Compound Summary


  Compound Information

药名:

Calycosin-7-0-β-D-glucopyranoside

别名:

4H-1-Benzopyran-4-one, 7-(beta-D-glucopyranosyloxy)-3-(4-methoxyphenyl)-; MEGxp0_000395; 3-(4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one; LMPK12050014; 486-62-4; 3-(4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-chromen-4-one; 3-(4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-chromone; Formononetin glucoside; STOCK1N-14986; 75375_FLUKA; 3-(4-methoxyphenyl)-4-oxo-4H-chromen-7-yl beta-D-glucopyranoside; ACon1_000463; ZINC01081322; 3-(4-methoxyphenyl)-7-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-tetrahydropyranyl]oxy]-4-chromenone; CHEBI:7775; 3-(4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-chromen-4-one; Ononin; C10509; Formononetin 7-O-glucoside; Formononetin-7-O-beta-D-glucopyranoside; Formononetin-7-glucoside; ononin

分子式:

C22H22O9

Smiles:

COC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)OC4C(C(C(C(O4)CO)O)O)O

成分:

HBIN019426;HBIN038168

CAS_id:

486-62-4

SymMap_id:

SMIT01988;SMIT03002

TCMID_id:

37009;24040

TCMSP_id:

MOL000391

PubChem_id:

44257215


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000312 Radix Glycyrrhizae Preparata 炙甘草 Treatment of deficiency of spleen and stomach, lassitude, palpitation, arrhythmia./Treatment of deficiency of spleen and stomach, lassitude, palpitation, arrhythmia.
TCMBANKHE000702 Radix Glycyrrhizae Praeparata 炙草 Treatment of deficiency of spleen and stomach, lassitude, palpitation, arrhythmia./Treatment of deficiency of spleen and stomach, lassitude, palpitation, arrhythmia.
TCMBANKHE000956 flos puerariae lobatae 葛花 To relieve fever, to promote the production of body fluid,to facilitate eruption, and to arrest diarrhea./Treatment of fever, headache and stiffness of th nape in exogenous affections, thirst, diabetes, measles with inadequate eruption, acute dysentery or diarrhea, stiff and painful nape in hypertension.
TCMBANKHE000999 红芪 to promote the drainage of pus and the growth of new tissue.
TCMBANKHE001300 制军炭
TCMBANKHE004897 Piptanthus nanus 小沙冬青 See Ammopiptanthus mongolicus./See Ammopiptanthus mongolicus.
TCMBANKHE003728 Radix Glycyrrhizae 甘草 To reinforce the function of the spleen and replenish qi, to remove heat and counteract toxicity, to dispel phlegm and relieve cough, to alleviate spasmodic pain, and to moderate drug actions./1. Its decoction can inhibit intestinal smooth muscles of rabbins in vitro, but glycyrrhizin and glycyrrhetinic acid have no this effect.2. Possessing an adrenocorticomimetic effect.3. Its extract and glycyrrhizin exerts a detoxifying effect.4. Antitussive and antiasthmatic. 5. Glycyrrhizin has anti-inflammatory effect similar to hydrocortisone.
TCMBANKHE003743 Radix Astragali 黄芪 To reinoforce qi and invigorate the function of the spleen./Common cold, influenza, chronic wound ulcer, chronic glomerulonephritis, diabetes mellitus due to internal heat, qi vacuity edema, chronic gastritis, qi vacuity and hypodynamia, reduced food intake and sloppy stool, center qi fall, chronic diarrhea, prolapse of rectum, hematochezia, flooding and spotting, spontaneous sweating due to exterior vacuity.
TCMBANKHE003749 Radix Puerariae 葛根 To relieve fever, to promote the production of body fluid,to facilitate eruption, and to arrest diarrhea./Angina pectoris, hypertension, headache due to externally contracted wind-heat, rigidity of neck, thirst, diabetes mellitus, non-eruption of measles, heat dysentery, diarrhea, deafness in early stage, optic nerve atrophy, retinitis.
TCMBANKHE003898 Lycopodium cernuum 铺地蜈蚣 See Lycopodium japonicum./See Lycopodium japonicum.
TCMBANKHE006212 Semen Astragali Complanati;Semen Astragali Complati 潼蒺藜;沙苑子 Treatment of back pain, nocturnal emission and premature ejaculation in deficiency syndromes of the kidney, turbid discharge with urination, excessive leukorrhea, dribbling of urine after urination, dizziness and blurred vision,to benefit the liver./Treatment of back pain, nocturnal emission and premature ejaculation in deficiency syndromes of the kidney, turbid discharge with urination, excessive leukorrhea, dribbling of urine after urination, dizziness and blurred vision.
TCMBANKHE006366 Radix Moghaniae Philippinensis 千斤拔
TCMBANKHE008626 Cortex Lycii Radicis 地骨皮 To reduce heat in blood, to relieve consumptive fever, and to remove heat from the lung./1. Its decoction, infusion, tincture and injection exert a hypotensive effect on anesthetized or unanesthetized animals.2. Antipyretic. Reducing vaccine-induced fever in rabbits.3. Its extract lowers serum cholesterol level in rabbits,4. Its decoction reduces blood sugar level in rabbits5. An active component, betaine, possesses a lipocaic effect.
TCMBANKHE007721 Exocarpium Benincasae 冬瓜皮 1. To promote diuresis to relieve edema. 2. To clear summer-heat./Edema, inhibited urination [=dysuria], diarrhea, swelling of sores.
TCMBANKHE005773 Herba Lycopodii 伸筋草 To relieve rheumatic conditions and muscular contracture./Wind-cold-damp impediment, aching pain in joints, arthritis, dysmenorrhea, skin numbness, weakness in limbs, jaundice, cough, knocks and falls, sores, zoster, scalds.
TCMBANKHE006428 Herba Cistanches 肉苁蓉 To reinforce the kidney, replenish vital essence and blood, and induce Taxation./Impotence, infertility, backache, limp aching lumbus and knees, weakness in sinews and bones, intestinal dry and constipation.
TCMBANKHE008538 土荆皮 Scab and lichen, eczema, neurodermatitis .
TCMBANKHE007847 Caulis Millettiae; Caulis spatholobi 鸡血藤 To enrich the blood, to activate blood circulation, and to remove obstruction of the channels and collaterals./Treatment of menstrual disorders, anemia, numbness and paralysis, rheumatic arthralgia.
TCMBANKHE008315 Cortex erythrie 海桐皮 1. To dispel wind and dampness; 2. To clear the meridians/Wind-damp impediment, pain in lumbus and knees, scab sore, lichen, eczema.
TCMBANKHE005824/XU-618 Herba Alternantherae|Alternanthera philoxeroides 空心莲子草|喜旱莲子草(空心莲子草) 云南省昭通市盐津县 To clear heat and toxic materials, promote diuresis. For heat-syndrome, intense heat-syndrome and dampness-heat syndrome. Recently, for preventing and treating encephalitis B, epidemic ho\emorrhagic fever, viral hepatitis, eyedrops for epidemic conjunctivitis and viral keratitis, local application for herpes zoster. Also for furuncle, snake bite, stranguria with turbid urine, etc./To clear heat and toxic materials, promote diuresis. For heat-syndrome, intense heat-syndrome and dampness-heat syndrome. Recently, for preventing and treating encephalitis B, epidemic ho\emorrhagic fever, viral hepatitis, eyedrops for epidemic conjunctiv
TCMBANKHE005199/YEM-416/XU-321 Fructus Xanthii sibirici|Xanthium sibiricum Patrin ex Widder|Xanthium sibiricum 苍耳子|苍耳 苍耳子 云南民族药物志:第二卷|贵州省毕节市赫章县 To dispel wind and damp, and to relieve nasal obstruction./1. Lowering blood sugar, with similar mechanism as phenethyl biguanide ( DBI ). 2. Its chief poisonous component is rhamnose. The toxic effects in rats, guinea-pigs and rabbits by different routes of administration are similar. LD50 is 0.93g/kg in mice. 阿昌族/白族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/彝族/藏族
TCMBANKHE003926/YEM-709 Herba Lycopodii;Lycopodium japonium;Common Clubmoss Herb|Lycopodium japonicum Thunb.ex hwvzay 伸筋草|石松 石松 云南民族药物志:第四卷 To relieve rheumatic conditions and muscular contracture.;Treatment of arthralgia with limited mobility of the joints./Wind-cold-damp impediment, aching pain in joints, arthritis, dysmenorrhea, skin numbness, weakness in limbs, jaundice, cough, knocks and falls, sores, zoster, scalds.;Treatment of arthralgia with limited mobility of the joints. 布依族/傣族/基诺族/傈僳族/苗族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000979 KDR CD309; FLK1; VEGFR; VEGFR2 kinase insert domain receptor
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE003643 F7 SPCA coagulation factor VII
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2