Compound Summary
Compound Information
药名: | sulforathane |
别名: | sulforaphane |
分子式: | C6H11NOS2 |
Smiles: | CS(=O)CCCCN=C=S |
成分: | HBIN045135; HBIN045133 |
TCMID_id: | 20462 |
PubChem_id: | 5350 |
植物对应的疾病
| 疾病ID | 病名 | 疾病类型 | MeSH | 参考文献 |
|---|
化合物对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE000009 | GJA1 | AVSD3; CMDR; CX43; EKVP; EKVP3; GJAL; HLHS1; HSS; ODDD; PPKCA | gap junction protein alpha 1 |
| TCMBANKGE000047 | AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | AKT serine/threonine kinase 1 |
| TCMBANKGE000052 | TNF | DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F | tumor necrosis factor |
| TCMBANKGE000126 | NFE2L1 | LCR-F1; NRF1; TCF11 | nuclear factor, erythroid 2 like 1 |
| TCMBANKGE000162 | MMP13 | CLG3; MANDP1; MDST; MMP-13 | matrix metallopeptidase 13 |
| TCMBANKGE000171 | DNMT1 | ADCADN; AIM; CXXC9; DNMT; HSN1E; MCMT; m.HsaI | DNA methyltransferase 1 |
| TCMBANKGE000223 | KEAP1 | INrf2; KLHL19 | kelch like ECH associated protein 1 |
| TCMBANKGE000243 | LMNA | CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; LMNL1; MADA; PRO1 | lamin A/C |
| TCMBANKGE000248 | MMP10 | SL-2; STMY2 | matrix metallopeptidase 10 |
| TCMBANKGE000290 | NQO1 | DHQU; DIA4; DTD; NMOR1; NMORI; QR1 | NAD(P)H quinone dehydrogenase 1 |
| TCMBANKGE000294 | CDKN1A | CAP20; CDKN1; CIP1; MDA-6; P21; SDI1; WAF1; p21CIP1 | cyclin dependent kinase inhibitor 1A |
| TCMBANKGE000297 | JAK2 | JTK10; THCYT3 | Janus kinase 2 |
| TCMBANKGE000298 | SOD1 | ALS; ALS1; HEL-S-44; IPOA; SOD; STAHP; hSod1; homodimer | superoxide dismutase 1 |
| TCMBANKGE000330 | HMOX1 | HMOX1D; HO-1; HSP32; bK286B10 | heme oxygenase 1 |
| TCMBANKGE000389 | MMP3 | CHDS6; MMP-3; SL-1; STMY; STMY1; STR1 | matrix metallopeptidase 3 |
| TCMBANKGE000477 | EZH2 | ENX-1; ENX1; EZH2b; KMT6; KMT6A; WVS; WVS2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| TCMBANKGE000652 | STAT5B | STAT5 | signal transducer and activator of transcription 5B |
| TCMBANKGE000660 | DNMT3B | ICF; ICF1; M.HsaIIIB | DNA methyltransferase 3 beta |
| TCMBANKGE000716 | MT2A | MT-2; MT-II; MT2 | metallothionein 2A |
| TCMBANKGE000728 | MGMT | - | O-6-methylguanine-DNA methyltransferase |
| TCMBANKGE000734 | GCLC | GCL; GCS; GLCL; GLCLC | glutamate-cysteine ligase catalytic subunit |
| TCMBANKGE000793 | ALDH1A1 | ALDC; ALDH-E1; ALDH1; ALDH11; HEL-9; HEL-S-53e; HEL12; PUMB1; RALDH1 | aldehyde dehydrogenase 1 family member A1 |
| TCMBANKGE000812 | REL | C-Rel | REL proto-oncogene, NF-kB subunit |
| TCMBANKGE000838 | PTGES | MGST-IV; MGST1-L1; MGST1L1; MPGES; PGES; PIG12; PP102; PP1294; TP53I12; mPGES-1 | prostaglandin E synthase |
