Compound Summary


  Compound Information

药名:

hispidulin

别名:

447H887; 5,7,4'-trihydroxy-6-methoxyflavone; Dinatin; 6-methoxyapigenin; LS-173226; CTK8G0189; NSC 122415; BDBM50049395; UNII-N7F61604C2; B6959; 4H-1-Benzopyran-4-one,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-; hispidulin ; ACon1_000933; MLS000728540; NP-001963; ZINC5732241; 4',7-Trihydroxy-6-methoxyflavone; MCULE-3882973229; SCHEMBL514926; HMS3344G13; C10058; 4?,5,7-Trihydroxy-6-methoxyflavone; PubChem SID: 26725244; W1618; MolPort-001-740-838; NSC122415; KS-00001FKN; MEGxp0_000683; Hispidulin; Oprea1_873387; cid_5281628; methoxyapigenin; BRD-K72066874-001-01-0; Flavone,5,7-trihydroxy-6-methoxy-; TCMDC-123942; N7F61604C2; FT-0697687; 1447-88-7; Scutellarein 6-methyl ether; CCRIS 8484; HMS2223A03; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one; 6-methylscutellarein; HY-N1950; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one #; 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-chromen-4-one; 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxychromen-4-one; Flavone, 4',5,7-trihydroxy-6-methoxy-; SMR000445653; AN-49210; 4H-1-Benzopyran-4-one, 5, 7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-; 5,7-Dihydroxy-2-(4-hydroxy-phenyl)-6-methoxy-chromen-4-one; hispidulin(dinatin); AKOS004110694; NCGC00167728-02; 6-methoxy apigenin; 5,7,4''-Trihydroxy-6-methoxyflavone; HUL; 4CN-1206; DTXSID30162786; NCI60_000530; CS-6502; IHFBPDAQLQOCBX-UHFFFAOYSA-N; ST024778; 4H-1-BENZOPYRAN-4-ONE, 5,7-DIHYDROXY-2-(4-HYDROXYPHENYL)-6-METHOXY-; CHEBI:75902; AC1NQYRM; BG01592767; C-56393; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one; NCGC00167728-01; CHEMBL293776; NSC-122415; NCGC00169216-01; Q-100165; 6-O-Methylapigenin; 4H-1-Benzopyran-4-one,5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-; LMPK12111159; 4',5,7-Trihydroxy-6-methoxyflavone; Dinatin; NCI60_000530; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one; AIDS126680; NSC122415; MEGxp0_000683; 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4-chromenone; Hispidulin; ST024778; Oprea1_873387; 4H-1-BENZOPYRAN-4-ONE, 5,7-DIHYDROXY-2-(4-HYDROXYPHENYL)-6-METHOXY-; NSC 122415; ZINC00113457; 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-chromen-4-one; 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxychromen-4-one; Flavone, 4',5,7-trihydroxy-6-methoxy-; SMR000445653; AIDS-126680; ACon1_000933; 4H-1-Benzopyran-4-one, 5, 7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-; MLS000728540; 6-O-Methylapigenin; 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-chromone; 1447-88-7; C10058; Scutellarein 6-methyl ether; 4',5,7-Trihydroxy-6-methoxyflavone; 6-methoxyapigenin

分子式:

C16H12O6

Smiles:

COC1=C(C2=C(C=C1O)OC(=CC2=O)C3=CC=C(C=C3)O)O

成分:

HBIN029430; HBIN012514; HBIN024094

OB_score:

30.972053

CAS_id:

1447-88-7

SymMap_id:

SMIT15766; SMIT04104

TCMID_id:

9563

TCMSP_id:

MOL001735

PubChem_id:

5281628


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000538 Citrus sudachii 苏打其柑橘
TCMBANKHE001338 Herba Lagotidis 洪连
TCMBANKHE003063 Herba Plantaginis 车前草 To remove heat and to induce diureses, to promote expectoration, to reduce heat in blood and to counteract toxicity./Treatment of edema with oliguria, urinary infection with difficult painful urination, diarrhea caused by summer-damp, cough caused by phlegm-heat, spitting of blood, epistaxis, carbuncles and sores.
TCMBANKHE003148 天山雪莲
TCMBANKHE003728 Radix Glycyrrhizae 甘草 To reinforce the function of the spleen and replenish qi, to remove heat and counteract toxicity, to dispel phlegm and relieve cough, to alleviate spasmodic pain, and to moderate drug actions./1. Its decoction can inhibit intestinal smooth muscles of rabbins in vitro, but glycyrrhizin and glycyrrhetinic acid have no this effect.2. Possessing an adrenocorticomimetic effect.3. Its extract and glycyrrhizin exerts a detoxifying effect.4. Antitussive and antiasthmatic. 5. Glycyrrhizin has anti-inflammatory effect similar to hydrocortisone.
TCMBANKHE005497 Rhizoma Belamcandae 射干 To remove toxic heat, eliminate phlegm, and soothe the sore throat./Heat toxin and phlegm-fire stasis, swelling pain in throat, cough and asthma.
TCMBANKHE003943 Herba Cirsii Japonici;Radix Cirsii Japonici;Herba seu Radix Cirsii japonici 大蓟 To arrest bleeding by reducing heat in the blood, to remove blood stasis, and to promote the subsidence of swelling.;Treatment of epistaxis, spitting of blood, hematuria, hematochezia, abnormal uterine bleeding, traumatic bleeding, carbuncles and sores./1. Its decoction can lower blood pressure2. Inhibiting the growth of (a)-streptococcus3. Shortening the bleeding time.4. Anti-inflammatory5. Diuretic.
TCMBANKHE004315 Iva frutescens 依瓦菊
TCMBANKHE004410 Flourensia cernua 俯垂弗劳菊
TCMBANKHE004723 Salvia officinalis 药用丹参液
TCMBANKHE004788 Saussurea involucrata; Saussurea tridactyla var. maidugonla 雪莲 To warm kidney and invigorate yang , dispel wind and overcome damp, quicken blood and free menstruation./Impotence, weakness in lumbus and knees, wind-damp impediment pain, menstrual disorder, amenorrhea, uterus cold and abdominal pain, cold rheum cough.
TCMBANKHE004954 Glycyrrhiza glabra var. typica 欧亚甘草
TCMBANKHE005003 Digitalis lanata 毛花毛地黄 See Digitalis purpurea ./See Digitalis purpurea.
TCMBANKHE005210 Flos Inulae 旋覆花 To relieve cough, eliminate phlegm, promote diuresis, and arrest vomiting./1. Its alcoholic extract is a diuretic in experimental rabbits.2. The decoction inhibits the growth Staphylococcus aureus and pneumococcus in vitro.
TCMBANKHE005225 Millingtonia hortensis 姊妹树 To dispel wind and relieve itch, resolve toxin and kill worms, suppress cough and transform phlegm./Eczema, urticaria, ascariasis, cough of phlegm asthma, leptochroa.
TCMBANKHE005251 Clerodendron indicum 长管假茉莉 To eliminate inflammation and disinhibit urine, quicken blood and disperse swelling, dispel wind-damp./Urinary tract infection, cystitis, sprain from knocks and falls, wind-damp bone pain.
TCMBANKHE005363 Semen Plantaginis 车前子 To remove heat, to cause diuresis and eliminate damp, to relieve dysuria, to clear the eye, and to promote expectoration./1. Diuretic. 2. Expectorant and antitussive.
TCMBANKHE005379 Digitalis ferruginea 锈毛地黄
TCMBANKHE005434 Ambrosia hispida 粗硬毛豚草
TCMBANKHE007396 Flos Eriocauli 谷精草 To expel wind and heat and to clear the eye of corneal opacity./Distended red eyes and screen, delacrimation and photophobia, night blindness, headache, deep-source nasal congestion, throat impediment, toothache, wind papule itching.
TCMBANKHE007721 Exocarpium Benincasae 冬瓜皮 1. To promote diuresis to relieve edema. 2. To clear summer-heat./Edema, inhibited urination [=dysuria], diarrhea, swelling of sores.
TCMBANKHE006352 Abrus Precatorius L. 相思子 Vomiting, welling abscess, parotitis, scab and lichen, wind-damp bone pain.
TCMBANKHE008738 Helenium autumnale 堆心菊
TCMBANKHE008977 Scutellaria przewalskii 艾叶黄芩
TCMBANKHE008042 Clerodendron fragrans 臭茉莉 To dispel wind and eliminate damp, quicken blood and disperse swelling./Wind-damp bone pain, beriberi, edema, hemorrhoids, prolapse of rectum, itchy papules, scab sore, chronic medullitis.
