Compound Summary


  Compound Information

药名:

Scutevulin

别名:

80713-32-2; 2',5,7-Trihydroxy-8-methoxyflavone; SCHEMBL5162875; 5,7-dihydroxy-2-(2-hydroxyphenyl)-8-methoxy-chromen-4-one; scutevulin; CHEMBL2235250; 5,7-dihydroxy-2-(2-hydroxyphenyl)-8-methoxy-4-chromenone; 5,7,2'-trihydroxy-8-methoxyflavone; 5,7-dihydroxy-2-(2-hydroxyphenyl)-8-methoxychromen-4-one; LMPK12111303; AC1NT0AX; 5,7-dihydroxy-2-(2-hydroxyphenyl)-8-methoxy-chromone

分子式:

C16H12O6

Smiles:

COC1=C(C=C(C2=C1OC(=CC2=O)C3=CC=CC=C3O)O)O

成分:

HBIN043536;HBIN043535

OB_score:

20.673785

CAS_id:

80713-32-2

SymMap_id:

SMIT13042;SMIT17635

TCMID_id:

19573;33253

TCMSP_id:

MOL012267

PubChem_id:

5321205


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE003734 radix tripterygii wilfordii 雷公藤 To expel wind-dampness, relieve swelling, alleviate pain and dredge the meridian passage./Rheumatoid arthritis, rheumatic arthritis, glomerulonephritis, nephropathy syndrome, erythematous lupus, dryness in eyes and mouth, Behcet’s syndrome, psoriasis, eczema, leprosy, scab sore, intractable lichen.
TCMBANKHE003746 Radix Scutellariae 黄芩 To remove damp-heat, to quench fire and counteract toxicity, to arrest bleeding, and to prevent abortion./Chest oppression with retching, diarrhea, jaundice, lung heat cough, infection of upper respiratory tract, acute tonsillitis, acute pharyngolaryngitis, ardent fever with vexation and thirst, blood heat, blood ejection, spontaneous external bleeding, swelling toxin of welling abscess and sore, stirring fetus in pregnancy.
TCMBANKHE003805 Sorbaria sorbifolia 珍珠梅 To quicken blood and dispel stasis, disperse swelling and relieve pain./Fracture, knocks and falls, wind-damp impediment pain.
TCMBANKHE004259 Plantago major 大车前 See Plantago asiatica./See Plantago asiatica.
TCMBANKHE004516 Sorbaria arborea 高丛珍珠梅 See Sorbaria sorbifolia ./See Sorbaria sorbifolia .
TCMBANKHE008975 Bulbus Lilii 百合 To nourish yin and moisten the lung, and to tranquilize the mind./Yin vacuity enduring cough, phlegm containing blood, fright palpitation and vacuity vexation, insomnia and frequent dreaming, trance.
TCMBANKHE006246 Scutellaria altissima 高黄芩
TCMBANKHE006914 Ramulus Euonymi 鬼箭羽 For activating blood and modulating period/Concretion and conglomeration, pain in heart and abdomen, amenorrhea, dysmenorrhea, postpartum stasis stagnation abdominal pain, retention of lochia, mounting qi , joint running impediment pain, swelling of sores, painful wound from knocks and falls, burns and scalds, poisonous snake bite.
TCMBANKHE007163 Bulbus Lilii 百合 To nourish yin and moisten the lung, and to tranquilize the mind./Yin vacuity enduring cough, phlegm containing blood, fright palpitation and vacuity vexation, insomnia and frequent dreaming, trance.
TCMBANKHE008359 Semen Oroxyli 木蝴蝶 To remove heat from the lung and relieve sore throat, and to regulate the flow of qi of the liver and the stomach./Lung heat cough, throat impediment, aphonia, liver stomach qi pain.
TCMBANKHE007803 Herba Scutellariae barbatae 半枝莲 To remove toxic heat, and to cause diuresis./Heat toxin swollen welling abscess, throat pain, pulmonary welling abscess, intestinal welling abscess, scrofula, poisonous snake bite, knocks and falls, blood ejection, spontaneous external bleeding, blood strangury, edema, ascites, carcinoma.
TCMBANKHE008042 Clerodendron fragrans 臭茉莉 To dispel wind and eliminate damp, quicken blood and disperse swelling./Wind-damp bone pain, beriberi, edema, hemorrhoids, prolapse of rectum, itchy papules, scab sore, chronic medullitis.
TCMBANKHE005300/YEM-502/XU-414/XU-629/XU-653 Perilla frutescens var. acuta [Syn. Perilla frutescens var. purpurascens ]|Perilla frutescens(L.)Britt.|Perilla frutescens var. crispa 尖紫苏叶|紫苏|回回苏 紫苏 云南民族药物志:第三卷|湖北省宜昌市夷陵区 See Perilla frutescens var. arguta ./See Perilla frutescens var. arguta . 傣族/回族/哈尼族/傈僳族/苗族/水族/佤族/瑶族/彝族/壮族
TCMBANKHE003745/YEM-786/XU-131/XU-268/XU-643 Erigeron breviscapus|Erigeron breviscapus(Vant.)Hand.-Mazz.|Erigeron breviscapus (Vant.) Hand. -Mazz. 灯盏细辛|短葶飞蓬|短葶飞蓬(灯盏花) 灯盏花 云南民族药物志:第四卷|云南省迪庆州维西县 To dissipate cold and resolve exterior, dispel wind and eliminate damp, quicken network vessels and relieve pain, disperse accumulation./Common cold with headache and nasal congestion, wind-damp impediment pain, paralysis, acute gastritis, child gan accumulation, knocks and falls. 阿昌族/白族/傣族/德昂族/基诺族/傈僳族/苗族/彝族/藏族/壮族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE004437 PYGM GSD5 glycogen phosphorylase, muscle associated
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1
TCMBANKGE014941 DPEP1 MBD1; MDP; RDP dipeptidase 1