Compound Summary

  Compound Information

TCMBANKIN061444

药名:	Pedalitin
别名:	4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5,6-dihydroxy-7-methoxy-; FLAVONE, 3',4',5,6-TETRAHYDROXY-7-METHOXY-; 5,6,3',4'-Tetrahydroxy-7-methoxyflavone; BRN 1296526; 3',4',5,6-Tetrahydroxy-7-methoxyflavone; pedalitin; 2-(3,4-dihydroxyphenyl)-5,6-dihydroxy-7-methoxy-4-chromenone; 22384-63-0; 5-18-05-00543 (Beilstein Handbook Reference); C10119; 2-(3,4-dihydroxyphenyl)-5,6-dihydroxy-7-methoxychromen-4-one; 2-(3,4-dihydroxyphenyl)-5,6-dihydroxy-7-methoxy-chromen-4-one; 2-(3,4-dihydroxyphenyl)-5,6-dihydroxy-7-methoxy-chromone; 5,6,3',4'-tetrahydroxy-7-methoxyflavone
分子式:	C16H12O7
Smiles:	COC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC(=C(C=C3)O)O)O)O
成分:	HBIN039034;HBIN011083
OB_score:	34.019662
CAS_id:	22384-63-0
SymMap_id:	SMIT10929;SMIT19498
TCMID_id:	16746;32036
TCMSP_id:	MOL009847
PubChem_id:	31161

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE002319	Isodon japonica var. glaucocalyx	蓝萼香茶菜
TCMBANKHE003778	Lythrum salicaria	千屈菜			To clear heat and resolve toxin, promote contraction and stanch bleeding./Dysentery, diarrhea, hematochezia, flooding, ulcerating sores, blood ejection, spontaneous external bleeding, bleeding due to external injury.
TCMBANKHE007682	Sesamum indicum	胡麻叶			To boost qi, supplement brain and marrow, strengthen sinews and bones./Wind-cold-damp impediment, flooding, blood ejection, damp itchy in genitals.
TCMBANKHE004805	Rabdosia excisa	尾叶香茶菜
TCMBANKHE005099	Isodon rubescens var. lushiensis	卢氏冬凌草
TCMBANKHE005695	Isodon amethystoides;Plectranthus nummularius;Isodon shikokiana var. occidentalis;Isodon latifolia var. reniformis	香茶菜			Aerial parts: To clear heat and disinhibit damp, quicken blood and dissipate stasis, resolve toxin and disperse swelling; Root: To clear heat and resolve toxin, dispel stasis and relieve pain./Aerial parts: Damp-heat jaundice, strangury, edema, swelling pain in throat, impediment pain in joints, menstrual block, mammary welling abscess, hemorrhoids, effusion of back, knocks and falls, poisonous snake bite; Root: Poisonous snake bites, swelling toxin of sore and boil, aching sinews and bones, knocks and falls, burns and scalds.
TCMBANKHE006021	Semen Sesami Nigrum	黑芝麻			To tonify the liver and the kidney, to replenish vital essence and blood, and to relax the bowels./Dizziness, tinnitus and deafness, premature graying in beard and hair, hair loss during convalescence, intestinal dry and constipation.
TCMBANKHE008429	Lythrum anceps	日本千屈菜			See Lythrum salicaria ./See Lythrum salicaria .
TCMBANKHE008476/YEM-68	Artemisia annua|Artemisia annua L.	黄花蒿	黄花蒿	云南民族药物志：第一卷	To clear heat, resolve summerheat, eliminate steam, interrupt malaria./Summerheat-heat, summerheat-damp, damp warmth, yin vacuity fever, malaria, jaundice.	阿昌族/白族/傣族/德昂族/独龙族/景颇族/傈僳族/纳西族/怒族/瑶族/彝族/藏族/壮族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000286	GSK3B	-	glycogen synthase kinase 3 beta
TCMBANKGE000360	CCNA2	CCN1; CCNA	cyclin A2
TCMBANKGE000476	NCOA2	GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75	nuclear receptor coactivator 2
TCMBANKGE000701	ESR2	ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8	estrogen receptor 2
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000903	PTGS1	COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS	prostaglandin-endoperoxide synthase 1
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE000978	GCLM	GLCLR	glutamate-cysteine ligase modifier subunit
TCMBANKGE000994	AKR1B1	ADR; ALDR1; ALR2; AR	aldo-keto reductase family 1 member B
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001185	PPARG	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma	peroxisome proliferator activated receptor gamma
TCMBANKGE001202	MAPK14	CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA	mitogen-activated protein kinase 14
TCMBANKGE001581	AKR1C4	3-alpha-HSD; C11; CDR; CHDR; DD-4; DD4; HAKRA	aldo-keto reductase family 1 member C4
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE005198	AKR1E2	AKR1CL2; AKRDC1; LoopADR; TAKR; hTSP; htAKR	aldo-keto reductase family 1 member E2
TCMBANKGE006339	CA2	CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282	carbonic anhydrase 2
TCMBANKGE006907	AKR1A1	ALDR1; ALR; ARM; DD3; HEL-S-6	aldo-keto reductase family 1 member A1
TCMBANKGE008022	AKR1C3	DD3; DDX; HA1753; HAKRB; HAKRe; HSD17B5; PGFS; hluPGFS	aldo-keto reductase family 1 member C3
TCMBANKGE008077	AKR1C2	AKR1C-pseudo; BABP; DD; DD-2; DD/BABP; DD2; DDH2; HAKRD; HBAB; MCDR2; SRXY8; TDD	aldo-keto reductase family 1 member C2
TCMBANKGE009472	AKR1B10	AKR1B11; AKR1B12; ALDRLn; ARL-1; ARL1; HIS; HSI	aldo-keto reductase family 1 member B10
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1
TCMBANKGE013955	AKR1B15	AKR1B10L; AKR1B10L, AK1R1B7; AKR1R1B7	aldo-keto reductase family 1 member B15
TCMBANKGE014269	AKR1C1	2-ALPHA-HSD; 20-ALPHA-HSD; C9; DD1; DD1/DD2; DDH; DDH1; H-37; HAKRC; HBAB; MBAB	aldo-keto reductase family 1 member C1
TCMBANKGE014941	DPEP1	MBD1; MDP; RDP	dipeptidase 1
TCMBANKGE015062	AKR1D1	3o5bred; CBAS2; SRD5B1	aldo-keto reductase family 1 member D1