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疾病ID:TCMBANKDI007182
疾病名:Juvenile Myelomonocytic Leukemia
MeSH_Name:Neoplasms; Hemic and Lymphatic Diseases
HPO_Name:Abnormality of the immune system; Neoplasm; Abnormality of blood and blood-forming tissues
UMLS_Name:Neoplastic Process
DO_Name:disease of anatomical entity; disease of cellular proliferation
疾病类型:disease
DisGeNET_Link:C0349639
MeSH_Link:C04; C15
HPO_Link:HP:0002715; HP:0002664; HP:0001871
UMLS_Link:T191
DO_Link:DOID:7; DOID:14566
HERB_ID:-
疾病对应的植物
| ID | 拉丁名 | 药名 | 药用植物名 | 功能与主治 | 来源 | 药用部位 | 使用民族 |
|---|
疾病对应的化合物
| 化合物ID | 化合物名 | 别名 | 分子式 | 分子质量 | Smiles |
|---|
疾病对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE002372 | IGFBP7 | AGM; FSTL2; IBP-7; IGFBP-7; IGFBP-7v; IGFBPRP1; MAC25; PSF; RAMSVPS; TAF | insulin like growth factor binding protein 7 |
| TCMBANKGE003913 | HBG2 | HBG-T1; TNCY | hemoglobin subunit gamma 2 |
| TCMBANKGE001111 | KIT | C-Kit; CD117; MASTC; PBT; SCFR | KIT proto-oncogene, receptor tyrosine kinase |
| TCMBANKGE001033 | FGFR1 | BFGFR; CD331; CEK; ECCL; FGFBR; FGFR-1; FLG; FLT-2; FLT2; HBGFR; HH2; HRTFDS; KAL2; N-SAM; OGD; bFGF-R-1 | fibroblast growth factor receptor 1 |
| TCMBANKGE013729 | OPN1LW | CBBM; CBP; COD5; RCP; ROP | opsin 1, long wave sensitive |
| TCMBANKGE001164 | RAF1 | CMD1NN; CRAF; NS5; Raf-1; c-Raf | Raf-1 proto-oncogene, serine/threonine kinase |
| TCMBANKGE014689 | CD38 | ADPRC 1; ADPRC1 | CD38 molecule |
| TCMBANKGE003295 | GATA2 | DCML; IMD21; MONOMAC; NFE1B | GATA binding protein 2 |
| TCMBANKGE009092 | F9 | F9 p22; FIX; HEMB; P19; PTC; THPH8 | coagulation factor IX |
| TCMBANKGE006813 | TET2 | KIAA1546; MDS | tet methylcytosine dioxygenase 2 |
| TCMBANKGE000660 | DNMT3B | ICF; ICF1; M.HsaIIIB | DNA methyltransferase 3 beta |
| TCMBANKGE012888 | SGSM3 | CIP85; MAP; RABGAP5; RUSC3; RUTBC3; RabGAP-5; rabGAPLP | small G protein signaling modulator 3 |
| TCMBANKGE000171 | DNMT1 | ADCADN; AIM; CXXC9; DNMT; HSN1E; MCMT; m.HsaI | DNA methyltransferase 1 |
| TCMBANKGE014946 | ALK | CD246; NBLST3 | ALK receptor tyrosine kinase |
| TCMBANKGE000567 | CDKN2A | ARF; CDK4I; CDKN2; CMM2; INK4; INK4A; MLM; MTS-1; MTS1; P14; P14ARF; P16; P16-INK4A; P16INK4; P16INK4A; P19; P19ARF; TP16 | cyclin dependent kinase inhibitor 2A |
| TCMBANKGE010791 | MVD | FP17780; MDDase; MPD; POROK7 | mevalonate diphosphate decarboxylase |
| TCMBANKGE000827 | CBL | C-CBL; CBL2; FRA11B; NSLL; RNF55 | Cbl proto-oncogene |
| TCMBANKGE000173 | BRAF | B-RAF1; B-raf; BRAF1; NS7; RAFB1 | B-Raf proto-oncogene, serine/threonine kinase |
