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疾病ID:TCMBANKDI004508
疾病名:Keloid
MeSH_Name:Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
HPO_Name:Abnormality of the integument; Abnormality of connective tissue
UMLS_Name:Acquired Abnormality
DO_Name:-
疾病类型:disease
DisGeNET_Link:C0022548
MeSH_Link:C23; C17
HPO_Link:HP:0001574; HP:0003549
UMLS_Link:T020
DO_Link:-
HERB_ID:-
疾病对应的植物
| ID | 拉丁名 | 药名 | 药用植物名 | 功能与主治 | 来源 | 药用部位 | 使用民族 |
|---|
疾病对应的化合物
| 化合物ID | 化合物名 | 别名 | 分子式 | 分子质量 | Smiles |
|---|
疾病对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE001067 | S100A8 | 60B8AG; CAGA; CFAG; CGLA; CP-10; L1Ag; MA387; MIF; MRP8; NIF; P8 | S100 calcium binding protein A8 |
| TCMBANKGE014672 | FTH1 | FHC; FTH; FTHL6; HFE5; PIG15; PLIF | ferritin heavy chain 1 |
| TCMBANKGE001180 | SMAD3 | HSPC193; HsT17436; JV15-2; LDS1C; LDS3; MADH3 | SMAD family member 3 |
| TCMBANKGE000070 | CAV1 | BSCL3; CGL3; LCCNS; MSTP085; PPH3; VIP21 | caveolin 1 |
| TCMBANKGE008004 | ASPN | OS3; PLAP-1; PLAP1; SLRR1C | asporin |
| TCMBANKGE011688 | S100A10 | 42C; ANX2L; ANX2LG; CAL1L; CLP11; Ca[1]; GP11; P11; p10 | S100 calcium binding protein A10 |
| TCMBANKGE008239 | CRABP1 | CRABP; CRABP-I; CRABPI; RBP5 | cellular retinoic acid binding protein 1 |
| TCMBANKGE000742 | SMAD7 | CRCS3; MADH7; MADH8 | SMAD family member 7 |
| TCMBANKGE001213 | S100A12 | CAAF1; CAGC; CGRP; ENRAGE; MRP-6; MRP6; p6 | S100 calcium binding protein A12 |
| TCMBANKGE000567 | CDKN2A | ARF; CDK4I; CDKN2; CMM2; INK4; INK4A; MLM; MTS-1; MTS1; P14; P14ARF; P16; P16-INK4A; P16INK4; P16INK4A; P19; P19ARF; TP16 | cyclin dependent kinase inhibitor 2A |
| TCMBANKGE000896 | SFRP1 | FRP; FRP-1; FRP1; FrzA; SARP2 | secreted frizzled related protein 1 |
| TCMBANKGE013807 | ATP6AP2 | APT6M8-9; ATP6IP2; ATP6M8-9; CDG2R; ELDF10; HT028; M8-9; MRXE; MRXSH; MSTP009; PRR; RENR; XMRE; XPDS | ATPase H+ transporting accessory protein 2 |
| TCMBANKGE000162 | MMP13 | CLG3; MANDP1; MDST; MMP-13 | matrix metallopeptidase 13 |
| TCMBANKGE000903 | PTGS1 | COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS | prostaglandin-endoperoxide synthase 1 |
| TCMBANKGE002546 | PFN1 | ALS18 | profilin 1 |
| TCMBANKGE006480 | TNFAIP6 | TSG-6; TSG6 | TNF alpha induced protein 6 |
| TCMBANKGE002175 | COL3A1 | EDS4A; EDSVASC; PMGEDSV | collagen type III alpha 1 chain |
| TCMBANKGE004219 | CTSG | CATG; CG | cathepsin G |
| TCMBANKGE004283 | FBN2 | CCA; DA9; EOMD | fibrillin 2 |
| TCMBANKGE009021 | HLA-DQB1 | CELIAC1; HLA-DQB; IDDM1 | major histocompatibility complex, class II, DQ beta 1 |
| TCMBANKGE009133 | GDF9 | POF14 | growth differentiation factor 9 |
| TCMBANKGE000047 | AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | AKT serine/threonine kinase 1 |
