Compound Summary


  Compound Information

药名:

Jaranol

别名:

4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-3,7-dimethoxy-; Flavone, 4',5-dihydroxy-3,7-dimethoxy-; 5-hydroxy-2-(4-hydroxyphenyl)-3,7-dimethoxy-4-chromenone; AIDS039056; ACon1_000321; MEGxp0_000177; 5-hydroxy-2-(4-hydroxyphenyl)-3,7-dimethoxy-chromen-4-one; 3301-49-3; Kumatakenin; 5-hydroxy-2-(4-hydroxyphenyl)-3,7-dimethoxychromen-4-one; 5-hydroxy-2-(4-hydroxyphenyl)-3,7-dimethoxy-chromone; AIDS-039056; Flavone, 4',5-dihydroxy-3,7-dimethoxy-; BJBUTJQYZDYRMJ-UHFFFAOYSA-N; UNII-5FAQ11412T; Jaranol; 5-hydroxy-2-(4-hydroxyphenyl)-3,7-dimethoxy-chromen-4-one; SCHEMBL3351483; ZINC5732364; NCGC00169188-01; ACon1_000321; MolPort-001-740-355; 4CN-1330; DTXSID90186645; AC1NSXDF; CHEMBL349724; AKOS032948397; MEGxp0_000177; Kumatakenin; 3301-49-3; 5,4'-dihydroxy-3,7-dimethoxyflavone; Kumatakillin; Kaempferol 3,7-dimethyl ether; 5FAQ11412T; 5-Hydroxy-2-(4-hydroxyphenyl)-3,7-dimethoxy-4H-chromen-4-one #; 4H-1-Benzopyran-4-one,5-hydroxy-2-(4-hydroxyphenyl)-3,7-dimethoxy-; 4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-3,7-dimethoxy-; 4',5-Dihydroxy-3,7-dimethoxyflavone; LMPK12112690; 3,7-Di-O-methyl kaempferol; 5-hydroxy-2-(4-hydroxyphenyl)-3,7-dimethoxychromen-4-one; kumatakenin

分子式:

C17H14O6

Smiles:

COC1=CC(=C2C(=C1)OC(=C(C2=O)OC)C3=CC=C(C=C3)O)O

成分:

HBIN031446;HBIN032348

OB_score:

50.828817

CAS_id:

3301-49-3

SymMap_id:

SMIT02882;SMIT01477

TCMID_id:

12327

TCMSP_id:

MOL000239

PubChem_id:

5318869


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000767 Fructus Amomi Rotundus 豆蔻 To resolve damp, to remove stagnancy of food, and to promote digestion./Treatment of loss of appetite due to accumulation of turbid damp in the spleen and stomach, feeling of suffocation in the chest with anorexia at the early stage of damp-warm syndromes, nausea, vomiting, distension and pain in the chest and abdomen caused
TCMBANKHE001634 Fructus Choerospondiatis 广枣 To promote the flow of qi and blood, to replenish the heart and allay excitement./Treatment of stagnation of qi and blood with pectoral pain, palpitation and shortness of breath, uneasiness in mind.
TCMBANKHE003728 Radix Glycyrrhizae 甘草 To reinforce the function of the spleen and replenish qi, to remove heat and counteract toxicity, to dispel phlegm and relieve cough, to alleviate spasmodic pain, and to moderate drug actions./1. Its decoction can inhibit intestinal smooth muscles of rabbins in vitro, but glycyrrhizin and glycyrrhetinic acid have no this effect.2. Possessing an adrenocorticomimetic effect.3. Its extract and glycyrrhizin exerts a detoxifying effect.4. Antitussive and antiasthmatic. 5. Glycyrrhizin has anti-inflammatory effect similar to hydrocortisone.
TCMBANKHE003743 Radix Astragali 黄芪 To reinoforce qi and invigorate the function of the spleen./Common cold, influenza, chronic wound ulcer, chronic glomerulonephritis, diabetes mellitus due to internal heat, qi vacuity edema, chronic gastritis, qi vacuity and hypodynamia, reduced food intake and sloppy stool, center qi fall, chronic diarrhea, prolapse of rectum, hematochezia, flooding and spotting, spontaneous sweating due to exterior vacuity.
TCMBANKHE003940 Herba Elsholtziae;Haichow Elsholtzia;Mosla chinensis 香薷 1. To promote diaphoresis and release the exterior; 2. To resolve dampness and harmonize the spleen and stomach; 3. To promote water metabolism and release edema/Fever, aversion of cold, headache, absence of sweating, abdominal pain, vomiting and diarrhea, edema and inhibited urination, beriberi.
TCMBANKHE005027 苦楝皮 Ascariasis, oxyuria disease, abdominal pain due to worm accumulation, scab and lichen with itching.
TCMBANKHE007396 Flos Eriocauli 谷精草 To expel wind and heat and to clear the eye of corneal opacity./Distended red eyes and screen, delacrimation and photophobia, night blindness, headache, deep-source nasal congestion, throat impediment, toothache, wind papule itching.
TCMBANKHE006165 Rhizoma Dioscoreae bulbiferae 黄药子 To remove phlegm, disperse the lumps, detoxify and relieve swelling. /Goiter and tuberculosis, throat impediment, swelling toxin of welling abscess and sore, poisonous snake bite, carcinoma, blood ejection, spontaneous external bleeding, hemoptysis, pertussis, lung heat cough.
TCMBANKHE008166 Microtoena prainiana 南川冠唇花
TCMBANKHE005432/YNS-47/YEM-51/XU-527 Salvia przewalskii|Salvia przewalskii Maxim.var.mandarinorum(Diels) Stib.|Salvia przewalskii Maxim. 甘西鼠尾草|褐毛甘西鼠尾|甘西鼠尾 大紫丹参|甘西鼠尾 云南药材标准:第七册|云南民族药物志:第一卷|西藏昌都市芒康县 活血化瘀,通经止痛,清心安神。用于胸痹心痛,心烦失眠,脘腹胁痛,痛经、经闭、产后恶露不尽,风湿痹痛,癥瘕,疮疡肿痛。|See Salvia miltiorrhiza ./See Salvia miltiorrhiza . 彝族/藏族
TCMBANKHE001695/YEM-754 Fructus Galangae|Alpinia galanga(L.)Willd. 红豆蔻|大高良姜 红豆蔻 云南民族药物志:第四卷 Treatment of epigastric pain accompanied by cold sensation, retention of undigested food with abdominal distension, vomiting and diarrhea, excessive alcohol drinking./Treatment of epigastric pain accompanied by cold sensation, retention of undigested food with abdominal distension, vomiting and diarrhea, excessive alcohol drinking. 阿昌族/傣族/德昂族/哈尼族/基诺族/景颇族/傈僳族/藏族
TCMBANKHE005826/YEM-914/XU-670 Alpinia japonica|Alpinia japonica(Thunb.)Miq. 土砂仁|山姜 山姜 云南民族药物志:第五卷|海南省三亚市崖州区 To move qi, regulate center, fortify stomach./Glomus, abdominal distention and pain, vomiting, diarrhea. 傣族/德昂族/景颇族/傈僳族/瑶族/壮族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE000309 SCN5A CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 sodium voltage-gated channel alpha subunit 5
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000476 NCOA2 GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75 nuclear receptor coactivator 2
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000784 CALM3 CALM; CAM1; CAM2; CAMB; CPVT6; CaM; CaMIII; HEL-S-72; LQT16; PHKD; PHKD3 calmodulin 3
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1