| TCMBANKGE007041 | RAC2 | EN-7; Gx; HSPC022; p21-Rac2 | Rac family small GTPase 2 |
| TCMBANKGE001089 | PARP1 | ADPRT; ADPRT 1; ADPRT1; ARTD1; PARP; PARP-1; PPOL; pADPRT-1 | poly(ADP-ribose) polymerase 1 |
| TCMBANKGE000953 | PTPN6 | HCP; HCPH; HPTP1C; PTP-1C; SH-PTP1; SHP-1; SHP-1L; SHP1 | protein tyrosine phosphatase non-receptor type 6 |
| TCMBANKGE013940 | SOAT1 | ACACT; ACAT; ACAT-1; ACAT1; SOAT; STAT | sterol O-acyltransferase 1 |
| TCMBANKGE000818 | ROS1 | MCF3; ROS; c-ros-1 | ROS proto-oncogene 1, receptor tyrosine kinase |
| TCMBANKGE007799 | FLT3 | CD135; FLK-2; FLK2; STK1 | fms related receptor tyrosine kinase 3 |
| TCMBANKGE010746 | ASXL1 | BOPS; MDS | ASXL transcriptional regulator 1 |
| TCMBANKGE004893 | TNK2 | ACK; ACK-1; ACK1; p21cdc42Hs | tyrosine kinase non receptor 2 |
| TCMBANKGE007397 | SH2B3 | IDDM20; LNK | SH2B adaptor protein 3 |
| TCMBANKGE000135 | CXCR4 | CD184; D2S201E; FB22; HM89; HSY3RR; LAP-3; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; WHIM; WHIMS | C-X-C motif chemokine receptor 4 |
| TCMBANKGE000245 | CYBB | AMCBX2; CGD; GP91-1; GP91-PHOX; GP91PHOX; IMD34; NOX2; p91-PHOX | cytochrome b-245 beta chain |
| TCMBANKGE000685 | ABL1 | ABL; BCR-ABL; CHDSKM; JTK7; bcr/abl; c-ABL; c-ABL1; p150; v-abl | ABL proto-oncogene 1, non-receptor tyrosine kinase |
| TCMBANKGE000047 | AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | AKT serine/threonine kinase 1 |
| TCMBANKGE012347 | PPP1R12C | AAVS1; LENG3; MBS85; p84; p85 | protein phosphatase 1 regulatory subunit 12C |
| TCMBANKGE000031 | DNMT3A | DNMT3A2; HESJAS; M.HsaIIIA; TBRS | DNA methyltransferase 3 alpha |
| TCMBANKGE000134 | EPO | DBAL; ECYT5; EP; MVCD2 | erythropoietin |
| TCMBANKGE000305 | PIK3CD | APDS; IMD14; P110DELTA; PI3K; p110D | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta |
| TCMBANKGE000987 | COL11A2 | DFNA13; DFNB53; FBCG2; HKE5; OSMEDA; OSMEDB; PARP; STL3 | collagen type XI alpha 2 chain |
| TCMBANKGE010263 | WAS | IMD2; SCNX; THC; THC1; WASP; WASPA | WASP actin nucleation promoting factor |
| TCMBANKGE009859 | HOXA11 | HOX1; HOX1I; RUSAT1 | homeobox A11 |
| TCMBANKGE001203 | MAPK1 | ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK | mitogen-activated protein kinase 1 |
| TCMBANKGE013168 | PPP1R13B | ASPP1; p53BP2-like; p85 | protein phosphatase 1 regulatory subunit 13B |
| TCMBANKGE003147 | SF3B1 | Hsh155; MDS; PRP10; PRPF10; SAP155; SF3b155 | splicing factor 3b subunit 1 |
