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疾病ID:TCMBANKDI000031

疾病名:Insulin Resistance

MeSH_Name:Nutritional and Metabolic Diseases

HPO_Name:Abnormality of metabolism/homeostasis

UMLS_Name:Pathologic Function

DO_Name:-

疾病类型:phenotype

DisGeNET_Link:C0021655

MeSH_Link:C18

HPO_Link:HP:0001939

UMLS_Link:T046

DO_Link:-

HERB_ID:-

   疾病对应的植物
ID 拉丁名 药名 药用植物名 功能与主治 来源 药用部位 使用民族
TCMBANKHE000004/YEM-474 Petiolus Trachycarpi|Trachycarpus fortunei (Hook.f.)H.Wendl. 棕榈 棕榈 Treatment of spitting of blood, epistaxis, hematuria, hematochezia, abnormal uterine bleeding./Treatment of spitting of blood, epistaxis, hematuria, hematochezia, abnormal uterine bleeding. 云南民族药物志：第三卷 Trachycarpus fortunei H. Wendl. 阿昌族/白族/傣族/德昂族/哈尼族/景颇族/傈僳族/水族/佤族/彝族
TCMBANKHE003726 Cortex Cinmomi 肉桂 To supplement body fire, reinforce yang, and lead the fire back to the kidney, to dispel cold and relieve pain, and to activate blood circulation and stimulate menstrual discharge./Impotence, uterus cold, cold pain in lumbus and knees, kidney vacuity asthma, yang vacuity dizziness, red eyes and sore pharynx, cold pain in heart and abdomen, vacuity cold vomiting and diarrhea, cold mounting, running piglet, amenorrhea, dysmenorrhea. bark
TCMBANKHE003732 Ganoderma Lucidum seu Japonicum 灵芝(赤芝） Hyperlipemia, coronary heart disease, angina pectoris, septicemia, carcinoma, hepatitis, vacuity taxation, palpitation, insomnia, dizziness, fatigue hypodynamia, enduring cough and asthma, chronic bronchitis, silicosis. dried sporocarp
TCMBANKHE003751/YEM-812 Prunus armeniaca|Prunus armeniaca L. 杏仁 杏仁|杏 To downbear qi and transform phlegm, relieve cough and calm asthma, moisten intestines and free stool./Cough, asthma and fullness due to external contraction cough, intestinal dry and constipation. 云南民族药物志：第四卷 bitter seed 回族/傈僳族/彝族/藏族
   疾病对应的化合物
化合物ID 化合物名 别名 分子式 分子质量 Smiles
TCMBANKIN058113 Butein 1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one; 2′,4′,3,4-Tetrahydroxychalcone; 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-, (2E)-; NCGC00163519-01; (E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one; NSC652892; AIDS057944; AC1NST6X; AIDS-057944; 3,4,2',4'-Tetrahydroxychalcone; ST5331397; 2',3,4,4'-Tetrahydrochalcone; 2',3,4,4'-Tetrahydroxychalcone; B178_SIGMA; butein ; MolMap_000005; Chalcone, 2',3,4,4'-tetrahydroxy- (7CI,8CI); EINECS 207-659-5; 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-; C08578; butein; 2',4',3,4-Tetrahydroxychalcone; 2′,3,4,4′-Tetrahydroxychalcone; Acrylophenone, 2',4'-dihydroxy-3-(3,4-dihydroxyphenyl)-; NCI60_018489; HSCI1_000162; 21849-70-7; (Z)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one; 487-52-5; 1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one C15H12O5 272.25 C1=CC(=C(C=C1C=CC(=O)C2=C(C=C(C=C2)O)O)O)O
   疾病对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE014645 SI - sucrase-isomaltase
