Compound Summary


  Compound Information

药名:

Gentisin

别名:

C10066; 1,7-dihydroxy-3-methoxy-xanthen-9-one; 1,7-Dihydroxy-3-methoxyxanthen-9-one; 1,7-Dihydroxy-3-methoxyxanthone; gentisin; Gentisine; AIDS351438; AIDS-351438; 1,7-dihydroxy-3-methoxy-9-xanthenone; BRN 0384788; 437-50-3; Xanthen-9-one, 1,7-dihydroxy-3-methoxy-; CCRIS 3151; Gentianin; 9H-Xanthen-9-one, 1,7-dihydroxy-3-methoxy-; 1,7-dihydroxy-3-methoxy-xanthone; EINECS 207-114-1; GENTIANIC ACID; 5-18-04-00497 (Beilstein Handbook Reference);

分子式:

C14H10O5

Smiles:

COC1=CC(=C2C(=C1)OC3=C(C2=O)C=C(C=C3)O)O

成分:

HBIN027522;HBIN002017

OB_score:

64.061927

CAS_id:

437-50-3

SymMap_id:

SMIT05281

TCMID_id:

31021;6010

TCMSP_id:

MOL003152

PubChem_id:

5281636


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000935 Garcinia eugenifolia
TCMBANKHE002511 Citrus cultivars 栽培柑橘 See Citrus chachiensis ./See Citrus chachiensis.
TCMBANKHE003730 Gentiana scabra var. buesgeri 龙胆 Acute icterohepatitis, urinary tract infection, acute conjunctivitis, dribbling pain of urination, damp-heat jaundice, genital swelling and itch, damp-heat vaginal discharge, distended head and headache due to liver-gallbladder repletion fire, red eyes with gall, deafness, swelling in ear, pain in rib-side, bitter taste, fright wind and convulsion.
TCMBANKHE003804 Swertia pseudochinensis 獐牙菜 To drain fire and resolve toxin, disinhibit damp, fortify spleen./Acute icterohepatitis, chronic liver diseases, damp-heat jaundice, dysentery, gastritis, indigestion, acute conjunctivitis, toothache, mouth sore, swelling pain of sores.
TCMBANKHE004097 Citrus limonia 黎檬叶 See Citrus limon./See Citrus limon.
TCMBANKHE004259 Plantago major 大车前 See Plantago asiatica./See Plantago asiatica.
TCMBANKHE005015 Pterocarpus santalinus 似紫檀
TCMBANKHE007112 Gentiana lutea 黄龙胆
TCMBANKHE006985 Citrus limonia 黎檬根 See Citrus limon./See Citrus limon.
TCMBANKHE006535 Eucalyptus grandis 巨桉
TCMBANKHE008334 Calophyllum brasiliense
TCMBANKHE005644/XU-300 Helianthus tuberosus 菊芋 陕西省安康市旬阳市 To clear heat and cool blood, disperse swelling./Febrile diseases, intestinal heat bleeding, knocks and falls, swelling pain from fracture.
TCMBANKHE003831/YEM-100 Polygala tenuifolia|Polygala sibirica L. 远志|西伯利亚远志 苦远志 云南民族药物志:第一卷 To quiet heart and spirit, dispel phlegm and open orifices, resolve toxin and disperse swelling./Pharyngitis, disquieted heart spirit, fright palpitation and insomnia, amnesia, fright epilepsy, cough with profuse phlegm, effusion of back from welling abscess and flat abscess, painful swollen breast. 白族/拉祜族/傈僳族/纳西族/佤族/瑶族/壮族
TCMBANKHE008889/YEM-330 Mesua ferrea|Mesua ferrea L. 铁力木 铁力木 云南民族药物志:第二卷 To relieve cough and dispel phlegm, resolve toxin and disperse swelling./Cough with profuse phlegm, swelling of sore welling abscess and boil, bleeding from hemorrhoids, scalds, poisonous snake bite. 傣族
TCMBANKHE004332/YEM-378/XU-663 Foeniculum vulgare|Foeniculum vulgare Mill. 茴香茎叶|茴香 小茴香 云南民族药物志:第二卷|云南省玉溪市澄江县 To expel wind, normalize qi, relieve pain./Sand qi, mounting qi, swollen welling abscess. 白族/布依族/傣族/傈僳族/纳西族/彝族/藏族/壮族
TCMBANKHE008084/YEM-516 Raphanus sativus|Raphanus sativus L. 莱菔|萝卜 萝卜 云南民族药物志:第三卷 To disperse food, precipitate qi, transform phlegm, stanch bleeding, allay thirst, disinhibit urine./Indigestion, food accumulation distention and fullness, hyperchlorhydria, vomiting, diarrhea, dysentery, constipation, phlegm-heat cough, hemoptysis, blood ejection, spontaneous external bleeding, hematochezia, diabetes mellitus, strangury-turbidity, sores, stasis swelling due to injury, scalds, frostbite. 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/水族/佤族/彝族/藏族
TCMBANKHE006587/YEM-983 Radix Dipsaci|Dipsacus asperoides C.Y.Cheng et T.M.Ai 续断|川续断 续断 云南民族药物志:第五卷 For tonifying yang/See Dipsacus asperoides. 白族/布依族/傣族/德昂族/哈尼族/景颇族/拉祜族/傈僳族/苗族/纳西族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE000994 AKR1B1 ADR; ALDR1; ALR2; AR aldo-keto reductase family 1 member B
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE007924 PKIA PRKACN1 cAMP-dependent protein kinase inhibitor alpha
TCMBANKGE014941 DPEP1 MBD1; MDP; RDP dipeptidase 1