| TCMBANKGE000960 | STAT5A | MGF; STAT5 | signal transducer and activator of transcription 5A |
| TCMBANKGE006061 | THBD | AHUS6; BDCA3; CD141; THPH12; THRM; TM | thrombomodulin |
| TCMBANKGE011756 | GAB2 | - | GRB2 associated binding protein 2 |
| TCMBANKGE000477 | EZH2 | ENX-1; ENX1; EZH2b; KMT6; KMT6A; WVS; WVS2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| TCMBANKGE001257 | RET | CDHF12; CDHR16; HSCR1; MEN2A; MEN2B; MTC1; PTC; RET-ELE1 | ret proto-oncogene |
| TCMBANKGE010136 | PEBP1 | HCNP; HCNPpp; HEL-210; HEL-S-34; HEL-S-96; PBP; PEBP; PEBP-1; RKIP | phosphatidylethanolamine binding protein 1 |
| TCMBANKGE000033 | SOS1 | GF1; GGF1; GINGF; HGF; NS4; SOS-1 | SOS Ras/Rac guanine nucleotide exchange factor 1 |
| TCMBANKGE002467 | LIN28B | CSDD2 | lin-28 homolog B |
| TCMBANKGE004896 | RRAS2 | NS12; TC21 | RAS related 2 |
| TCMBANKGE000611 | CSF2 | CSF; GMCSF | colony stimulating factor 2 |
| TCMBANKGE004267 | REG1A | ICRF; P19; PSP; PSPS; PSPS1; PTP; REG | regenerating family member 1 alpha |
| TCMBANKGE001153 | EPHB2 | BDPLT22; CAPB; DRT; EK5; EPHT3; ERK; Hek5; PCBC; Tyro5 | EPH receptor B2 |
| TCMBANKGE003061 | BCL11A | BCL11A-L; BCL11A-S; BCL11A-XL; BCL11a-M; CTIP1; DILOS; EVI9; HBFQTL5; ZNF856 | BAF chromatin remodeling complex subunit BCL11A |
| TCMBANKGE000890 | FUT1 | H; HH; HSC | fucosyltransferase 1 (H blood group) |
| TCMBANKGE000116 | ZHX2 | AFR1; RAF | zinc fingers and homeoboxes 2 |
| TCMBANKGE004317 | RASA4 | CAPRI; GAPL | RAS p21 protein activator 4 |
| TCMBANKGE004699 | EBI3 | IL-27B; IL27B; IL35B | Epstein-Barr virus induced 3 |
| TCMBANKGE003686 | FANCB | FA2; FAAP90; FAAP95; FAB; FACB | FA complementation group B |
| TCMBANKGE012549 | ARHGEF7 | BETA-PIX; COOL-1; COOL1; Nbla10314; P50; P50BP; P85; P85COOL1; P85SPR; PAK3; PIXB | Rho guanine nucleotide exchange factor 7 |
| TCMBANKGE011502 | KAT7 | HBO1; HBOA; MYST2; ZC2HC7 | lysine acetyltransferase 7 |
| TCMBANKGE006806 | FUT4 | CD15; ELFT; FCT3A; FUC-TIV; FUTIV; LeX; SSEA-1 | fucosyltransferase 4 |
| TCMBANKGE005969 | THPO | MGDF; MKCSF; ML; MPLLG; THCYT1; TPO | thrombopoietin |
| TCMBANKGE011434 | THY1 | CD90; CDw90 | Thy-1 cell surface antigen |
| TCMBANKGE000898 | MYC | MRTL; MYCC; bHLHe39; c-Myc | MYC proto-oncogene, bHLH transcription factor |
| TCMBANKGE002224 | U2AF1 | FP793; RN; RNU2AF1; U2AF35; U2AFBP | U2 small nuclear RNA auxiliary factor 1 |
| TCMBANKGE001178 | STAT3 | ADMIO; ADMIO1; APRF; HIES | signal transducer and activator of transcription 3 |
