Compound Summary


  Compound Information

药名:

Phytodolor

别名:

AIDS348374; 7-hydroxy-6,8-dimethoxychromen-2-one; NSC324637; ISOFRAXIDIN B814484K143; 7-hydroxy-6,8-dimethoxy-chromen-2-one; NSC 324637; 2H-1-Benzopyran-2-one, 7-hydroxy-6,8-dimethoxy-; Umbelliferone, 6,8-dimethoxy-; 7-Hydroxy-6,8-dimethoxy-2H-1-benzopyran-2-one; AIDS-348374; BRN 0202652; 7-hydroxy-6,8-dimethoxy-2-chromenone; 2H-1- Benzopyran-2-one, 7-hydroxy-6,8-dimethoxy-; 7-hydroxy-6,8-dimethoxy-coumarin; Isofraxidin; 486-21-5; 5-18-04-00332 (Beilstein Handbook Reference); Coumarin, 7-hydroxy-6,8-dimethoxy-; isofraxidin; 486I215; AC-8051; Q-100542; SCHEMBL3924718; 7-hydroxy-6,8-dimethoxychromen-2-one; HOEVRHHMDJKUMZ-UHFFFAOYSA-N; UNII-304915F056; NSC324637; V1549; 6,8-dimethoxy-7-hydroxycoumarin; ISOFRAXIDIN B814484K143; 7-hydroxy-6,8-dimethoxy-1-benzopyran-2-one; Isofraxidin, analytical standard; 7-hydroxy-6,8-dimethoxy-chromen-2-one; C17480; NSC 324637; 2H-1-Benzopyran-2-one,7-hydroxy-6,8-dimethoxy-; CTK8E5534; SC-17017; 2H-1-Benzopyran-2-one, 7-hydroxy-6,8-dimethoxy-; Umbelliferone, 6,8-dimethoxy-; 7-Hydroxy-6,8-dimethoxy-2H-1-benzopyran-2-one; CHEMBL451518; AC1NSX0O; Phytodolor; 6,8-dimethoxy-7-oxidanyl-chromen-2-one; FT-0688350; Ambotz486-21-5; TR-017709; A827571; NSC-324637; 6,8-Dimethoxyumbelliferone; AN-8405; DTXSID70197557; I14-19008; BRN 0202652; 7-Hydroxy-6,8-dimethoxycoumarin; LS-39687; FT-0698467; BG01525210; Isofraxidin; AKOS000278010; 486-21-5; 5-18-04-00332 (Beilstein Handbook Reference); MCULE-8927053707; ZINC1573299; 304915F056; Coumarin, 7-hydroxy-6,8-dimethoxy-; CHEBI:81121; W-2732; MolPort-000-882-100

分子式:

C11H10O5

Smiles:

COC1=C(C(=C2C(=C1)C=CC(=O)O2)OC)O

成分:

HBIN039790; HBIN030748

OB_score:

52.317863; 39.745686

CAS_id:

486-21-5

SymMap_id:

SMIT07443; SMIT00314

TCMID_id:

11425

TCMSP_id:

MOL005723; MOL011745

PubChem_id:

5318565


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000516 Herba Sarcatidrae 肿节风 1. Inhibiting the growth of Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella typhosa and various Shigella dysenteriae in vitro. 2. Nonspecfic anti-inflammatory and promoting the repair of gastric ulcer. 3. Its volatile oil and flavones inhibit sa/1. To clear heat and toxic material. For carbuncle due to intensive heat, aphthae, gingivitis, dysentery, filariasis, etc. 2. To promote blood circulation and remove blood stasis, expel wind and dredge channels. For trauma, rheumatism, stomachache. Recent
TCMBANKHE001004 牛尾蒿
TCMBANKHE002206 罗布麻叶
TCMBANKHE002623 铁线透骨草
TCMBANKHE003846 Adiantum pedatum 铁丝七 To clear heat and resolve toxin, disinhibit water and free strangury./Lung heat cough, dysentery, jaundice, dribbling and inhibited voidings of urination, swollen welling abscess, scrofula, scalds.
TCMBANKHE004123 Medicinal Indianmulberry 巴戟天 Neurasthenia, impotence and emission, cold pain in abdomen, urinary incontinence, vacuity cold of uterus, wind-cold-damp impediment, aching in lumbus and knees.
TCMBANKHE008294 泽漆 Edema and qi fullness, phlegm-rheum cough asthma, malaria, bacillary dysentery, scrofula, tuberculous fistula, medullitis.
TCMBANKHE008517 Folium Artemisiae Argyi 艾叶 1. To warm the channels and stop bleeding. 2. To dispel cold and stop pain/Cold pain in abdomen, menstrual disorder due to cold, infertility due to uterus cold, blood ejection, spontaneous external bleeding, flooding and spotting, fetal spotting, itchy skin.
TCMBANKHE009061 Acanthopanax senticosus [Syn. Eleutherococcus senticosus ] 刺五加 To boost qi and fortify spleen, supplement kidney and quiet spirit, increase appetite./Spleen-kidney yang vacuity, vacuity and hypodynamia, inappetence, aching in lumbus and knees, insomnia and frequent dreaming.
TCMBANKHE007023 猫眼草 Phlegm-rheum cough asthma, edema, scrofula, scab and lichen, innominate toxin swelling.
TCMBANKHE005929 Radix et Rhizoma Notopterygii 羌活 To relieve pain and rheumatic conditions./Externally contracted wind-cold, headache without sweating, wind-cold-damp impediment, edema, toxin swelling of sores.
TCMBANKHE005337 Erica cinerea 灰色欧石楠
TCMBANKHE008794/XU-730 Euphorbia pekinensis 大蓟|大戟 陕西省安康市旬阳县 To drain water and expel rheum, dissipate binds and disperse swelling./Edema, seeper in chest and abdomen, phlegm-rheum, inhibited urine and stool, swollen welling abscess, scrofula.
TCMBANKHE003941/XU-730 Euphorbia pekinensis;Peking spurge root;Radix euphorbiae pekinensis|Euphorbia pekinensis 大蓟|大戟 陕西省安康市旬阳县 To drain water and expel rheum, dissipate binds and disperse swelling.;1. Treatment of edema of the face and the body, retention of fluid in the chest and ascites. Peking spurge root (Daji) is used with Jujube (Dazao), Kansui root (Gansui) and Genkwa flower (Yuanhua) in the formula Shizao Tang. 2. Treatment of boils, carbuncles, scrofula and subcutaneous nodules. Peking spurge root (Daji) is used with Pleione rhizome (Shancigu) and Moleplant seed (Qianjinzi) for internal and external use in the formula Zijin Ding./Edema, seeper in chest and abdomen, phlegm-rheum, inhibited urine and stool, swollen welling abscess, scrofula.;1. Treatment of edema of the face and the body, retention of fluid in the chest and ascites. Peking spurge root (Daji) is used with Jujube (Dazao), Kansui root (Gansui) and Genkwa flower (Yuanhua) in the formula Shizao Tang. 2. Treatment of boils, carbunc
TCMBANKHE004087/YEM-220 Fructus Quisqualis|Quisqualis indica L. 使君子 使君子 云南民族药物志:第二卷 To kill worms./Ascariasis, oxyuria disease, child gan accumulation. 阿昌族/傣族/德昂族/景颇族/傈僳族/普米族/佤族/瑶族
TCMBANKHE006781/YEM-333 Radix Saposhnikoviae divaricatae|Saposhnikovia divaricata (Turcz.)Schischk. 防风 防风 云南民族药物志:第二卷 To induce diaphoresis, to dispel wind, to alleviate rheumatic conditions, and to relieve spasm./Migraine, headache and generalized pain, common cold, rheumatoid arthritis, externally contracted wind-cold, wind-damp impediment pain, aching pain in joints, abdominal pain and diarrhea, intestinal wind bleeding, tetanus, wind papule itching, sores. 阿昌族/傣族/德昂族/景颇族/傈僳族
TCMBANKHE007964/YEM-607 Sarcandra glabra [Syn. Chloranthus glaber]|Sarcandra glabra(Thunb.)Nakai 九节茶|草珊瑚 九节茶 云南民族药物志:第三卷 To dispel wind and eliminate damp, quicken blood and dissipate stasis, clear heat and resolve toxin./Wind-damp impediment pain, numbness in limbs, knocks and falls, fracture, dysmenorrhea, postpartum blood stasis abdominal pain, pneumonia, acute appendicitis, bacillary dysentery, cholecystitis, abscess, stomatitis. 阿昌族/傣族/德昂族/哈尼族/景颇族/拉祜族/傈僳族/苗族/水族/瑶族/壮族
TCMBANKHE006570/YEM-68 Herba Artemisiae Annuae|Artemisia annua L. 青蒿|黄花蒿 黄花蒿 云南民族药物志:第一卷 To remove summer-heat, to relieve consumptive fever,and to stop malarial attacks./See Artemisia annua. 阿昌族/白族/傣族/德昂族/独龙族/景颇族/傈僳族/纳西族/怒族/瑶族/彝族/藏族/壮族
TCMBANKHE008476/YEM-68 Artemisia annua|Artemisia annua L. 黄花蒿 黄花蒿 云南民族药物志:第一卷 To clear heat, resolve summerheat, eliminate steam, interrupt malaria./Summerheat-heat, summerheat-damp, damp warmth, yin vacuity fever, malaria, jaundice. 阿昌族/白族/傣族/德昂族/独龙族/景颇族/傈僳族/纳西族/怒族/瑶族/彝族/藏族/壮族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000221 GRIA2 GLUR2; GLURB; GluA2; GluR-K2; HBGR2; gluR-2; gluR-B glutamate ionotropic receptor AMPA type subunit 2
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001755 MAOB - monoamine oxidase B
TCMBANKGE001818 NQO2 DHQV; DIA6; NMOR2; QR2 N-ribosyldihydronicotinamide:quinone reductase 2
TCMBANKGE004450 CA4 CAIV; Car4; RP17 carbonic anhydrase 4
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE007602 MMP7 MMP-7; MPSL1; PUMP-1 matrix metallopeptidase 7
TCMBANKGE008921 RXRA NR2B1 retinoid X receptor alpha
TCMBANKGE009758 PDE3A CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB phosphodiesterase 3A
TCMBANKGE014050 GABRA1 ECA4; EIEE19; EJM; EJM5 gamma-aminobutyric acid type A receptor subunit alpha1
TCMBANKGE014941 DPEP1 MBD1; MDP; RDP dipeptidase 1