Compound Summary


  Compound Information

药名:

cryptopine

分子式:

C21H23NO5

Smiles:

CN1CCC2=CC(=C(C=C2C(=O)CC3=C(C1)C4=C(C=C3)OCO4)OC)OC

成分:

HBIN021792;HBIN021791;HBIN042678

OB_score:

78.742645

CAS_id:

482-74-6

SymMap_id:

SMIT01355;SMIT03873

TCMID_id:

4289;33566

TCMSP_id:

MOL001460

PubChem_id:

72616


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000003 Oleum Fecoris Piscis 鱼肝油
TCMBANKHE002730 橘络
TCMBANKHE002762 Radix et Rhizoma Thalictri 马尾莲 Influenza, fever in children, common cold with fever, measles papules, malaria, damp-heat diarrhea dysentery, jaundice, red eyes with gall.
TCMBANKHE003755 Radix Ampelopsis 白蔹 To remove toxic heat, to cure carbuncles, and to reduce nodules./Swelling toxin of sore and welling abscess, burns and scalds, scrofula, damp sore, warm malaria, frightepilepsy, blood dysentery, intestinal wind, hemorrhoids and fistulas, leukorrhea, knocks and falls, bleeding due to external injury.
TCMBANKHE003901 Argemone mexicana 蓟罂粟 To effuse sweat and disinhibit water, clear heat and resolve toxin, relieve pain and itch./Common cold without sweating, jaundice, strangury, edema, eyelid laceration, mounting qi , scab and lai, syphilis.
TCMBANKHE003990 Folium Llicis Chinensis 四季青 To clearheat and toxic materials./Angina pectoris, coronary heart disease, thrombophlebitis, thromboangiitis obliterans (Buerger’s disease), lung heat cough, swelling pain in throat, dysentery, diarrhea, infection of biliary tract , urinary tract infection, burns and scalds, heat toxin swollen welling abscess, ulcer of lower limb, eczema, frostbite, cracking, wound, bleeding due to external injury.
TCMBANKHE005792 Thalictrum petaloideum 瓣蕊唐松草 To clear heat, dry damp, resolve toxin./Damp-heat diarrhea dysentery, jaundice, lung heat cough, red eyes with gall, swelling welling abscess and sore and boil, exudative dermatitis
TCMBANKHE004415 Fumaria officinalis 药用球果紫堇
TCMBANKHE004522 Rhizoma Corydalis 延胡索 1. To invigorate blood and promote qi circulation; 2. To stop pain/Chest and rib-side pain, pain in stomach duct and abdomen, neuralgia, gastrointestinal spasm, amenorrhea and dysmenorrhea, postpartum stasis stagnation abdominal pain, painful swelling from knocks and falls.
TCMBANKHE004577 pericarpium papaveris 罂粟壳 1. Astringe the intestine, relieve diarrhea and alleviate pain. 2. Astringe the lung and relieve cough./Enduring cough, chronic diarrhea, prolapse of rectum, pain in stomach duct and abdomen.
TCMBANKHE004901 Dicentra spectabilis 荷包牡丹根 To dispel wind, quicken blood, settle pain./Incised wound, sore toxin, stomachache.
TCMBANKHE007245 Hylomecon japonica 荷青花 To dispel wind and free network vessels, dissipate stasis and disperse swelling./Wind-damp impediment pain, knocks and falls.
TCMBANKHE005699 Rhizoma Corydalis 廷胡索;廷胡;玄胡;元胡;元胡索;玄胡素 For stagnation of vital energy or blood stasis resulting in headache, chest pain, hypochondriac pain, epigastric pain, abdominal pain, backache, arthralgia, dysmenorrhea or trauma. Recently, alos used for angina pectoris, peptic ulcer and neuralgia./1. Its components d-corydaline and d1-tetrahydropalmatine are analgesics.2. Decreasing the secretion of gastric juice and the amount of pepsin.
TCMBANKHE007813 Corydalis pallida 菊花黄连 To clear heat and resolve toxin, disperse swelling and relieve pain./Welling abscess and boil, innominate toxin swelling.
TCMBANKHE006124 Fumaria parviflora 小花球果紫堇
TCMBANKHE006154 Thalictrum faberi 大叶唐松草 To clear heat, drain fire, resolve toxin./Dysentery, diarrhea, red eyes with gall, damp-heat jaundice.
TCMBANKHE006371 白屈菜 Pain in sensory nerve endings, pain from ulcer in digestive tract, stomachache, abdominal pain, enteritis, dysentery, chronic bronchitis, pertussis, cough, jaundice, edema, ascites, scab and lichen with swelling of sores, snake or insect bites.
TCMBANKHE007173 Thalictrum atriplex 狭序唐松草 To clear heat and resolve toxin, cool liver, check dysentery./Swelling and toxin of sore and welling abscess, damp-heat jaundice, dysentery, conjunctivitis.
TCMBANKHE007977 Thalictrum thunbergii 烟锅草 To clear heat and resolve toxin, dry damp./Pertussis, toothache, swelling toxin of welling abscess and sore, acute dermitis, eczema.
TCMBANKHE007781 Herba Asari 细辛 To dispel wind-cold, to relieve nasal obstruction, to alleviate pain and to remove retained fluid./Wind-cold common cold, influenza, headache, toothache, local anesthesia, nasal congestion, deep-source nasal congestion, wind-damp impediment pain, phlegm-rheum cough asthma.