| TCMBANKGE003746 | CREBBP | CBP; KAT3A; MKHK1; RSTS; RSTS1 | CREB binding protein |
| TCMBANKGE010350 | CCR7 | BLR2; CC-CKR-7; CCR-7; CD197; CDw197; CMKBR7; EBI1 | C-C motif chemokine receptor 7 |
| TCMBANKGE000297 | JAK2 | JTK10; THCYT3 | Janus kinase 2 |
| TCMBANKGE007385 | NRAS | ALPS4; CMNS; N-ras; NCMS; NRAS1; NS6 | NRAS proto-oncogene, GTPase |
| TCMBANKGE007797 | KITLG | DCUA; DFNA69; FPH2; FPHH; KL-1; Kitl; MGF; SCF; SF; SHEP7; SLF | KIT ligand |
| TCMBANKGE001171 | SRC | ASV; SRC1; THC6; c-SRC; p60-Src | SRC proto-oncogene, non-receptor tyrosine kinase |
| TCMBANKGE009185 | MEFV | FMF; MEF; TRIM20 | MEFV innate immuity regulator, pyrin |
| TCMBANKGE011010 | RUNX1 | AML1; AML1-EVI-1; AMLCR1; CBF2alpha; CBFA2; EVI-1; PEBP2aB; PEBP2alpha | RUNX family transcription factor 1 |
| TCMBANKGE003122 | NRP2 | NP2; NPN2; PRO2714; VEGF165R2 | neuropilin 2 |
| TCMBANKGE004266 | AR | AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM | androgen receptor |
| TCMBANKGE000706 | ARG1 | - | arginase 1 |
| TCMBANKGE000812 | REL | C-Rel | REL proto-oncogene, NF-kB subunit |
| TCMBANKGE001154 | CREB1 | CREB; CREB-1 | cAMP responsive element binding protein 1 |
| TCMBANKGE000959 | MYH9 | BDPLT6; DFNA17; EPSTS; FTNS; MATINS; MHA; NMHC-II-A; NMMHC-IIA; NMMHCA | myosin heavy chain 9 |
| TCMBANKGE000141 | CALR | CRT; HEL-S-99n; RO; SSA; cC1qR | calreticulin |
| TCMBANKGE000307 | PIK3CB | P110BETA; PI3K; PI3KBETA; PIK3C1 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta |
| TCMBANKGE010713 | RAP1GAP | RAP1GA1; RAP1GAP1; RAP1GAPII; RAPGAP | RAP1 GTPase activating protein |
| TCMBANKGE010402 | NF1 | NFNS; VRNF; WSS | neurofibromin 1 |
| TCMBANKGE011801 | CDKN2D | INK4D; p19; p19-INK4D | cyclin dependent kinase inhibitor 2D |
| TCMBANKGE014748 | NACA | HSD48; NAC-alpha; NACA1; skNAC | nascent polypeptide associated complex subunit alpha |
| TCMBANKGE012446 | IL2RG | CD132; CIDX; IL-2RG; IMD4; P64; SCIDX; SCIDX1 | interleukin 2 receptor subunit gamma |
| TCMBANKGE000422 | MIR15A | MIRN15A; hsa-mir-15a; miRNA15A; mir-15a | microRNA 15a |
| TCMBANKGE014561 | ANXA2 | ANX2; ANX2L4; CAL1H; HEL-S-270; LIP2; LPC2; LPC2D; P36; PAP-IV | annexin A2 |
| TCMBANKGE000569 | CD34 | - | CD34 molecule |
| TCMBANKGE008208 | RRAS | R-Ras | RAS related |
| TCMBANKGE003195 | PDGFRB | CD140B; IBGC4; IMF1; JTK12; KOGS; PDGFR; PDGFR-1; PDGFR1; PENTT | platelet derived growth factor receptor beta |
| TCMBANKGE001051 | MAP2K7 | JNKK2; MAPKK7; MEK; MEK 7; MKK7; PRKMK7; SAPKK-4; SAPKK4 | mitogen-activated protein kinase kinase 7 |