TCMBANKGE000451 FGF19 - fibroblast growth factor 19
TCMBANKGE000785 G6PD G6PD1 glucose-6-phosphate dehydrogenase
TCMBANKGE001128 PRKAA2 AMPK; AMPK2; AMPKa2; PRKAA protein kinase AMP-activated catalytic subunit alpha 2
TCMBANKGE014003 IGFBP2 IBP2; IGF-BP53 insulin like growth factor binding protein 2
TCMBANKGE000429 CD36 BDPLT10; CHDS7; FAT; GP3B; GP4; GPIV; PASIV; SCARB3 CD36 molecule
TCMBANKGE000070 CAV1 BSCL3; CGL3; LCCNS; MSTP085; PPH3; VIP21 caveolin 1
TCMBANKGE001135 SREBF1 SREBP1; bHLHd1 sterol regulatory element binding transcription factor 1
TCMBANKGE005856 NEUROD1 BETA2; BHF-1; MODY6; NEUROD; bHLHa3 neuronal differentiation 1
TCMBANKGE012703 LIPC HDLCQ12; HL; HTGL; LIPH lipase C, hepatic type
TCMBANKGE011588 HNF4A FRTS4; HNF4; HNF4a7; HNF4a8; HNF4a9; HNF4alpha; MODY; MODY1; NR2A1; NR2A21; TCF; TCF14 hepatocyte nuclear factor 4 alpha
TCMBANKGE001753 GPX3 GPx-P; GSHPx-3; GSHPx-P glutathione peroxidase 3
TCMBANKGE000045 IRS2 IRS-2 insulin receptor substrate 2
TCMBANKGE001197 FOS AP-1; C-FOS; p55 Fos proto-oncogene, AP-1 transcription factor subunit
TCMBANKGE003099 CD163 M130; MM130; SCARI1 CD163 molecule
TCMBANKGE000261 INS IDDM; IDDM1; IDDM2; ILPR; IRDN; MODY10; PNDM4 insulin
TCMBANKGE004782 FIS1 CGI-135; TTC11 fission, mitochondrial 1
TCMBANKGE001130 BAD BBC2; BCL2L8 BCL2 associated agonist of cell death
TCMBANKGE001076 SOD2 GClnc1; IPO-B; IPOB; MNSOD; MVCD6; Mn-SOD superoxide dismutase 2
TCMBANKGE004391 MTNR1B FGQTL2; MEL-1B-R; MT2 melatonin receptor 1B
TCMBANKGE007365 IGFALS ACLSD; ALS insulin like growth factor binding protein acid labile subunit
TCMBANKGE001127 PRKAA1 AMPK; AMPKa1 protein kinase AMP-activated catalytic subunit alpha 1
TCMBANKGE009187 GCGR GGR; GL-R glucagon receptor
TCMBANKGE004116 PRDX3 AOP-1; AOP1; HBC189; MER5; PRO1748; SP-22; prx-III peroxiredoxin 3
TCMBANKGE013739 PRKCQ PRKCT; nPKC-theta protein kinase C theta
TCMBANKGE000653 TCF7L2 TCF-4; TCF4 transcription factor 7 like 2
TCMBANKGE000274 CCL2 GDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; SCYA2; SMC-CF C-C motif chemokine ligand 2
TCMBANKGE000241 CASP8 ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5 caspase 8
TCMBANKGE000230 ADIPOQ ACDC; ACRP30; ADIPQTL1; ADPN; APM-1; APM1; GBP28 adiponectin, C1Q and collagen domain containing
TCMBANKGE001074 ATM AT1; ATA; ATC; ATD; ATDC; ATE; TEL1; TELO1 ATM serine/threonine kinase
TCMBANKGE009255 COQ2 CL640; COQ10D1; MSA1; PHB:PPT coenzyme Q2, polyprenyltransferase
TCMBANKGE000247 SLC2A4 GLUT4 solute carrier family 2 member 4
TCMBANKGE001519 AGPAT2 1-AGPAT2; BSCL; BSCL1; LPAAB; LPAAT-beta 1-acylglycerol-3-phosphate O-acyltransferase 2
TCMBANKGE005777 AGTR2 AT2; ATGR2; MRX88 angiotensin II receptor type 2
TCMBANKGE005697 NSMCE2 C8orf36; MMS21; NSE2; ZMIZ7 NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE000633 ADRB2 ADRB2R; ADRBR; B2AR; BAR; BETA2AR adrenoceptor beta 2
TCMBANKGE001156 CASP3 CPP32; CPP32B; SCA-1 caspase 3
