Compound Summary
Compound Information
药名: | Nornuciferine;n-nornuciferine;daechualkoloid A;(s)-nornuciferine |
别名: | NORAPORPHINE, 1,2-DIMETHOXY-; dl-Nornuciferine; 1,2-Dimethoxynoraporphine; 4H-Dibenzo(de,g)quinoline, 5,6,6a,7-tetrahydro-1,2-dimethoxy-, (+-)- (9CI); nornuciferine; 54750-04-8 |
分子式: | C18H19NO2 |
Smiles: | COC1=C(C2=C3C(CC4=CC=CC=C42)NCCC3=C1)OC |
成分: | HBIN037367;HBIN037169;HBIN022544;HBIN044236 |
OB_score: | 22.631326;22.525788 |
CAS_id: | 54750-04-8;4846-19-9 |
SymMap_id: | SMIT08510;SMIT00685 |
TCMID_id: | 33016;15772;34950;15771 |
TCMSP_id: | MOL006986;MOL007216 |
PubChem_id: | 41169;12313579 |
化合物对应的植物
| 植物ID | 拉丁名 | 药用植物名 | 药名 | 来源 | 功能与主治 | 使用民族 |
|---|
| TCMBANKHE004632 | Nelumbo lutea | 金黄连 | ||||
| TCMBANKHE002277 | 荷花 | |||||
| TCMBANKHE004062 | Moschus moschiferus, Moschus berezovskii, Moschus sifanicus | 麝香 | To open orifices and arouse spirit, quicken blood and dissipate binds, disperse swelling and relieve pain./Angina pectoris, cerebral thrombosis, vascular migraine, carcinoma, febrile diseases clouded spirit, wind stroke with phlegm reversal, qi depression and fulminant reversal, malignity stroke stupor, amenorrhea due to blood stasis, concretion conglomeration accumulation and gathering, sudden pain in heart and abdomen, knocks and falls, wound, impediment pain numbness, malign sore with welling abscess and flat abscess, throat impediment, mouth sore, gan of teeth and gum, otitis media. | |||
| TCMBANKHE004608 | Magnolia grandiflora | 荷花玉兰 | To dispel wind and dissipate cold, move qi and relieve pain./Externally contracted wind-cold, headache and nasal congestion, distending pain in stomach duct, vomiting and diarrhea, hypertension, tuberculosis. | |||
| TCMBANKHE004636 | Fructus Zizyphi Jujubae | 大枣 | To tonify the spleen and replenish qi, to nourish blood, and to ease the mind./Reduced food intake due to spleen vacuity, lack of strength and sloppy stool, visceral agitation. | |||
| TCMBANKHE004791 | Herba Spirodelae | 浮萍 | To dispel wind-heat, to promote eruption, and to cause diuresis./Wind-heat exterior syndrome, non-eruption of measles, dormant papules with pruritus, edema, dribbling urinary block, sore and lichen, erysipelas, scalds. | |||
| TCMBANKHE008178 | Annona glabra | 圆滑番荔枝 | ||||
| TCMBANKHE007928 | 白药子 | Septicemia, acute hepatitis, bacillary dysentery, parotitis, neurodermatitis, swelling pain in throat, heat toxin swollen welling abscess, wind-damp impediment pain, abdominal pain and diarrhea, blood ejection, bleeding, spontaneous external bleeding, bleeding due to external injury. | ||||
| TCMBANKHE008341 | Fructus Zizyphi Jujubae | 大枣 | To tonify the spleen and replenish qi, to nourish blood, and to ease the mind./Reduced food intake due to spleen vacuity, lack of strength and sloppy stool, visceral agitation. | |||
| TCMBANKHE005257/YEM-104 | Folium Nelumbinis|Nelumbo nucifera Gaertn. | 荷叶|莲 | 莲 | 云南民族药物志：第一卷 | To relieve summer-heat, to invigorate the spleen function of the spleen and arrest bleeding by reducing heat in blood./Summerheat-heat vexation and thirst, summerheat-damp diarrhea, spleen vacuity diarrhea, blood heat, blood ejection, spontaneous external bleeding, hematochezia, flooding and spotting. | 阿昌族/傣族/德昂族/景颇族/傈僳族/彝族/藏族 |
