Compound Summary


  Compound Information

药名:

swertiajaponin

别名:

2-(3,4-dihydroxyphenyl)-5-hydroxy-7-methoxy-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-tetrahydropyranyl]-4-chromenone; 2-(3,4-dihydroxyphenyl)-5-hydroxy-7-methoxy-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one; 4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5-hydroxy-7-methoxy-; Swertiajaponin; 2-(3,4-dihydroxyphenyl)-5-hydroxy-7-methoxy-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]chromen-4-one; C10187; 2-(3,4-dihydroxyphenyl)-5-hydroxy-7-methoxy-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]chromone; 6980-25-2;LMPK12111030; 6-beta-D-glucopyranosyl-3',4',5-trihydroxy-7-methoxyflavone; SCHEMBL4783740; Swertiajaponin; Leucanthoside;Leucanthoside;5,7,4'- trihydroxy- 6-methoxyflavone

分子式:

C22H22O11

Smiles:

COC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC(=C(C=C3)O)O)O)C4C(C(C(C(O4)CO)O)O)O

成分:

HBIN045180;HBIN011227;HBIN032989

OB_score:

32.115893

CAS_id:

6980-25-2

SymMap_id:

SMIT17833;SMIT05268

TCMID_id:

20489;41530

TCMSP_id:

MOL003137

PubChem_id:

44258368


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE002046 金果揽 See Tinospora sagittata .
TCMBANKHE003730 Gentiana scabra var. buesgeri 龙胆 Acute icterohepatitis, urinary tract infection, acute conjunctivitis, dribbling pain of urination, damp-heat jaundice, genital swelling and itch, damp-heat vaginal discharge, distended head and headache due to liver-gallbladder repletion fire, red eyes with gall, deafness, swelling in ear, pain in rib-side, bitter taste, fright wind and convulsion.
TCMBANKHE003782 Fructus Corni 山茱萸 To replenish the liver and kidney, restrain seminal discharge and relieve collapse./Dizziness and tinnitus, aching in lumbus and knees, impotence and emission, enuresis and frequent urination, flooding and spotting with vaginal discharge, vacuity and profuse sweating, vacuity desertion due to great sweating, diabetes mellitus due to internal heat, dysmenorrhea.
TCMBANKHE003804 Swertia pseudochinensis 獐牙菜 To drain fire and resolve toxin, disinhibit damp, fortify spleen./Acute icterohepatitis, chronic liver diseases, damp-heat jaundice, dysentery, gastritis, indigestion, acute conjunctivitis, toothache, mouth sore, swelling pain of sores.
TCMBANKHE003952 Folium Rhododendri Daurici 满山红 Acute bronchitis, chronic bronchitis.
TCMBANKHE004098 Herba Swertiae 青叶胆 To increase the flow of bile, and to remove heat and damp./Damp-heat jaundice, heat strangury with inhibited pain, damp-heat diarrhea dysentery, red and white vaginal discharge, influenza, malaria with fever, acute gastritis, acute pharyngolaryngitis, acute tonsillitis, acute conjunctivitis, allergic dermatitis.
TCMBANKHE005141 Gnetum gnemon 线轴买麻藤
TCMBANKHE006091 Swertia japonica 日本獐牙菜
TCMBANKHE007538 Achillea leptophylla 细叶蓍
TCMBANKHE007954 Flos Rhododendri Mollis 闹羊花 To relieve rheumatic conditions, and to eliminate blood stasis and alleviate pain./Tachycardia, palpitation, hypertension, wind-damp impediment pain, knocks and falls, intractable lichen.
TCMBANKHE006920 Iris sanguinea 豆豉草 To disperse accumulation and move water./Stomachache, abdominal pain.
TCMBANKHE009149 Swertia angustifolia 狭叶獐牙菜
TCMBANKHE007803 Herba Scutellariae barbatae 半枝莲 To remove toxic heat, and to cause diuresis./Heat toxin swollen welling abscess, throat pain, pulmonary welling abscess, intestinal welling abscess, scrofula, poisonous snake bite, knocks and falls, blood ejection, spontaneous external bleeding, blood strangury, edema, ascites, carcinoma.
TCMBANKHE007892/YNS-331 Swertia punicea|Swertia punicea Hemsl 紫红獐牙菜 紫红青叶胆 云南药材标准:第一册 清肝利胆,清热利湿。用于黄疸尿赤,热淋涩痛。|To clear liver and disinhibit gallbladder, clear heat and resolve toxin, disinhibit damp./Acute icterohepatitis, cholecystitis, wind-heat common cold, wind-fire toothache, swelling pain in throat, indigestion, acute bacillary dysentery, infection of urinary system, tinnitus and deafness, burns and scalds.
TCMBANKHE004162/YEM-17 Catharanthus roseus|Catharanthus roseus (L.) G.Don 长春花 长春花 云南民族药物志:第一卷 To resolve toxin, clear heat and calm liver, anticancer./Hypertension, swelling toxin of welling abscess and sore, scalds.
TCMBANKHE007630/YEM-983 Dipsacus asperoides|Dipsacus asperoides C.Y.Cheng et T.M.Ai 川续断 续断 云南民族药物志:第五卷 To supplement liver and kidney, strengthen sinews and bones, joint bones, check flooding and spotting./Limp aching lumbus and knees, wind-damp impediment pain, flooding and spotting, profuse menstruation, fetal bleeding, knocks and falls. 白族/布依族/傣族/德昂族/哈尼族/景颇族/拉祜族/傈僳族/苗族/纳西族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2