| TCMBANKGE000843 | GSTA4 | GSTA4-4; GTA4 | glutathione S-transferase alpha 4 |
| TCMBANKGE000846 | MMP14 | MMP-14; MMP-X1; MT-MMP; MT-MMP 1; MT1-MMP; MT1MMP; MTMMP1; WNCHRS | matrix metallopeptidase 14 |
| TCMBANKGE000876 | PRDX5 | ACR1; AOEB166; B166; HEL-S-55; PLP; PMP20; PRDX6; PRXV; SBBI10; prx-V | peroxiredoxin 5 |
| TCMBANKGE000886 | SOX9 | CMD1; CMPD1; SRA1; SRXX2; SRXY10 | SRY-box transcription factor 9 |
| TCMBANKGE000920 | GADD45A | DDIT1; GADD45 | growth arrest and DNA damage inducible alpha |
| TCMBANKGE000921 | CCNB1 | CCNB | cyclin B1 |
| TCMBANKGE000941 | TXNRD1 | GRIM-12; TR; TR1; TRXR1; TXNR | thioredoxin reductase 1 |
| TCMBANKGE000955 | ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | ATP binding cassette subfamily C member 2 |
| TCMBANKGE000960 | STAT5A | MGF; STAT5 | signal transducer and activator of transcription 5A |
| TCMBANKGE000969 | TXN | TRDX; TRX; TRX1 | thioredoxin |
| TCMBANKGE000978 | GCLM | GLCLR | glutamate-cysteine ligase modifier subunit |
| TCMBANKGE000992 | KLK3 | APS; KLK2A1; PSA; hK3 | kallikrein related peptidase 3 |
| TCMBANKGE001008 | CYP3A4 | CP33; CP34; CYP3A; CYP3A3; CYPIIIA3; CYPIIIA4; HLP; NF-25; P450C3; P450PCN1 | cytochrome P450 family 3 subfamily A member 4 |
| TCMBANKGE001037 | MMP2 | CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1 | matrix metallopeptidase 2 |
| TCMBANKGE001073 | PTGS2 | COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 | prostaglandin-endoperoxide synthase 2 |
| TCMBANKGE001079 | CYP1A1 | AHH; AHRR; CP11; CYP1; CYPIA1; P1-450; P450-C; P450DX | cytochrome P450 family 1 subfamily A member 1 |
| TCMBANKGE001085 | MAPK8 | JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1c | mitogen-activated protein kinase 8 |
| TCMBANKGE001096 | TLR4 | ARMD10; CD284; TLR-4; TOLL | toll like receptor 4 |
| TCMBANKGE001118 | MMP9 | CLG4B; GELB; MANDP2; MMP-9 | matrix metallopeptidase 9 |
| TCMBANKGE001126 | NFE2L2 | HEBP1; IMDDHH; NRF2; Nrf-2 | nuclear factor, erythroid 2 like 2 |
| TCMBANKGE001132 | BAX | BCL2L4 | BCL2 associated X, apoptosis regulator |
| TCMBANKGE001156 | CASP3 | CPP32; CPP32B; SCA-1 | caspase 3 |
| TCMBANKGE001166 | BCL2 | Bcl-2; PPP1R50 | BCL2 apoptosis regulator |
| TCMBANKGE001169 | BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | BCL2 like 1 |
| TCMBANKGE001172 | HSP90AA1 | EL52; HEL-S-65p; HSP86; HSP89A; HSP90A; HSP90N; HSPC1; HSPCA; HSPCAL1; HSPCAL4; HSPN; Hsp103; Hsp89; Hsp90; LAP-2; LAP2 | heat shock protein 90 alpha family class A member 1 |
| TCMBANKGE001184 | RELA | CMCU; NFKB3; p65 | RELA proto-oncogene, NF-kB subunit |
