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疾病ID:TCMBANKDI000294
疾病名:Childhood Acute Myeloid Leukemia
MeSH_Name:Neoplasms
HPO_Name:-
UMLS_Name:Neoplastic Process
DO_Name:disease of anatomical entity; disease of cellular proliferation
疾病类型:disease
DisGeNET_Link:C0220621
MeSH_Link:C04
HPO_Link:-
UMLS_Link:T191
DO_Link:DOID:7; DOID:14566
HERB_ID:-
疾病对应的植物
| ID | 拉丁名 | 药名 | 药用植物名 | 功能与主治 | 来源 | 药用部位 | 使用民族 |
|---|
疾病对应的化合物
| 化合物ID | 化合物名 | 别名 | 分子式 | 分子质量 | Smiles |
|---|
疾病对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE002372 | IGFBP7 | AGM; FSTL2; IBP-7; IGFBP-7; IGFBP-7v; IGFBPRP1; MAC25; PSF; RAMSVPS; TAF | insulin like growth factor binding protein 7 |
| TCMBANKGE001111 | KIT | C-Kit; CD117; MASTC; PBT; SCFR | KIT proto-oncogene, receptor tyrosine kinase |
| TCMBANKGE012957 | NEO1 | IGDCC2; NGN; NTN1R2 | neogenin 1 |
| TCMBANKGE013729 | OPN1LW | CBBM; CBP; COD5; RCP; ROP | opsin 1, long wave sensitive |
| TCMBANKGE003578 | RARA | NR1B1; RAR | retinoic acid receptor alpha |
| TCMBANKGE014583 | RTEL1 | C20orf41; DKCA4; DKCB5; NHL; PFBMFT3; RTEL | regulator of telomere elongation helicase 1 |
| TCMBANKGE014689 | CD38 | ADPRC 1; ADPRC1 | CD38 molecule |
| TCMBANKGE006277 | MARCKSL1 | F52; MACMARCKS; MLP; MLP1; MRP | MARCKS like 1 |
| TCMBANKGE000117 | RUNX3 | AML2; CBFA3; PEBP2aC | RUNX family transcription factor 3 |
| TCMBANKGE003295 | GATA2 | DCML; IMD21; MONOMAC; NFE1B | GATA binding protein 2 |
| TCMBANKGE011145 | NSD1 | ARA267; KMT3B; SOTOS; SOTOS1; STO | nuclear receptor binding SET domain protein 1 |
| TCMBANKGE008479 | PICALM | CALM; CLTH; LAP | phosphatidylinositol binding clathrin assembly protein |
| TCMBANKGE006813 | TET2 | KIAA1546; MDS | tet methylcytosine dioxygenase 2 |
| TCMBANKGE001371 | KAT6B | GTPTS; MORF; MOZ2; MYST4; ZC2HC6B; qkf; querkopf | lysine acetyltransferase 6B |
| TCMBANKGE002102 | RUNX1T1 | AML1-MTG8; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2 | RUNX1 partner transcriptional co-repressor 1 |
| TCMBANKGE000660 | DNMT3B | ICF; ICF1; M.HsaIIIB | DNA methyltransferase 3 beta |
| TCMBANKGE000883 | MIR25 | MIRN25; hsa-mir-25; miR-25 | microRNA 25 |
| TCMBANKGE009264 | RPSA | 37LRP; 67LR; ICAS; LAMBR; LAMR1; LBP; LBP/p40; LRP; LRP/LR; NEM/1CHD4; SA; lamR; p40 | ribosomal protein SA |
| TCMBANKGE006374 | RARRES2 | HP10433; TIG2 | retinoic acid receptor responder 2 |
| TCMBANKGE006388 | EBF3 | COE3; EBF-3; HADDS; O/E-2; OE-2 | EBF transcription factor 3 |
| TCMBANKGE001103 | MDM2 | ACTFS; HDMX; LSKB; hdm2 | MDM2 proto-oncogene |
| TCMBANKGE000085 | EIF4A1 | DDX2A; EIF-4A; EIF4A; eIF-4A-I; eIF4A-I | eukaryotic translation initiation factor 4A1 |
