Compound Summary

  Compound Information

TCMBANKIN061496

药名:	calycosin
别名:	HSDB 8109; 7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)chromen-4-one; CHEBI:17793; 7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one; 09N3E8P7TA; calycosin (OLD); 20575-57-9; HY-N0519; ZINC6018563; 7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)-1-benzopyran-4-one; 3'-hydroxy-formononetin; calycosin ; LMPK12050056; MEGxp0_001325; BRD-K05039497-001-01-6; 7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one; 3',7-dihydroxy-4'-methoxy-isoflavone; AKOS015896719; UNII-09N3E8P7TA; 4H-1-Benzopyran-4-one, 7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)-; 3', 7-dihydroxy-4'-methoxyisoflavone; 575C579; C01562; HMS2268B05; C-17889; MolPort-001-741-659; Calycosin; X1103; SCHEMBL73013; Q-100254; AC1NQX1G; 7-hydroxy-3-(3-hydroxy-4-methoxy-phenyl)chromen-4-one; 7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)-4-chromenone; 7-hydroxy-3-(3-hydroxy-4-methoxy-phenyl)chromone; CHEMBL241608; CS-3715; ZZAJQOPSWWVMBI-UHFFFAOYSA-N; BG01576591; MLS000876988; DTXSID70174580; 3',7-dihydroxy-4'-methoxyisoflavone; ACon1_000650; I07-0176; NP-004576; NCGC00169494-01; 3-(4-methoxy-3-oxidanyl-phenyl)-7-oxidanyl-chromen-4-one; MCULE-7559555984; 7,3'-dihydroxy-4'-methoxyisoflavone; A814711; N1412; 3'-hydroxyformononetin; FT-0630465; MFCD00210598; SMR000440659; AN-8397; AC-8043; 3',7-dihydroxy-4'-methoxy-isoflavone
分子式:	C16H12O5
Smiles:	COC1=C(C=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)O)O
成分:	HBIN019425;HBIN007776
OB_score:	50.702573
CAS_id:	67492-31-3
SymMap_id:	SMIT01316;SMIT03025;SMIT12030
TCMID_id:	3004
TCMSP_id:	MOL000417;MOL011078
PubChem_id:	5280448

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE000437	Erycibe expansa
TCMBANKHE000999		红芪			to promote the drainage of pus and the growth of new tissue.
TCMBANKHE001046		胡芦巴			Hyperlipemia, kidney vacuity cold, cold pain in lesser-abdomen, mounting qi , beriberi.
TCMBANKHE001634	Fructus Choerospondiatis	广枣			To promote the flow of qi and blood, to replenish the heart and allay excitement./Treatment of stagnation of qi and blood with pectoral pain, palpitation and shortness of breath, uneasiness in mind.
TCMBANKHE004897	Piptanthus nanus	小沙冬青			See Ammopiptanthus mongolicus./See Ammopiptanthus mongolicus.
TCMBANKHE003728	Radix Glycyrrhizae	甘草			To reinforce the function of the spleen and replenish qi, to remove heat and counteract toxicity, to dispel phlegm and relieve cough, to alleviate spasmodic pain, and to moderate drug actions./1. Its decoction can inhibit intestinal smooth muscles of rabbins in vitro, but glycyrrhizin and glycyrrhetinic acid have no this effect.2. Possessing an adrenocorticomimetic effect.3. Its extract and glycyrrhizin exerts a detoxifying effect.4. Antitussive and antiasthmatic. 5. Glycyrrhizin has anti-inflammatory effect similar to hydrocortisone.
TCMBANKHE003743	Radix Astragali	黄芪			To reinoforce qi and invigorate the function of the spleen./Common cold, influenza, chronic wound ulcer, chronic glomerulonephritis, diabetes mellitus due to internal heat, qi vacuity edema, chronic gastritis, qi vacuity and hypodynamia, reduced food intake and sloppy stool, center qi fall, chronic diarrhea, prolapse of rectum, hematochezia, flooding and spotting, spontaneous sweating due to exterior vacuity.
TCMBANKHE005218	Andira inermis	无刺柯桠树
TCMBANKHE007396	Flos Eriocauli	谷精草			To expel wind and heat and to clear the eye of corneal opacity./Distended red eyes and screen, delacrimation and photophobia, night blindness, headache, deep-source nasal congestion, throat impediment, toothache, wind papule itching.
TCMBANKHE005692	Erythrina crysragalli;Erythrina latissima	鸡冠刺桐
TCMBANKHE006212	Semen Astragali Complanati;Semen Astragali Complati	潼蒺藜;沙苑子			Treatment of back pain, nocturnal emission and premature ejaculation in deficiency syndromes of the kidney, turbid discharge with urination, excessive leukorrhea, dribbling of urine after urination, dizziness and blurred vision,to benefit the liver./Treatment of back pain, nocturnal emission and premature ejaculation in deficiency syndromes of the kidney, turbid discharge with urination, excessive leukorrhea, dribbling of urine after urination, dizziness and blurred vision.
TCMBANKHE008538		土荆皮			Scab and lichen, eczema, neurodermatitis .
TCMBANKHE009076	Sophora moorcroftiana	砂生槐			To clear heat and dry damp, resolve toxin./Damp-heat jaundice, diphtheria, nipple moth.
TCMBANKHE008040	Astragalus mongholicus	蒙古黄芪			See Astragalus membranaceus./See Astragalus membranaceus.
TCMBANKHE008647	Apis mellifera ligustica	蜂胶			To eliminate inflammation and relieve pain, moisten skin and engender flesh./Gastric ulcer, oral ulcer, cervical erosion, zoster, psoriasis, skin chap and pain, clavus, wound, carcinoma.
TCMBANKHE008315	Cortex erythrie	海桐皮			1. To dispel wind and dampness; 2. To clear the meridians/Wind-damp impediment, pain in lumbus and knees, scab sore, lichen, eczema.
TCMBANKHE007797	Sophora moorcroftiana	沙身槐;砂生槐			To clear heat and dry damp, resolve toxin./Damp-heat jaundice, diphtheria, nipple moth.
TCMBANKHE007847	Caulis Millettiae; Caulis spatholobi	鸡血藤			To enrich the blood, to activate blood circulation, and to remove obstruction of the channels and collaterals./Treatment of menstrual disorders, anemia, numbness and paralysis, rheumatic arthralgia.
TCMBANKHE003875/YEM-397	Millettia dielsiana|Millettia dielsiana Harms	昆明鸡血藤	鸡血藤	云南民族药物志：第二卷	To supplement blood and stanch bleeding, quicken blood and free network vessels./Blood vacuity and general weakness, taxation damage and sinew bone pain, menstrual disorder, amenorrhea, postpartum abdominal pain, persistent flow of lochia, wind-damp impediment pain, bleeding, knocks and falls.	普米族/瑶族/彝族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

