Compound Summary


  Compound Information

药名:

6,7-dimethoxycoumarin

别名:

6, 7-dimethoxycoumarin; 6, 7-dimethoxy coumarin; 6,7-dimethoxy-coumarin; 6, 7- dimethoxycoumarin; 6,7-Dimethoxy coumarin;6,7-dimethoxy-2h-1-benzopyran-2-one;C-10265; EINECS 204-369-0; 6,7-Dimethoxy-Benzopyran-2-one; Dimethyl esculetin; KS-00000W5Q; W-1779; C11H10O4; 6,7-Dimethoxy-Coumarin; AC1L1QYE; DTXSID10152640; ZINC00002067; 6,7-DIMETHOXYCOUMARIN; Esculetin 6,7-dimethyl ether; 6,7-Dimethoxycoumarine; RTR-003340; ST50319943; CJ-00079; BRN 0169572; TR-003340; Scoparin?; Escoparone; 6,7-dimethoxy-2-chromenone; Bio-0192; 6,7-Dimethoxy-2-benzopyrone; 6,7-Dimethoxy-chromen-2-one; BDBM50361374; CC-22351; 2H-1-Benzopyran-2-one,6,7-dimethoxy-; 2H-1-Benzopyran-2-one, 6,7-dimethoxy-; AKOS000277541; AB3000014; 6,7-Dimethoxybenzopyran-2-one; 6,7-Dimethoxy-2H-chromen-2-one #; OR345015; ACon1_002079; SR-01000631300-1; 6,7-Dimethoxy-2H-chromen-2-one; ST5319943; AN-43331; GUAFOGOEJLSQBT-UHFFFAOYSA-N; Scoparone; KSC241M7T; o,o-Dimethylesculetin; 5-18-03-00204 (Beilstein Handbook Reference); BRD-K16835051-001-02-0; Benzopyran-2-one, 6,7-dimethoxy-; SC-46088; PubChem13307; 120S081; 6,7-dimethoxychromen-2-one; H5841PDT4Y; C09311; 254886_ALDRICH; FT-0603321; MEGxp0_001422; Esculetin dimethyl ether; 6,7-Dimethylcoumarine; Scoparon; CHEMBL325864; AM20020282; CCG-41207; 120-08-1; IN1101; LS-55182; Dimethylaesculetin; I14-17932; Maybridge4_003009; SCHEMBL240777; AIDS026315; o-Methylisoscopoletin; Benzopyran-2-one, 6,7-dimethoxy- (9CI); MCULE-1591753422; ZB000476; N2328; AC-11197; Aesculetin dimethyl ether; Coumarin, 6,7-dimethoxy-; 6,7-Dimethylesculetin; 6,7-Dimethoxy-2H-1-benzopyran-2-one; Q-100099; CHEBI:9055; 6,7-dimethoxycoumarin; ZINC2067; BRD-K16835051-001-01-2; MolPort-000-881-854; MFCD00006871; UNII-H5841PDT4Y; HMS1529I17; AB0019685; Scopoletin methyl ether; ACMC-20am0m; scoparone ; AIDS-026315; o-Methylscopoletin; 6,7-Dimethoxycoumarin, 98%;scoparone

分子式:

C11H10O4

Smiles:

COC1=C(C=C2C(=C1)C=CC(=O)O2)OC

成分:

HBIN012080

OB_score:

74.754958

CAS_id:

120-08-1

SymMap_id:

SMIT02466;SMIT00135

TCMID_id:

40407;41181;24253;41944;6202;19525

TCMSP_id:

MOL001999

PubChem_id:

8417


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000263 印度橘
TCMBANKHE000516 Herba Sarcatidrae 肿节风 1. Inhibiting the growth of Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella typhosa and various Shigella dysenteriae in vitro. 2. Nonspecfic anti-inflammatory and promoting the repair of gastric ulcer. 3. Its volatile oil and flavones inhibit sa/1. To clear heat and toxic material. For carbuncle due to intensive heat, aphthae, gingivitis, dysentery, filariasis, etc. 2. To promote blood circulation and remove blood stasis, expel wind and dredge channels. For trauma, rheumatism, stomachache. Recent
TCMBANKHE000956 flos puerariae lobatae 葛花 To relieve fever, to promote the production of body fluid,to facilitate eruption, and to arrest diarrhea./Treatment of fever, headache and stiffness of th nape in exogenous affections, thirst, diabetes, measles with inadequate eruption, acute dysentery or diarrhea, stiff and painful nape in hypertension.
TCMBANKHE003438 Gentiana kuroo 酷睿龙胆
TCMBANKHE003749 Radix Puerariae 葛根 To relieve fever, to promote the production of body fluid,to facilitate eruption, and to arrest diarrhea./Angina pectoris, hypertension, headache due to externally contracted wind-heat, rigidity of neck, thirst, diabetes mellitus, non-eruption of measles, heat dysentery, diarrhea, deafness in early stage, optic nerve atrophy, retinitis.
TCMBANKHE003782 Fructus Corni 山茱萸 To replenish the liver and kidney, restrain seminal discharge and relieve collapse./Dizziness and tinnitus, aching in lumbus and knees, impotence and emission, enuresis and frequent urination, flooding and spotting with vaginal discharge, vacuity and profuse sweating, vacuity desertion due to great sweating, diabetes mellitus due to internal heat, dysmenorrhea.
TCMBANKHE003799 Fructus Forsythiae 连翘 To remove toxic heat, to cause subsidence of sweeling,and to eliminate modulation./Influenza in early stage, common cold in early stage, wind-heat common cold, encephalitis, hepatitis, tuberculosis, warm disease, heat strangury with inhibited pain, welling abscess, welling abscess and flat abscess, toxin swelling, scrofula, goiter and tuberculosis, throat impediment.
TCMBANKHE004172 Radix Bupleuri 柴胡 To relieve fever, to soothe the liver, and to cure drooping and ptosis./Common cold, influenza, malaria, acute pancreatitis, pleuritis, neuritis, gastritis, acute cholecystitis, hepatitis, fever due to external contraction, keratitis, cold-heat in turn, liver depression and rib-side pain, mammary distention, dizziness and headache, menstrual disorder, prolapse of rectum due to qi vacuity fall, prolapse of uterus, gastroptosis.
TCMBANKHE005942 Dendrobium thyrsiflorum 菊花石斛
TCMBANKHE008098 Radix Curcumae 郁金 1. To invigorate blood and stop pain; 2. To promote qi circulation and release stagnation; 3. To cool blood and clear heat in the heart; 4. To relieve jaundice and facilitate gall bladder function/See Curcuma longa.
TCMBANKHE004494 Rubia wallichiana 广金钱草 See Rubia cordifolia ./See Rubia cordifolia.
TCMBANKHE008447 Zanthoxylum simulans 野花椒叶 To dispel wind and dissipate cold, fortify stomach and expel worms, dispel damp and check diarrhea, quicken blood and free menstruation./Knocks and falls, wind-damp pain, pain of blood stasis, amenorrhea, hemoptysis, blood ejection, pain wind in joints.
TCMBANKHE006366 Radix Moghaniae Philippinensis 千斤拔
TCMBANKHE004699 fructus hippophae 沙棘
TCMBANKHE004859 鼠曲草 Cough with profuse phlegm, asthma, wind-cold common cold, pain in sinews and bones, vaginal discharge, welling abscess and open sore.
TCMBANKHE005024 Liriodendron tulipifera 北美鹅掌楸 To dispel wind and eliminate damp, dissipate cold and relieve cough./Wind-damp impediment pain, wind-cold cough.
