Compound Summary

  Compound Information

TCMBANKIN061661

药名:	Swertiaperennin
别名:	1,8-Dihydroxy-2,6-dimethoxyxanthen-9-one; 1,8-dihydroxy-2,6-dimethoxy-xanthen-9-one; Methylswertianin; 2-O-Methylswertianin; 1,8-dihydroxy-2,6-dimethoxy-xanthone; C10083; 1,8-dihydroxy-2,6-dimethoxy-9-xanthenone; 1,8-Dihydroxy-2,6-dimethoxy-9H-xanthen-9-one; 9H-Xanthen-9-one, 1,8-dihydroxy-2,6-dimethoxy- (9CI); BRN 1351740; Xanthen-9-one, 1,8-dihydroxy-2,6-dimethoxy-; 22172-17-4; 1,8-Dihydroxy-2,6-dimethoxyxanthone
分子式:	C15H12O6
Smiles:	COC1=C(C2=C(C=C1)OC3=CC(=CC(=C3C2=O)O)OC)O
成分:	HBIN045190; HBIN002110; HBIN006258
OB_score:	96.850084
CAS_id:	22172-17-4
SymMap_id:	SMIT09298
TCMID_id:	42804; 14724
TCMSP_id:	MOL007957
PubChem_id:	5281653

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE002286	Gentiana kochiana
TCMBANKHE004098	Herba Swertiae	青叶胆			To increase the flow of bile, and to remove heat and damp./Damp-heat jaundice, heat strangury with inhibited pain, damp-heat diarrhea dysentery, red and white vaginal discharge, influenza, malaria with fever, acute gastritis, acute pharyngolaryngitis, acute tonsillitis, acute conjunctivitis, allergic dermatitis.
TCMBANKHE006091	Swertia japonica	日本獐牙菜
TCMBANKHE009149	Swertia angustifolia	狭叶獐牙菜
TCMBANKHE003727/YEM-310	Brassica oleracea var. capitata|Brassica oleracea L. var. capitata L.	甘蓝|莲花白	莲花白	云南民族药物志：第二卷	To clear heat and disinhibit damp, dissipate binds and relieve pain, boost kidney and supplement vacuity./Damp-heat jaundice, pain from ulcer in digestive tract, stiffness in joints, vacuity detriment.	傣族
TCMBANKHE008188/YEM-310	Brassica oleracea var. capitata|Brassica oleracea L. var. capitata L.	甘蓝|莲花白	莲花白	云南民族药物志：第二卷	To clear heat and disinhibit damp, dissipate binds and relieve pain, boost kidney and supplement vacuity./Damp-heat jaundice, pain from ulcer in digestive tract, stiffness in joints, vacuity detriment.	傣族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000286	GSK3B	-	glycogen synthase kinase 3 beta
TCMBANKGE000360	CCNA2	CCN1; CCNA	cyclin A2
TCMBANKGE000474	NCOA1	F-SRC-1; KAT13A; RIP160; SRC1; bHLHe42; bHLHe74	nuclear receptor coactivator 1
TCMBANKGE000476	NCOA2	GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75	nuclear receptor coactivator 2
TCMBANKGE000478	CHEK1	CHK1	checkpoint kinase 1
TCMBANKGE000701	ESR2	ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8	estrogen receptor 2
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000903	PTGS1	COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS	prostaglandin-endoperoxide synthase 1
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001185	PPARG	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma	peroxisome proliferator activated receptor gamma
TCMBANKGE001202	MAPK14	CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA	mitogen-activated protein kinase 14
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE006339	CA2	CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282	carbonic anhydrase 2
TCMBANKGE009758	PDE3A	CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB	phosphodiesterase 3A
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1
TCMBANKGE011544	IGHG1	-	immunoglobulin heavy constant gamma 1 (G1m marker)
TCMBANKGE014941	DPEP1	MBD1; MDP; RDP	dipeptidase 1