| TCMBANKGE003252 | HTRA1 | ARMD7; CADASIL2; CARASIL; HtrA; L56; ORF480; PRSS11 | HtrA serine peptidase 1 |
| TCMBANKGE013160 | LAMA1 | LAMA; PTBHS; S-LAM-alpha | laminin subunit alpha 1 |
| TCMBANKGE003367 | CAPG | AFCP; HEL-S-66; MCP | capping actin protein, gelsolin like |
| TCMBANKGE014769 | POSTN | OSF-2; OSF2; PDLPOSTN; PN | periostin |
| TCMBANKGE012553 | TNC | 150-225; DFNA56; GMEM; GP; HXB; JI; TN; TN-C | tenascin C |
| TCMBANKGE014614 | SERPINH1 | AsTP3; CBP1; CBP2; HSP47; OI10; PIG14; PPROM; RA-A47; SERPINH2; gp46 | serpin family H member 1 |
| TCMBANKGE000128 | PRDX1 | MSP23; NKEF-A; NKEFA; PAG; PAGA; PAGB; PRX1; PRXI; TDPX2 | peroxiredoxin 1 |
| TCMBANKGE000305 | PIK3CD | APDS; IMD14; P110DELTA; PI3K; p110D | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta |
| TCMBANKGE000872 | IGF1R | CD221; IGFIR; IGFR; JTK13 | insulin like growth factor 1 receptor |
| TCMBANKGE012139 | BMP1 | OI13; PCOLC; PCP; PCP2; TLD | bone morphogenetic protein 1 |
| TCMBANKGE012773 | MIF | GIF; GLIF; MMIF | macrophage migration inhibitory factor |
| TCMBANKGE000544 | CXCR1 | C-C; C-C-CKR-1; CD128; CD181; CDw128a; CKR-1; CMKAR1; IL8R1; IL8RA; IL8RBA | C-X-C motif chemokine receptor 1 |
| TCMBANKGE000882 | SERPINE1 | PAI; PAI-1; PAI1; PLANH1 | serpin family E member 1 |
| TCMBANKGE000168 | NR3C1 | GCCR; GCR; GCRST; GR; GRL | nuclear receptor subfamily 3 group C member 1 |
| TCMBANKGE001038 | SERPINF1 | EPC-1; OI12; OI6; PEDF; PIG35 | serpin family F member 1 |
| TCMBANKGE000939 | DDR2 | MIG20a; NTRKR3; TKT; TYRO10; WRCN | discoidin domain receptor tyrosine kinase 2 |
| TCMBANKGE000166 | EP300 | KAT3B; MKHK2; RSTS2; p300 | E1A binding protein p300 |
| TCMBANKGE000606 | NRG1 | ARIA; GGF; GGF2; HGL; HRG; HRG1; HRGA; MST131; MSTP131; NDF; NRG1-IT2; SMDF | neuregulin 1 |
| TCMBANKGE001179 | SMAD2 | JV18; JV18-1; MADH2; MADR2; hMAD-2; hSMAD2 | SMAD family member 2 |
| TCMBANKGE000364 | SMN1 | BCD541; GEMIN1; SMA; SMA1; SMA2; SMA3; SMA4; SMA@; SMN; SMNT; T-BCD541; TDRD16A | survival of motor neuron 1, telomeric |
| TCMBANKGE000108 | COMP | EDM1; EPD1; MED; PSACH; THBS5; TSP5 | cartilage oligomeric matrix protein |
| TCMBANKGE009851 | FAP | DPPIV; FAPA; FAPalpha; SIMP | fibroblast activation protein alpha |
| TCMBANKGE015089 | LGALS1 | GAL1; GBP | galectin 1 |
| TCMBANKGE011228 | TPM1 | C15orf13; CMD1Y; CMH3; HEL-S-265; HTM-alpha; LVNC9; TMSA | tropomyosin 1 |
| TCMBANKGE001553 | FGG | - | fibrinogen gamma chain |
| TCMBANKGE000331 | CALCA | CALC1; CGRP; CGRP-I; CGRP-alpha; CGRP1; CT; KC; PCT | calcitonin related polypeptide alpha |
| TCMBANKGE001037 | MMP2 | CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1 | matrix metallopeptidase 2 |
