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疾病ID:TCMBANKDI004604

疾病名:Lynch Syndrome

MeSH_Name:Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms; Nutritional and Metabolic Diseases

HPO_Name:-

UMLS_Name:Disease or Syndrome

DO_Name:genetic disease

疾病类型:disease

DisGeNET_Link:C4552100

MeSH_Link:C16; C06; C04; C18

HPO_Link:-

UMLS_Link:T047

DO_Link:DOID:630

HERB_ID:-

   疾病对应的植物
ID 拉丁名 药名 药用植物名 功能与主治 来源 药用部位 使用民族
   疾病对应的化合物
化合物ID 化合物名 别名 分子式 分子质量 Smiles
   疾病对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE001079 CYP1A1 AHH; AHRR; CP11; CYP1; CYPIA1; P1-450; P450-C; P450DX cytochrome P450 family 1 subfamily A member 1
TCMBANKGE000742 SMAD7 CRCS3; MADH7; MADH8 SMAD family member 7
TCMBANKGE012888 SGSM3 CIP85; MAP; RABGAP5; RUSC3; RUTBC3; RabGAP-5; rabGAPLP small G protein signaling modulator 3
TCMBANKGE014946 ALK CD246; NBLST3 ALK receptor tyrosine kinase
TCMBANKGE000567 CDKN2A ARF; CDK4I; CDKN2; CMM2; INK4; INK4A; MLM; MTS-1; MTS1; P14; P14ARF; P16; P16-INK4A; P16INK4; P16INK4A; P19; P19ARF; TP16 cyclin dependent kinase inhibitor 2A
TCMBANKGE014857 NPTN GP55; GP65; SDFR1; SDR1; np55; np65 neuroplastin
TCMBANKGE010781 BRCA2 BRCC2; BROVCA2; FACD; FAD; FAD1; FANCD; FANCD1; GLM3; PNCA2; XRCC11 BRCA2 DNA repair associated
TCMBANKGE007739 ELK3 ERP; NET; SAP-2; SAP2 ETS transcription factor ELK3
TCMBANKGE000173 BRAF B-RAF1; B-raf; BRAF1; NS7; RAFB1 B-Raf proto-oncogene, serine/threonine kinase
TCMBANKGE001089 PARP1 ADPRT; ADPRT 1; ADPRT1; ARTD1; PARP; PARP-1; PPOL; pADPRT-1 poly(ADP-ribose) polymerase 1
TCMBANKGE001103 MDM2 ACTFS; HDMX; LSKB; hdm2 MDM2 proto-oncogene
TCMBANKGE002980 CHEK2 CDS1; CHK2; HuCds1; LFS2; PP1425; RAD53; hCds1 checkpoint kinase 2
TCMBANKGE001074 ATM AT1; ATA; ATC; ATD; ATDC; ATE; TEL1; TELO1 ATM serine/threonine kinase
TCMBANKGE001147 CDH1 Arc-1; BCDS1; CD324; CDHE; ECAD; LCAM; UVO cadherin 1
TCMBANKGE000925 PCNA ATLD2 proliferating cell nuclear antigen
TCMBANKGE006891 SLCO6A1 CT48; GST; OATP-I; OATP6A1; OATPY solute carrier organic anion transporter family member 6A1
TCMBANKGE000987 COL11A2 DFNA13; DFNB53; FBCG2; HKE5; OSMEDA; OSMEDB; PARP; STL3 collagen type XI alpha 2 chain
TCMBANKGE000674 PDCD1 CD279; PD-1; PD1; SLEB2; hPD-1; hPD-l; hSLE1 programmed cell death 1
TCMBANKGE014344 NAT1 AAC1; MNAT; NAT-1; NATI N-acetyltransferase 1
TCMBANKGE000132 MAT2A MATA2; MATII; SAMS2 methionine adenosyltransferase 2A
TCMBANKGE000986 ERBB2 CD340; HER-2; HER-2/neu; HER2; MLN 19; NEU; NGL; TKR1 erb-b2 receptor tyrosine kinase 2
TCMBANKGE000323 BRCA1 BRCAI; BRCC1; BROVCA1; FANCS; IRIS; PNCA4; PPP1R53; PSCP; RNF53 BRCA1 DNA repair associated
TCMBANKGE002717 EMB GP70 embigin
