Compound Summary

  Compound Information

TCMBANKIN061627

药名:	matairesinol
别名:	41328-88-5; AIDS030806; (-)-Matairesinol; Matairesinol; 3R,4R-Bis((4-hydroxy-3-methoxyphenyl)methyl)dihydro-2(3H)-furanone; AIDS-030806; (3R,4R)-3,4-bis[(4-hydroxy-3-methoxy-phenyl)methyl]tetrahydrofuran-2-one; ARTIGENIN CONGENER; (3R,4R)-3,4-bis(4-hydroxy-3-methoxy-benzyl)tetrahydrofuran-2-one; 580-72-3; DIBENZYLBUTYROLACTONE LIGNANOLIDE; (3R,4R)-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one; 40043_FLUKA; MEGxp0_001689; (3R,4R)-3,4-bis[(4-hydroxy-3-methoxy-phenyl)methyl]oxolan-2-one; Arbo 5; C10682; (3R,4R)-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-2-tetrahydrofuranone; (alphaR,betaR)-alpha,beta-Bis(4-hydroxy-3-methoxybenzyl)butyrolactone; ACon1_001075; 2(3H)-Furanone, dihydro-3,4-bis((4-hydroxy-3-methoxyphenyl)methyl)-, (3R-trans)-;(- )-matairesinol;MAX
分子式:	C20H22O6
Smiles:	COC1=C(C=CC(=C1)CC2COC(=O)C2CC3=CC(=C(C=C3)O)OC)O
成分:	HBIN034543;HBIN034571;HBIN034544
OB_score:	4.499311
CAS_id:	580-72-3
SymMap_id:	SMIT01505;SMIT03110
TCMID_id:	13587;34173
TCMSP_id:	MOL000537
PubChem_id:	119205