| TCMBANKGE001201 | MAPK3 | ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; p44-ERK1; p44-MAPK | mitogen-activated protein kinase 3 |
| TCMBANKGE001202 | MAPK14 | CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA | mitogen-activated protein kinase 14 |
| TCMBANKGE001203 | MAPK1 | ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK | mitogen-activated protein kinase 1 |
| TCMBANKGE001456 | PRG4 | CACP; HAPO; JCAP; MSF; SZP | proteoglycan 4 |
| TCMBANKGE001630 | HPX | HX | hemopexin |
| TCMBANKGE001653 | BSPH1 | BSP1; ELSPBP2 | binder of sperm protein homolog 1 |
| TCMBANKGE001681 | ELSPBP1 | E12; EDDM12; EL149; HE12 | epididymal sperm binding protein 1 |
| TCMBANKGE001697 | MMP1 | CLG; CLGN | matrix metallopeptidase 1 |
| TCMBANKGE001774 | SMYD1 | BOP; KMT3D; ZMYND18; ZMYND22 | SET and MYND domain containing 1 |
| TCMBANKGE001818 | NQO2 | DHQV; DIA6; NMOR2; QR2 | N-ribosyldihydronicotinamide:quinone reductase 2 |
| TCMBANKGE002314 | MMP24 | MMP-24; MMP25; MT-MMP 5; MT-MMP5; MT5-MMP; MT5MMP; MTMMP5 | matrix metallopeptidase 24 |
| TCMBANKGE003292 | NFE2L3 | NRF3 | nuclear factor, erythroid 2 like 3 |
| TCMBANKGE003832 | MMP17 | MMP-17; MT4-MMP; MT4MMP; MTMMP4 | matrix metallopeptidase 17 |
| TCMBANKGE003904 | VTN | V75; VN; VNT | vitronectin |
| TCMBANKGE004266 | AR | AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM | androgen receptor |
| TCMBANKGE004355 | EHMT1 | EHMT1-IT1; EUHMTASE1; Eu-HMTase1; FP13812; GLP; GLP1; KLEFS1; KMT1D | euchromatic histone lysine methyltransferase 1 |
| TCMBANKGE004644 | KMT2A | ALL-1; CXXC7; HRX; HTRX1; MLL; MLL1; MLL1A; TRX1; WDSTS | lysine methyltransferase 2A |
| TCMBANKGE005151 | SUV39H1 | H3-K9-HMTase 1; KMT1A; MG44; SUV39H | suppressor of variegation 3-9 homolog 1 |
| TCMBANKGE005267 | SETD1A | EPEDD; KMT2F; Set1; Set1A | SET domain containing 1A, histone lysine methyltransferase |
| TCMBANKGE005330 | ERCC4 | ERCC11; FANCQ; RAD1; XFEPS; XPF | ERCC excision repair 4, endonuclease catalytic subunit |
| TCMBANKGE005592 | SETD7 | KMT7; SET7; SET7/9; SET9 | SET domain containing 7, histone lysine methyltransferase |
| TCMBANKGE005799 | MMP11 | SL-3; ST3; STMY3 | matrix metallopeptidase 11 |
| TCMBANKGE006368 | UGT1A1 | BILIQTL1; GNT1; HUG-BR1; UDPGT; UDPGT 1-1; UGT1; UGT1A | UDP glucuronosyltransferase family 1 member A1 |
| TCMBANKGE006383 | PHF7 | HSPC045; HSPC226; NYD-SP6 | PHD finger protein 7 |
| TCMBANKGE006390 | SUV39H2 | KMT1B | suppressor of variegation 3-9 homolog 2 |
| TCMBANKGE007026 | CBR4 | SDR45C1 | carbonyl reductase 4 |