| TCMBANKGE007799 | FLT3 | CD135; FLK-2; FLK2; STK1 | fms related receptor tyrosine kinase 3 |
| TCMBANKGE000683 | MIR34A | MIRN34A; miRNA34A; mir-34; mir-34a | microRNA 34a |
| TCMBANKGE000440 | HDAC1 | GON-10; HD1; KDAC1; RPD3; RPD3L1 | histone deacetylase 1 |
| TCMBANKGE010746 | ASXL1 | BOPS; MDS | ASXL transcriptional regulator 1 |
| TCMBANKGE000135 | CXCR4 | CD184; D2S201E; FB22; HM89; HSY3RR; LAP-3; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; WHIM; WHIMS | C-X-C motif chemokine receptor 4 |
| TCMBANKGE001017 | IDO1 | IDO; IDO-1; INDO | indoleamine 2,3-dioxygenase 1 |
| TCMBANKGE007957 | PRDM16 | CMD1LL; KMT8F; LVNC8; MEL1; PFM13 | PR/SET domain 16 |
| TCMBANKGE004454 | PDCD6 | ALG-2; ALG2; PEF1B | programmed cell death 6 |
| TCMBANKGE003699 | GSN | ADF; AGEL | gelsolin |
| TCMBANKGE004543 | TERF1 | PIN2; TRBF1; TRF; TRF1; hTRF1-AS; t-TRF1 | telomeric repeat binding factor 1 |
| TCMBANKGE000685 | ABL1 | ABL; BCR-ABL; CHDSKM; JTK7; bcr/abl; c-ABL; c-ABL1; p150; v-abl | ABL proto-oncogene 1, non-receptor tyrosine kinase |
| TCMBANKGE001165 | XIAP | API3; BIRC4; IAP-3; ILP1; MIHA; XLP2; hIAP-3; hIAP3 | X-linked inhibitor of apoptosis |
| TCMBANKGE001074 | ATM | AT1; ATA; ATC; ATD; ATDC; ATE; TEL1; TELO1 | ATM serine/threonine kinase |
| TCMBANKGE001013 | BIRC5 | API4; EPR-1 | baculoviral IAP repeat containing 5 |
| TCMBANKGE013528 | DERL1 | DER-1; DER1; derlin-1 | derlin 1 |
| TCMBANKGE000031 | DNMT3A | DNMT3A2; HESJAS; M.HsaIIIA; TBRS | DNA methyltransferase 3 alpha |
| TCMBANKGE004914 | MDM4 | BMFS6; HDMX; MDMX; MRP1 | MDM4 regulator of p53 |
| TCMBANKGE010712 | MME | CALLA; CD10; CMT2T; NEP; SCA43; SFE | membrane metalloendopeptidase |
| TCMBANKGE010134 | MYH11 | AAT4; FAA4; SMHC; SMMHC | myosin heavy chain 11 |
| TCMBANKGE003147 | SF3B1 | Hsh155; MDS; PRP10; PRPF10; SAP155; SF3b155 | splicing factor 3b subunit 1 |
| TCMBANKGE011085 | MEF2C | C5DELq14.3; DEL5q14.3 | myocyte enhancer factor 2C |
| TCMBANKGE000196 | FAS | ALPS1A; APO-1; APT1; CD95; FAS1; FASTM; TNFRSF6 | Fas cell surface death receptor |
| TCMBANKGE011334 | CSF3 | C17orf33; CSF3OS; GCSF | colony stimulating factor 3 |
| TCMBANKGE011002 | IKZF1 | CVID13; Hs.54452; IK1; IKAROS; LYF1; LyF-1; PPP1R92; PRO0758; ZNFN1A1 | IKAROS family zinc finger 1 |
| TCMBANKGE009448 | DDX10 | Dbp4; HRH-J8 | DEAD-box helicase 10 |
| TCMBANKGE006865 | GLIS2 | NKL; NPHP7 | GLIS family zinc finger 2 |
| TCMBANKGE000068 | VEGFC | Flt4-L; LMPH1D; LMPHM4; VRP | vascular endothelial growth factor C |
| TCMBANKGE001034 | TLR2 | CD282; TIL4 | toll like receptor 2 |