TCMBANKGE014768 CLCNKB CLCKB; ClC-K2; ClC-Kb chloride voltage-gated channel Kb
TCMBANKGE003661 ALMS1 ALSS ALMS1 centrosome and basal body associated protein
TCMBANKGE000989 ACACA ACAC; ACACAD; ACC; ACC1; ACCA acetyl-CoA carboxylase alpha
TCMBANKGE000882 SERPINE1 PAI; PAI-1; PAI1; PLANH1 serpin family E member 1
TCMBANKGE001038 SERPINF1 EPC-1; OI12; OI6; PEDF; PIG35 serpin family F member 1
TCMBANKGE000196 FAS ALPS1A; APO-1; APT1; CD95; FAS1; FASTM; TNFRSF6 Fas cell surface death receptor
TCMBANKGE000493 NR4A3 CHN; CSMF; MINOR; NOR1; TEC nuclear receptor subfamily 4 group A member 3
TCMBANKGE001184 RELA CMCU; NFKB3; p65 RELA proto-oncogene, NF-kB subunit
TCMBANKGE013819 PMCH MCH; ppMCH pro-melanin concentrating hormone
TCMBANKGE000859 PRKCD ALPS3; CVID9; MAY1; PKCD; nPKC-delta protein kinase C delta
TCMBANKGE001078 XBP1 TREB-5; TREB5; XBP-1; XBP2 X-box binding protein 1
TCMBANKGE002129 SELENOP SELP; SEPP; SEPP1; SeP selenoprotein P
TCMBANKGE000589 CD68 GP110; LAMP4; SCARD1 CD68 molecule
TCMBANKGE011056 BSCL2 GNG3LG; HMN5; PELD; SPG17 BSCL2 lipid droplet biogenesis associated, seipin
TCMBANKGE001107 NOS3 ECNOS; eNOS nitric oxide synthase 3
TCMBANKGE000243 LMNA CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; LMNL1; MADA; PRO1 lamin A/C
TCMBANKGE005746 XRCC4 SSMED X-ray repair cross complementing 4
TCMBANKGE006309 KCNMB1 BKbeta1; K(VCA)beta; SLO-BETA; hbeta1; hslo-beta; k(VCA)beta-1; slo-beta-1 potassium calcium-activated channel subfamily M regulatory beta subunit 1
TCMBANKGE012418 GPC6 OMIMD1 glypican 6
TCMBANKGE005732 SYN1 MRX50; SYN1a; SYN1b; SYNI synapsin I
TCMBANKGE013480 NEIL1 FPG1; NEI1; hFPG1 nei like DNA glycosylase 1
TCMBANKGE013216 CPE CPH carboxypeptidase E
TCMBANKGE014837 LEPR CD295; LEP-R; LEPRD; OB-R; OBR leptin receptor
TCMBANKGE000127 MFN2 CMT2A; CMT2A2; CMT2A2A; CMT2A2B; CPRP1; HMSN6A; HSG; MARF mitofusin 2
TCMBANKGE001138 LIPE AOMS4; FPLD6; HSL; LHS lipase E, hormone sensitive type
TCMBANKGE000246 FOXO1 FKH1; FKHR; FOXO1A forkhead box O1
TCMBANKGE014531 ENPP1 ARHR2; COLED; M6S1; NPP1; NPPS; PC-1; PCA1; PDNP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
TCMBANKGE013026 HSPD1 CPN60; GROEL; HLD4; HSP-60; HSP60; HSP65; HuCHA60; SPG13 heat shock protein family D (Hsp60) member 1
TCMBANKGE014110 C3 AHUS5; ARMD9; ASP; C3a; C3b; CPAMD1; HEL-S-62p complement C3
TCMBANKGE001182 SIRT1 SIR2; SIR2L1; SIR2alpha sirtuin 1
TCMBANKGE000587 ITGAM CD11B; CR3A; MAC-1; MAC1A; MO1A; SLEB6 integrin subunit alpha M
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE000706 ARG1 - arginase 1
TCMBANKGE011129 GH1 GH; GH-N; GHB5; GHN; IGHD1A; IGHD1B; IGHD2; hGH-N growth hormone 1
TCMBANKGE001158 LEP LEPD; OB; OBS leptin
TCMBANKGE005762 ACACB ACC2; ACCB; HACC275 acetyl-CoA carboxylase beta
TCMBANKGE001141 PPARA NR1C1; PPAR; PPARalpha; hPPAR peroxisome proliferator activated receptor alpha
TCMBANKGE013522 PRMT7 SBIDDS protein arginine methyltransferase 7