| TCMBANKGE007074 | NDRG1 | CAP43; CMT4D; DRG-1; DRG1; GC4; HMSNL; NDR1; NMSL; PROXY1; RIT42; RTP; TARG1; TDD5 | N-myc downstream regulated 1 |
| TCMBANKGE007198 | KMT2B | CXXC10; DYT28; HRX2; MLL1B; MLL2; MLL4; TRX2; WBP-7; WBP7 | lysine methyltransferase 2B |
| TCMBANKGE007368 | GSTP1 | DFN7; FAEES3; GST3; GSTP; HEL-S-22; PI | glutathione S-transferase pi 1 |
| TCMBANKGE007551 | SMYD5 | NN8-4AG; RAI15; RRG1; ZMYND23 | SMYD family member 5 |
| TCMBANKGE007602 | MMP7 | MMP-7; MPSL1; PUMP-1 | matrix metallopeptidase 7 |
| TCMBANKGE007692 | GSTM1 | GST1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GTH4; GTM1; H-B; MU; MU-1 | glutathione S-transferase mu 1 |
| TCMBANKGE007823 | MMP23A | MIFR; MIFR-1; MMP21 | matrix metallopeptidase 23A (pseudogene) |
| TCMBANKGE008022 | AKR1C3 | DD3; DDX; HA1753; HAKRB; HAKRe; HSD17B5; PGFS; hluPGFS | aldo-keto reductase family 1 member C3 |
| TCMBANKGE008077 | AKR1C2 | AKR1C-pseudo; BABP; DD; DD-2; DD/BABP; DD2; DDH2; HAKRD; HBAB; MCDR2; SRXY8; TDD | aldo-keto reductase family 1 member C2 |
| TCMBANKGE008186 | SMYD4 | ZMYND21 | SET and MYND domain containing 4 |
| TCMBANKGE008397 | MMP27 | MMP-27 | matrix metallopeptidase 27 |
| TCMBANKGE008600 | TCF20 | AR1; DDVIBA; SPBP; TCF-20 | transcription factor 20 |
| TCMBANKGE008647 | GSTA2 | GST2; GSTA2-2; GTA2; GTH2 | glutathione S-transferase alpha 2 |
| TCMBANKGE008695 | KMT5A | PR-Set7; PR/SET07; SET07; SET8; SETD8 | lysine methyltransferase 5A |
| TCMBANKGE009184 | NSD2 | KMT3F; KMT3G; MMSET; REIIBP; TRX5; WHS; WHSC1 | nuclear receptor binding SET domain protein 2 |
| TCMBANKGE009286 | SETDB1 | ESET; H3-K9-HMTase4; KG1T; KMT1E; TDRD21 | SET domain bifurcated histone lysine methyltransferase 1 |
| TCMBANKGE009358 | MMP15 | MMP-15; MT2-MMP; MT2MMP; MTMMP2; SMCP-2 | matrix metallopeptidase 15 |
| TCMBANKGE009373 | MMP8 | CLG1; HNC; MMP-8; PMNL-CL | matrix metallopeptidase 8 |
| TCMBANKGE009472 | AKR1B10 | AKR1B11; AKR1B12; ALDRLn; ARL-1; ARL1; HIS; HSI | aldo-keto reductase family 1 member B10 |
| TCMBANKGE009688 | MT1A | MT-1A; MT-IA; MT1; MT1S; MTC | metallothionein 1A |
| TCMBANKGE009693 | MMP21 | HTX7; MMP-21 | matrix metallopeptidase 21 |
| TCMBANKGE009726 | ERG | erg-3; p55 | ETS transcription factor ERG |
| TCMBANKGE010139 | MMP26 | - | matrix metallopeptidase 26 |
| TCMBANKGE010293 | SETBP1 | MRD29; SEB | SET binding protein 1 |
| TCMBANKGE010410 | SMYD2 | HSKM-B; KMT3C; ZMYND14 | SET and MYND domain containing 2 |
| TCMBANKGE010442 | SETD2 | HBP231; HIF-1; HIP-1; HSPC069; HYPB; KMT3A; LLS; SET2; p231HBP | SET domain containing 2, histone lysine methyltransferase |
