Compound Summary


  Compound Information

药名:

5,6,7,3,4-pentamethoxyflavone

别名:

Sinensetin; API0004181; Pedalitin permethyl ether; SR-05000002257-3; A816546; BC282855; KB-221448; 5,6,7,3',4'-Pentamethoxyflavone; 2-(3,4-dimethoxyphenyl)-5,6,7-trimethoxy-4-chromenone; Flavone, 5,6,7,3',4'-pentamethoxy; AKOS016009570; N2560; 240LNZ51AT; 2-(3,4-Dimethoxyphenyl)-5,6,7-trimethoxy-4H-chromen-4-one #; CS-5907; FT-0634191; DTXSID60177626; ST24039240; C10186; NCGC00163623-01; SR-05000002257; 3'',4'',5,6,7-pentamethoxy flavone; sinensetin; CCG-208419; CHEMBL226507; AN-50682; DB-046067; C-57750; 2-(3,4-dimethoxyphenyl)-5,6,7-trimethoxy-chromen-4-one; HY-N0297; 27181-91-5; 2-(3,4-Dimethoxyphenyl)-5,6,7-trimethoxy-4H-chromen-4-one; MEGxp0_000957; CHEBI:9159; CJ-24105; ZINC1531698; ST5331679; X1234; UNII-240LNZ51AT; SR-05000002257-2; BRD-K84996949-001-01-5; 2-(3,4-dimethoxyphenyl)-5,6,7-trimethoxy-4H-1-benzopyran-4-one; MolPort-001-741-112; 3',4',5,6,7-Pentamethoxyflavone; VA11761; BDBM50338975; AJ-26732; MFCD00017421; AK111262; 306S276; KB-221449; 2-(3,4-dimethoxyphenyl)-5,6,7-trimethoxy-1-benzopyran-4-one; LKMNXYDUQXAUCZ-UHFFFAOYSA-N; 2-(3,4-dimethoxyphenyl)-5,6,7-trimethoxychromen-4-one; 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-5,6,7-trimethoxy-; AC1L3RN3; 2306-27-6; 5,6,7,3'',4'' -pentamethoxyflavone; SCHEMBL621101; LMPK12111250; TR-010778; 2-(3,4-dimethoxyphenyl)-5,6,7-trimethoxy-chromone; CTK4F9237; ST50331679

分子式:

C20H20O7

Smiles:

COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)OC)OC)OC)OC

成分:

HBIN011092; HBIN044078

OB_score:

50.556849

CAS_id:

2306-27-6

SymMap_id:

SMIT04159;SMIT17720

TCMID_id:

40724; 19913

TCMSP_id:

MOL001803

PubChem_id:

145659


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000765 Chenopodium championii
TCMBANKHE001333 Semen Cucumis 甜瓜子
TCMBANKHE003373 Exocarpium Citri grandis 化橘红 To dispel cold, eliminate damp and phlegm, and arrest emesis or nausea./Treatment of cough, itching of the throat and profuse expectoration in colds, nausea, vomiting and epigastric distension caused by improper diet or excessive drinking.
TCMBANKHE004575 Citrus tankan 蕉柑 See Citrus chachiensis./See Citrus chachiensis .
TCMBANKHE007122 Fructus Aurantii Immaturus 枳实 To eliminate stagnation of qi, resolve phlegm and relieve stuffiness sensation in the chest and abdomen./Shock, indigestion, ptosis of anus or uterus, cardiac failure, distention fullness in chest and abdomen, phlegm aggregation.
TCMBANKHE005239 Fructus Aurantii 枳壳 To regulate the flow of qi, remove its stagnation, and alleviate distension;Treatment of distension and pain in the chest and hypochondriac regions due to stagnation of qi, indigestion with retention of phlegm and fluid, gastroptosis, prolapse of the rectum, prolapse of the uterus./Phlegm stagnation in chest and diaphragm, glomus in chest, distention in rib-side, food accumulation, retching counterflow.
TCMBANKHE005669 Pericarpium Citri Reticulatae Viride 青皮 To soothe the liver, to disintegrate stagnated qi, and to remove retained food./1. Its component limonene is an expectorant and antiasthmatic.2. Its decoction relaxes the smooth muscle of intestines, stomach, gallbladder and uterus.
TCMBANKHE008642 Murraya paniculata [Syn. Chalcas paniculata] 九里香 To move qi and quicken blood, dissipate stasis and relieve pain, resolve toxin and disperse swelling, anesthetize and settle pain./Pain in stomach duct, wind-damp impediment pain, painful swelling from knocks and falls, sore and welling abscess, snake or insect bites, local anesthesia.
TCMBANKHE005931 Citrus grandis var. tomentosa 化州柚 To dry damp and transform phlegm, rectify qi , disperse food./Wind-cold cough and asthma with abundant phlegm, vomiting and hiccough, non-digestion of food accumulation, distending pain in stomach duct and abdomen.
TCMBANKHE006736 Radix Smilacis 铁丝威灵仙
TCMBANKHE008364 Bauhinia championii 龙须藤 To dispel wind and eliminate damp, move qi and quicken blood./Wind-damp impediment pain, knocks and falls, pain in stomach duct, hemiplegia, gan accumulation, dysentery.
TCMBANKHE005457/YEM-144 Clerodendranthus spicatus|Clerodendranthus spicatus ( Thunb. )C.Y.Wu 猫须草|肾茶 肾茶 云南民族药物志:第一卷 To clear heat and dispel damp, expel stone and disinhibit water./Acute nephritis, chronic nephritis, cystitis, urethral stone, rheumatic arthritis. 阿昌族/傣族/德昂族/景颇族/傈僳族
TCMBANKHE008422/YNS-215/YEM-751/XU-85/XU-86/XU-593 Ageratum conyzoides|Ageratum conyzoides L.|Ageratum conyzoides L. 胜红蓟|藿香蓟 胜红蓟 云南药材标准:第六册|云南民族药物志:第四卷|广东省廉江市石岭镇 疏风清热,解毒止痒,止血。用于感冒发热,喉咙肿痛,疮疖,湿疹,崩漏。|To clear heat and resolve toxin, stanch bleeding, relieve pain./Common cold with fever, swelling pain in throat, hemoptysis, spontaneous external bleeding, flooding and spotting, pain in stomach duct and abdomen, wind-damp impediment pain, knocks and falls, bleeding due to external injury, swelling toxin of welling abscess and sore, eczema titillation. 傣族/德昂族/哈尼族/基诺族/景颇族/傈僳族/佤族/瑶族/彝族/壮族
TCMBANKHE005584/YEM-890 Citrus reticulata|Citrus reticulata Blanco 橘皮|橘 云南民族药物志:第五卷 To rectify qi and downbear counterflow, regulate center and increase appetite, dry damp and transform phlegm./Spleen-stomach qi stagnation and damp obstruction, lung qi block, cough with profuse phlegm, mammary welling abscess, indigestion, vomiting. 阿昌族/傣族/德昂族/基诺族/景颇族/傈僳族/水族/瑶族/彝族
TCMBANKHE008726/YEM-890 Citrus reticulata|Citrus reticulata Blanco 橘皮(陈皮)|橘 云南民族药物志:第五卷 To rectify qi and downbear counterflow, regulate center and increase appetite, dry damp and transform phlegm./Spleen-stomach qi stagnation and damp obstruction, lung qi block, cough with profuse phlegm, mammary welling abscess, indigestion, vomiting. 阿昌族/傣族/德昂族/基诺族/景颇族/傈僳族/水族/瑶族/彝族
TCMBANKHE004276/YEM-974 Citrus sinensis|Citrus sinensis(L.)Osbeck 甜橙 黄果树 云南民族药物志:第五卷 To move qi, precipitate qi, relieve pain, disperse distention, free milk./Galactostasis. 布依族/水族/佤族/彝族/壮族
TCMBANKHE005203/YEM-999/XU-341 Radix Isatidis seu Baphicacanthi|Isatis indigotica Fort.|Isatis indigotica 板蓝根|菘蓝 板蓝根 云南民族药物志:第五卷|山东省菏泽市 To remove toxic heat, to reduce heat in blood, and to soothe sore throat./Epidemic encephalitis, measles papulis, parotitis, influenza, warm toxin macular eruption, ardent fever with headache, massive head scourge, throat pain, maculopapular eruption, epidemic parotitis, erysipelas, hepatitis, swelling toxin of sore and welling abscess. 回族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000121 KCNH2 ERG-1; ERG1; H-ERG; HERG; HERG1; Kv11.1; LQT2; SQT1 potassium voltage-gated channel subfamily H member 2
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000264 ABCB1 ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1 ATP binding cassette subfamily B member 1
TCMBANKGE000309 SCN5A CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 sodium voltage-gated channel alpha subunit 5
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000474 NCOA1 F-SRC-1; KAT13A; RIP160; SRC1; bHLHe42; bHLHe74 nuclear receptor coactivator 1
TCMBANKGE000476 NCOA2 GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75 nuclear receptor coactivator 2
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000633 ADRB2 ADRB2R; ADRBR; B2AR; BAR; BETA2AR adrenoceptor beta 2
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000766 ACHE ACEE; ARACHE; N-ACHE; YT acetylcholinesterase (Cartwright blood group)
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000877 ABCG2 ABC15; ABCP; BCRP; BCRP1; BMDP; CD338; CDw338; EST157481; GOUT1; MRX; MXR; MXR-1; MXR1; UAQTL1 ATP binding cassette subfamily G member 2 (Junior blood group)
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001506 ADRA1B ADRA1; ALPHA1BAR adrenoceptor alpha 1B
TCMBANKGE003643 F7 SPCA coagulation factor VII
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1