Compound Summary


  Compound Information

药名:

Ptelein

别名:

6-methoxy dictamnine;BRN 0616297; 6-Methoxydictamnine; 4,6-dimethoxyfuro[2,3-b]quinoline; 6-Methoxy dictamine; CCRIS 3580; Furo(2,3-b)quinoline, 4,6-dimethoxy-; Pteleine; 2221-41-2

分子式:

C13H11NO3

Smiles:

COC1=CC2=C(C=C1)N=C3C(=C2OC)C=CO3

成分:

HBIN041152;HBIN012519

OB_score:

72.443596

CAS_id:

2221-41-2

SymMap_id:

SMIT07888;SMIT16495

TCMID_id:

13897

TCMSP_id:

MOL006239

PubChem_id:

159650


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE005444 白鲜皮 To clear heat and dry damp, dispel wind and relieve itch, resolve toxin./1. Inhibiting the growth of pathogenic fungi. 2. Its infusion lowers vaccine-induced fever in rabbits. 3. Dictamnine, one of its active components, increase the myocardial tone of frogs. Dermatitis, psoriasis, icterohepatitis, damp-heat sore and papules, profuse pus, yellow-water sore, damp ulceration on skin, itchy skin, damp-heat jaundice, damp-heat impediment.
TCMBANKHE004238/YEM-1014 Phellodendron amurense;Cortex Phellodendri|Phellodendron chinense Schneid var.glabriusculum Schneid. 黄柏|秃叶黄蘗 广西黄柏 云南民族药物志:第五卷 1. To clear heat and dry dampness; 2. To reduce fire and release toxins/Damp-heat dysentery, tuberculosis, epidemic meningitis, acute conjunctivitis, trachoma, fever, abdominal pain, diarrhea, suppurative hematochezia, tenesmus, jaundice, yellow thick foul leukorrhagia, swelling pain in knees and feet, urinary tract infection, boil, sore, ulcer, eczema, mouth sore, hemorrhoids, burns, scalds, exuberance of fire with tidal fever, tidal fever with night sweat, emission. 瑶族/壮族
TCMBANKHE005875/YNS-333/YEM-207/XU-39/XU-129 Mirabilis jalapa|Mirabilis jalapa Linn.|Mirabilis jalapa L. 紫茉莉根|紫茉莉 紫茉莉根|紫茉莉 云南药材标准:第四册|云南民族药物志:第一卷|云南省昆明市盘龙区黑龙潭 淸热利湿,活血消肿。用于乳痈,赤白带下,月经不调;热淋;痈疮肿毒|To clear heat and disinhibit damp, quicken blood and resolve toxin./Heat strangury, white turbidity, edema, red and white vaginal discharge, swelling pain in joints, swelling toxin of welling abscess and sore, mammary welling abscess, knocks and falls. 阿昌族/白族/傣族/德昂族/哈尼族/基诺族/景颇族/傈僳族/佤族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000181 PIM1 PIM Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000360 CCNA2 CCN1; CCNA cyclin A2
TCMBANKGE000478 CHEK1 CHK1 checkpoint kinase 1
TCMBANKGE000938 CDK2 CDKN2; p33(CDK2) cyclin dependent kinase 2
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001467 LTA4H - leukotriene A4 hydrolase
TCMBANKGE001755 MAOB - monoamine oxidase B
TCMBANKGE008921 RXRA NR2B1 retinoid X receptor alpha