Compound Summary


  Compound Information

药名:

Aristololactum

别名:

13395-02-3; NSC 87406; 4-27-00-06628 (Beilstein Handbook Reference); BRN 0307971; Benzo(f)-1,3-benzodioxolo(6,5,4-cd)indol-5(6H)-one, 8-methoxy-; NSC87406; Aristolactam I; ARISTOLOLACTAM; CCRIS 1545; aristolactam i; Aristolactam

分子式:

C17H11NO4

Smiles:

COC1=CC=CC2=C3C4=C(C=C21)NC(=O)C4=CC5=C3OCO5

成分:

HBIN016822; HBIN016774; HBIN016758

OB_score:

24.148491

CAS_id:

13395-02-3

SymMap_id:

SMIT04604

TCMID_id:

1698; 36697

TCMSP_id:

MOL002345

PubChem_id:

96710


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE003156 寻骨风 Treatment of wind-damp obstruction syndrome manifested as joint pain, numbness of the limbs, tendon and muscle spasms and pain from external injury. Hairy birthwort (Xungufeng) may be used alone in decoction or soaked in wine, or used with other herbs tha
TCMBANKHE004385 Fructus Aristolochiae 马兜铃 To remove heat from the lung and relieve cough and asthma, and to remove heat from the large intestine./Lung heat cough asthma, phlegm congestion and hasty qi , lung vacuity enduring cough, intestinal heat bleeding from hemorrhoids, swelling pain from hemorrhoids, edema.
TCMBANKHE004840 Nerium indicum 夹竹桃 To strengthen heart and disinhibit urine, dispel phlegm and settle asthma, settle pain, dispel stasis./Congestive cardiac failure, cough and asthma, epilepsy, painful swelling from knocks and falls, amenorrhea due to blood stasis.
TCMBANKHE004913 Aristolochia mollissima 绵毛马兜铃 To dispel wind and eliminate damp, quicken blood and free network vessels, relieve pain./Wind-damp impediment pain, numbness in limbs, hypertonicity of sinews and bones, pain in stomach duct and abdomen, painful wound from knocks and falls, bleeding due to external injury, mammary welling abscess, suppurative infection.
TCMBANKHE006788 Aristolochia fangchi 广防己 To dispel wind and relieve pain, clear heat and disinhibit water./Damp-heat generalized pain, wind-damp impediment pain, edema in lower limb, inhibited urination.
TCMBANKHE007238 Radix Stephaniae Tetrandrae 防己 To cause diuresis and to relieve rheumatic conditions./Beriberi with edema, inhibited urination, eczema, sore toxin, wind-damp impediment pain, hypertension, adjuvant in anesthesia.
TCMBANKHE004227/XU-506 Aristolochia manshuriensis 关木通|木通马兜铃 云南省红河州金平县 To clear heart fire, disinhibit urine, free menstruation and milk./Mouth sore, tongue sores, vexation and reddish urine, edema, heat strangury with inhibited pain, leukorrhea, amenorrhea and scant milk, damp-heat impediment pain.
TCMBANKHE003989/YEM-614 Stephania hernandifolia|Stephania hernandifolia (Willd.) Walp. 汝南|桐叶千金藤 南千斤藤 云南民族药物志:第三卷 To clear heat and resolve toxin, dispel wind-damp, relieve pain./Sore toxin of welling abscess and boil, swelling pain in throat, epidemic parotitis, wind-damp impediment pain, dysentery, headache, stomachache, taxation damage and pain. 傣族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE000309 SCN5A CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1 sodium voltage-gated channel alpha subunit 5
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE009294 HTR3A 5-HT-3; 5-HT3A; 5-HT3R; 5HT3R; HTR3 5-hydroxytryptamine receptor 3A
TCMBANKGE014050 GABRA1 ECA4; EIEE19; EJM; EJM5 gamma-aminobutyric acid type A receptor subunit alpha1