Compound Summary

  Compound Information

TCMBANKIN061781

药名:	hernandin
别名:	69222-20-4 (UNSPECIFIED); AIDS006791; Deoxypodophyllotoxin; AIDS-006791; (5aR,8aR,9R)-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofurano[5,6-f][1,3]benzodioxol-8-one; (-)-Deoxypodophyllotoxin; (-)-Anthricin; Hernandin; Anthricin; DPT; Podophyllotoxin, deoxy-; SILICICOLIN; Desoxypodophyllotoxin; Anthriscin; NCI60_003794; (-)-Desoxypodophyllotoxin; 19186-35-7; 19186-35-7 (5R,5AR,8AR); Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-5-(3,4,5-trimethoxyphenyl)-,(5R,5aR,8aR)-; 5,8,8a,9,-Tetrahydro-5-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one; NSC403148; Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-5-(3,4,5-trimethoxyphenyl)-, (5R,5aR,8aR)-; C10556; 4-Deoxypodophyllotoxin; deoxypodophyllotoxin; (-)-deoxypodophyllotoxin; anthricin isomer; isoanthricin; anthricin
分子式:	C22H22O7
Smiles:	COC1=CC(=CC(=C1OC)OC)C2C3C(CC4=CC5=C(C=C24)OCO5)COC3=O
成分:	HBIN029171;HBIN023390;HBIN023391;HBIN016300;HBIN030432;HBIN016299
OB_score:	37.749395
CAS_id:	19186-35-7
SymMap_id:	SMIT04071
TCMID_id:	9442;23247;1373;11225;1372
TCMSP_id:	MOL001700
PubChem_id:	345501;71045228;2203

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE000174		八角莲
TCMBANKHE002438	Juniperus sabina var. tamariscifolia
TCMBANKHE003761	Hernandia sonora [Syn. Hernandia ovigera ]	莲叶桐			To drain precipitation and free stool, anticancer./Constipation, malignant tumor (therioma), nervous system diseases, cardiovascular diseases.
TCMBANKHE003903	Bursera microphylla	小叶裂榄
TCMBANKHE004282	Anthriscus sylvestris	峨参			To supplement spleen and boost qi, disperse swelling./Spleen vacuity and food distention, stomachache, lassitude in limbs, cough and asthma due to lung vacuity, senile nocturia, blood ejection from knocks and falls.
TCMBANKHE008195	Thuja occidentalis	北美崖柏
TCMBANKHE006698	Juniperus silicicola	南美洲桧
TCMBANKHE005696/XU-552	Peganum harmala	骆驼蓬		甘肃省定西市岷县	To diffuse lung qi, dispel wind-damp, disperse swelling toxin./Cough and shortness of breath, wind-damp impediment pain, itchy skin, innominate toxin swelling.
TCMBANKHE008280	Thujopsis dolobrata	罗汉柏
TCMBANKHE008587	Juniperus sabina	叉子圆柏
TCMBANKHE006431/XU-713	Mallotus anomalus	锈毛野桐		海南省三亚市崖州区
TCMBANKHE008194	Podophyllum emodii	桃儿七			To dispel wind and eliminate damp, quicken blood and relieve pain, relieve cough and dispel phlegm./Wind-damp impediment pain, knocks and falls, menstrual disorder, dysmenorrhea, pain in stomach duct and abdomen, cough.
TCMBANKHE009095/YNS-1	Dysosma versipellis [Syn. Podophyllum versipelle ]|Dysosma versipellis (Hance) M. cheng ex Ying	鬼臼|八角莲	八角莲	云南药材标准：第一册	清热解毒，化痰散结，祛瘀消肿。用于咳嗽，咽喉肿痛，痈肿痔疮，瘰疬，跌打损伤，毒蛇咬伤。|See Dysosma pleiantha./See Dysosma pleiantha .
TCMBANKHE008322/YNS-1/YEM-371	Dysosma pleiantha [Syn. Podophyllum pleianthum]|Dysosma versipellis (Hance) M. cheng ex Ying|Dysosma veitchii(Hemsl.et Wils.)Fu ex Ying	六角莲|八角莲|川八角莲	八角莲	云南药材标准：第一册|云南民族药物志：第二卷	清热解毒，化痰散结，祛瘀消肿。用于咳嗽，咽喉肿痛，痈肿痔疮，瘰疬，跌打损伤，毒蛇咬伤。|To transform phlegm and dissipate binds, dispel stasis and relieve pain, clear heat and resolve toxin./Cough, swelling pain in throat, scrofula, goiter and tuberculosis, swollen welling abscess, clove sore, poisonous snake bite, knocks and falls, pain in joints.	水族/彝族/壮族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000017	MAPT	DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU	microtubule associated protein tau
TCMBANKGE000121	KCNH2	ERG-1; ERG1; H-ERG; HERG; HERG1; Kv11.1; LQT2; SQT1	potassium voltage-gated channel subfamily H member 2
TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000286	GSK3B	-	glycogen synthase kinase 3 beta
TCMBANKGE000474	NCOA1	F-SRC-1; KAT13A; RIP160; SRC1; bHLHe42; bHLHe74	nuclear receptor coactivator 1
TCMBANKGE000476	NCOA2	GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75	nuclear receptor coactivator 2
TCMBANKGE000478	CHEK1	CHK1	checkpoint kinase 1
TCMBANKGE000701	ESR2	ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8	estrogen receptor 2
TCMBANKGE000784	CALM3	CALM; CAM1; CAM2; CAMB; CPVT6; CaM; CaMIII; HEL-S-72; LQT16; PHKD; PHKD3	calmodulin 3
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000857	AHSA1	AHA1; C14orf3; hAha1; p38	activator of HSP90 ATPase activity 1
TCMBANKGE000903	PTGS1	COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS	prostaglandin-endoperoxide synthase 1
TCMBANKGE000979	KDR	CD309; FLK1; VEGFR; VEGFR2	kinase insert domain receptor
TCMBANKGE001037	MMP2	CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1	matrix metallopeptidase 2
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001118	MMP9	CLG4B; GELB; MANDP2; MMP-9	matrix metallopeptidase 9
TCMBANKGE001184	RELA	CMCU; NFKB3; p65	RELA proto-oncogene, NF-kB subunit
TCMBANKGE001185	PPARG	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma	peroxisome proliferator activated receptor gamma
TCMBANKGE001201	MAPK3	ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; p44-ERK1; p44-MAPK	mitogen-activated protein kinase 3
TCMBANKGE001203	MAPK1	ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK	mitogen-activated protein kinase 1
TCMBANKGE001862	TUBB4B	Beta2; LCAEOD; TUBB2; TUBB2C	tubulin beta 4B class IVb
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE006339	CA2	CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282	carbonic anhydrase 2
TCMBANKGE008723	PDE10A	ADSD2; HSPDE10A; IOLOD; LINC00473; PDE10A19	phosphodiesterase 10A
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1