Compound Summary


  Compound Information

药名:

roemerine

别名:

ZINC32273181; 5H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinolin-11-ol, 6,7,7a,8-tetrahydro-7-methyl-, (7aR)- 6a-beta-Aporphine, 1,2-(methylenedioxy)-; (-)-Aporheine; STOCK1N-07907; Remerine; Remerine (alkaloid); Roemerin; CCRIS 3809; l-Roemerine; 548-08-3; NCGC00163613-01; 5H-Benzo(g)-1,3-benzodioxolo(6,5,4-de)quinoline, 6,7,7a,8-tetrahydro-7-methyl-, (7aR)-; (7aR)-7-Methyl-6,7,7a,8-tetrahydro-5H-benzo(g)-1,3-benzodioxolo(6,5,4-de)quinoline;Remerin

分子式:

C18H17NO2

Smiles:

CN1CCC2=CC3=C(C4=C2C1CC5=CC=CC=C54)OCO3

成分:

HBIN042389; HBIN042070

OB_score:

40.754916

CAS_id:

548-08-3

SymMap_id:

SMIT17490; SMIT08695

TCMID_id:

18881

TCMSP_id:

MOL007218

PubChem_id:

119204


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE002277 荷花
TCMBANKHE004791 Herba Spirodelae 浮萍 To dispel wind-heat, to promote eruption, and to cause diuresis./Wind-heat exterior syndrome, non-eruption of measles, dormant papules with pruritus, edema, dribbling urinary block, sore and lichen, erysipelas, scalds.
TCMBANKHE004964 Agave east - one 剑麻
TCMBANKHE007143 Agave americana 番麻 To resolve toxin and draw out pus, kill worms, stanch bleeding./Sores with welling abscess and flat abscess, scab and lichen, pelvic inflammation, flooding.
TCMBANKHE008256 Agave east - one 东一号剑麻
TCMBANKHE005111/YEM-104 Nelumbo nucifera|Nelumbo nucifera Gaertn. 荷叶蒂|莲 云南民族药物志:第一卷 To clear summerheat and eliminate damp, dispel stasis and stanch bleeding, quiet fetus./Summerheat-damp diarrhea, blood dysentery, flooding and spotting, stirring fetus in pregnancy. 阿昌族/傣族/德昂族/景颇族/傈僳族/彝族/藏族
TCMBANKHE008259/YEM-104 Nelumbo nucifera|Nelumbo nucifera Gaertn. 荷梗|莲 云南民族药物志:第一卷 To dispel summerheat, rectify qi and transform damp./Summerheat-damp and oppression in chest, diarrhea, dysentery, strangury, Vaginal discharge. 阿昌族/傣族/德昂族/景颇族/傈僳族/彝族/藏族
TCMBANKHE005257/YEM-104 Folium Nelumbinis|Nelumbo nucifera Gaertn. 荷叶|莲 云南民族药物志:第一卷 To relieve summer-heat, to invigorate the spleen function of the spleen and arrest bleeding by reducing heat in blood./Summerheat-heat vexation and thirst, summerheat-damp diarrhea, spleen vacuity diarrhea, blood heat, blood ejection, spontaneous external bleeding, hematochezia, flooding and spotting. 阿昌族/傣族/德昂族/景颇族/傈僳族/彝族/藏族
TCMBANKHE008257/YEM-229 Agave sisalana|Agave sisalana Perr ex Engelm. 剑麻 剑麻 云南民族药物志:第二卷 傣族/哈尼族/佤族
TCMBANKHE004965/YEM-229 Agave sisalana|Agave sisalana Perr ex Engelm. 剑麻;琼麻|剑麻 剑麻 云南民族药物志:第二卷 To cool blood and stanch bleeding, resolve toxin and disperse swelling./Tuberculosis and hemoptysis, spontaneous external bleeding, hematochezia, dysentery, welling abscess, hemorrhoids. 傣族/哈尼族/佤族
TCMBANKHE005228/YEM-235 Cortex Magnoliae officilis;Magnolia officinalis|Magnolia officinalis Rehd.et Wils. 厚朴 厚朴 云南民族药物志:第二卷 To eliminate damp and relieve distension;To dry damp and disperse phlegm, precipitate qi and eliminate fullness, lower blood pressure./1. Broad-spectrum antibacterial.2. Magnocurarine, one of the active components, can relaxstriated muscles.3. Its decoction stimulates the smooth muscles of intestines and bronchii in rabbits in vitro.4. Magnocuraine may also lower blood pressure and accelerate heart rate.5.Amebic dysentery, vomiting and diarrhea, food accumulation and qi stagnation, abdominal distention and constipation, phlegm-rheum cough asthma. 彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000309 SCN5A CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 sodium voltage-gated channel alpha subunit 5
TCMBANKGE000633 ADRB2 ADRB2R; ADRBR; B2AR; BAR; BETA2AR adrenoceptor beta 2
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000766 ACHE ACEE; ARACHE; N-ACHE; YT acetylcholinesterase (Cartwright blood group)
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE000965 CHRNA7 CHRNA7-2; NACHRA7 cholinergic receptor nicotinic alpha 7 subunit
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001506 ADRA1B ADRA1; ALPHA1BAR adrenoceptor alpha 1B
TCMBANKGE001943 ADRA1D ADRA1; ADRA1A; ADRA1R; ALPHA1; DAR; dJ779E11.2 adrenoceptor alpha 1D
TCMBANKGE003625 SLC6A4 5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT solute carrier family 6 member 4
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE005535 CHRM1 HM1; M1; M1R cholinergic receptor muscarinic 1
TCMBANKGE006943 CHRM3 EGBRS; HM3; PBS cholinergic receptor muscarinic 3
TCMBANKGE008700 CHRNA2 - cholinergic receptor nicotinic alpha 2 subunit
TCMBANKGE008702 OPRM1 LMOR; M-OR-1; MOP; MOR; MOR1; OPRM opioid receptor mu 1
TCMBANKGE008921 RXRA NR2B1 retinoid X receptor alpha
TCMBANKGE009294 HTR3A 5-HT-3; 5-HT3A; 5-HT3R; 5HT3R; HTR3 5-hydroxytryptamine receptor 3A
TCMBANKGE009455 CHRM5 HM5 cholinergic receptor muscarinic 5
TCMBANKGE014050 GABRA1 ECA4; EIEE19; EJM; EJM5 gamma-aminobutyric acid type A receptor subunit alpha1
TCMBANKGE014625 OPRD1 DOP; DOR; DOR1; OPRD opioid receptor delta 1