TCMBANKHE007973 Herba Artemisiae Scopariae 茵陈 To remove damp-heat and relieve jaundice./1. Its decoction or its volatile oil, and active components such as chlorogenic acid, caffeic acid and hydroxyacetophenone are chologogues.2. Protecting the liver of experimental animals from the damage of CCl4.3. Decreasing the level of blood lipids and alleviating artherosclerosis and lipidosis in rabbits.4. Increasing the coronary flow of rabbits in vitro.5. Its volatile oil inhibits the growth of Shigella dysenteriae, Hemolytic streptococcus and various dermatomyces in vitro.6. Anticoagulative.
TCMBANKHE005954 Radix Pulsatillae 白头翁 1. To clear heat and release toxins; 2. To cool the blood and stop dysentery/Amebic dysentery, nosebleed, flooding and spotting, bleeding from hemorrhoids, cold-heat warm malaria, vaginal discharge, pudendal itch, eczema, scrofula, welling abscess, painful red eyes, neurodermatitis.
TCMBANKHE008791 Duranta repens 假连翘 To quicken blood and relieve pain, interrupt malaria./Malaria, painful wound from knocks and falls.
TCMBANKHE008092 Radix Cyathulae 川牛膝 To eliminate blood stasis and stimulate menstrual discharge, to allay arthralgia and ease the joint, and to relieve urinary disturbance./Amenorrhea with concretion and conglomeration, retention of placenta, impediment pain in joints, hematuria, blood strangury, knocks and falls.
TCMBANKHE006055 Herba Potentillae Chinensis 委陵菜 To remove toxic heat and reduce heat in blood, and to relieve dysentery./Red dysentery and abdominal pain, enduring dysentery, bleeding hemorrhoids, swelling toxin of sore and welling abscess.
TCMBANKHE006144 Dendrobium capillipes 短棒石斛
TCMBANKHE006232 Fructus Citri sarcodactylis 佛手 To regulate the qi of the liver and stomach, and relieve pain./Stomachache, distention in rib-side, vomiting, dysphagia-occlusion, phlegm-rheum cough asthma.
TCMBANKHE009177 青果 Swelling pain in throat, cough, vexation and thirst, poisoning of fish or crab.
TCMBANKHE009079 Phellodendron japonicum 日本黄柏
TCMBANKHE006697 Aralia fargesii 龙眼独活 See Aralia cordata ./See Aralia cordata.
TCMBANKHE008915 Dendrobium aurantiacum var. denneanum 叠鞘石斛 See Dendrobium nobile./See Dendrobium nobile.
TCMBANKHE007097 Bupleurum fruticescens 木柴胡
TCMBANKHE007098 Fructus Gardeniae 栀子;生山栀 1. To clear heat and reduce fire; 2. To cool blood and release toxins; 3. To eliminate dampness;4.Treatment of febrile diseases with restlessness, jaundice with dark urine, hematuria with difficult painful urination, hemoptysis and epistaxis caused by heat in the blood, inflammation of the eye, boils and sores, external use for sprains and bruises.Fructus Gardeniae (charred): Hemoptysis, epistaxis, hematuria and abnormal uterine bleeding caused by heat in the blood./Acute icterohepatitis, febrile diseases, vexation, melancholia, restlessness, stagnation of damp-heat in liver and gall, fever, jaundice, short voidings of reddish urine, blood ejection, spontaneous external bleeding, dysentery with hematochezia and hematuria.1. The active components such as crocin, crocetin, genipin, or alcoholic extract protect the liver from carbon tetrachloride and increasing biliary secretion. Oral use of its decoction induce gallbladder contraction.2. Oral or intraperitoneal use of its decoction and alcoholic extract exerts a sustained hypotensive effect in anaesthetized and un-anaesthetized animals.3. Hemostatic.
TCMBANKHE007285 Hibiscus taiwanensis 台湾芙蓉 To clear lung and relieve cough, cool blood and resolve toxin./Lung heat cough, toxin swelling of sores.
TCMBANKHE005587/XU-18 Zanthoxylum schinifolium|Zanthoxylum schinifolium Sieb. et Zucc 青椒|青花椒 云南省楚雄彝族自治州武定县农贸市场 See Zanthoxylum bungeanum ./See Zanthoxylum bungeanum.