TCMBANKHE008122 Thalictrum microgynum 小果唐松草 To clear heat and resolve toxin, disinhibit damp./Yellow swelling in whole body, yellow eyes, knocks and falls.
TCMBANKHE007520 Fructus Amomi 砂仁 To eliminate damp and improve appetite, to warm the spleen and check diarrhea, and to prevent abortion./Abdominal pain glomus distention, food stagnation in torpid stomach, dysphagia-occlusion, vomiting, cold dysentery, stirring fetus in pregnancy.
TCMBANKHE008723/XU-511 Thalictrum glandulosissimum 金丝马尾连 湖北省远安县荷花镇 See Thalictrum foliolosum./See Thalictrum foliolosum.
TCMBANKHE000631/YEM-135 herba meconpsis integrifoliae|Meconopsis integrifolia(Maxim.) Franch. 绿绒蒿|全缘叶绿绒蒿 全缘叶绿绒蒿 云南民族药物志:第一卷 傈僳族/藏族
TCMBANKHE006850/YEM-509 Papaver somniferum|Papaver somniferum L. 罂粟 罂粟 云南民族药物志:第三卷 To fortify spleen and promote digestion, clear heat and disinhibit urine./Stomach reflux, abdominal pain, diarrhea, prolapse of rectum. 傣族/基诺族/佤族/彝族
TCMBANKHE006476/YEM-509 Papaver somniferum|Papaver somniferum L. 鸦片|罂粟 罂粟 云南民族药物志:第三卷 To relieve pain, astringe intestines, suppress cough./Pain in heart and abdomen, chronic diarrhea, chronic dysentery, dry cough without phlegm. 傣族/基诺族/佤族/彝族
TCMBANKHE004691/YEM-353/YEM-961 Fructus Amomi|Amomum villosum Lour. 缩砂仁; 砂仁|阳春砂 阳春砂仁 云南民族药物志:第五卷 Treatment of accumulation of damp in the spleen and the stomach marked by epigastric stuffieness and anorexia, vomiting and diarrhea in deficiency cold syndrome of the spleen and the stomach, pernicious vomiting of pregnancy, threatened abortion.; To eliminate damp and improve appetite, to warm the spleen and check diarrhea, and to prevent abortion./1. Its decoction lower thab 1% concentration stimulates and that higher than 1% or the saturated solution of its volatile oil inhibits the intestines of guinea-pigs in vitro.2. Its volatile oil acts as stomachic tonic and exaggerates the diacharge of flatus.; Abdominal pain glomus distention, food stagnation in torpid stomach, dysphagia-occlusion, vomiting, cold dysentery, stirring fetus in pregnancy. 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/瑶族/彝族/壮族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000121 KCNH2 ERG-1; ERG1; H-ERG; HERG; HERG1; Kv11.1; LQT2; SQT1 potassium voltage-gated channel subfamily H member 2
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE000309 SCN5A CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 sodium voltage-gated channel alpha subunit 5
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000425 DRD1 DADR; DRD1A dopamine receptor D1
TCMBANKGE000474 NCOA1 F-SRC-1; KAT13A; RIP160; SRC1; bHLHe42; bHLHe74 nuclear receptor coactivator 1
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000633 ADRB2 ADRB2R; ADRBR; B2AR; BAR; BETA2AR adrenoceptor beta 2
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000766 ACHE ACEE; ARACHE; N-ACHE; YT acetylcholinesterase (Cartwright blood group)
TCMBANKGE000784 CALM3 CALM; CAM1; CAM2; CAMB; CPVT6; CaM; CaMIII; HEL-S-72; LQT16; PHKD; PHKD3 calmodulin 3
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE000979 KDR CD309; FLK1; VEGFR; VEGFR2 kinase insert domain receptor
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE001506 ADRA1B ADRA1; ALPHA1BAR adrenoceptor alpha 1B
TCMBANKGE001943 ADRA1D ADRA1; ADRA1A; ADRA1R; ALPHA1; DAR; dJ779E11.2 adrenoceptor alpha 1D
TCMBANKGE003625 SLC6A4 5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT solute carrier family 6 member 4
TCMBANKGE003643 F7 SPCA coagulation factor VII
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE005535 CHRM1 HM1; M1; M1R cholinergic receptor muscarinic 1
TCMBANKGE006943 CHRM3 EGBRS; HM3; PBS cholinergic receptor muscarinic 3
TCMBANKGE008702 OPRM1 LMOR; M-OR-1; MOP; MOR; MOR1; OPRM opioid receptor mu 1
TCMBANKGE008723 PDE10A ADSD2; HSPDE10A; IOLOD; LINC00473; PDE10A19 phosphodiesterase 10A
TCMBANKGE009294 HTR3A 5-HT-3; 5-HT3A; 5-HT3R; 5HT3R; HTR3 5-hydroxytryptamine receptor 3A
TCMBANKGE009455 CHRM5 HM5 cholinergic receptor muscarinic 5
TCMBANKGE009758 PDE3A CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB phosphodiesterase 3A
TCMBANKGE009951 CACNA1S CACNL1A3; CCHL1A3; Cav1.1; HOKPP; HOKPP1; MHS5; TTPP1; hypoPP calcium voltage-gated channel subunit alpha1 S
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1
TCMBANKGE011923 CHRM4 HM4; M4R cholinergic receptor muscarinic 4
TCMBANKGE014625 OPRD1 DOP; DOR; DOR1; OPRD opioid receptor delta 1