Compound Summary


  Compound Information

药名:

Corydaldine

别名:

Maybridge4_000744; 6,7-Dimethoxy-3,4-dihydro-1(2H)-isoquinolinone; 6,7-dimethoxy-3,4-dihydro-2H-isoquinolin-1-one; Oprea1_116786; IDI1_031326; ZINC04324103; 6,7-dimethoxy-3,4-dihydroisocarbostyril

分子式:

C11H13NO3

Smiles:

COC1=C(C=C2C(=C1)CCNC2=O)OC

成分:

HBIN021540

OB_score:

49.303755

CAS_id:

493-49-2

SymMap_id:

SMIT05060

TCMSP_id:

MOL002896

PubChem_id:

610097


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE003748 Rhizoma Coptidis 黄连 To remove damp-heat, quench fire and counteract toxicity./Febrile infectious diseases, dysentery, blood ejection, spontaneous external bleeding, diphtheria, infection of upper respiratory tract, scarlatina, typhoid fever, acute conjunctivitis, otitis media, acute surgical infection, septicemia, hepatitis, trichomoniasis, eruptive dermatitis, hypertension, vexation and agitation, clouded spirit with delirious speech, damp-heat glomus in chest, damp-heat diarrhea dysentery, insomnia and vexation due to effulgent fire, stomach heat vomiting, swift digestion with rapid hungering, red eyes with pain due to liver fire, heat toxin sores, clove sore running yellow, gum swelling and pain, mouth sore, tongue sores, genital swelling, bleeding from hemorrhoids, eczema, scalds.

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000309 SCN5A CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 sodium voltage-gated channel alpha subunit 5
TCMBANKGE000633 ADRB2 ADRB2R; ADRBR; B2AR; BAR; BETA2AR adrenoceptor beta 2
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001194 ADRA2A ADRA2; ADRA2R; ADRAR; ALPHA2AAR; ZNF32 adrenoceptor alpha 2A
TCMBANKGE001467 LTA4H - leukotriene A4 hydrolase
TCMBANKGE001506 ADRA1B ADRA1; ALPHA1BAR adrenoceptor alpha 1B
TCMBANKGE001755 MAOB - monoamine oxidase B
TCMBANKGE001943 ADRA1D ADRA1; ADRA1A; ADRA1R; ALPHA1; DAR; dJ779E11.2 adrenoceptor alpha 1D
TCMBANKGE003625 SLC6A4 5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT solute carrier family 6 member 4
TCMBANKGE005535 CHRM1 HM1; M1; M1R cholinergic receptor muscarinic 1
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE006943 CHRM3 EGBRS; HM3; PBS cholinergic receptor muscarinic 3
TCMBANKGE007924 PKIA PRKACN1 cAMP-dependent protein kinase inhibitor alpha
TCMBANKGE009256 SLC6A2 NAT1; NET; NET1; SLC6A5 solute carrier family 6 member 2
TCMBANKGE009758 PDE3A CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB phosphodiesterase 3A
TCMBANKGE012155 SLC6A3 DAT; DAT1; PKDYS; PKDYS1 solute carrier family 6 member 3
TCMBANKGE014050 GABRA1 ECA4; EIEE19; EJM; EJM5 gamma-aminobutyric acid type A receptor subunit alpha1
TCMBANKGE014423 ADRA1A ADRA1C; ADRA1L1; ALPHA1AAR adrenoceptor alpha 1A
TCMBANKGE014790 ADRB1 ADRB1R; B1AR; BETA1AR; FNSS2; RHR adrenoceptor beta 1
TCMBANKGE014941 DPEP1 MBD1; MDP; RDP dipeptidase 1