TCMBANKHE008517 Folium Artemisiae Argyi 艾叶 1. To warm the channels and stop bleeding. 2. To dispel cold and stop pain/Cold pain in abdomen, menstrual disorder due to cold, infertility due to uterus cold, blood ejection, spontaneous external bleeding, flooding and spotting, fetal spotting, itchy skin.
TCMBANKHE007847 Caulis Millettiae; Caulis spatholobi 鸡血藤 To enrich the blood, to activate blood circulation, and to remove obstruction of the channels and collaterals./Treatment of menstrual disorders, anemia, numbness and paralysis, rheumatic arthralgia.
TCMBANKHE003964/YEM-214/XU-446 Zanthoxylum nitidum|Zanthoxylum nitidum (Roxb.)DC 入地金牛|两面针 两面针 云南民族药物志:第二卷|广东省廉江市石岭镇 To dispel wind and free network vessels, disperse swelling and relieve pain./Wind-damp bone pain, stomachache, toothache, throat impediment, scrofula, burns and scalds. 傣族/哈尼族
TCMBANKHE006280/YEM-249 Dendrobium densiflorum|Dendrobium densiflorum Lindl. 密花石斛 密花石斛 云南民族药物志:第二卷 See Dendrobium nobile./See Dendrobium nobile. 基诺族/瑶族
TCMBANKHE003737/YEM-277 Nicotiana tabacum|Nicotiana tabacum L. 烟草 烟草 云南民族药物志:第二卷 To move qi and relieve pain, resolve toxin and kill worms./Food stagnation, qi bind pain, welling abscess and flat abscess, clove sore, scab and lichen, snake bite, dog bite. 阿昌族/傣族/德昂族/哈尼族/基诺族/景颇族/傈僳族/佤族/彝族
TCMBANKHE003727/YEM-310 Brassica oleracea var. capitata|Brassica oleracea L. var. capitata L. 甘蓝|莲花白 莲花白 云南民族药物志:第二卷 To clear heat and disinhibit damp, dissipate binds and relieve pain, boost kidney and supplement vacuity./Damp-heat jaundice, pain from ulcer in digestive tract, stiffness in joints, vacuity detriment. 傣族
TCMBANKHE008188/YEM-310 Brassica oleracea var. capitata|Brassica oleracea L. var. capitata L. 甘蓝|莲花白 莲花白 云南民族药物志:第二卷 To clear heat and disinhibit damp, dissipate binds and relieve pain, boost kidney and supplement vacuity./Damp-heat jaundice, pain from ulcer in digestive tract, stiffness in joints, vacuity detriment. 傣族
TCMBANKHE006329/YEM-428/XU-284/XU-636 Zanthoxylum acanthopodium|Zanthoxylum acanthopodium DC. 刺花椒 刺花椒 云南民族药物志:第三卷|云南省曲靖市会泽县 To warm center and dissipate cold, kill worms and relieve pain./Cold pain in stomach duct and abdomen, wind-cold-damp impediment, knocks and falls, abdominal pain due to worm accumulation. 哈尼族/佤族/瑶族
TCMBANKHE005589/YEM-543 Aegle marmelos|Aegle marmelos (L.)Corr. 木橘|三叶木桔 印度枳 云南民族药物志:第三卷 To check dysentery and diarrhea, disinhibit throat and disperse swelling./Chronic diarrhea, abdominal pain, dysentery, swelling pain in throat. 傣族/藏族
TCMBANKHE004550/YEM-551 Artemisia capillaris|Artemisia capillaris Thunb. 茵陈蒿 茵陈 云南民族药物志:第三卷 To clear heat and disinhibit damp, abate jaundice./Hepatitis, jaundice, infective cholecystitis, hyperlipemia, inhibited urination, damp sore, itchy skin. 阿昌族/傣族/德昂族/景颇族/傈僳族/瑶族/彝族/藏族/壮族
TCMBANKHE008264/YEM-551 Artemisia scoparia [Syn. Artemisia capillaris var. scoparia]|Artemisia capillaris Thunb. 黄蒿|茵陈蒿 茵陈 云南民族药物志:第三卷 See Artemisia capillaris./See Artemisia capillaris. 阿昌族/傣族/德昂族/景颇族/傈僳族/瑶族/彝族/藏族/壮族
TCMBANKHE008476/YEM-68 Artemisia annua|Artemisia annua L. 黄花蒿 黄花蒿 云南民族药物志:第一卷 To clear heat, resolve summerheat, eliminate steam, interrupt malaria./Summerheat-heat, summerheat-damp, damp warmth, yin vacuity fever, malaria, jaundice. 阿昌族/白族/傣族/德昂族/独龙族/景颇族/傈僳族/纳西族/怒族/瑶族/彝族/藏族/壮族
TCMBANKHE006570/YEM-68 Herba Artemisiae Annuae|Artemisia annua L. 青蒿|黄花蒿 黄花蒿 云南民族药物志:第一卷 To remove summer-heat, to relieve consumptive fever,and to stop malarial attacks./See Artemisia annua. 阿昌族/白族/傣族/德昂族/独龙族/景颇族/傈僳族/纳西族/怒族/瑶族/彝族/藏族/壮族