TCMBANKDI000085

Inflammation

phenotype

Pathological Conditions, Signs and Symptoms

27678042

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000046	PIK3R1	AGM7; GRB1; IMD36; p85; p85-ALPHA	phosphoinositide-3-kinase regulatory subunit 1
TCMBANKGE000047	AKT1	AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA	AKT serine/threonine kinase 1
TCMBANKGE000051	IL1B	IL-1; IL1-BETA; IL1F2; IL1beta	interleukin 1 beta
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000204	CXCL8	GCP-1; GCP1; IL8; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1; SCYB8	C-X-C motif chemokine ligand 8
TCMBANKGE000223	KEAP1	INrf2; KLHL19	kelch like ECH associated protein 1
TCMBANKGE000265	SQSTM1	A170; DMRV; FTDALS3; NADGP; OSIL; PDB3; ZIP3; p60; p62; p62B	sequestosome 1
TCMBANKGE000290	NQO1	DHQU; DIA4; DTD; NMOR1; NMORI; QR1	NAD(P)H quinone dehydrogenase 1
TCMBANKGE000305	PIK3CD	APDS; IMD14; P110DELTA; PI3K; p110D	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
TCMBANKGE000306	PIK3CG	PI3CG; PI3K; PI3Kgamma; PIK3; p110gamma; p120-PI3K	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
TCMBANKGE000307	PIK3CB	P110BETA; PI3K; PI3KBETA; PIK3C1	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
TCMBANKGE000308	PIK3CA	CLAPO; CLOVE; CWS5; MCAP; MCM; MCMTC; PI3K; PI3K-alpha; p110-alpha	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
TCMBANKGE000330	HMOX1	HMOX1D; HO-1; HSP32; bK286B10	heme oxygenase 1
TCMBANKGE000516	IL25	IL17E	interleukin 25
TCMBANKGE000517	WDR7	TRAG	WD repeat domain 7
TCMBANKGE000518	GPER1	CEPR; CMKRL2; DRY12; FEG-1; GPCR-Br; GPER; GPR30; LERGU; LERGU2; LyGPR; mER	G protein-coupled estrogen receptor 1
TCMBANKGE000519	BATF2	SARI	basic leucine zipper ATF-like transcription factor 2
TCMBANKGE000752	Il33	9230117N10Rik; Il-33; Il1f11; NF-HEV	interleukin 33
TCMBANKGE000823	GABPA	E4TF1-60; E4TF1A; NFT2; NRF2; NRF2A; RCH04A07	GA binding protein transcription factor subunit alpha
TCMBANKGE000882	SERPINE1	PAI; PAI-1; PAI1; PLANH1	serpin family E member 1
TCMBANKGE000925	PCNA	ATLD2	proliferating cell nuclear antigen
TCMBANKGE000990	EGFR	ERBB; ERBB1; HER1; NISBD2; PIG61; mENA	epidermal growth factor receptor
TCMBANKGE001114	IL6	BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6	interleukin 6
TCMBANKGE001126	NFE2L2	HEBP1; IMDDHH; NRF2; Nrf-2	nuclear factor, erythroid 2 like 2
TCMBANKGE001132	BAX	BCL2L4	BCL2 associated X, apoptosis regulator
TCMBANKGE001171	SRC	ASV; SRC1; THC6; c-SRC; p60-Src	SRC proto-oncogene, non-receptor tyrosine kinase
TCMBANKGE001178	STAT3	ADMIO; ADMIO1; APRF; HIES	signal transducer and activator of transcription 3
TCMBANKGE001181	TGFB1	CED; DPD1; IBDIMDE; LAP; TGF-beta1; TGFB; TGFbeta	transforming growth factor beta 1
TCMBANKGE001201	MAPK3	ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; p44-ERK1; p44-MAPK	mitogen-activated protein kinase 3
TCMBANKGE001203	MAPK1	ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK	mitogen-activated protein kinase 1