| TCMBANKGE014927 | HSPA9 | CRP40; CSA; EVPLS; GRP-75; GRP75; HEL-S-124m; HSPA9B; MOT; MOT2; MTHSP75; PBP74; SAAN; SIDBA4 | heat shock protein family A (Hsp70) member 9 |
| TCMBANKGE009688 | MT1A | MT-1A; MT-IA; MT1; MT1S; MTC | metallothionein 1A |
| TCMBANKGE012468 | OSM | - | oncostatin M |
| TCMBANKGE000479 | TIMP1 | CLGI; EPA; EPO; HCI; TIMP; TIMP-1 | TIMP metallopeptidase inhibitor 1 |
| TCMBANKGE000202 | RUNX2 | AML3; CBF-alpha-1; CBFA1; CCD; CCD1; CLCD; OSF-2; OSF2; PEA2aA; PEBP2aA | RUNX family transcription factor 2 |
| TCMBANKGE001178 | STAT3 | ADMIO; ADMIO1; APRF; HIES | signal transducer and activator of transcription 3 |
| TCMBANKGE015138 | COL5A1 | EDSC; EDSCL1 | collagen type V alpha 1 chain |
| TCMBANKGE004181 | GLB1 | EBP; ELNR1; MPS4B | galactosidase beta 1 |
| TCMBANKGE001152 | WNT2 | INT1L1; IRP | Wnt family member 2 |
| TCMBANKGE003789 | HLA-DQA1 | CELIAC1; DQ-A1; DQA1; HLA-DQA | major histocompatibility complex, class II, DQ alpha 1 |
| TCMBANKGE003746 | CREBBP | CBP; KAT3A; MKHK1; RSTS; RSTS1 | CREB binding protein |
| TCMBANKGE000318 | HMGB1 | HMG-1; HMG1; HMG3; SBP-1 | high mobility group box 1 |
| TCMBANKGE014891 | MMP19 | CODA; MMP18; RASI-1 | matrix metallopeptidase 19 |
| TCMBANKGE000999 | FOXM1 | FKHL16; FOXM1A; FOXM1B; FOXM1C; HFH-11; HFH11; HNF-3; INS-1; MPHOSPH2; MPP-2; MPP2; PIG29; TRIDENT | forkhead box M1 |
| TCMBANKGE004432 | HBD | - | hypophosphatemic bone disease |
| TCMBANKGE004590 | NLRC5 | CLR16.1; NOD27; NOD4 | NLR family CARD domain containing 5 |
| TCMBANKGE000280 | VIM | - | vimentin |
| TCMBANKGE000224 | AGT | ANHU; SERPINA8; hFLT1 | angiotensinogen |
| TCMBANKGE000706 | ARG1 | - | arginase 1 |
| TCMBANKGE000730 | HSPB2 | HSP27; Hs.78846; LOH11CR1K; MKBP | heat shock protein family B (small) member 2 |
| TCMBANKGE007918 | DDR1 | CAK; CD167; DDR; EDDR1; HGK2; MCK10; NEP; NTRK4; PTK3; PTK3A; RTK6; TRKE | discoidin domain receptor tyrosine kinase 1 |
| TCMBANKGE009177 | CTHRC1 | - | collagen triple helix repeat containing 1 |
| TCMBANKGE001236 | ACTRT2 | ARPM2; ARPT2; Arp-T2; HARPM2 | actin related protein T2 |
| TCMBANKGE000959 | MYH9 | BDPLT6; DFNA17; EPSTS; FTNS; MATINS; MHA; NMHC-II-A; NMMHC-IIA; NMMHCA | myosin heavy chain 9 |
| TCMBANKGE000307 | PIK3CB | P110BETA; PI3K; PI3KBETA; PIK3C1 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta |
| TCMBANKGE000813 | DPP4 | ADABP; ADCP2; CD26; DPPIV; TP103 | dipeptidyl peptidase 4 |
| TCMBANKGE000296 | PRDX2 | HEL-S-2a; NKEF-B; NKEFB; PRP; PRX2; PRXII; PTX1; TDPX1; TPX1; TSA | peroxiredoxin 2 |
| TCMBANKGE001088 | SMAD4 | DPC4; JIP; MADH4; MYHRS | SMAD family member 4 |
| TCMBANKGE001495 | ARHGDIA | GDIA1; HEL-S-47e; NPHS8; RHOGDI; RHOGDI-1 | Rho GDP dissociation inhibitor alpha |
| TCMBANKGE000222 | EDN1 | ARCND3; ET1; HDLCQ7; PPET1; QME | endothelin 1 |
