Compound Summary
Compound Information
药名: | cirsiliol |
别名: | 2-(3,4-dihydroxyphenyl)-5-hydroxy-6,7-dimethoxychromen-4-one; 6,7-Dimethoxy-5,3',4'-trihydroxyflavone; AKOS025287589; 3',4',5-trihydoxy-6,7-dimethoxyflavone; CTK8I3082; 3',4',5-Trihydroxy-6,7-dimethoxyflavone; ST50331608; LS-193892; BDBM50025321; DTXSID60187907; AC1L4N9W; 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5-hydroxy-6,7-dimethoxy-; 5,3'',4''-Trihydroxy-6,7-dimethoxyflavone; CHEMBL72637; AC1Q6AIE; 2-(3,4-dihydroxyphenyl)-5-hydroxy-6,7-dimethoxy-4H-1-benzopyran-4-one; 5,3',4'-trihydroxy-6,7-dimethoxyflavone; 34334-69-5; C10033; 2-(3,4-dihydroxyphenyl)-5-hydroxy-6,7-dimethoxy-chromone; ZINC4098510; MCULE-9854332110; 2-(3,4-Dihydroxy-phenyl)-5-hydroxy-6,7-dimethoxy-chromen-4-one; 2-(3,4-dihydroxyphenyl)-5-hydroxy-6,7-dimethoxy-4H-chromen-4-one; MFCD00210577; ST5331608; 2-(3,4-dihydroxyphenyl)-5-hydroxy-6,7-dimethoxy-4-chromenone; 2-(3,4-dihydroxyphenyl)-5-hydroxy-6,7-dimethoxy-chromen-4-one; MolPort-009-754-980; CHEBI:3719; FT-0620861; 6-methoxyluteolin 7-methyl ether; LMPK12111227; SCHEMBL1614677; Cirsiliol; 3',4',5-TRIHYDROXY-6,7-DIMETHOXY FLAVONE; 5,3′,4′-trihydroxy-6,7-dimethoxyflavone |
分子式: | C17H14O7 |
Smiles: | COC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC(=C(C=C3)O)O)O)OC |
成分: | HBIN010998; HBIN020718 |
SymMap_id: | SMIT01338;SMIT08847 |
TCMID_id: | 3743; 40728 |
TCMSP_id: | MOL007401 |
PubChem_id: | 160237 |
化合物对应的植物
| 植物ID | 拉丁名 | 药用植物名 | 药名 | 来源 | 功能与主治 | 使用民族 |
|---|
| TCMBANKHE002762 | Radix et Rhizoma Thalictri | 马尾莲 | Influenza, fever in children, common cold with fever, measles papules, malaria, damp-heat diarrhea dysentery, jaundice, red eyes with gall. | |||
| TCMBANKHE003004 | Achillea fragrantissima | |||||
| TCMBANKHE004166 | Cirsium chinense | 苦芺 | To clear heat and resolve toxin, cool blood and quicken blood./Vexation and oppression due to summerheat-heat, flooding and spotting, blood ejection from knocks and falls, hemorrhoids, clove sore. | |||
| TCMBANKHE004937 | Salvia officinalis | 药用丹参 | ||||
| TCMBANKHE008647 | Apis mellifera ligustica | 蜂胶 | To eliminate inflammation and relieve pain, moisten skin and engender flesh./Gastric ulcer, oral ulcer, cervical erosion, zoster, psoriasis, skin chap and pain, clavus, wound, carcinoma. | |||
| TCMBANKHE006376/YEM-362/XU-286 | Cirsium lineare|Cirsium lineare(Thunb.)Sch.-Bip. | 条叶蓟|滇小蓟|线叶蓟 | 条叶蓟 | 云南民族药物志：第二卷|陕西省安康市旬阳县 | To quicken blood and dissipate stasis, resolve toxin and disperse swelling./Menstrual disorder, amenorrhea, dysmenorrhea, mastitis, knocks and falls, urinary tract infection, welling abscess and boil, snake bite. | 佤族/瑶族 |
| TCMBANKHE006570/YEM-68 | Herba Artemisiae Annuae|Artemisia annua L. | 青蒿|黄花蒿 | 黄花蒿 | 云南民族药物志：第一卷 | To remove summer-heat, to relieve consumptive fever,and to stop malarial attacks./See Artemisia annua. | 阿昌族/白族/傣族/德昂族/独龙族/景颇族/傈僳族/纳西族/怒族/瑶族/彝族/藏族/壮族 |
| TCMBANKHE008476/YEM-68 | Artemisia annua|Artemisia annua L. | 黄花蒿 | 黄花蒿 | 云南民族药物志：第一卷 | To clear heat, resolve summerheat, eliminate steam, interrupt malaria./Summerheat-heat, summerheat-damp, damp warmth, yin vacuity fever, malaria, jaundice. | 阿昌族/白族/傣族/德昂族/独龙族/景颇族/傈僳族/纳西族/怒族/瑶族/彝族/藏族/壮族 |
| TCMBANKHE006261/YEM-689 | Rhizoma Phragmitis|Phragmites communis Trin. | 芦根|芦苇 | 芦苇 | 云南民族药物志：第四卷 | To remove heat, to promote the production of body fluid, to relieve emesis, and to alleviate dysuria./Febrile diseases with vexation and thirst, stomach heat vomiting, lung heat cough, pulmonary welling abscess, heat strangury with inhibited pain. | 阿昌族/傣族/德昂族/哈尼族/景颇族/拉祜族/傈僳族/水族/佤族/彝族/壮族 |
植物对应的疾病
| 疾病ID | 病名 | 疾病类型 | MeSH | 参考文献 |
|---|
化合物对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE000181 | PIM1 | PIM | Pim-1 proto-oncogene, serine/threonine kinase |
