Compound Summary


  Compound Information

药名:

oroxylin

别名:

5,7-dihydroxy-6-methoxy-2-phenyl-4H-chromen-4-one; CTK1D7949; ZINC5998558; Oroxylin A; CHEMBL183513; 5,7-Dihydroxy-6-methoxy-2-phenyl-chromen-4-one; SC-69298; NP-005013; HY-N0560; MolPort-019-937-219; 5,7-dihydroxy-6-methoxy-2-phenyl-4H-1-benzopyran-4-one; AKOS015903364; Oroxylin-A; MFCD02259441; UNII-53K24Z586G; 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one; 6-Methoxybaicalein;; FT-0688332; Oroxylin A, >=98% (HPLC); CHEBI:61668; 5,7-dihydroxy-6-methoxyflavone; BDBM50430091; AC1NSZBG; 4H-1-Benzopyran-4-one, 5,7-dihydroxy-6-methoxy-2-phenyl-; 5,7-Dihydroxy-6-methoxyflavone;; Y0150; I14-19006; baicalein 6-methyl ether; 53K24Z586G; DTXSID70197375; Baicalein 6-methyl ether;6-Methoxybaicalein; 480-11-5; SCHEMBL431423; LMPK12111096; Oroxylin; CS-4948

分子式:

C16H12O5

Smiles:

COC1=C(C2=C(C=C1O)OC(=CC2=O)C3=CC=CC=C3)O

成分:

HBIN038302

OB_score:

41.367569

CAS_id:

480-11-5

SymMap_id:

SMIT18852;SMIT00521;SMIT18725

TCMID_id:

25399;16205;24904

TCMSP_id:

MOL002928

PubChem_id:

5320315


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE001741 黄芩子
TCMBANKHE003734 radix tripterygii wilfordii 雷公藤 To expel wind-dampness, relieve swelling, alleviate pain and dredge the meridian passage./Rheumatoid arthritis, rheumatic arthritis, glomerulonephritis, nephropathy syndrome, erythematous lupus, dryness in eyes and mouth, Behcet’s syndrome, psoriasis, eczema, leprosy, scab sore, intractable lichen.
TCMBANKHE003746 Radix Scutellariae 黄芩 To remove damp-heat, to quench fire and counteract toxicity, to arrest bleeding, and to prevent abortion./Chest oppression with retching, diarrhea, jaundice, lung heat cough, infection of upper respiratory tract, acute tonsillitis, acute pharyngolaryngitis, ardent fever with vexation and thirst, blood heat, blood ejection, spontaneous external bleeding, swelling toxin of welling abscess and sore, stirring fetus in pregnancy.
TCMBANKHE005914 Scutellaria likiangensis 丽江黄芩 See Scutellaria baicalensis./See Scutellaria baicalensis.
TCMBANKHE004192 黄芩
TCMBANKHE005975 Scutellaria hypericifolia 川黄芩 See Scutellaria baicalensis./See Scutellaria baicalensis.
TCMBANKHE004404 Lignum Aquilariae Resitum 沉香 To promote the flow of qi and relieve pain, to arrest vomiting by warming the stomach, and to relieve asthma./Cold pain in stomach duct and abdomen, qi counterflow with asthma, stomach cold with retching counterflow, vacuity cold in lumbus and knees, vacuity constipation, qi strangury.
TCMBANKHE004980 Bupleurum scorzonerifolium 红柴胡 See Bupleurum chinense./See Bupleurum chinense.
TCMBANKHE005123 Scutellaria viscidula 粘毛黄芩 See Scutellaria baicalensis./See Scutellaria baicalensis.
TCMBANKHE005940 Vitex rotundifolia [Syn. Vitex trifollia var. simplicifolia ] 单叶蔓荆
TCMBANKHE008381 Scutellaria rehderiana 甘肃黄芩 See Scutellaria baicalensis./See Scutellaria baicalensis.
TCMBANKHE006914 Ramulus Euonymi 鬼箭羽 For activating blood and modulating period/Concretion and conglomeration, pain in heart and abdomen, amenorrhea, dysmenorrhea, postpartum stasis stagnation abdominal pain, retention of lochia, mounting qi , joint running impediment pain, swelling of sores, painful wound from knocks and falls, burns and scalds, poisonous snake bite.
TCMBANKHE008359 Semen Oroxyli 木蝴蝶 To remove heat from the lung and relieve sore throat, and to regulate the flow of qi of the liver and the stomach./Lung heat cough, throat impediment, aphonia, liver stomach qi pain.
TCMBANKHE005979/YNS-177/YEM-122/XU-155 Oroxylum indicum|Oroxylum indicum (L.)Vent. 木瑚蝶树皮|木蝴蝶|千张纸 木蝴蝶树皮|木蝴蝶 云南药材标准:第三册|云南民族药物志:第一卷|云南省普洱市江城县国庆乡和平村弄扎河小组 清热利湿退黄;利咽消肿。主传染性黄疽肝炎;咽喉肿痛|To clear heat and disinhibit damp, abate jaundice, disinhibit throat and disperse swelling./Infective hepatitis, swelling pain in throat. 傣族/哈尼族/基诺族/拉祜族/傈僳族/佤族/彝族/藏族
TCMBANKHE007748/YEM-22/XU-390 Herba andrographitis|Andrographis paniculata (Burm. f,)Nees|Andrographis paniculata 穿心莲 穿心莲 云南民族药物志:第一卷|云南省普洱市镇沅县 1. To clear heat and release toxins; 2. To dry dampness/Infection of upper respiratory tract, fever, wind-heat common cold, bacillary dysentery, diarrhea, tonsillitis, pneumonia, tuberculosis, lung heat cough, pulmonary welling abscess, postlithotripsy urinary tract infection, warm disease fever, pertussis, swelling pain in throat, damp-heat jaundice, strangury syndrome, erysipelas, sore and welling abscess, eczema, poisonous snake bite. 阿昌族/傣族/德昂族/景颇族/傈僳族
TCMBANKHE003759/YNS-62/YEM-852/XU-165 Scutellaria amoena|Scutellaria amoena C. H. Wright|Scutellaria amoena C.H.Wright 滇黄芩 滇黄芩 云南药材标准:第七册|云南民族药物志:第五卷|云南省昆明市盘龙区茨坝长虫山 清热燥湿,泻火解毒,止血,安胎。用于湿温、暑湿,胸闷呕恶,湿热痞满,泻痢,黄疸,肺热咳嗽,高热烦渴,血热吐衄,痈肿疮毒,胎动不安。|See Scutellaria baicalensis./See Scutellaria baicalensis. 布依族/德昂族/傈僳族/苗族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000139 POR CPR; CYPOR; P450R cytochrome p450 oxidoreductase
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000236 BDNF ANON2; BULN2 brain derived neurotrophic factor
TCMBANKGE000264 ABCB1 ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1 ATP binding cassette subfamily B member 1
TCMBANKGE000276 NOS1 IHPS1; N-NOS; NC-NOS; NOS; bNOS; nNOS nitric oxide synthase 1
TCMBANKGE000849 HK2 HKII; HXK2 hexokinase 2
TCMBANKGE001037 MMP2 CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1 matrix metallopeptidase 2
TCMBANKGE001076 SOD2 GClnc1; IPO-B; IPOB; MNSOD; MVCD6; Mn-SOD superoxide dismutase 2
TCMBANKGE001094 SIRT3 SIR2L3 sirtuin 3
TCMBANKGE001107 NOS3 ECNOS; eNOS nitric oxide synthase 3
TCMBANKGE001114 IL6 BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6 interleukin 6
TCMBANKGE001118 MMP9 CLG4B; GELB; MANDP2; MMP-9 matrix metallopeptidase 9
TCMBANKGE001131 CASP9 APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 caspase 9
TCMBANKGE001156 CASP3 CPP32; CPP32B; SCA-1 caspase 3
TCMBANKGE001166 BCL2 Bcl-2; PPP1R50 BCL2 apoptosis regulator
TCMBANKGE001177 TP53 BCC7; BMFS5; LFS1; P53; TRP53 tumor protein p53
TCMBANKGE001197 FOS AP-1; C-FOS; p55 Fos proto-oncogene, AP-1 transcription factor subunit
TCMBANKGE002980 CHEK2 CDS1; CHK2; HuCds1; LFS2; PP1425; RAD53; hCds1 checkpoint kinase 2
TCMBANKGE006373 TYW1 RSAFD1; TYW1A; YPL207W tRNA-yW synthesizing protein 1 homolog
TCMBANKGE007151 TIMP2 CSC-21K; DDC8 TIMP metallopeptidase inhibitor 2
TCMBANKGE007799 FLT3 CD135; FLK-2; FLK2; STK1 fms related receptor tyrosine kinase 3
TCMBANKGE009863 MTRR MSR; cblE 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
TCMBANKGE010043 PPIF CYP3; CyP-M; Cyp-D; CypD peptidylprolyl isomerase F
TCMBANKGE011356 NDOR1 CIAE1; NR1; bA350O14.9 NADPH dependent diflavin oxidoreductase 1