TCMBANKHE007252 Nepeta hindostana 印度假荆芥
TCMBANKHE007803 Herba Scutellariae barbatae 半枝莲 To remove toxic heat, and to cause diuresis./Heat toxin swollen welling abscess, throat pain, pulmonary welling abscess, intestinal welling abscess, scrofula, poisonous snake bite, knocks and falls, blood ejection, spontaneous external bleeding, blood strangury, edema, ascites, carcinoma.
TCMBANKHE008359 Semen Oroxyli 木蝴蝶 To remove heat from the lung and relieve sore throat, and to regulate the flow of qi of the liver and the stomach./Lung heat cough, throat impediment, aphonia, liver stomach qi pain.
TCMBANKHE008517 Folium Artemisiae Argyi 艾叶 1. To warm the channels and stop bleeding. 2. To dispel cold and stop pain/Cold pain in abdomen, menstrual disorder due to cold, infertility due to uterus cold, blood ejection, spontaneous external bleeding, flooding and spotting, fetal spotting, itchy skin.
TCMBANKHE009004 Saussurea involucrata 雪莲 To warm kidney and invigorate yang , dispel wind and overcome damp, quicken blood and free menstruation./Impotence, weakness in lumbus and knees, wind-damp impediment pain, menstrual disorder, amenorrhea, uterus cold and abdominal pain, cold rheum cough.
TCMBANKHE006892/YEM-215/XU-360 Wikstroemia indica|Wikstroemia indica (L.)C.A. Mey. 了哥王根|了哥王 了哥王 云南民族药物志:第二卷|广西崇左市天等县 To clear heat, disinhibit urine, resolve toxin, break accumulation and kill worms./Pertussis, rheumatic arthritis, leprosy, bronchial asthma, amebic dysentery, pneumonia, epidemic parotitis, edema, scrofula, toxin swelling of sores, swelling and pus of sores, knocks and falls. 傣族/德昂族/景颇族/傈僳族/苗族/瑶族/壮族
TCMBANKHE006476/YEM-509 Papaver somniferum|Papaver somniferum L. 鸦片|罂粟 罂粟 云南民族药物志:第三卷 To relieve pain, astringe intestines, suppress cough./Pain in heart and abdomen, chronic diarrhea, chronic dysentery, dry cough without phlegm. 傣族/基诺族/佤族/彝族
TCMBANKHE003999/YEM-687 Salvia plebeia|Salvia plebeia R.Br. 荔枝草 荔枝草 云南民族药物志:第四卷 To clear heat and resolve toxin, cool blood and dissipate stasis, disinhibit water and disperse edema./Common cold with fever, swelling pain in throat, lung heat cough, hemoptysis, blood ejection, hematuria, flooding and spotting, bleeding from hemorrhoids, nephritis with edema, white turbidity, dysentery, swelling toxin of welling abscess and sore, eczema titillation, knocks and falls, snake or insect bites. 傈僳族
TCMBANKHE005203/YEM-999/XU-341 Radix Isatidis seu Baphicacanthi|Isatis indigotica Fort.|Isatis indigotica 板蓝根|菘蓝 板蓝根 云南民族药物志:第五卷|山东省菏泽市 To remove toxic heat, to reduce heat in blood, and to soothe sore throat./Epidemic encephalitis, measles papulis, parotitis, influenza, warm toxin macular eruption, ardent fever with headache, massive head scourge, throat pain, maculopapular eruption, epidemic parotitis, erysipelas, hepatitis, swelling toxin of sore and welling abscess. 回族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000148 USP51 - ubiquitin specific peptidase 51
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000474 NCOA1 F-SRC-1; KAT13A; RIP160; SRC1; bHLHe42; bHLHe74 nuclear receptor coactivator 1
TCMBANKGE000476 NCOA2 GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75 nuclear receptor coactivator 2
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000585 BCL2L11 BAM; BIM; BOD BCL2 like 11
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000766 ACHE ACEE; ARACHE; N-ACHE; YT acetylcholinesterase (Cartwright blood group)
TCMBANKGE000784 CALM3 CALM; CAM1; CAM2; CAMB; CPVT6; CaM; CaMIII; HEL-S-72; LQT16; PHKD; PHKD3 calmodulin 3
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001011 TNFSF10 APO2L; Apo-2L; CD253; TL2; TNLG6A; TRAIL TNF superfamily member 10
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001112 PRKAB1 AMPK; HAMPKb protein kinase AMP-activated non-catalytic subunit beta 1
TCMBANKGE001127 PRKAA1 AMPK; AMPKa1 protein kinase AMP-activated catalytic subunit alpha 1
TCMBANKGE001128 PRKAA2 AMPK; AMPK2; AMPKa2; PRKAA protein kinase AMP-activated catalytic subunit alpha 2
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1
TCMBANKGE011544 IGHG1 - immunoglobulin heavy constant gamma 1 (G1m marker)
TCMBANKGE012594 RHO CSNBAD1; OPN2; RP4 rhodopsin
TCMBANKGE014941 DPEP1 MBD1; MDP; RDP dipeptidase 1