Compound Summary


  Compound Information

药名:

scopolin

别名:

scopolin ; Scopolin; 6-METHOXY-7-{[(2S,3R,4S,5S,6R)-3,4,5-TRIHYDROXY-6-(HYDROXYMETHYL)OXAN-2-YL]OXY}-3,4-DIHYDRO-1-BENZOPYRAN-2-ONE;6-methoxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one; 7-(beta-D-glucopyranosoyloxy)-6-methoxy-2H-1-benzopyran-2-one; 6-methoxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-chromen-2-one; CHEBI:16065; 6-methoxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-coumarin; ZINC04082214; STOCK1N-54345; 6-methoxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-chromen-2-one; 6-methoxy-7-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-tetrahydropyranyl]oxy]-2-chromenone;6-methoxy-2-oxo-2H-chromen-7-yl beta-D-glucopyranoside

分子式:

C16H18O9

Smiles:

COC1=C(C=C2C(=C1)C=CC(=O)O2)OC3C(C(C(C(O3)CO)O)O)O

成分:

HBIN043446;HBIN012506

OB_score:

25.502338

CAS_id:

531-44-2

SymMap_id:

SMIT01614;SMIT02863;SMIT13772

TCMID_id:

19530

TCMSP_id:

MOL000216;MOL002218;MOL009299;MOL013074

PubChem_id:

439514


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000232 川射干
TCMBANKHE000724 Diospyros maritima 海狮
TCMBANKHE001046 胡芦巴 Hyperlipemia, kidney vacuity cold, cold pain in lesser-abdomen, mounting qi , beriberi.
TCMBANKHE001687 大皂荚
TCMBANKHE001875 Herba Clinopodii 断血流 To arrest bleeding./Treatment of excessive menstrual discharge, hemorrhage from hysteromyoma, hematuria, epistaxis, gingival bleeding, traumatic bleeding.
TCMBANKHE003148 天山雪莲
TCMBANKHE003402 十大功劳根
TCMBANKHE003616 Rhus lanceolata
TCMBANKHE006944 Caulis Erycibes 丁公藤 To dispel wind and deprive dampness, reduce swelling, relieve pain./Wind-damp impediment pain, hemiplegia, painful swelling from knocks and falls.
TCMBANKHE005521 Ilex pubescens var. glaber 秃毛冬青 See Ilex pubescens ./See Ilex pubescens.
TCMBANKHE005598 Erycibe schmidtii 光叶丁公藤 See Erycibe obtusifolia./See Erycibe obtusifolia.
TCMBANKHE003952 Folium Rhododendri Daurici 满山红 Acute bronchitis, chronic bronchitis.
TCMBANKHE004244 Radix Paeoniae Alba 白芍 1. To nourish blood and consolidate the yin; 2. To pacify the liver and stop pain; 3. To soothe liver yang/Headache and dizziness, pain in rib-side, abdominal pain, spasm in limbs, anemia with yellow complexion, menstrual disorder, profuse menstruation, spontaneous sweating, night sweating.
TCMBANKHE004258 Radix Angelicae sinensis 当归根 To enrich blood, activate blood circulation, regulate menstruation, relieve pain, and relax bowels./Women’s diseases, blood deficiency syndrome, menstrual disorder, amenorrhea and dysmenorrhea, dysmenorrhea due to anemia, thrombophlebitis, neuralgia, arthritis, chronic nephritis, constrictive aortitis, blood vaculty, pernicious anemia, anemia due to folic acid deficiency, dysentery, hepatitis, Raynaud’s disease, lumbago, various pains due to blood stasis and rheumatic impediment, sores, welling abscess, constipation, ulcer in gastrointestinal tract, skin diseases, eczema, dermatitis, neurodermatitis, psoriasis.
TCMBANKHE006088 Patrinia scabiosaefolia 黄花败酱 See Patrinia villosa ./See Patrinia villosa.
TCMBANKHE004459 Fructus Lycii 枸杞子 To benefit the liver and the kidney, to replenish vital essence and to improve eyesight./Lassitude in lumbus and knees, emission, dizziness and dim vision, lung disease with cough, diabetes mellitus.
TCMBANKHE004523 Flos Gossampini 木棉花 Diarrhea, dysentery, hemoptysis, blood ejection, flooding, incised wound and bleeding, sore toxin, eczema.
TCMBANKHE004649 Convolvulus scammonia 司格蒙旋花
TCMBANKHE008626 Cortex Lycii Radicis 地骨皮 To reduce heat in blood, to relieve consumptive fever, and to remove heat from the lung./1. Its decoction, infusion, tincture and injection exert a hypotensive effect on anesthetized or unanesthetized animals.2. Antipyretic. Reducing vaccine-induced fever in rabbits.3. Its extract lowers serum cholesterol level in rabbits,4. Its decoction reduces blood sugar level in rabbits5. An active component, betaine, possesses a lipocaic effect.
TCMBANKHE006650 Lycium barbarum 宁夏枸杞子 See Lycium chinense./See Lycium chinense.
TCMBANKHE004788 Saussurea involucrata; Saussurea tridactyla var. maidugonla 雪莲 To warm kidney and invigorate yang , dispel wind and overcome damp, quicken blood and free menstruation./Impotence, weakness in lumbus and knees, wind-damp impediment pain, menstrual disorder, amenorrhea, uterus cold and abdominal pain, cold rheum cough.
TCMBANKHE005064 Pimpinella thelungiana 羊红膻 To boost qi and fortify spleen, nourish heart and quiet spirit, relieve cough and dispel phlegm./Kersan disease, palpitation and shortness of breath, cough.
TCMBANKHE005139 Radix Angelicae Dahuricae 白芷 To dispel wind, to remove damp, to clear the stuffed nose, to relieve pain, and to promote the subsidence ofswelling and drainage of pus./Wind-cold common cold, nasal congestion, headache (especially in forehead and superciliary region), toothache, infections, acute mastitis, sores, excessive leukorrhea, stomachache.
TCMBANKHE005210 Flos Inulae 旋覆花 To relieve cough, eliminate phlegm, promote diuresis, and arrest vomiting./1. Its alcoholic extract is a diuretic in experimental rabbits.2. The decoction inhibits the growth Staphylococcus aureus and pneumococcus in vitro.