TCMBANKGE009851 FAP DPPIV; FAPA; FAPalpha; SIMP fibroblast activation protein alpha
TCMBANKGE009256 SLC6A2 NAT1; NET; NET1; SLC6A5 solute carrier family 6 member 2
TCMBANKGE007141 MTHFR - methylenetetrahydrofolate reductase
TCMBANKGE014794 MUTYH MYH mutY DNA glycosylase
TCMBANKGE000036 SOCS1 CIS1; CISH1; JAB; SOCS-1; SSI-1; SSI1; TIP-3; TIP3 suppressor of cytokine signaling 1
TCMBANKGE000898 MYC MRTL; MYCC; bHLHe39; c-Myc MYC proto-oncogene, bHLH transcription factor
TCMBANKGE010973 EPCAM DIAR5; EGP-2; EGP314; EGP40; ESA; HNPCC8; KS1/4; KSA; M4S1; MIC18; MK-1; TACSTD1; TROP1 epithelial cell adhesion molecule
TCMBANKGE001557 XPA XP1; XPAC XPA, DNA damage recognition and repair factor
TCMBANKGE008130 RINT1 ILFS3; RINT-1 RAD50 interactor 1
TCMBANKGE007368 GSTP1 DFN7; FAEES3; GST3; GSTP; HEL-S-22; PI glutathione S-transferase pi 1
TCMBANKGE004398 CTCF CFAP108; FAP108; MRD21 CCCTC-binding factor
TCMBANKGE001084 EPHB1 ELK; EPHT2; Hek6; NET EPH receptor B1
TCMBANKGE008927 KAT2A GCN5; GCN5L2; PCAF-b; hGCN5 lysine acetyltransferase 2A
TCMBANKGE000728 MGMT - O-6-methylguanine-DNA methyltransferase
TCMBANKGE010448 RAD51C BROVCA3; FANCO; R51H3; RAD51L2 RAD51 paralog C
TCMBANKGE006345 GREM1 C15DUPq; CKTSF1B1; CRAC1; CRCS4; DAND2; DRM; DUP15q; GREMLIN; HMPS; HMPS1; IHG-2; MPSH; PIG2 gremlin 1, DAN family BMP antagonist
TCMBANKGE001051 MAP2K7 JNKK2; MAPKK7; MEK; MEK 7; MKK7; PRKMK7; SAPKK-4; SAPKK4 mitogen-activated protein kinase kinase 7
TCMBANKGE007487 VHL HRCA1; RCA1; VHL1; pVHL von Hippel-Lindau tumor suppressor
TCMBANKGE000200 CYP1B1 ASGD6; CP1B; CYPIB1; GLC3A; P4501B1 cytochrome P450 family 1 subfamily B member 1
TCMBANKGE010461 MSH6 GTBP; GTMBP; HNPCC5; HSAP; p160 mutS homolog 6
TCMBANKGE000388 ZEB1 AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3; TCF8; ZFHEP; ZFHX1A zinc finger E-box binding homeobox 1
TCMBANKGE001160 CD274 B7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1; hPD-L1 CD274 molecule
TCMBANKGE007602 MMP7 MMP-7; MPSL1; PUMP-1 matrix metallopeptidase 7
TCMBANKGE008240 MSH2 COCA1; FCC1; HNPCC; HNPCC1; LCFS2; hMSH2 mutS homolog 2
TCMBANKGE000445 CD44 CDW44; CSPG8; ECMR-III; HCELL; HUTCH-I; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1 CD44 molecule (Indian blood group)
TCMBANKGE002000 CTLA4 ALPS5; CD; CD152; CELIAC3; CTLA-4; GRD4; GSE; IDDM12 cytotoxic T-lymphocyte associated protein 4
TCMBANKGE008722 APC BTPS2; DESMD; DP2; DP2.5; DP3; GS; PPP1R46 APC regulator of WNT signaling pathway
TCMBANKGE002516 GSTK1 GST; GST 13-13; GST13; GST13-13; GSTK1-1; hGSTK1 glutathione S-transferase kappa 1
TCMBANKGE010271 NHS CTRCT40; CXN; SCML1 NHS actin remodeling regulator
