones, swelling toxin of welling abscess and flat abscess, knocks and falls, fracture.
TCMBANKHE004922 Datura innoxia 毛曼陀罗叶 See Datura metel./See Datura metel.
TCMBANKHE005172 Datura innoxia 毛曼陀罗根 See Datura metel./See Datura metel.
TCMBANKHE005371 Scopolia japonica 东莨菪碱 To resolve tetany and settle pain, constrain sweat and astringe intestines./Various pains, mental manic agitation, swelling toxin of sore and welling abscess, anthrax, bleeding due to external injury, body lichen.
TCMBANKHE005731 石上柏 To clear heat and dampness, promote blood circulation and remove blood stasis: For jaundice of dampness-heat type and abdominal mass. Recently used for acute and chronic hepatitis, cirrhosis, cholecysitis, etc., also for diarrhea, desentery and leucorrhag
TCMBANKHE008780 Scopolia carniolica 欧莨菪
TCMBANKHE006426 Flos Daturae 洋金花 To relieve asthma and cough, to alleviate pain, and to arrest spasm./Cough and asthma without phlegm, cold pain in heart and Datura stramonium .
TCMBANKHE006542 Scopolia carniolica 欧莨菪
TCMBANKHE006561 Sus scrofa domestica 猪胆 To clear heat and resolve toxin, moisten dryness./Febrile diseases with vexation and thirst, constipation, jaundice, pertussis, asthma, diarrhea, dysentery, red eyes, throat impediment, otitis media, swollen welling abscess and clove sores.
TCMBANKHE008772 Hyoscyamus niger 莨菪叶 To settle pain and resolve tetany./Pain in stomach duct and abdomen, toothache, cough and asthma.
TCMBANKHE005737/YEM-273 Datura metel|Datura metel L. 曼陀罗叶|洋金花 洋金花 云南民族药物志:第二卷 To suppress cough and calm asthma, relieve pain and draw out pus./Cough and asthma, impediment pain, beriberi, prolapse of rectum. 傣族/傈僳族/彝族/壮族
TCMBANKHE006663/YNS-163/YEM-260/YEM-273 Datura metel|Datura stramonium L.|Datura metel L. 曼陀罗根|曼陀罗叶|洋金花 曼陀罗叶|洋金花 云南药材标准:第一册|云南民族药物志:第二卷 平喘止咳,散寒止痛。用于喘咳,脘腹疼痛,痛经,寒湿痹痛。|To suppress cough, relieve pain, draw out pus./Cough and asthma, wind-damp impediment pain, boil and lichen, malign sore, rabid dog bite. 阿昌族/白族/傣族/德昂族/景颇族/傈僳族/纳西族/佤族/藏族/彝族/壮族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000309 SCN5A CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 sodium voltage-gated channel alpha subunit 5
TCMBANKGE000425 DRD1 DADR; DRD1A dopamine receptor D1
TCMBANKGE000633 ADRB2 ADRB2R; ADRBR; B2AR; BAR; BETA2AR adrenoceptor beta 2
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000869 DRD2 D2DR; D2R dopamine receptor D2
TCMBANKGE001506 ADRA1B ADRA1; ALPHA1BAR adrenoceptor alpha 1B
TCMBANKGE001943 ADRA1D ADRA1; ADRA1A; ADRA1R; ALPHA1; DAR; dJ779E11.2 adrenoceptor alpha 1D
TCMBANKGE003157 CHRM2 HM2 cholinergic receptor muscarinic 2
TCMBANKGE003625 SLC6A4 5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT solute carrier family 6 member 4
TCMBANKGE005535 CHRM1 HM1; M1; M1R cholinergic receptor muscarinic 1
TCMBANKGE006943 CHRM3 EGBRS; HM3; PBS cholinergic receptor muscarinic 3
TCMBANKGE008056 ADRA2C ADRA2L2; ADRA2RL2; ADRARL2; ALPHA2CAR adrenoceptor alpha 2C
TCMBANKGE008124 ADRA2B ADRA2L1; ADRA2RL1; ADRARL1; ALPHA2BAR; FAME2; alpha-2BAR adrenoceptor alpha 2B
TCMBANKGE008702 OPRM1 LMOR; M-OR-1; MOP; MOR; MOR1; OPRM opioid receptor mu 1
TCMBANKGE009256 SLC6A2 NAT1; NET; NET1; SLC6A5 solute carrier family 6 member 2
TCMBANKGE009455 CHRM5 HM5 cholinergic receptor muscarinic 5
TCMBANKGE011923 CHRM4 HM4; M4R cholinergic receptor muscarinic 4
TCMBANKGE012155 SLC6A3 DAT; DAT1; PKDYS; PKDYS1 solute carrier family 6 member 3
TCMBANKGE014050 GABRA1 ECA4; EIEE19; EJM; EJM5 gamma-aminobutyric acid type A receptor subunit alpha1
TCMBANKGE014423 ADRA1A ADRA1C; ADRA1L1; ALPHA1AAR adrenoceptor alpha 1A
TCMBANKGE014625 OPRD1 DOP; DOR; DOR1; OPRD opioid receptor delta 1