TCMBANKHE005371 Scopolia japonica 东莨菪碱 To resolve tetany and settle pain, constrain sweat and astringe intestines./Various pains, mental manic agitation, swelling toxin of sore and welling abscess, anthrax, bleeding due to external injury, body lichen.
TCMBANKHE005742 Atropa belladonna 颠茄 To resolve spasm and relieve pain, inhibit secretion./Gastric ulcer, duodenal ulcer, colic of gastrointestinal tract, cholecystalgia, renal colic, vomiting nausea, night sweating, drooling.
TCMBANKHE008642 Murraya paniculata [Syn. Chalcas paniculata] 九里香 To move qi and quicken blood, dissipate stasis and relieve pain, resolve toxin and disperse swelling, anesthetize and settle pain./Pain in stomach duct, wind-damp impediment pain, painful swelling from knocks and falls, sore and welling abscess, snake or insect bites, local anesthesia.
TCMBANKHE007314 Rhododendron micranthum 照山白 To relieve cough and transform phlegm, dispel wind and free network vessels, regulate menstruation and relieve pain./Cough and asthma with abundant phlegm, wind-damp impediment pain, lumbago, menstrual disorder, dysmenorrhea, fracture.
TCMBANKHE006184 Radix Angelicae Pubescentis 独活 To relieve rheumatic conditions, and to remove obstruction from the channels and relieve pain./Wind-cold-damp impediment (especially in lower part of body), pain in lumbus and knees, headache, toothache.
TCMBANKHE006313 Radix et Rhizoma Rhei 大黄 To cause catharsis and purge away heat, to reduce heat in blood and counteract toxicity, and to eliminate blood stasis and stimulate menstrual discharge./Repletion heat constipation, accumulation with abdominal pain, damp-heat jaundice, acute icterohepatitis, red eyes, swollen throat, intestinal welling abscess and abdominal pain, bleeding of digestive tract, chronic diarrhea, indigestion, acute appendicitis, acute peritonitis, ileus, cholecystitis, gallstones, swollen welling abscess and clove sores, amenorrhea due to blood stasis, knocks and falls, burns and scalds.
TCMBANKHE008662 Radix Paeoniae Alba 白芍 1. To nourish blood and consolidate the yin; 2. To pacify the liver and stop pain; 3. To soothe liver yang/Headache and dizziness, pain in rib-side, abdominal pain, spasm in limbs, anemia with yellow complexion, menstrual disorder, profuse menstruation, spontaneous sweating, night sweating.
TCMBANKHE007382 Coronilla varia 多变小冠花
TCMBANKHE007386 Pterospermum lanceaefolium 窄叶半枫荷 To quicken blood and stanch bleeding./Bleeding due to external injury.
TCMBANKHE006697 Aralia fargesii 龙眼独活 See Aralia cordata ./See Aralia cordata.
TCMBANKHE006960 Fraxinus szaboana [Syn. Fraxinus chinensis var. acuminata] 尖叶梣 See Fraxinus rhynchophylla ./See Fraxinus rhynchophylla .
TCMBANKHE009006 Caltha palustris 马蹄叶 To expel wind, resolve summerheat, quicken blood and disperse swelling./Wind damage common cold, summerheat stroke with sand, knocks and falls, burns and scalds.
TCMBANKHE007776 Prunus serotina 野黑樱桃;野黑樱
TCMBANKHE007779 Saussurea superba [Syn. Saussurea hieracioides ] 长毛风毛菊 To drain water retension./Edema, ascites (hydroperitoneum), effusion in thorax.
TCMBANKHE008006 Urtica dioica 异株荨麻 See Urtica cannabina./See Urtica cannabina.
TCMBANKHE009004 Saussurea involucrata 雪莲 To warm kidney and invigorate yang , dispel wind and overcome damp, quicken blood and free menstruation./Impotence, weakness in lumbus and knees, wind-damp impediment pain, menstrual disorder, amenorrhea, uterus cold and abdominal pain, cold rheum cough.
TCMBANKHE007978 Uncaria sinensis 华钩藤 See Uncaria rhynchophylla./See Uncaria rhynchophylla.
TCMBANKHE007150/YEM-237/XU-798 Helianthus annuus|Helianthus annuus L. 向日葵籽|向日葵 向日葵 云南民族药物志:第二卷|云南省昆明市呈贡区 To outthrust papules, check dysentery, outthrust welling abscess and pus./Blood dysentery, welling abscess with pus swelling. 阿昌族/傣族/德昂族/景颇族/傈僳族/藏族
TCMBANKHE005971/YEM-237/XU-798 Helianthus annuus|Helianthus annuus L. 向日葵茎髓|向日葵 向日葵 云南民族药物志:第二卷|云南省昆明市呈贡区 To clear heat, disinhibit urine, relieve cough./Blood strangury, urethral stone, chyluria, inhibited urination. 阿昌族/傣族/德昂族/景颇族/傈僳族/藏族