TCMBANKGE009992 ABCC8 ABC36; HHF1; HI; HRINS; MRP8; PHHI; PNDM3; SUR; SUR1; SUR1delta2; TNDM2 ATP binding cassette subfamily C member 8
TCMBANKGE014174 WRN RECQ3; RECQL2; RECQL3 WRN RecQ like helicase
TCMBANKGE011666 GPD2 GDH2; GPDM; mGPDH glycerol-3-phosphate dehydrogenase 2
TCMBANKGE001547 ALDH2 ALDH-E2; ALDHI; ALDM aldehyde dehydrogenase 2 family member
TCMBANKGE012168 SREBF2 SREBP-2; SREBP2; bHLHd2 sterol regulatory element binding transcription factor 2
TCMBANKGE000750 NR4A1 GFRP1; HMR; N10; NAK-1; NGFIB; NP10; NUR77; TR3 nuclear receptor subfamily 4 group A member 1
TCMBANKGE010818 MAPK8IP1 IB1; JIP-1; JIP1; PRKM8IP mitogen-activated protein kinase 8 interacting protein 1
TCMBANKGE011739 CTF1 CT-1; CT1 cardiotrophin 1
TCMBANKGE010789 HNF1A HNF-1A; HNF1; HNF4A; IDDM20; LFB1; MODY3; TCF-1; TCF1 HNF1 homeobox A
TCMBANKGE012260 TF HEL-S-71p; PRO1557; PRO2086; TFQTL1 transferrin
TCMBANKGE000932 AKT2 HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA AKT serine/threonine kinase 2
TCMBANKGE004483 METRNL - meteorin like, glial cell differentiation regulator
TCMBANKGE000525 PDX1 GSF; IDX-1; IPF1; IUF1; MODY4; PAGEN1; PDX-1; STF-1 pancreatic and duodenal homeobox 1
TCMBANKGE001879 STS ARSC; ARSC1; ASC; ES; SSDD; XLI steroid sulfatase
TCMBANKGE001042 PTPN1 PTP1B protein tyrosine phosphatase non-receptor type 1
TCMBANKGE002555 HSD11B1 11-DH; 11-beta-HSD1; CORTRD2; HDL; HSD11; HSD11B; HSD11L; SDR26C1 hydroxysteroid 11-beta dehydrogenase 1
TCMBANKGE010924 HSD3B2 HSD3B; HSDB; SDR11E2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
TCMBANKGE001861 BDKRB1 B1BKR; B1R; BDKRB2; BKB1R; BKR1; BRADYB1 bradykinin receptor B1
TCMBANKGE009080 PMM2 CDG1; CDG1a; CDGS; PMI; PMI1; PMM 2 phosphomannomutase 2
TCMBANKGE011547 APOC3 APOCIII apolipoprotein C3
TCMBANKGE009400 GNAS AHO; C20orf45; GNAS1; GPSA; GSA; GSP; NESP; PITA3; POH; SCG6; SgVI GNAS complex locus
TCMBANKGE014567 SLC12A3 NCC; NCCT; TSC solute carrier family 12 member 3
TCMBANKGE001149 PPARGC1A LEM6; PGC-1(alpha); PGC-1alpha; PGC-1v; PGC1; PGC1A; PPARGC1 PPARG coactivator 1 alpha
TCMBANKGE000866 PRKCB PKC-beta; PKCB; PKCI(2); PKCbeta; PRKCB1; PRKCB2 protein kinase C beta
TCMBANKGE007459 DBH DBM; ORTHYP1 dopamine beta-hydroxylase
TCMBANKGE000729 CASP1 ICE; IL1BC; P45 caspase 1
TCMBANKGE002566 TRIB3 C20orf97; NIPK; SINK; SKIP3; TRB3 tribbles pseudokinase 3
TCMBANKGE004090 ASXL2 ASXH2; SHAPNS ASXL transcriptional regulator 2
TCMBANKGE000566 HMGA1 HMG-R; HMGA1A; HMGIY high mobility group AT-hook 1
TCMBANKGE005975 ADORA1 RDC7 adenosine A1 receptor
TCMBANKGE000214 SCD FADS5; MSTP008; SCD1; SCDOS; hSCD1 stearoyl-CoA desaturase
TCMBANKGE009940 PARL PRO2207; PSARL; PSARL1; PSENIP2; RHBDS1 presenilin associated rhomboid like
TCMBANKGE003806 SIRT4 SIR2L4 sirtuin 4
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE001125 IGF1 IGF; IGF-I; IGFI; MGF insulin like growth factor 1
