Compound Summary

  Compound Information

TCMBANKIN061677

药名:	Cepharanone B
别名:	Aristololactam bii; 37326-16-2; Dibenz[cd,f]indol-4(5H)-one, 1,2-dimethoxy-; Dibenz(cd,f)indol-4(5H)-one, 1,2-dimethoxy-; cepharanone b; 53948-09-7; AIDS224741; AIDS-224741
分子式:	C17H13NO3
Smiles:	COC1=C(C2=C3C(=C1)C(=O)NC3=CC4=CC=CC=C42)OC
成分:	HBIN020123;HBIN016766;HBIN016817
OB_score:	21.805698
CAS_id:	37326-16-2
SymMap_id:	SMIT08502;SMIT14372
TCMID_id:	35615;1695
TCMSP_id:	MOL006975
PubChem_id:	162739

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE003735	Herba Houttuyniae	鱼腥草			To remove toxic heat, to promote the drainage of pus, and to relieve dysuria./Pulmonary welling abscess with hacking of pus and blood, lung heat phlegm cough, pneumonia, chronic bronchitis, urinary tract infection, odynuria, chronic uterine cervical infection, leptospirosis, otitis media, cystitis, dysentery, mastitis, heat toxin sores, heat strangury.
TCMBANKHE004037	Rhizoma seu Herba Saururi	三白草			To remove toxic heat, and cause diuresis./Edema, beriberi, jaundice, strangury-turbidity, vaginal discharge, swollen welling abscess, clove sore.
TCMBANKHE004587	Piper taiwanense	台湾胡椒
TCMBANKHE007483	Annona squamosa	番荔枝			To supplement stomach and spleen, clear heat and resolve toxin, kill worms./Malign sore and swelling toxin, intestinal parasitic disease.
TCMBANKHE006163	Lignum Pini Nodi	松节			1. To dispel wind and dry dampness; 2. To stop pain/Treatment of: 1. Wind-damp obstruction syndrome. Pine nodular branch (Songjie) is used with herbs that dispel wind and dampness. In acute arthritis with severe pain, Pine nodular branch (Songjie) is soaked in wine for drinking. 2. External injury pain. Pi
TCMBANKHE006566	Cortex Moutan	牡丹皮			To remove heat from blood, to activate blood circulation and eliminate blood stasis./Appendicitis, dysentery, hypertension, allergic rhinitis, warm heat disease with fever, macular eruption, blood ejection, spontaneous external bleeding, steaming bone tidal fever due to yin vacuity, amenorrhea due to blood stasis, dysmenorrhea, concretion and conglomeration, swelling toxin of welling abscess and sore, painful wound from knocks and falls, wind-damp-heat impediment.
TCMBANKHE007928		白药子			Septicemia, acute hepatitis, bacillary dysentery, parotitis, neurodermatitis, swelling pain in throat, heat toxin swollen welling abscess, wind-damp impediment pain, abdominal pain and diarrhea, blood ejection, bleeding, spontaneous external bleeding, bleeding due to external injury.

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000286	GSK3B	-	glycogen synthase kinase 3 beta
TCMBANKGE000309	SCN5A	CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1	sodium voltage-gated channel alpha subunit 5
TCMBANKGE000478	CHEK1	CHK1	checkpoint kinase 1
TCMBANKGE000701	ESR2	ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8	estrogen receptor 2
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000903	PTGS1	COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS	prostaglandin-endoperoxide synthase 1
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001202	MAPK14	CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA	mitogen-activated protein kinase 14
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE009294	HTR3A	5-HT-3; 5-HT3A; 5-HT3R; 5HT3R; HTR3	5-hydroxytryptamine receptor 3A
TCMBANKGE014050	GABRA1	ECA4; EIEE19; EJM; EJM5	gamma-aminobutyric acid type A receptor subunit alpha1