| TCMBANKGE005666 | DCN | CSCD; DSPG2; PG40; PGII; PGS2; SLRR1B | decorin |
| TCMBANKGE001697 | MMP1 | CLG; CLGN | matrix metallopeptidase 1 |
| TCMBANKGE012625 | BGN | DSPG1; MRLS; PG-S1; PGI; SEMDX; SLRR1A | biglycan |
| TCMBANKGE006834 | FTL | LFTD; NBIA3 | ferritin light chain |
| TCMBANKGE011987 | TP63 | AIS; B(p51A); B(p51B); EEC3; KET; LMS; NBP; OFC8; RHS; SHFM4; TP53CP; TP53L; TP73L; p40; p51; p53CP; p63; p73H; p73L | tumor protein p63 |
| TCMBANKGE002087 | ADAM33 | C20orf153; DJ964F7.1 | ADAM metallopeptidase domain 33 |
| TCMBANKGE011407 | PDGFA | PDGF-A; PDGF1 | platelet derived growth factor subunit A |
| TCMBANKGE012494 | HAS1 | HAS | hyaluronan synthase 1 |
| TCMBANKGE000449 | CCK | - | cholecystokinin |
| TCMBANKGE005646 | NEDD4 | NEDD4-1; RPF1 | NEDD4 E3 ubiquitin protein ligase |
| TCMBANKGE010297 | COL10A1 | - | collagen type X alpha 1 chain |
| TCMBANKGE000109 | ACTB | BRWS1; PS1TP5BP1 | actin beta |
| TCMBANKGE000806 | HSPA4 | APG-2; HEL-S-5a; HS24/P52; HSPH2; RY; hsp70; hsp70RY | heat shock protein family A (Hsp70) member 4 |
| TCMBANKGE008722 | APC | BTPS2; DESMD; DP2; DP2.5; DP3; GS; PPP1R46 | APC regulator of WNT signaling pathway |
| TCMBANKGE002743 | APOL1 | APO-L; APOL; APOL-I; FSGS4 | apolipoprotein L1 |
| TCMBANKGE005941 | FLNA | ABP-280; ABPX; CSBS; CVD1; FGS2; FLN; FLN-A; FLN1; FMD; MNS; NHBP; OPD; OPD1; OPD2; XLVD; XMVD | filamin A |
| TCMBANKGE005662 | ALB | HSA; PRO0883; PRO0903; PRO1341 | albumin |
| TCMBANKGE000469 | CTSD | CLN10; CPSD; HEL-S-130P | cathepsin D |
| TCMBANKGE000072 | CXCL12 | IRH; PBSF; SCYB12; SDF1; TLSF; TPAR1 | C-X-C motif chemokine ligand 12 |
| TCMBANKGE009742 | HLA-DRB1 | DRB1; HLA-DR1B; HLA-DRB; SS1 | major histocompatibility complex, class II, DR beta 1 |
| TCMBANKGE001094 | SIRT3 | SIR2L3 | sirtuin 3 |
| TCMBANKGE009633 | RAN | ARA24; Gsp1; TC4 | RAN, member RAS oncogene family |
| TCMBANKGE008164 | TGFBI | BIGH3; CDB1; CDG2; CDGG1; CSD; CSD1; CSD2; CSD3; EBMD; LCD1 | transforming growth factor beta induced |
| TCMBANKGE011344 | HUS1B | - | HUS1 checkpoint clamp component B |
| TCMBANKGE000251 | FGF2 | BFGF; FGF-2; FGFB; HBGF-2 | fibroblast growth factor 2 |
| TCMBANKGE005318 | S100A9 | 60B8AG; CAGB; CFAG; CGLB; L1AG; LIAG; MAC387; MIF; MRP14; NIF; P14 | S100 calcium binding protein A9 |
| TCMBANKGE006724 | REN | HNFJ2 | renin |
| TCMBANKGE007252 | IL22 | IL-21; IL-22; IL-D110; IL-TIF; ILTIF; TIFIL-23; TIFa; zcyto18 | interleukin 22 |
| TCMBANKGE000988 | HGF | DFNB39; F-TCF; HGFB; HPTA; SF | hepatocyte growth factor |
| TCMBANKGE001185 | PPARG | CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma | peroxisome proliferator activated receptor gamma |
| TCMBANKGE000240 | IL17A | CTLA-8; CTLA8; IL-17; IL-17A; IL17 | interleukin 17A |
