Compound Summary
药名: | Gentiacaulein |
别名: | gentiacauleine;NSC661743; BDBM174835; 2,8-Dihydroxy-1,6-dimethoxyxanthone; AIDS142918; NP-008544; 2,8-dihydroxy-1,6-dimethoxy-xanthen-9-one; 1,7-dihydroxy-3,8-dimethoxyxanthone; CHEBI:5313; 2,8-Dihydroxy-1,6-dimethoxy-9H-xanthen-9-one; DTXSID10415161; 2,8-dihydroxy-1,6-dimethoxyxanthen-9-one; CHEMBL467590; 2,8-dihydroxy-1,6-dimethoxy-9-xanthenone; 15402-27-4; 2,8-dihydroxy-1,6-dimethoxy-xanthone; NSC-661743; 2,8-dihydroxy-1,6-dimethoxyxanthone; gentiacaulein; US9114126, 2027BA1; MLS000563494; 2,6-dimethoxyxanthone; HMS3338N03; AIDS-142918; AC1NQYS1; HMS2227I16; SMR000232301; C10064; Getiacaulein |
分子式: | C15H12O6 |
Smiles: | COC1=CC(=C2C(=C1)OC3=C(C2=O)C(=C(C=C3)O)OC)O |
成分: | HBIN027488 |
OB_score: | 72.816533 |
CAS_id: | 15402-27-4 |
SymMap_id: | SMIT07314;SMIT19201 |
TCMID_id: | 31017 |
TCMSP_id: | MOL005575 |
PubChem_id: | 5281634 |
植物ID | 拉丁名 | 药用植物名 | 药名 | 来源 | 功能与主治 | 使用民族 |
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TCMBANKHE000999 | 红芪 | to promote the drainage of pus and the growth of new tissue. | ||||
TCMBANKHE002758 | Phlomis pungens | |||||
TCMBANKHE004098 | Herba Swertiae | 青叶胆 | To increase the flow of bile, and to remove heat and damp./Damp-heat jaundice, heat strangury with inhibited pain, damp-heat diarrhea dysentery, red and white vaginal discharge, influenza, malaria with fever, acute gastritis, acute pharyngolaryngitis, acute tonsillitis, acute conjunctivitis, allergic dermatitis. | |||
TCMBANKHE006338 | Glycyrrhiza glabra | 光果甘草 | See Glycyrrhiza uralensis ./See Glycyrrhiza uralensis . | |||
TCMBANKHE004564 | Larrea divaricata | 极叉开拉瑞阿 | ||||
TCMBANKHE005082 | Semen Persicae | 桃仁 | To promote blood circulation, to eliminate phlegm, and to relax the bowels./Amenorrhea, dysmenorrhea, concretion and conglomeration, lump glomus, knocks and falls, intestinal dry and constipation. | |||
TCMBANKHE007818 | Larrea tridentata | 三齿拉瑞阿 | ||||
TCMBANKHE006523/XU-115 | Flos Genkwa|Daphne genkwa Sieb. et Zucc | 芫花 | 湖北神农架 | 1. To transform water and stop cough; 2. To resolve phlegm and stop cough; 3. To kill worms/Edema, ascites, hydrothorax, cough with profuse phlegm, chronic bronchitis, malaria, scalp infection, infection of skin, tinea capitis, neurodermatitis, induce abortion, toothache. | ||
TCMBANKHE005271/YNS-173/XU-59 | Rosmarinus officinalis|Rosmarinus officinalis Linn.|Rosmarinus officinalis L. | 迷迭香 | 迷迭香 | 云南药材标准:第四册|云南省昆明市盘龙区 | 祛风解表,健脾和胃,理气止痛。用于外感头痛,头风痛, 饮食积滞,脘腹胀痛|To effuse sweat, fortify spleen, quiet spirit, relieve pain./Headache, prevention of hair loss in early stage. | |
TCMBANKHE004550/YEM-551 | Artemisia capillaris|Artemisia capillaris Thunb. | 茵陈蒿 | 茵陈 | 云南民族药物志:第三卷 | To clear heat and disinhibit damp, abate jaundice./Hepatitis, jaundice, infective cholecystitis, hyperlipemia, inhibited urination, damp sore, itchy skin. | 阿昌族/傣族/德昂族/景颇族/傈僳族/瑶族/彝族/藏族/壮族 |
TCMBANKHE007013/YEM-944 | Prunus pseudocerasus|Prunus pseudocerasus Lindl. | 樱桃 | 樱桃 | 云南民族药物志:第五卷 | To supplement spleen and boost kidney./Paralysis, spleen vacuity diarrhea, kidney vacuity and emission, pain in lumbus and legs, numbness in limbs. | 彝族 |
疾病ID | 病名 | 疾病类型 | MeSH | 参考文献 |
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靶点ID | 基因名 | 基因别名 | 描述 |
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TCMBANKGE000181 | PIM1 | PIM | Pim-1 proto-oncogene, serine/threonine kinase |
TCMBANKGE000201 | ESR1 | ER; ESR; ESRA; ESTRR; Era; NR3A1 | estrogen receptor 1 |
TCMBANKGE000205 | NOS2 | HEP-NOS; INOS; NOS; NOS2A | nitric oxide synthase 2 |
TCMBANKGE000286 | GSK3B | - | glycogen synthase kinase 3 beta |
TCMBANKGE000309 | SCN5A | CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 | sodium voltage-gated channel alpha subunit 5 |
TCMBANKGE000360 | CCNA2 | CCN1; CCNA | cyclin A2 |
TCMBANKGE000474 | NCOA1 | F-SRC-1; KAT13A; RIP160; SRC1; bHLHe42; bHLHe74 | nuclear receptor coactivator 1 |
TCMBANKGE000476 | NCOA2 | GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75 | nuclear receptor coactivator 2 |
TCMBANKGE000478 | CHEK1 | CHK1 | checkpoint kinase 1 |
TCMBANKGE000701 | ESR2 | ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 | estrogen receptor 2 |
TCMBANKGE000813 | DPP4 | ADABP; ADCP2; CD26; DPPIV; TP103 | dipeptidyl peptidase 4 |
TCMBANKGE000903 | PTGS1 | COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS | prostaglandin-endoperoxide synthase 1 |
TCMBANKGE000938 | CDK2 | CDKN2; p33(CDK2) | cyclin dependent kinase 2 |
TCMBANKGE001073 | PTGS2 | COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 | prostaglandin-endoperoxide synthase 2 |
TCMBANKGE001185 | PPARG | CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma | peroxisome proliferator activated receptor gamma |
TCMBANKGE001202 | MAPK14 | CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA | mitogen-activated protein kinase 14 |
TCMBANKGE004266 | AR | AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM | androgen receptor |
TCMBANKGE006339 | CA2 | CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 | carbonic anhydrase 2 |
TCMBANKGE008921 | RXRA | NR2B1 | retinoid X receptor alpha |
TCMBANKGE011079 | PRSS1 | TRP1; TRY1; TRY4; TRYP1 | serine protease 1 |
TCMBANKGE014941 | DPEP1 | MBD1; MDP; RDP | dipeptidase 1 |