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE004204	Tsuga heterophylla	异叶铁杉
TCMBANKHE002499	Rhizoma Ahemones Daddeae	两头尖			To relieve rheumatic conditions, and to cure carbuncle./Treatment of rheumatoid arthritis with muscular contracture and joint pain, carbuncle with ulceration.
TCMBANKHE002688	Semen armeniacae amarum	苦杏仁			To relieve cough and asthma, and to relax bowels./Treatment of cough and asthma accompanied by stuffiness in the chest and profuse expectoration, constipation due to deficiency of blood and fluid.
TCMBANKHE003799	Fructus Forsythiae	连翘			To remove toxic heat, to cause subsidence of sweeling,and to eliminate modulation./Influenza in early stage, common cold in early stage, wind-heat common cold, encephalitis, hepatitis, tuberculosis, warm disease, heat strangury with inhibited pain, welling abscess, welling abscess and flat abscess, toxin swelling, scrofula, goiter and tuberculosis, throat impediment.
TCMBANKHE004000	Caulis Trachelospermi	络石藤			To dispel wind and remove obstruction from the channels and to remove heat from blood and cause subsidence of swelling./Wind-damp impediment pain, hypertonicity of sinews and vessels, aching in lumbus and knees, throat impediment, swollen welling abscess, knocks and falls.
TCMBANKHE005968	Cedrus atlantica	北非雪松
TCMBANKHE005731		石上柏			To clear heat and dampness, promote blood circulation and remove blood stasis: For jaundice of dampness-heat type and abdominal mass. Recently used for acute and chronic hepatitis, cirrhosis, cholecysitis, etc., also for diarrhea, desentery and leucorrhag
TCMBANKHE006341	Podocarpus spicatus	穗花罗汉松
TCMBANKHE006664/YNS-181/XU-60/XU-236	Fructus Arctii lappae|Arctium lappa L.|Arctium lappa	牛蒡子;大力子|牛蒡	牛蒡根	云南药材标准：第二册|西藏昌都市洛隆县	祛风清热，解毒消肿，力气通便。用于咽喉肿痛，牙龈肿痛，咳嗽痰稠，腹胀便秘，消渴；黄白带下，干血痨，产后少乳，风毒面肿，大头风，疮疡肿痛|To dispel wind-heat and relieve cough, to promote eruption, to counteract toxicity, and to soothe sore throat;Treament of cough and expectroation in influenza or upper respiratory infection, measles, rubella, sore throat, mumps, erysipelas, carbuncles and sores./Wind-heat common cold, cough with profuse phlegm, measles papules, wind papules, swelling pain in throat, epidemic parotitis;1. Its extract exerts a significant and prolonged effect of lowering blood sugar in rats.2. Mildly diuretic and laxative.3. An active component, arctiin, can induce tonic convulsion, feeble respiration and eventually paralysis in frogs, mice and rabbits. erysipelas, swollen welling abscess and sore toxin.
TCMBANKHE006892/YEM-215/XU-360	Wikstroemia indica|Wikstroemia indica (L.)C.A. Mey.	了哥王根|了哥王	了哥王	云南民族药物志：第二卷|广西崇左市天等县	To clear heat, disinhibit urine, resolve toxin, break accumulation and kill worms./Pertussis, rheumatic arthritis, leprosy, bronchial asthma, amebic dysentery, pneumonia, epidemic parotitis, edema, scrofula, toxin swelling of sores, swelling and pus of sores, knocks and falls.	傣族/德昂族/景颇族/傈僳族/苗族/瑶族/壮族
TCMBANKHE007082/YEM-232/XU-632	Pinus massoniana|Pinus armandi Franch.	马尾松叶|华山松|马尾松	华山松	云南民族药物志：第二卷|吉林省白山市抚松县	To dispel wind and dry damp, kill worms and relieve itch, quicken blood and quiet spirit./Wind-damp impediment pain, beriberi, damp sore, lichen, wind papule itching, knocks and falls, neurasthenia, chronic nephritis, hypertension, prevention of influenza and encephalitis B.	傈僳族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000121	KCNH2	ERG-1; ERG1; H-ERG; HERG; HERG1; Kv11.1; LQT2; SQT1	potassium voltage-gated channel subfamily H member 2
TCMBANKGE000137	PLAU	ATF; BDPLT5; QPD; UPA; URK; u-PA	plasminogen activator, urokinase
TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000286	GSK3B	-	glycogen synthase kinase 3 beta
TCMBANKGE000309	SCN5A	CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1	sodium voltage-gated channel alpha subunit 5
TCMBANKGE000360	CCNA2	CCN1; CCNA	cyclin A2
TCMBANKGE000474	NCOA1	F-SRC-1; KAT13A; RIP160; SRC1; bHLHe42; bHLHe74	nuclear receptor coactivator 1
TCMBANKGE000478	CHEK1	CHK1	checkpoint kinase 1
TCMBANKGE000633	ADRB2	ADRB2R; ADRBR; B2AR; BAR; BETA2AR	adrenoceptor beta 2
TCMBANKGE000701	ESR2	ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8	estrogen receptor 2
TCMBANKGE000766	ACHE	ACEE; ARACHE; N-ACHE; YT	acetylcholinesterase (Cartwright blood group)
TCMBANKGE000784	CALM3	CALM; CAM1; CAM2; CAMB; CPVT6; CaM; CaMIII; HEL-S-72; LQT16; PHKD; PHKD3	calmodulin 3
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000903	PTGS1	COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS	prostaglandin-endoperoxide synthase 1
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001185	PPARG	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma	peroxisome proliferator activated receptor gamma
TCMBANKGE001202	MAPK14	CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA	mitogen-activated protein kinase 14
TCMBANKGE001506	ADRA1B	ADRA1; ALPHA1BAR	adrenoceptor alpha 1B
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE006339	CA2	CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282	carbonic anhydrase 2
TCMBANKGE006933	DHRS4L2	SDR25C3	dehydrogenase/reductase 4 like 2
TCMBANKGE009758	PDE3A	CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB	phosphodiesterase 3A
TCMBANKGE010388	PPARD	FAAR; NR1C2; NUC1; NUCI; NUCII; PPARB	peroxisome proliferator activated receptor delta
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1
TCMBANKGE011544	IGHG1	-	immunoglobulin heavy constant gamma 1 (G1m marker)
TCMBANKGE014087	EPX	EPO; EPP; EPX-PEN; EPXD	eosinophil peroxidase