| TCMBANKGE000334 | GATA1 | ERYF1; GATA-1; GF-1; GF1; NF-E1; NFE1; XLANP; XLTDA; XLTT | GATA binding protein 1 |
| TCMBANKGE013170 | ELANE | ELA2; GE; HLE; HNE; NE; PMN-E; SCN1 | elastase, neutrophil expressed |
| TCMBANKGE001121 | CEBPA | C/EBP-alpha; CEBP | CCAAT enhancer binding protein alpha |
| TCMBANKGE007077 | PSIP1 | DFS70; LEDGF; PAIP; PSIP2; p52; p75 | PC4 and SFRS1 interacting protein 1 |
| TCMBANKGE000611 | CSF2 | CSF; GMCSF | colony stimulating factor 2 |
| TCMBANKGE000121 | KCNH2 | ERG-1; ERG1; H-ERG; HERG; HERG1; Kv11.1; LQT2; SQT1 | potassium voltage-gated channel subfamily H member 2 |
| TCMBANKGE001069 | MPO | - | myeloperoxidase |
| TCMBANKGE000262 | TBC1D9 | GRAMD9; MDR1 | TBC1 domain family member 9 |
| TCMBANKGE000078 | BRD4 | CAP; HUNK1; HUNKI; MCAP | bromodomain containing 4 |
| TCMBANKGE003686 | FANCB | FA2; FAAP90; FAAP95; FAB; FACB | FA complementation group B |
| TCMBANKGE003325 | ZNF382 | KS1 | zinc finger protein 382 |
| TCMBANKGE009726 | ERG | erg-3; p55 | ETS transcription factor ERG |
| TCMBANKGE001161 | IL2 | IL-2; TCGF; lymphokine | interleukin 2 |
| TCMBANKGE000619 | ASRGL1 | ALP; ALP1; CRASH | asparaginase and isoaspartyl peptidase 1 |
| TCMBANKGE000483 | TRPV2 | VRL; VRL-1; VRL1 | transient receptor potential cation channel subfamily V member 2 |
| TCMBANKGE005969 | THPO | MGDF; MKCSF; ML; MPLLG; THCYT1; TPO | thrombopoietin |
| TCMBANKGE002224 | U2AF1 | FP793; RN; RNU2AF1; U2AF35; U2AFBP | U2 small nuclear RNA auxiliary factor 1 |
| TCMBANKGE000877 | ABCG2 | ABC15; ABCP; BCRP; BCRP1; BMDP; CD338; CDw338; EST157481; GOUT1; MRX; MXR; MXR-1; MXR1; UAQTL1 | ATP binding cassette subfamily G member 2 (Junior blood group) |
| TCMBANKGE001178 | STAT3 | ADMIO; ADMIO1; APRF; HIES | signal transducer and activator of transcription 3 |
| TCMBANKGE003746 | CREBBP | CBP; KAT3A; MKHK1; RSTS; RSTS1 | CREB binding protein |
| TCMBANKGE000537 | ABCC1 | ABC29; ABCC; GS-X; MRP; MRP1 | ATP binding cassette subfamily C member 1 |
| TCMBANKGE010350 | CCR7 | BLR2; CC-CKR-7; CCR-7; CD197; CDw197; CMKBR7; EBI1 | C-C motif chemokine receptor 7 |
| TCMBANKGE000297 | JAK2 | JTK10; THCYT3 | Janus kinase 2 |
| TCMBANKGE015151 | HPGDS | GSTS; GSTS1; GSTS1-1; PGD2; PGDS | hematopoietic prostaglandin D synthase |
| TCMBANKGE007385 | NRAS | ALPS4; CMNS; N-ras; NCMS; NRAS1; NS6 | NRAS proto-oncogene, GTPase |
| TCMBANKGE002198 | DEK | D6S231E | DEK proto-oncogene |
| TCMBANKGE011010 | RUNX1 | AML1; AML1-EVI-1; AMLCR1; CBF2alpha; CBFA2; EVI-1; PEBP2aB; PEBP2alpha | RUNX family transcription factor 1 |
| TCMBANKGE004168 | SALL4 | DRRS; HSAL4; ZNF797 | spalt like transcription factor 4 |