TCMBANKHE005522/YEM-745/XU-411 Fructus Gardeniae|Gardenia jasminoides(L.)Ellis|Gardenia jasminoides 栀子 栀子 云南民族药物志:第四卷|广东省廉江市石岭镇 1. To clear heat and reduce fire; 2. To cool blood and release toxins; 3. To eliminate dampness/Acute icterohepatitis, febrile diseases, vexation, melancholia, restlessness, stagnation of damp-heat in liver and gall, fever, jaundice, short voidings of reddish urine, blood ejection, spontaneous external bleeding, dysentery with hematochezia and hematuria. 阿昌族/布依族/傣族/德昂族/景颇族/傈僳族/苗族/水族/瑶族/彝族/壮族
TCMBANKHE005331/YNS-287/YEM-823/XU-183 Scoparia dulcis|Scoparia dulcis L. 野甘草 野甘草|冰糖草 云南药材标准:第三册|云南民族药物志:第四卷|广西省钦州市钦北区 用于治疗偏头痛,腰痛,尿频尿痛,肾炎,疮疖,外用治痱子,皮肤湿疹,主治小儿高热,咽喉肿痛,咳嗽,牙痛,肠炎。|To clear heat and resolve toxin, disinhibit urine and disperse edema./Lung heat cough, summerheat-heat diarrhea, beriberi with general edema, child measles, papules, eczema, prickly heat, laryngitis, erysipelas. 阿昌族/傣族/德昂族/基诺族/景颇族/傈僳族/佤族
TCMBANKHE004187/YEM-87 Herba Dendrobii|Dendrobium nobile Lindl. 石斛 金钗石斛 云南民族药物志:第一卷 Treatment of thirst due to impairment to yin or deficiency of body fluid, loss of appetite with nausea, fever in deficiency conditions after a severe disease, impaired vision./1. Dendrobine, one of its components, exerts the effects of raising the level of blood sugar, hypotensive, antipyretic and analgesic.2. Its infusion is cardio-inhibitory.3. Low dosage causes excitation while high dosage causes inhibition of the intestine of rabbits in vitro. 阿昌族/傣族/德昂族/基诺族/景颇族/傈僳族/彝族/藏族
TCMBANKHE007056/YEM-9 Herba Lobeliae Chinensis|Lobelia chinensis Lour. 半边莲 半边莲 云南民族药物志:第一卷 To cause diuresis, and to remove toxic heat./Edema, edema and enlarged abdomen, edema in face and foot, swollen welling abscess and clove sores, snake or insect bites. 阿昌族/傣族/德昂族/景颇族/傈僳族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000139 POR CPR; CYPOR; P450R cytochrome p450 oxidoreductase
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000204 CXCL8 GCP-1; GCP1; IL8; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1; SCYB8 C-X-C motif chemokine ligand 8
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000221 GRIA2 GLUR2; GLURB; GluA2; GluR-K2; HBGR2; gluR-2; gluR-B glutamate ionotropic receptor AMPA type subunit 2
TCMBANKGE000274 CCL2 GDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; SCYA2; SMC-CF C-C motif chemokine ligand 2
TCMBANKGE000276 NOS1 IHPS1; N-NOS; NC-NOS; NOS; bNOS; nNOS nitric oxide synthase 1
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000633 ADRB2 ADRB2R; ADRBR; B2AR; BAR; BETA2AR adrenoceptor beta 2
TCMBANKGE000646 DECR1 DECR; NADPH; SDR18C1 2,4-dienoyl-CoA reductase 1
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001098 NFKBIA EDAID2; IKBA; MAD-3; NFKBI NFKB inhibitor alpha
TCMBANKGE001107 NOS3 ECNOS; eNOS nitric oxide synthase 3
TCMBANKGE001184 RELA CMCU; NFKB3; p65 RELA proto-oncogene, NF-kB subunit
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001467 LTA4H - leukotriene A4 hydrolase
TCMBANKGE001755 MAOB - monoamine oxidase B
TCMBANKGE003625 SLC6A4 5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT solute carrier family 6 member 4
TCMBANKGE005535 CHRM1 HM1; M1; M1R cholinergic receptor muscarinic 1
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE006373 TYW1 RSAFD1; TYW1A; YPL207W tRNA-yW synthesizing protein 1 homolog
TCMBANKGE007924 PKIA PRKACN1 cAMP-dependent protein kinase inhibitor alpha
TCMBANKGE008919 DCT TRP-2; TYRP2 dopachrome tautomerase
TCMBANKGE009863 MTRR MSR; cblE 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
TCMBANKGE011356 NDOR1 CIAE1; NR1; bA350O14.9 NADPH dependent diflavin oxidoreductase 1
TCMBANKGE013930 TYR ATN; CMM8; OCA1; OCA1A; OCAIA; SHEP3 tyrosinase
TCMBANKGE014050 GABRA1 ECA4; EIEE19; EJM; EJM5 gamma-aminobutyric acid type A receptor subunit alpha1
TCMBANKGE014901 TYRP1 CAS2; CATB; GP75; OCA3; TRP; TRP1; TYRP; b-PROTEIN tyrosinase related protein 1
TCMBANKGE014941 DPEP1 MBD1; MDP; RDP dipeptidase 1