TCMBANKHE008331/YEM-237/XU-798 Helianthus annuus|Helianthus annuus L. 向日葵叶|向日葵 向日葵 云南民族药物志:第二卷|云南省昆明市呈贡区 To lower blood pressure, interrupt malaria, resolve toxin./Hypertension, malaria, clove sore. 阿昌族/傣族/德昂族/景颇族/傈僳族/藏族
TCMBANKHE003737/YEM-277 Nicotiana tabacum|Nicotiana tabacum L. 烟草 烟草 云南民族药物志:第二卷 To move qi and relieve pain, resolve toxin and kill worms./Food stagnation, qi bind pain, welling abscess and flat abscess, clove sore, scab and lichen, snake bite, dog bite. 阿昌族/傣族/德昂族/哈尼族/基诺族/景颇族/傈僳族/佤族/彝族
TCMBANKHE004550/YEM-551 Artemisia capillaris|Artemisia capillaris Thunb. 茵陈蒿 茵陈 云南民族药物志:第三卷 To clear heat and disinhibit damp, abate jaundice./Hepatitis, jaundice, infective cholecystitis, hyperlipemia, inhibited urination, damp sore, itchy skin. 阿昌族/傣族/德昂族/景颇族/傈僳族/瑶族/彝族/藏族/壮族
TCMBANKHE008264/YEM-551 Artemisia scoparia [Syn. Artemisia capillaris var. scoparia]|Artemisia capillaris Thunb. 黄蒿|茵陈蒿 茵陈 云南民族药物志:第三卷 See Artemisia capillaris./See Artemisia capillaris. 阿昌族/傣族/德昂族/景颇族/傈僳族/瑶族/彝族/藏族/壮族
TCMBANKHE004417/YEM-588 Micromelum integerrimum|Micromelum integerrimum(Buch.-Ham.)Wight et Arn.ex M.Roem. 小芸木 癞蛤蟆跌打 云南民族药物志:第三卷 To course wind and resolve exterior, warm center and move qi, dissipate stasis and disperse swelling./Influenza, common cold with cough, stomachache, wind-damp impediment pain, painful swelling from knocks and falls, fracture. 佤族/壮族
TCMBANKHE004643/YEM-590/XU-716 Folium Mori|Morus alba L.|Morus alba 桑叶|桑 桑叶 云南民族药物志:第三卷|云南省昭通市盐津县 To dispel wind-heat and to remove heat from the lung, to subdue hyperactivity of the liver and improve eyesight./Wind-heat common cold, lung heat dry cough, dizziness and headache, red eyes and clouded vision. 阿昌族/布依族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/水族/佤族/彝族/藏族
TCMBANKHE008476/YEM-68 Artemisia annua|Artemisia annua L. 黄花蒿 黄花蒿 云南民族药物志:第一卷 To clear heat, resolve summerheat, eliminate steam, interrupt malaria./Summerheat-heat, summerheat-damp, damp warmth, yin vacuity fever, malaria, jaundice. 阿昌族/白族/傣族/德昂族/独龙族/景颇族/傈僳族/纳西族/怒族/瑶族/彝族/藏族/壮族
TCMBANKHE007363/YEM-744/XU-850 Radix et Rhizoma Rhei|Rheum palmatum L.|Rheum palmatum 大黄; 生锦纹; 生军|掌叶大黄 掌叶大黄 云南民族药物志:第四卷|西藏昌都地区芒康县 To cause catharsis and purge away heat, to reduce heat in blood and counteract toxicity, and to eliminate blood stasis and stimulate menstrual discharge.; Treatment of fever with constipation, retention of the feces and abdominal pain, dysentery with inadequate discharge from the bowels, jaundice caused by damp-heat, haematemesis, epistaxis, inflammation of eye and swelling of the throat due to heat in the blood, appendicitis with abdominal pain, boils, sores and abscess, amenorrhea due to blood stasis, traumatic injuries, hemorrhage from the upper gastrointestinal tract. External use for scalds and burns.Radixet Rhizoma Rhei (stir-fried with wine) Inflammation of the eye, swelling of the throat and painful swelling of the gums. Radix et Rhizoma Rhei (prepared) Boils, sores and abscess. Radix et Rhizoma Rhei (carbonized) Hemorrhage with blood stasis due to heat in the blood./Repletion heat constipation, accumulation with abdominal pain, damp-heat jaundice, acute icterohepatitis, red eyes, swollen throat, intestinal welling abscess and abdominal pain, bleeding of digestive tract, chronic diarrhea, indigestion, acute appendicitis, acute peritonitis, ileus, cholecystitis, gallstones, swollen welling abscess and clove sores, amenorrhea due to blood stasis, knocks and falls, burns and scalds.; 1. Sennoside A is the component for purgation.2. Promoting biliary secretion and enhancing the amount of bilirubin and bile acid.3. Rhein and Emodin exert bacteriostatic effect by inhibting the synthesis of DNA, RNA and protein in bacteria4. Emodin is a component for hypotensive5. Oral use of its extract reduces the raio of serum cholesterol and total phospholipid in rabbits with hypercholesterolemia.6. Chrysophanol, an other active component, exerts a hemostatic effect. 阿昌族/傣族/德昂族/回族/景颇族/傈僳族/彝族/藏族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1
TCMBANKGE014941 DPEP1 MBD1; MDP; RDP dipeptidase 1