Compound Summary


  Compound Information

药名:

Isoscopoletin;6-Hydroxy-7-methoxy-2H-chromen-2-one;6-hydroxy-7-methoxy coumarin;6-hydroxy-7-methylcoumarin

别名:

6-Hydroxy-7-methoxy-2-benzopyrone; isoscopoletin ; 6-hydroxy-7-methoxychromen-2-one; Esculetin 7-methyl ether; 2H-1-Benzopyran-2-one, 6-hydroxy-7-methoxy-; 776-86-3; 6-hydroxy-7-methoxy-chromen-2-one; 7-Methyl esculetin; ST5331501; isoscopoletin; 6-hydroxy-7-methoxy-coumarin; NCGC00163577-01; AIDS026314; 6-Hydroxy-7-methoxycoumarin; 17795_FLUKA; AIDS-026314; EINECS 212-282-4; 7-Methoxyesculetin; 6-hydroxy-7-methoxy-2-chromenone

分子式:

C10H8O4

Smiles:

COC1=C(C=C2C=CC(=O)OC2=C1)O

成分:

HBIN031229;HBIN012408;HBIN012411;HBIN012413

OB_score:

23.457407

CAS_id:

776-86-3

SymMap_id:

SMIT02960

TCMID_id:

11699;36265;38713;10481

TCMSP_id:

MOL000339

PubChem_id:

69894


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE001170 猕猴桃根
TCMBANKHE001998 Calophyllum caledonicum
TCMBANKHE002732 蚕沙 1. Treatment of damp-heat obstruction syndrome. Silkworm excrement (Cansha) is used with Tetrandra root (Fangji), Coix seed (Yiyiren) and Talc (Huashi) in the formula Xuanbi Tang .2. Eczema. The decoction of the herb is used for external washing. 3. Treat
TCMBANKHE005380 Herba Euphorbiae humifusae 地锦草 To remove toxic heat and to arrest bleeding by reducing heat in blood./Dysentery, enteritis, hemoptysis, hematuria, hematochezia, flooding and spotting, swollen welling abscess, sore and boil.
TCMBANKHE005622 鸡矢藤 Wind-damp pain, diarrhea, dysentery, pain in stomach duct and abdomen, qi vacuity edema, heavy head and low food intake, liver spleen enlargement, scrofula, intestinal welling abscess, innominate toxin swelling, knocks and falls.
TCMBANKHE004404 Lignum Aquilariae Resitum 沉香 To promote the flow of qi and relieve pain, to arrest vomiting by warming the stomach, and to relieve asthma./Cold pain in stomach duct and abdomen, qi counterflow with asthma, stomach cold with retching counterflow, vacuity cold in lumbus and knees, vacuity constipation, qi strangury.
TCMBANKHE004459 Fructus Lycii 枸杞子 To benefit the liver and the kidney, to replenish vital essence and to improve eyesight./Lassitude in lumbus and knees, emission, dizziness and dim vision, lung disease with cough, diabetes mellitus.
TCMBANKHE004697 Radix Kansui 甘遂 To cause drastic purgation and expel the retained water./Edema, ascites, flowing rheum in chest, concretion conglomeration accumulation and gathering, epilepsy, cough and asthma, urinar y and fecal stoppage.
TCMBANKHE009004 Saussurea involucrata 雪莲 To warm kidney and invigorate yang , dispel wind and overcome damp, quicken blood and free menstruation./Impotence, weakness in lumbus and knees, wind-damp impediment pain, menstrual disorder, amenorrhea, uterus cold and abdominal pain, cold rheum cough.
TCMBANKHE006650 Lycium barbarum 宁夏枸杞子 See Lycium chinense./See Lycium chinense.
TCMBANKHE004788 Saussurea involucrata; Saussurea tridactyla var. maidugonla 雪莲 To warm kidney and invigorate yang , dispel wind and overcome damp, quicken blood and free menstruation./Impotence, weakness in lumbus and knees, wind-damp impediment pain, menstrual disorder, amenorrhea, uterus cold and abdominal pain, cold rheum cough.
TCMBANKHE005071 Herba Visci 槲寄生 To relieve rheumatic conditions, to replenish the liver and the kidney, to strengthen the tendons and the bones, and to prevent abortion./Hypertension, cerebral and cardiovascular diseases, wind-damp impediment pain, limp aching lumbus and knees, stirring fetus in pregnancy.
TCMBANKHE007973 Herba Artemisiae Scopariae 茵陈 To remove damp-heat and relieve jaundice./1. Its decoction or its volatile oil, and active components such as chlorogenic acid, caffeic acid and hydroxyacetophenone are chologogues.2. Protecting the liver of experimental animals from the damage of CCl4.3. Decreasing the level of blood lipids and alleviating artherosclerosis and lipidosis in rabbits.4. Increasing the coronary flow of rabbits in vitro.5. Its volatile oil inhibits the growth of Shigella dysenteriae, Hemolytic streptococcus and various dermatomyces in vitro.6. Anticoagulative.
TCMBANKHE008896 Buxus microphylla var. sinica 黄杨木叶 To clear heat and resolve toxin, dissipate binds and disperse swelling./Wind-damp impediment pain, qi distention in chest and abdomen, mounting qi , toothache, painful wound from knocks and falls.
TCMBANKHE007736/XU-619 Chloranthus japonicus 银线草 陕西城关镇 To quicken blood and move stasis, dispel wind and eliminate damp, resolve toxin./Knocks and falls, wind-damp impediment pain, wind-cold common cold, swelling toxin sores, poisonous snake bites.
TCMBANKHE007625 Radix Solani melongee 茄根
TCMBANKHE007962/YEM-204 Herba Violae|Viola yedoensis Makino 紫花地丁 紫花地丁 云南民族药物志:第一卷 To remove toxic heat, to reduce heat from blood and to induce subsidence of swelling./Welling abscess and flat abscess with clove sore, erysipelas, mumps, mammary welling abscess, intestinal welling abscess, scrofula, damp-heat diarrhea dysentery, jaundice, red eyes with gall, poisonous snake bites. 傈僳族/彝族
TCMBANKHE008264/YEM-551 Artemisia scoparia [Syn. Artemisia capillaris var. scoparia]|Artemisia capillaris Thunb. 黄蒿|茵陈蒿 茵陈 云南民族药物志:第三卷 See Artemisia capillaris./See Artemisia capillaris. 阿昌族/傣族/德昂族/景颇族/傈僳族/瑶族/彝族/藏族/壮族
TCMBANKHE006707/YEM-80 Dracaena cochinchinensis|Dracaena cochinchinensis (Lour.)S.C.Chen. 剑叶龙血树 剑叶龙血树 云南民族药物志:第一卷 To dissipate stasis and settle pain, stanch bleeding, close sores and engender flesh./Knocks and falls, internal damage stasis pain, dysmenorrhea, postpartum blood stasis abdominal pain, incessant bleeding, scrofula, ulcer of lower limb, hemorrhoids. 傣族/拉祜族
TCMBANKHE007056/YEM-9 Herba Lobeliae Chinensis|Lobelia chinensis Lour. 半边莲 半边莲 云南民族药物志:第一卷 To cause diuresis, and to remove toxic heat./Edema, edema and enlarged abdomen, edema in face and foot, swollen welling abscess and clove sores, snake or insect bites. 阿昌族/傣族/德昂族/景颇族/傈僳族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000221 GRIA2 GLUR2; GLURB; GluA2; GluR-K2; HBGR2; gluR-2; gluR-B glutamate ionotropic receptor AMPA type subunit 2
TCMBANKGE000425 DRD1 DADR; DRD1A dopamine receptor D1
TCMBANKGE000633 ADRB2 ADRB2R; ADRBR; B2AR; BAR; BETA2AR adrenoceptor beta 2
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001467 LTA4H - leukotriene A4 hydrolase
TCMBANKGE001755 MAOB - monoamine oxidase B
TCMBANKGE001818 NQO2 DHQV; DIA6; NMOR2; QR2 N-ribosyldihydronicotinamide:quinone reductase 2
TCMBANKGE005535 CHRM1 HM1; M1; M1R cholinergic receptor muscarinic 1
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE007924 PKIA PRKACN1 cAMP-dependent protein kinase inhibitor alpha
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1
TCMBANKGE014941 DPEP1 MBD1; MDP; RDP dipeptidase 1