| TCMBANKHE006652/YEM-104 | Nelumbo nucifera|Nelumbo nucifera Gaertn. | 莲子|莲 | 莲 | 云南民族药物志：第一卷 | To supplement spleen and check diarrhea, boost kidney and secure essence, nourish heart and quiet spirit./Chronic diarrhea, inappetence, emission, restlessness, fright palpitation, insomnia, flooding and spotting, excessive leukorrhea. | 阿昌族/傣族/德昂族/景颇族/傈僳族/彝族/藏族 |
植物对应的疾病
| 疾病ID | 病名 | 疾病类型 | MeSH | 参考文献 |
|---|
化合物对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE000181 | PIM1 | PIM | Pim-1 proto-oncogene, serine/threonine kinase |
| TCMBANKGE000201 | ESR1 | ER; ESR; ESRA; ESTRR; Era; NR3A1 | estrogen receptor 1 |
| TCMBANKGE000205 | NOS2 | HEP-NOS; INOS; NOS; NOS2A | nitric oxide synthase 2 |
| TCMBANKGE000286 | GSK3B | - | glycogen synthase kinase 3 beta |
| TCMBANKGE000309 | SCN5A | CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 | sodium voltage-gated channel alpha subunit 5 |
| TCMBANKGE000360 | CCNA2 | CCN1; CCNA | cyclin A2 |
| TCMBANKGE000478 | CHEK1 | CHK1 | checkpoint kinase 1 |
| TCMBANKGE000633 | ADRB2 | ADRB2R; ADRBR; B2AR; BAR; BETA2AR | adrenoceptor beta 2 |
| TCMBANKGE000701 | ESR2 | ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 | estrogen receptor 2 |
| TCMBANKGE000766 | ACHE | ACEE; ARACHE; N-ACHE; YT | acetylcholinesterase (Cartwright blood group) |
| TCMBANKGE000813 | DPP4 | ADABP; ADCP2; CD26; DPPIV; TP103 | dipeptidyl peptidase 4 |
| TCMBANKGE000903 | PTGS1 | COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS | prostaglandin-endoperoxide synthase 1 |
| TCMBANKGE000938 | CDK2 | CDKN2; p33(CDK2) | cyclin dependent kinase 2 |
| TCMBANKGE000965 | CHRNA7 | CHRNA7-2; NACHRA7 | cholinergic receptor nicotinic alpha 7 subunit |
| TCMBANKGE001073 | PTGS2 | COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 | prostaglandin-endoperoxide synthase 2 |
| TCMBANKGE001202 | MAPK14 | CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA | mitogen-activated protein kinase 14 |
| TCMBANKGE001506 | ADRA1B | ADRA1; ALPHA1BAR | adrenoceptor alpha 1B |
| TCMBANKGE001943 | ADRA1D | ADRA1; ADRA1A; ADRA1R; ALPHA1; DAR; dJ779E11.2 | adrenoceptor alpha 1D |
| TCMBANKGE003625 | SLC6A4 | 5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT | solute carrier family 6 member 4 |
| TCMBANKGE004266 | AR | AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM | androgen receptor |
| TCMBANKGE005535 | CHRM1 | HM1; M1; M1R | cholinergic receptor muscarinic 1 |
| TCMBANKGE006943 | CHRM3 | EGBRS; HM3; PBS | cholinergic receptor muscarinic 3 |
| TCMBANKGE008702 | OPRM1 | LMOR; M-OR-1; MOP; MOR; MOR1; OPRM | opioid receptor mu 1 |
| TCMBANKGE008921 | RXRA | NR2B1 | retinoid X receptor alpha |
| TCMBANKGE009294 | HTR3A | 5-HT-3; 5-HT3A; 5-HT3R; 5HT3R; HTR3 | 5-hydroxytryptamine receptor 3A |
| TCMBANKGE009455 | CHRM5 | HM5 | cholinergic receptor muscarinic 5 |
| TCMBANKGE009557 | PTPRCAP | CD45-AP; LPAP | protein tyrosine phosphatase receptor type C associated protein |
| TCMBANKGE009758 | PDE3A | CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB | phosphodiesterase 3A |
| TCMBANKGE011923 | CHRM4 | HM4; M4R | cholinergic receptor muscarinic 4 |
| TCMBANKGE012155 | SLC6A3 | DAT; DAT1; PKDYS; PKDYS1 | solute carrier family 6 member 3 |
| TCMBANKGE014050 | GABRA1 | ECA4; EIEE19; EJM; EJM5 | gamma-aminobutyric acid type A receptor subunit alpha1 |
| TCMBANKGE014423 | ADRA1A | ADRA1C; ADRA1L1; ALPHA1AAR | adrenoceptor alpha 1A |
| TCMBANKGE014625 | OPRD1 | DOP; DOR; DOR1; OPRD | opioid receptor delta 1 |
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