Compound Summary


  Compound Information

药名:

cuscutin

别名:

bergenin;3,4,4a,10b-Tetrahydro-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxypyrano(3,2-c)(2)benzopyran-6(H)-one; D01040; Bergenin [JAN]; 477-90-7 (ANYDROUS); Bergenin; Bergenin (JAN); Pyrano[3,2-c][2]benzopyran-6(2H)-one, 3,4,4a,10b-tetrahydro-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-, (2R,3S,4S,4aR,10bS)-; CHEMBL1512567; AIDS-031337; HMS2268E16; 3,4,8,10-Tetrahydroxy-2-(hydroxymethyl)-9-methoxy-3,4,4a,10b-tetrahydropyrano[3,2-c]isochromen-6(2H)-one; (2R,3S,4S,4aR,10bS)-3,4,8,10-tetrahydroxy-9-methoxy-2-methylol-3,4,4a,10b-tetrahydro-2H-pyrano[3,2-c]isochromen-6-one; MLS000563027; 4-Methoxy-2-(tetrahydro-3,4,5-trihydroxy-6-(hydroxymethyl)pyran-2-yl)alpha-resorcylic acid gamma lactone; bergenin ; BB_NC-1749; ZINC04046820; SMR001215803; C09919; 477-90-7; (2R,3S,4S,4aR,10bS)-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-3,4,4a,10b-tetrahydro-2H-pyrano[3,2-c]isochromen-6-one; AIDS031337

分子式:

C14H16O9

Smiles:

COC1=C(C=C2C(=C1O)C3C(C(C(C(O3)CO)O)O)OC2=O)O

成分:

HBIN022028;HBIN017919

CAS_id:

477-90-7

SymMap_id:

SMIT18666;SMIT01295;SMIT04996

TCMID_id:

2312

TCMSP_id:

MOL002816

PubChem_id:

66065


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE003548 Caesalpinia digyna 二次陨石
TCMBANKHE005198 Herba Saxifragae 虎耳草 For clearing heat and removing toxic substances/Wind papules, eczema, otitis media, erysipelas, cough with blood ejection, pulmonary welling abscess, flooding and spotting, hemorrhoids.
TCMBANKHE004154 Ardisiae japonicae 矮地茶 1. To eliminate phlegm and relieving cough.2. To promote diuresis to deprive dampness. 3. To activate blood circulation and stop bleeding./1. Bergenin, an active comonent, is an expectorant. 2. Its volatile oil or flavone can relieve bronchospasm induced by histamine in vitro. 3. Its decoction inhibits the growth of Pneumococcus, Staphylococcus aureus and influenza virus in vitro.
TCMBANKHE006301 Mallotus philippinensis 吕宋楸毛 To kill worms and relieve diarrhea./Taeniasis, ascariasis, oxyuria disease.
TCMBANKHE004610 Ramulus Uncariae cum Uncis 钩藤 To remove heat, subdue hyperactivity of the liver, and arrest convulsions./Infant fright wind and night crying, exuberant heat stirring wind, epilepsy of pregnancy, liver yang dizziness, liver fire headache.
TCMBANKHE006466 Bergenia crassifolia 厚叶岩白菜 To supplement vacuity and stanch bleeding, relieve cough and settle asthma./Dizziness, cough, asthma, blood ejection, hemoptysis.
TCMBANKHE004907 连钱草 Treatment of acute urinary infection, urolithiasis, acute jaundice, painful swelling in sores and carbuncies, traumatic injuries.
TCMBANKHE005391 Ardisia colorata 有色紫金牛
TCMBANKHE007611 大叶落新妇
TCMBANKHE007833 Astilbe macroflora 大花落新妇
TCMBANKHE006149 Rodgersia aesculifolia 木荷 To clear heat and transform damp, engender flesh and stanch bleeding./Damp-heat dysentery, chronic diarrhea, white turbidity, vaginal discharge, flooding and spotting, blood ejection, spontaneous external bleeding, hematochezia, sore toxin, incised wound.
TCMBANKHE006238 Astilbe chinensis 落新妇 To dispel wind, clear heat, suppress cough./Wind-heat common cold, headache and generalized pain, cough.
TCMBANKHE006442 Symplocos chinensis 华山矾 To clear heat and resolve toxin, transform phlegm and interrupt malaria, free network vessels and relieve pain./Common cold with fever, diarrhea and dysentery, swelling of sores and boils, poisonous snake bites, malaria, pain in sinews and bones, knocks and falls.
TCMBANKHE007443 Folium Ginseng 人参叶 To nourish qi and lung, expel summer-heat, to promote fluid secretion./Summerheat-heat and thirst, febrile diseases fluid damage, stomach yin insufficiency, diabetes mellitus, dry cough due to lung dryness, vacuity-fire toothache.
TCMBANKHE006991 胡黄连 Steaming bone tidal fever due to yin vacuity, night sweating, child gan accumulation, indigestion, abdominal distention and emaciation, dysentery, fever, gastrointestinal damp-heat diarrhea, hemorrhoids.
TCMBANKHE008512 radix Peucedani 前胡 To dispel wind and remove heat, and to relieve cough and resolve phlegm ./Cough, externally contracted wind-heat, lung heat phlegm depression, cough and asthma with abundant phlegm, sticky phlegm, retching counterflow and reduced food intake, fullness and oppression in chest and diaphragm.
TCMBANKHE009095/YNS-1 Dysosma versipellis [Syn. Podophyllum versipelle ]|Dysosma versipellis (Hance) M. cheng ex Ying 鬼臼|八角莲 八角莲 云南药材标准:第一册 清热解毒,化痰散结,祛瘀消肿。用于咳嗽,咽喉肿痛,痈肿痔疮,瘰疬,跌打损伤,毒蛇咬伤。|See Dysosma pleiantha./See Dysosma pleiantha .
TCMBANKHE006105/XU-484/XU-555/XU-767 Mallotus japonicus|Mallotus japonicus var. oreophilus 野梧桐; 梧桐叶|绒毛野桐 四川省凉山州会理县 To clear heat and resolve toxin, promote contraction and stanch bleeding./Gastric ulcer, duodenal ulcer, hepatitis, hematuria, vaginal discharge, sores, bleeding due to external injury.
TCMBANKHE005630/YEM-176 Bergenia purpurascens|Bergenia purpurascens (Hook.f.et Thoms.) Engl. 岩白菜 岩白菜 云南民族药物志:第一卷 To enrich and supplement, check vomiting and stanch bleeding./Vacuity with dizziness, taxation damage cough, blood ejection, hemoptysis, strangury-turbidity, vaginal discharge, toxin swelling. 白族/拉祜族/傈僳族/苗族/纳西族/普米族/佤族/瑶族/藏族/壮族
TCMBANKHE004783/YEM-493 Ardisia crispa|Ardisia crispa (Thunb.) A. DC. 百两金 百两金 云南民族药物志:第三卷 To clear heat and disinhibit throat, dispel phlegm and disinhibit damp, quicken blood and resolve toxin./Swelling pain in throat, cough with inhibited phlegm, damp-heat jaundice, dribbling pain of urination, wind-damp impediment pain, knocks and falls, clove sore, innominate toxin swelling, snake bite. 苗族/瑶族/彝族
TCMBANKHE005939/YEM-748 Ardisia japonica|Ardisia japonica(Hornst.)Blume 紫金牛 紫金牛 云南民族药物志:第四卷 To suppress cough, dispel phlegm, quicken blood, disinhibit urine, resolve toxin./Chronic trachitis, hepatitis, acute nephritis, chronic nephritis, tuberculosis and hemoptysis, blood ejection, dysentery, hypertension, mounting qi, taxation damage and strength desertion, aching sinews and bones, toxin swelling. 阿昌族/傣族/德昂族/景颇族/傈僳族/苗族/瑶族/壮族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE014941 DPEP1 MBD1; MDP; RDP dipeptidase 1