| TCMBANKGE000201 | ESR1 | ER; ESR; ESRA; ESTRR; Era; NR3A1 | estrogen receptor 1 |
| TCMBANKGE000205 | NOS2 | HEP-NOS; INOS; NOS; NOS2A | nitric oxide synthase 2 |
| TCMBANKGE000286 | GSK3B | - | glycogen synthase kinase 3 beta |
| TCMBANKGE000309 | SCN5A | CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 | sodium voltage-gated channel alpha subunit 5 |
| TCMBANKGE000360 | CCNA2 | CCN1; CCNA | cyclin A2 |
| TCMBANKGE000476 | NCOA2 | GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75 | nuclear receptor coactivator 2 |
| TCMBANKGE000478 | CHEK1 | CHK1 | checkpoint kinase 1 |
| TCMBANKGE000701 | ESR2 | ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 | estrogen receptor 2 |
| TCMBANKGE000749 | ALOX5 | 5-LO; 5-LOX; 5LPG; LOG5 | arachidonate 5-lipoxygenase |
| TCMBANKGE000813 | DPP4 | ADABP; ADCP2; CD26; DPPIV; TP103 | dipeptidyl peptidase 4 |
| TCMBANKGE000938 | CDK2 | CDKN2; p33(CDK2) | cyclin dependent kinase 2 |
| TCMBANKGE000978 | GCLM | GLCLR | glutamate-cysteine ligase modifier subunit |
| TCMBANKGE000994 | AKR1B1 | ADR; ALDR1; ALR2; AR | aldo-keto reductase family 1 member B |
| TCMBANKGE001041 | ALOX15 | 12-LOX; 15-LOX; 15-LOX-1; LOG15 | arachidonate 15-lipoxygenase |
| TCMBANKGE001073 | PTGS2 | COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 | prostaglandin-endoperoxide synthase 2 |
| TCMBANKGE001079 | CYP1A1 | AHH; AHRR; CP11; CYP1; CYPIA1; P1-450; P450-C; P450DX | cytochrome P450 family 1 subfamily A member 1 |
| TCMBANKGE001185 | PPARG | CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma | peroxisome proliferator activated receptor gamma |
| TCMBANKGE001202 | MAPK14 | CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA | mitogen-activated protein kinase 14 |
| TCMBANKGE001296 | ALOX12 | 12-LOX; 12S-LOX; LOG12 | arachidonate 12-lipoxygenase, 12S type |
| TCMBANKGE001581 | AKR1C4 | 3-alpha-HSD; C11; CDR; CHDR; DD-4; DD4; HAKRA | aldo-keto reductase family 1 member C4 |
| TCMBANKGE002727 | ALOXE3 | ARCI3; E-LOX; eLOX-3; eLOX3 | arachidonate lipoxygenase 3 |
| TCMBANKGE003643 | F7 | SPCA | coagulation factor VII |
| TCMBANKGE004266 | AR | AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM | androgen receptor |
| TCMBANKGE004437 | PYGM | GSD5 | glycogen phosphorylase, muscle associated |
| TCMBANKGE005198 | AKR1E2 | AKR1CL2; AKRDC1; LoopADR; TAKR; hTSP; htAKR | aldo-keto reductase family 1 member E2 |
| TCMBANKGE006339 | CA2 | CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 | carbonic anhydrase 2 |
| TCMBANKGE006907 | AKR1A1 | ALDR1; ALR; ARM; DD3; HEL-S-6 | aldo-keto reductase family 1 member A1 |
| TCMBANKGE008022 | AKR1C3 | DD3; DDX; HA1753; HAKRB; HAKRe; HSD17B5; PGFS; hluPGFS | aldo-keto reductase family 1 member C3 |
| TCMBANKGE008077 | AKR1C2 | AKR1C-pseudo; BABP; DD; DD-2; DD/BABP; DD2; DDH2; HAKRD; HBAB; MCDR2; SRXY8; TDD | aldo-keto reductase family 1 member C2 |
| TCMBANKGE009472 | AKR1B10 | AKR1B11; AKR1B12; ALDRLn; ARL-1; ARL1; HIS; HSI | aldo-keto reductase family 1 member B10 |
| TCMBANKGE010462 | ALOX12B | 12R-LOX; ARCI2 | arachidonate 12-lipoxygenase, 12R type |
| TCMBANKGE011079 | PRSS1 | TRP1; TRY1; TRY4; TRYP1 | serine protease 1 |
| TCMBANKGE013428 | ALOX15B | 15-LOX-2 | arachidonate 15-lipoxygenase type B |
| TCMBANKGE013955 | AKR1B15 | AKR1B10L; AKR1B10L, AK1R1B7; AKR1R1B7 | aldo-keto reductase family 1 member B15 |
| TCMBANKGE014269 | AKR1C1 | 2-ALPHA-HSD; 20-ALPHA-HSD; C9; DD1; DD1/DD2; DDH; DDH1; H-37; HAKRC; HBAB; MBAB | aldo-keto reductase family 1 member C1 |
| TCMBANKGE014941 | DPEP1 | MBD1; MDP; RDP | dipeptidase 1 |
| TCMBANKGE015062 | AKR1D1 | 3o5bred; CBAS2; SRD5B1 | aldo-keto reductase family 1 member D1 |
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