Compound Summary


  Compound Information

药名:

(+)-cyclo-olivil

别名:

(+)-Cycloolivil;cycloolivil;(2S,3S,4S)-4-(4-hydroxy-3-methoxyphenyl)-2,3-bis(hydroxymethyl)-7-methoxytetralin-2,6-diol; (2S,3S,4S)-4-(4-hydroxy-3-methoxyphenyl)-2,3-bis(hydroxymethyl)-7-methoxy-3,4-dihydro-1H-naphthalene-2,6-diol; ACon1_001444; MEGxp0_001281; (+)-cycloolivil; (2S,3S,4S)-4-(4-hydroxy-3-methoxy-phenyl)-7-methoxy-2,3-dimethylol-tetralin-2,6-diol; (2S,3S,4S)-4-(4-hydroxy-3-methoxy-phenyl)-2,3-bis(hydroxymethyl)-7-methoxy-tetralin-2,6-diol; (2S,3S,4S)-4-(4-hydroxy-3-methoxy-phenyl)-2,3-bis(hydroxymethyl)-7-methoxy-3,4-dihydro-1H-naphthalene-2,6-diol

分子式:

C20H24O7

Smiles:

COC1=C(C=C2C(C(C(CC2=C1)(CO)O)CO)C3=CC(=C(C=C3)O)OC)O

成分:

HBIN022324;HBIN022323;HBIN022322

OB_score:

24.504734

SymMap_id:

SMIT19018;SMIT03273;SMIT14865

TCMID_id:

26061;4520;33242

TCMSP_id:

MOL000740

PubChem_id:

5316262


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE002474 Saussurea laniceps 绵头雪莲花 To warm kidney and invigorate yang , regulate menstruation and stanch bleeding./Impotence, limp aching lumbus and knees, vaginal discharge, menstrual disorder, wind-damp impediment, bleeding due to external injury.
TCMBANKHE005158 淫羊藿 Angina pectoris, chronic bronchitis, neurasthenia, climacteric hypertension, poliomyelitis, impotence and emission, limp wilting sinew and bone, wind-damp impediment pain, hypertonicity and numbness.
TCMBANKHE007889 杜仲叶 Lumbar and back pain, limp aching inability of legs and knees, hypertension.
TCMBANKHE007417 Flos Rosae chinensis 月季花 1. To invigorate blood and regulate menstruation; 2. To reduce swelling/Menstrual disorder, dysmenorrhea, knocks and falls, blood stasis swelling and pain, scrofula, swollen welling abscess, scalds.
TCMBANKHE005874 玳玳花 Oppression in chest due to glomus, distending pain in stomach duct and abdomen, vomiting, reduced food intake.
TCMBANKHE006099 桑白皮 Lung heat cough asthma, water-rheum collecting lung, distention fullness and rapid asthma, edema, beriberi, inhibited urination.
TCMBANKHE008310 Cortex Eucommiae 杜仲 To tonify the liver and the kidney, to strengthen the tendons and bones, and to prevent miscarrige./Hypertension, kidney vacuity lumbago, weakness in sinews and bones, stirring fetus in pregnancy.
TCMBANKHE008697 Caulis Aristolochiae seu Clematis 木通 1. To promote water metabolism and relieve abnormal urination; 2. To clear heat and promote lactation/Acute urethritis, short voidings of reddish urine, strangury-turbidity, edema, nephritis with edema, galactostasis, heat vexation in chest, throat pain, mouth sore, tongue sores, wind-damp impediment pain, galactostasis, amenorrhea, dysmenorrhea.
TCMBANKHE008167/YEM-39/XU-672 Cortex Eucommiae|Eucommia ulmoides Oliv.|Eucommia ulmoides 杜仲 杜仲 云南民族药物志:第一卷|贵州省岑巩县平庄镇师兆村 To tonify the liver and the kidney, to strengthen the tendons and bones, and to prevent miscarrige./Hypertension, kidney vacuity lumbago, weakness in sinews and bones, stirring fetus in pregnancy. 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族
TCMBANKHE007773/YEM-590/XU-716 Ramulus Mori|Morus alba L.|Morus alba 桑枝|桑 桑叶 云南民族药物志:第三卷|云南省昭通市盐津县 To relieve rheumatic arthralgia./Hypertension, aching pain in joints, numbness in joints. 阿昌族/布依族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/水族/佤族/彝族/藏族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000474 NCOA1 F-SRC-1; KAT13A; RIP160; SRC1; bHLHe42; bHLHe74 nuclear receptor coactivator 1
TCMBANKGE000476 NCOA2 GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75 nuclear receptor coactivator 2
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1