| TCMBANKGE000884 | FN1 | CIG; ED-B; FINC; FN; FNZ; GFND; GFND2; LETS; MSF; SMDCF | fibronectin 1 |
| TCMBANKGE000286 | GSK3B | - | glycogen synthase kinase 3 beta |
| TCMBANKGE001060 | YAP1 | COB1; YAP; YAP2; YAP65; YKI | Yes1 associated transcriptional regulator |
| TCMBANKGE000885 | SPP1 | BNSP; BSPI; ETA-1; OPN | secreted phosphoprotein 1 |
| TCMBANKGE000100 | EIF5A | EIF-5A; EIF5A1; eIF-4D; eIF5AI | eukaryotic translation initiation factor 5A |
| TCMBANKGE010583 | SMN2 | BCD541; C-BCD541; GEMIN1; SMNC; TDRD16B | survival of motor neuron 2, centromeric |
| TCMBANKGE010394 | HNRNPH3 | 2H9; HNRPH3 | heterogeneous nuclear ribonucleoprotein H3 |
| TCMBANKGE008754 | H3P10 | p16 | H3 histone pseudogene 10 |
| TCMBANKGE007137 | SERPINB5 | PI5; maspin | serpin family B member 5 |
| TCMBANKGE001102 | MIR21 | MIRN21; hsa-mir-21; miR-21; miRNA21 | microRNA 21 |
| TCMBANKGE001045 | CCND1 | BCL1; D11S287E; PRAD1; U21B31 | cyclin D1 |
| TCMBANKGE000676 | SFN | YWHAS | stratifin |
| TCMBANKGE003940 | PTN | HARP; HB-GAM; HBBM; HBGF-8; HBGF8; HBNF; HBNF-1; NEGF1; OSF-1 | pleiotrophin |
| TCMBANKGE014763 | S100A4 | 18A2; 42A; CAPL; FSP1; MTS1; P9KA; PEL98 | S100 calcium binding protein A4 |
| TCMBANKGE008746 | ATP7A | DSMAX; MK; MNK; SMAX3 | ATPase copper transporting alpha |
| TCMBANKGE013914 | CLIC1 | CL1C1; CLCNL1; G6; NCC27 | chloride intracellular channel 1 |
| TCMBANKGE002571 | KLF10 | EGR-alpha; EGRA; TIEG; TIEG1 | Kruppel like factor 10 |
| TCMBANKGE014241 | MYH8 | DA7; MyHC-peri; MyHC-pn; gtMHC-F | myosin heavy chain 8 |
| TCMBANKGE000468 | CTSB | APPS; CPSB; RECEUP | cathepsin B |
| TCMBANKGE008183 | ACE | ACE1; CD143; DCP; DCP1 | angiotensin I converting enzyme |
| TCMBANKGE004104 | TINAGL1 | ARG1; LCN7; LIECG3; TINAGRP | tubulointerstitial nephritis antigen like 1 |
| TCMBANKGE009098 | CDH11 | CAD11; CDHOB; ESWS; OB; OSF-4 | cadherin 11 |
| TCMBANKGE011698 | ITGA5 | CD49e; FNRA; VLA-5; VLA5A | integrin subunit alpha 5 |
| TCMBANKGE012224 | VDR | NR1I1; PPP1R163 | vitamin D receptor |
| TCMBANKGE000306 | PIK3CG | PI3CG; PI3K; PI3Kgamma; PIK3; p110gamma; p120-PI3K | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma |
| TCMBANKGE000797 | HSPB1 | CMT2F; HEL-S-102; HMN2B; HS.76067; HSP27; HSP28; Hsp25; SRP27 | heat shock protein family B (small) member 1 |
| TCMBANKGE007742 | HSPB3 | DHMN2C; HMN2C; HSPL27 | heat shock protein family B (small) member 3 |
| TCMBANKGE009580 | SERPINB2 | HsT1201; PAI; PAI-2; PAI2; PLANH2 | serpin family B member 2 |
| TCMBANKGE000012 | TAGLN | SM22; SM22-alpha; SMCC; TAGLN1; WS3-10 | transgelin |
| TCMBANKGE000712 | COL1A1 | CAFYD; EDSARTH1; EDSC; OI1; OI2; OI3; OI4 | collagen type I alpha 1 chain |
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