TCMBANKGE000361 ERCC2 COFS2; EM9; TFIIH; TTD; TTD1; XPD ERCC excision repair 2, TFIIH core complex helicase subunit
TCMBANKGE010270 APEX1 APE; APE1; APEN; APEX; APX; HAP1; REF1 apurinic/apyrimidinic endodeoxyribonuclease 1
TCMBANKGE002431 ARID1A B120; BAF250; BAF250a; BM029; C1orf4; CSS2; ELD; MRD14; OSA1; P270; SMARCF1; hELD; hOSA1 AT-rich interaction domain 1A
TCMBANKGE005826 MUC16 CA125 mucin 16, cell surface associated
TCMBANKGE001056 KRAS C-K-RAS; C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; K-Ras; K-Ras 2; KI-RAS; KRAS1; KRAS2; NS; NS3; OES; RALD; RASK2; c-Ki-ras; c-Ki-ras2 KRAS proto-oncogene, GTPase
TCMBANKGE008175 PMS1 HNPCC3; MLH2; PMSL1; hPMS1 PMS1 homolog 1, mismatch repair system component
TCMBANKGE011172 MLH3 HNPCC7 mutL homolog 3
TCMBANKGE011953 MEN1 MEAI; SCG2 menin 1
TCMBANKGE010913 BRIP1 BACH1; FANCJ; OF BRCA1 interacting protein C-terminal helicase 1
TCMBANKGE008754 H3P10 p16 H3 histone pseudogene 10
TCMBANKGE014932 COMT HEL-S-98n catechol-O-methyltransferase
TCMBANKGE005995 PALB2 FANCN; PNCA3 partner and localizer of BRCA2
TCMBANKGE014100 PMS2 HNPCC4; MLH4; PMS2CL; PMSL2 PMS1 homolog 2, mismatch repair system component
TCMBANKGE000931 CYP17A1 CPT7; CYP17; P450C17; S17AH cytochrome P450 family 17 subfamily A member 1
TCMBANKGE015087 MRC1 CD206; CLEC13D; CLEC13DL; MMR; MRC1L1; bA541I19.1; hMR mannose receptor C-type 1
TCMBANKGE001027 STK11 LKB1; PJS; hLKB1 serine/threonine kinase 11
TCMBANKGE006877 MLH1 COCA2; FCC2; HNPCC; HNPCC2; hMLH1 mutL homolog 1
TCMBANKGE006516 AIP ARA9; FKBP16; FKBP37; PITA1; SMTPHN; XAP-2; XAP2 aryl hydrocarbon receptor interacting protein
TCMBANKGE011430 SEC63 DNAJC23; ERdj2; PCLD2; PRO2507; SEC63L SEC63 homolog, protein translocation regulator
TCMBANKGE004203 TGFBR2 AAT3; FAA3; LDS1B; LDS2; LDS2B; MFS2; RIIC; TAAD2; TBR-ii; TBRII; TGFR-2; TGFbeta-RII transforming growth factor beta receptor 2
TCMBANKGE005091 MAX bHLHd4 MYC associated factor X
TCMBANKGE009774 MSH3 DUP; FAP4; MRP1 mutS homolog 3
TCMBANKGE001795 PTPRG HPTPG; PTPG; R-PTP-GAMMA; RPTPG protein tyrosine phosphatase receptor type G
TCMBANKGE011990 CEACAM5 CD66e; CEA CEA cell adhesion molecule 5
TCMBANKGE006291 POLE CRCS12; FILS; IMAGEI; POLE1 DNA polymerase epsilon, catalytic subunit
TCMBANKGE000349 NBN AT-V1; AT-V2; ATV; NBS; NBS1; P95 nibrin
TCMBANKGE002950 ANXA10 ANX14 annexin A10
TCMBANKGE003210 POLD1 CDC2; CRCS10; MDPL; POLD DNA polymerase delta 1, catalytic subunit
TCMBANKGE007151 TIMP2 CSC-21K; DDC8 TIMP metallopeptidase inhibitor 2
TCMBANKGE005146 RNASEL PRCA1; RNS4 ribonuclease L
TCMBANKGE014458 RNF43 RNF124; SSPCS; URCC ring finger protein 43

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