| TCMBANKGE011032 | SETMAR | METNASE; Mar1 | SET domain and mariner transposase fusion gene |
| TCMBANKGE011145 | NSD1 | ARA267; KMT3B; SOTOS; SOTOS1; STO | nuclear receptor binding SET domain protein 1 |
| TCMBANKGE011705 | EZH1 | KMT6B | enhancer of zeste 1 polycomb repressive complex 2 subunit |
| TCMBANKGE011874 | PHF11 | APY; BCAP; IGEL; IGER; IGHER; NY-REN-34; NYREN34 | PHD finger protein 11 |
| TCMBANKGE011882 | EHMT2 | BAT8; C6orf30; G9A; GAT8; KMT1C; NG36 | euchromatic histone lysine methyltransferase 2 |
| TCMBANKGE011927 | CBR3 | HEL-S-25; SDR21C2; hCBR3 | carbonyl reductase 3 |
| TCMBANKGE012035 | SETDB2 | C13orf4; CLLD8; CLLL8; KMT1F | SET domain bifurcated histone lysine methyltransferase 2 |
| TCMBANKGE012200 | NSD3 | KMT3F; KMT3G; WHISTLE; WHSC1L1; pp14328 | nuclear receptor binding SET domain protein 3 |
| TCMBANKGE012277 | MMP25 | MMP-25; MMP20; MMP20A; MMPL1; MT-MMP 6; MT-MMP6; MT6-MMP; MT6MMP; MTMMP6 | matrix metallopeptidase 25 |
| TCMBANKGE012451 | KMT2C | HALR; KLEFS2; MLL3 | lysine methyltransferase 2C |
| TCMBANKGE012477 | MMP20 | AI2A2; MMP-20 | matrix metallopeptidase 20 |
| TCMBANKGE012781 | SETD1B | KMT2G; Set1B | SET domain containing 1B, histone lysine methyltransferase |
| TCMBANKGE013269 | ASH1L | ASH1; ASH1L1; KMT2H; MRD52 | ASH1 like histone lysine methyltransferase |
| TCMBANKGE013320 | HDAC6 | CPBHM; HD6; JM21; PPP1R90 | histone deacetylase 6 |
| TCMBANKGE013409 | GSR | GR; GSRD; HEL-75; HEL-S-122m | glutathione-disulfide reductase |
| TCMBANKGE013636 | GSTA3 | GSTA3-3; GTA3 | glutathione S-transferase alpha 3 |
| TCMBANKGE014249 | GSTA1 | GST-epsilon; GST2; GSTA1-1; GTH1 | glutathione S-transferase alpha 1 |
| TCMBANKGE014269 | AKR1C1 | 2-ALPHA-HSD; 20-ALPHA-HSD; C9; DD1; DD1/DD2; DDH; DDH1; H-37; HAKRC; HBAB; MBAB | aldo-keto reductase family 1 member C1 |
| TCMBANKGE014606 | ERCC5 | COFS3; ERCC5-201; ERCM2; UVDR; XPG; XPGC | ERCC excision repair 5, endonuclease |
| TCMBANKGE014746 | CES1 | ACAT; CE-1; CEH; CES2; HMSE; HMSE1; PCE-1; REH; SES1; TGH; hCE-1 | carboxylesterase 1 |
| TCMBANKGE014817 | KMT2E | HDCMC04P; MLL5; NKp44L; ODLURO | lysine methyltransferase 2E (inactive) |
| TCMBANKGE014891 | MMP19 | CODA; MMP18; RASI-1 | matrix metallopeptidase 19 |
| TCMBANKGE015028 | MMP16 | C8orf57; MMP-X2; MT-MMP2; MT-MMP3; MT3-MMP | matrix metallopeptidase 16 |
| TCMBANKGE015090 | CYP1A2 | CP12; CYPIA2; P3-450; P450(PA) | cytochrome P450 family 1 subfamily A member 2 |
| TCMBANKGE015151 | HPGDS | GSTS; GSTS1; GSTS1-1; PGD2; PGDS | hematopoietic prostaglandin D synthase |
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Dai SX Lab