| TCMBANKGE002600 | FUS | ALS6; ETM4; FUS1; HNRNPP2; POMP75; TLS | FUS RNA binding protein |
| TCMBANKGE004255 | CBFA2T3 | ETO2; MTG16; MTGR2; RUNX1T3; ZMYND4 | CBFA2/RUNX1 partner transcriptional co-repressor 3 |
| TCMBANKGE002894 | RHEBL1 | RHEBL1c | RHEB like 1 |
| TCMBANKGE000476 | NCOA2 | GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75 | nuclear receptor coactivator 2 |
| TCMBANKGE000277 | CD33 | SIGLEC-3; SIGLEC3; p67 | CD33 molecule |
| TCMBANKGE000482 | IDH1 | HEL-216; HEL-S-26; IDCD; IDH; IDP; IDPC; PICD | isocitrate dehydrogenase (NADP(+)) 1 |
| TCMBANKGE012446 | IL2RG | CD132; CIDX; IL-2RG; IMD4; P64; SCIDX; SCIDX1 | interleukin 2 receptor subunit gamma |
| TCMBANKGE014561 | ANXA2 | ANX2; ANX2L4; CAL1H; HEL-S-270; LIP2; LPC2; LPC2D; P36; PAP-IV | annexin A2 |
| TCMBANKGE012929 | EFS | CAS3; CASS3; EFS1; EFS2; HEFS; SIN | embryonal Fyn-associated substrate |
| TCMBANKGE000784 | CALM3 | CALM; CAM1; CAM2; CAMB; CPVT6; CaM; CaMIII; HEL-S-72; LQT16; PHKD; PHKD3 | calmodulin 3 |
| TCMBANKGE000569 | CD34 | - | CD34 molecule |
| TCMBANKGE006005 | GATA4 | ASD2; TACHD; TOF; VSD1 | GATA binding protein 4 |
| TCMBANKGE004668 | PIM2 | - | Pim-2 proto-oncogene, serine/threonine kinase |
| TCMBANKGE010779 | MN1 | CEBALID; MGCR; MGCR1; MGCR1-PEN; dJ353E16.2 | MN1 proto-oncogene, transcriptional regulator |
| TCMBANKGE006133 | PTPRA | HEPTP; HLPR; HPTPA; HPTPalpha; LRP; PTPA; PTPRL2; R-PTP-alpha; RPTPA | protein tyrosine phosphatase receptor type A |
| TCMBANKGE001100 | MIR155 | MIRN155; miRNA155; mir-155 | microRNA 155 |
| TCMBANKGE000150 | MIR192 | MIRN192; miR-192; miRNA192 | microRNA 192 |
| TCMBANKGE005339 | BCR | ALL; BCR1; CML; D22S11; D22S662; PHL | BCR activator of RhoGEF and GTPase |
| TCMBANKGE009074 | EBP | CDPX2; CHO2; CPX; CPXD; MEND | EBP cholestenol delta-isomerase |
| TCMBANKGE003496 | ATP6 | ATPase6; MTATP6 | ATP synthase F0 subunit 6 |
| TCMBANKGE000424 | WT1 | AWT1; GUD; NPHS4; WAGR; WIT-2; WT33 | WT1 transcription factor |
| TCMBANKGE010006 | EIF4A2 | BM-010; DDX2B; EIF4A; EIF4F; eIF-4A-II; eIF4A-II | eukaryotic translation initiation factor 4A2 |
| TCMBANKGE013825 | CBFB | PEBP2B | core-binding factor subunit beta |
| TCMBANKGE014442 | MVP | LRP; VAULT1 | major vault protein |
| TCMBANKGE008400 | BCL3 | BCL4; D19S37 | BCL3 transcription coactivator |
| TCMBANKGE000489 | IL3 | IL-3; MCGF; MULTI-CSF | interleukin 3 |
| TCMBANKGE009322 | IL3RA | CD123; IL3R; IL3RAY; IL3RX; IL3RY; hIL-3Ra | interleukin 3 receptor subunit alpha |
| TCMBANKGE002960 | NUP214 | CAIN; CAN; IIAE9 | nucleoporin 214 |
