Compound Summary

  Compound Information

TCMBANKIN061806

药名:	aristolochicacid iva
别名:	aristolochic acid Ⅳa; aristolochic acid D;Aristoloside_qt
分子式:	C17H11NO8
Smiles:	COC1=CC(=CC2=C3C(=C(C=C12)[N+](=O)[O-])C(=CC4=C3OCO4)C(=O)O)O
成分:	HBIN016809;HBIN016830
OB_score:	40.318095
CAS_id:	17413-38-6
SymMap_id:	SMIT03293
TCMID_id:	1719
TCMSP_id:	MOL000763
PubChem_id:	161218

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE004385	Fructus Aristolochiae	马兜铃			To remove heat from the lung and relieve cough and asthma, and to remove heat from the large intestine./Lung heat cough asthma, phlegm congestion and hasty qi , lung vacuity enduring cough, intestinal heat bleeding from hemorrhoids, swelling pain from hemorrhoids, edema.
TCMBANKHE003156		寻骨风			Treatment of wind-damp obstruction syndrome manifested as joint pain, numbness of the limbs, tendon and muscle spasms and pain from external injury. Hairy birthwort (Xungufeng) may be used alone in decoction or soaked in wine, or used with other herbs tha
TCMBANKHE004913	Aristolochia mollissima	绵毛马兜铃			To dispel wind and eliminate damp, quicken blood and free network vessels, relieve pain./Wind-damp impediment pain, numbness in limbs, hypertonicity of sinews and bones, pain in stomach duct and abdomen, painful wound from knocks and falls, bleeding due to external injury, mammary welling abscess, suppurative infection.
TCMBANKHE008697	Caulis Aristolochiae seu Clematis	木通			1. To promote water metabolism and relieve abnormal urination; 2. To clear heat and promote lactation/Acute urethritis, short voidings of reddish urine, strangury-turbidity, edema, nephritis with edema, galactostasis, heat vexation in chest, throat pain, mouth sore, tongue sores, wind-damp impediment pain, galactostasis, amenorrhea, dysmenorrhea.
TCMBANKHE006083/YEM-791	Herba Aristolochiae;Fibraurea recisa Pierre|Fibraurea recisa Pierre	天仙藤	大黄藤	云南民族药物志：第四卷	To promote the flow of qi and blood, and to induce diuresis./Acute tonsillitis, pharyngolaryngitis, infection of upper respiratory tract, conjunctivitis, jaundice, gastroenteritis, dysentery, child indigestion, food poisoning, salpingitis, acute endometritis, chronic endometritis, acute pelvic inflammation, vaginitis, sore and boil, burns and scalds.	瑶族/壮族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000168	NR3C1	GCCR; GCR; GCRST; GR; GRL	nuclear receptor subfamily 3 group C member 1
TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000286	GSK3B	-	glycogen synthase kinase 3 beta
TCMBANKGE000360	CCNA2	CCN1; CCNA	cyclin A2
TCMBANKGE000476	NCOA2	GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75	nuclear receptor coactivator 2
TCMBANKGE000701	ESR2	ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8	estrogen receptor 2
TCMBANKGE000737	PGR	NR3C3; PR	progesterone receptor
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000903	PTGS1	COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS	prostaglandin-endoperoxide synthase 1
TCMBANKGE000938	CDK2	CDKN2; p33(CDK2)	cyclin dependent kinase 2
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001185	PPARG	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma	peroxisome proliferator activated receptor gamma
TCMBANKGE001202	MAPK14	CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA	mitogen-activated protein kinase 14
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1