TCMBANKGE008060 SLC30A8 ZNT8; ZnT-8 solute carrier family 30 member 8
TCMBANKGE002728 CNTF HCNTF ciliary neurotrophic factor
TCMBANKGE001134 IRS1 HIRS-1 insulin receptor substrate 1
TCMBANKGE003673 SLC27A1 ACSVL5; FATP; FATP-1; FATP1 solute carrier family 27 member 1
TCMBANKGE001381 PAX4 KPD; MODY9 paired box 4
TCMBANKGE009491 CEP19 C3orf34; MOSPGF centrosomal protein 19
TCMBANKGE007543 INSR CD220; HHF5 insulin receptor
TCMBANKGE001201 MAPK3 ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; p44-ERK1; p44-MAPK mitogen-activated protein kinase 3
TCMBANKGE000782 GCK FGQTL3; GK; GLK; HHF3; HK4; HKIV; HXKP; LGLK; MODY2; PNDM1 glucokinase
TCMBANKGE002355 HAMP HEPC; HFE2B; LEAP1; PLTR hepcidin antimicrobial peptide
TCMBANKGE000244 ZMPSTE24 FACE-1; FACE1; HGPS; PRO1; STE24; Ste24p zinc metallopeptidase STE24
TCMBANKGE004669 IGF2BP2 IMP-2; IMP2; VICKZ2 insulin like growth factor 2 mRNA binding protein 2
TCMBANKGE000330 HMOX1 HMOX1D; HO-1; HSP32; bK286B10 heme oxygenase 1
TCMBANKGE015087 MRC1 CD206; CLEC13D; CLEC13DL; MMR; MRC1L1; bA541I19.1; hMR mannose receptor C-type 1
TCMBANKGE000046 PIK3R1 AGM7; GRB1; IMD36; p85; p85-ALPHA phosphoinositide-3-kinase regulatory subunit 1
TCMBANKGE001027 STK11 LKB1; PJS; hLKB1 serine/threonine kinase 11
TCMBANKGE000933 IKBKB IKK-beta; IKK2; IKKB; IMD15; IMD15A; IMD15B; NFKBIKB inhibitor of nuclear factor kappa B kinase subunit beta
TCMBANKGE010467 MC4R BMIQ20 melanocortin 4 receptor
TCMBANKGE013828 APLN APEL; XNPEP2 apelin
TCMBANKGE005364 SLC2A2 GLUT2 solute carrier family 2 member 2
TCMBANKGE000425 DRD1 DADR; DRD1A dopamine receptor D1
TCMBANKGE001080 AHR RP85; bHLHe76 aryl hydrocarbon receptor
TCMBANKGE000514 CNR1 CANN6; CB-R; CB1; CB1A; CB1K5; CB1R; CNR cannabinoid receptor 1
TCMBANKGE007296 PLAC8 C15; DGIC; PNAS-144; onzin placenta associated 8
TCMBANKGE002020 INPPL1 OPSMD; SHIP2 inositol polyphosphate phosphatase like 1
TCMBANKGE000414 CYP19A1 ARO; ARO1; CPV1; CYAR; CYP19; CYPXIX; P-450AROM cytochrome P450 family 19 subfamily A member 1
TCMBANKGE014740 PLTP BPIFE; HDLCQ9 phospholipid transfer protein
TCMBANKGE000459 PRKAR1A ACRDYS1; ADOHR; CAR; CNC; CNC1; PKR1; PPNAD1; PRKAR1; TSE1 protein kinase cAMP-dependent type I regulatory subunit alpha
TCMBANKGE000008 CD40 Bp50; CDW40; TNFRSF5; p50 CD40 molecule
TCMBANKGE001306 MSMO1 DESP4; ERG25; MCCPD; SC4MOL methylsterol monooxygenase 1
TCMBANKGE000829 FABP4 A-FABP; AFABP; ALBP; HEL-S-104; aP2 fatty acid binding protein 4
TCMBANKGE007040 ADCY3 AC-III; AC3; BMIQ19 adenylate cyclase 3
TCMBANKGE003210 POLD1 CDC2; CRCS10; MDPL; POLD DNA polymerase delta 1, catalytic subunit
TCMBANKGE006010 RETN ADSF; FIZZ3; RETN1; RSTN; XCP1 resistin
TCMBANKGE000197 KCNJ11 BIR; HHF2; IKATP; KIR6.2; MODY13; PHHI; PNDM2; TNDM3 potassium inwardly rectifying channel subfamily J member 11
TCMBANKGE007617 DOCK1 DOCK180; ced5 dedicator of cytokinesis 1

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