| TCMBANKGE010825 | NUP98 | ADIR2; NUP196; NUP96; Nup98-96 | nucleoporin 98 and 96 precursor |
| TCMBANKGE000729 | CASP1 | ICE; IL1BC; P45 | caspase 1 |
| TCMBANKGE000328 | PTPN11 | BPTP3; CFC; JMML; METCDS; NS1; PTP-1D; PTP2C; SH-PTP2; SH-PTP3; SHP2 | protein tyrosine phosphatase non-receptor type 11 |
| TCMBANKGE001686 | CTSL | CATL; CTSL1; MEP | cathepsin L |
| TCMBANKGE008571 | SRSF2 | PR264; SC-35; SC35; SFRS2; SFRS2A; SRp30b | serine and arginine rich splicing factor 2 |
| TCMBANKGE010969 | LRP1 | A2MR; APOER; APR; CD91; IGFBP-3R; IGFBP3R; IGFBP3R1; KPA; LRP; LRP1A; TGFBR5 | LDL receptor related protein 1 |
| TCMBANKGE008320 | ARHGEF1 | GEF1; IMD62; LBCL2; LSC; P115-RHOGEF; SUB1.5 | Rho guanine nucleotide exchange factor 1 |
| TCMBANKGE000891 | ABCC3 | ABC31; EST90757; MLP2; MOAT-D; MRP3; cMOAT2 | ATP binding cassette subfamily C member 3 |
| TCMBANKGE013894 | KAT6A | ARTHS; MOZ; MRD32; MYST-3; MYST3; RUNXBP2; ZC2HC6A; ZNF220 | lysine acetyltransferase 6A |
| TCMBANKGE003038 | TFPI2 | PP5; REF1; TFPI-2 | tissue factor pathway inhibitor 2 |
| TCMBANKGE003602 | CES2 | CE-2; CES2A1; PCE-2; iCE | carboxylesterase 2 |
| TCMBANKGE013662 | KLRK1 | CD314; D12S2489E; KLR; NKG2-D; NKG2D | killer cell lectin like receptor K1 |
| TCMBANKGE000361 | ERCC2 | COFS2; EM9; TFIIH; TTD; TTD1; XPD | ERCC excision repair 2, TFIIH core complex helicase subunit |
| TCMBANKGE004090 | ASXL2 | ASXH2; SHAPNS | ASXL transcriptional regulator 2 |
| TCMBANKGE008836 | MLLT11 | AF1Q | MLLT11 transcription factor 7 cofactor |
| TCMBANKGE003280 | CSF3R | CD114; GCSFR; SCN7 | colony stimulating factor 3 receptor |
| TCMBANKGE001056 | KRAS | C-K-RAS; C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; K-Ras; K-Ras 2; KI-RAS; KRAS1; KRAS2; NS; NS3; OES; RALD; RASK2; c-Ki-ras; c-Ki-ras2 | KRAS proto-oncogene, GTPase |
| TCMBANKGE012726 | MTTP | ABL; MTP | microsomal triglyceride transfer protein |
| TCMBANKGE000264 | ABCB1 | ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1 | ATP binding cassette subfamily B member 1 |
| TCMBANKGE012402 | NTRK1 | MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA | neurotrophic receptor tyrosine kinase 1 |
| TCMBANKGE000909 | GLI1 | GLI; PAPA8; PPD1 | GLI family zinc finger 1 |
| TCMBANKGE006621 | YWHAE | 14-3-3E; HEL2; KCIP-1; MDCR; MDS | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon |
| TCMBANKGE001096 | TLR4 | ARMD10; CD284; TLR-4; TOLL | toll like receptor 4 |
| TCMBANKGE001201 | MAPK3 | ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; p44-ERK1; p44-MAPK | mitogen-activated protein kinase 3 |
| TCMBANKGE001732 | ITGAL | CD11A; LFA-1; LFA1A | integrin subunit alpha L |
| TCMBANKGE007278 | SCT | - | secretin |
| TCMBANKGE008243 | ZNF296 | ZFP296; ZNF342 | zinc finger protein 296 |
| TCMBANKGE007627 | PAG1 | CBP; PAG | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 |
| TCMBANKGE003455 | ABCA3 | ABC-C; ABC3; EST111653; LBM180; SMDP3 | ATP binding cassette subfamily A member 3 |
| TCMBANKGE008873 | SBDS | CGI-97; SDS; SWDS | SBDS ribosome maturation factor |
| TCMBANKGE004587 | SLC25A1 | CMS23; CTP; D2L2AD; SEA; SLC20A3 | solute carrier family 25 member 1 |
| TCMBANKGE010433 | CSF1R | BANDDOS; C-FMS; CD115; CSF-1R; CSFR; FIM2; FMS; HDLS; M-CSF-R | colony stimulating factor 1 receptor |
| TCMBANKGE011776 | EIF4E | AUTS19; CBP; EIF4E1; EIF4EL1; EIF4F; eIF-4E | eukaryotic translation initiation factor 4E |
| TCMBANKGE007284 | MECOM | AML1-EVI-1; EVI1; KMT8E; MDS1; MDS1-EVI1; PRDM3; RUSAT2 | MDS1 and EVI1 complex locus |
| TCMBANKGE009774 | MSH3 | DUP; FAP4; MRP1 | mutS homolog 3 |
| TCMBANKGE007692 | GSTM1 | GST1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GTH4; GTM1; H-B; MU; MU-1 | glutathione S-transferase mu 1 |
| TCMBANKGE014757 | IDH2 | D2HGA2; ICD-M; IDH; IDHM; IDP; IDPM; mNADP-IDH | isocitrate dehydrogenase (NADP(+)) 2 |
| TCMBANKGE011881 | NPM1 | B23; NPM | nucleophosmin 1 |
| TCMBANKGE005458 | MT3 | GIF; GIFB; GRIF; ZnMT3 | metallothionein 3 |
| TCMBANKGE011910 | MNX1 | HB9; HLXB9; HOXHB9; SCRA1 | motor neuron and pancreas homeobox 1 |
| TCMBANKGE011732 | SOCS2 | CIS2; Cish2; SOCS-2; SSI-2; SSI2; STATI2 | suppressor of cytokine signaling 2 |
| TCMBANKGE014286 | WLS | C1orf139; EVI; GPR177; MRP; mig-14 | Wnt ligand secretion mediator |
| TCMBANKGE000350 | PML | MYL; PP8675; RNF71; TRIM19 | PML nuclear body scaffold |
| TCMBANKGE010293 | SETBP1 | MRD29; SEB | SET binding protein 1 |
| TCMBANKGE010848 | PAFAH1B1 | LIS1; LIS2; MDCR; MDS; NudF; PAFAH | platelet activating factor acetylhydrolase 1b regulatory subunit 1 |
| TCMBANKGE003960 | CD82 | 4F9; C33; GR15; IA4; KAI1; R2; SAR2; ST6; TSPAN27 | CD82 molecule |
| TCMBANKGE000467 | ABCC10 | EST182763; MRP7; SIMRP7 | ATP binding cassette subfamily C member 10 |
| TCMBANKGE003670 | ABCB6 | ABC; LAN; MTABC3; PRP; umat | ATP binding cassette subfamily B member 6 (Langereis blood group) |
| TCMBANKGE004410 | CPOX | COX; CPO; CPX; HCP | coproporphyrinogen oxidase |
| TCMBANKGE003672 | CALM1 | CALML2; CAM2; CAM3; CAMB; CAMC; CAMI; CAMIII; CPVT4; DD132; LQT14; PHKD; caM | calmodulin 1 |
| TCMBANKGE011843 | NOM1 | C7orf3; PPP1R113; SGD1 | nucleolar protein with MIF4G domain 1 |
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