| TCMBANKGE000652 | STAT5B | STAT5 | signal transducer and activator of transcription 5B |
| TCMBANKGE014042 | INPP5D | SHIP; SHIP-1; SHIP1; SIP-145; hp51CN; p150Ship | inositol polyphosphate-5-phosphatase D |
| TCMBANKGE014212 | HBG1 | HBG-T2; HBGA; HBGR; HSGGL1; PRO2979 | hemoglobin subunit gamma 1 |
| TCMBANKGE012670 | ELL | C19orf17; ELL1; MEN; PPP1R68 | elongation factor for RNA polymerase II |
| TCMBANKGE007942 | OSBP2 | HLM; ORP-4; ORP4; OSBPL1; OSBPL4 | oxysterol binding protein 2 |
| TCMBANKGE001199 | PDGFRA | CD140A; PDGFR-2; PDGFR2 | platelet derived growth factor receptor alpha |
| TCMBANKGE006609 | RIT1 | NS8; RIBB; RIT; ROC1 | Ras like without CAAX 1 |
| TCMBANKGE012378 | MUL1 | C1orf166; GIDE; MAPL; MULAN; RNF218 | mitochondrial E3 ubiquitin protein ligase 1 |
| TCMBANKGE009819 | MYH10 | NMMHC-IIB; NMMHCB | myosin heavy chain 10 |
| TCMBANKGE000041 | IRF1 | IRF-1; MAR | interferon regulatory factor 1 |
| TCMBANKGE005339 | BCR | ALL; BCR1; CML; D22S11; D22S662; PHL | BCR activator of RhoGEF and GTPase |
| TCMBANKGE000489 | IL3 | IL-3; MCGF; MULTI-CSF | interleukin 3 |
| TCMBANKGE009322 | IL3RA | CD123; IL3R; IL3RAY; IL3RX; IL3RY; hIL-3Ra | interleukin 3 receptor subunit alpha |
| TCMBANKGE003065 | NXT1 | MTR2; P15 | nuclear transport factor 2 like export factor 1 |
| TCMBANKGE006898 | NELL2 | NRP2 | neural EGFL like 2 |
| TCMBANKGE010825 | NUP98 | ADIR2; NUP196; NUP96; Nup98-96 | nucleoporin 98 and 96 precursor |
| TCMBANKGE000328 | PTPN11 | BPTP3; CFC; JMML; METCDS; NS1; PTP-1D; PTP2C; SH-PTP2; SH-PTP3; SHP2 | protein tyrosine phosphatase non-receptor type 11 |
| TCMBANKGE009874 | CDKN2B | CDK4I; INK4B; MTS2; P15; TP15; p15INK4b | cyclin dependent kinase inhibitor 2B |
| TCMBANKGE008571 | SRSF2 | PR264; SC-35; SC35; SFRS2; SFRS2A; SRp30b | serine and arginine rich splicing factor 2 |
| TCMBANKGE013432 | TRIM33 | ECTO; PTC7; RFG7; TF1G; TIF1G; TIF1GAMMA; TIFGAMMA | tripartite motif containing 33 |
| TCMBANKGE006100 | CSF2RA | CD116; CDw116; CSF2R; CSF2RAX; CSF2RAY; CSF2RX; CSF2RY; GM-CSF-R-alpha; GMCSFR; GMCSFR-alpha; GMR; GMR-alpha; SMDP4; alphaGMR | colony stimulating factor 2 receptor subunit alpha |
| TCMBANKGE009913 | ARHGAP26 | GRAF; GRAF1; OPHN1L; OPHN1L1 | Rho GTPase activating protein 26 |
| TCMBANKGE006006 | RAG2 | RAG-2 | recombination activating 2 |
| TCMBANKGE004706 | MOGS | CDG2B; CWH41; DER7; GCS1 | mannosyl-oligosaccharide glucosidase |
| TCMBANKGE001056 | KRAS | C-K-RAS; C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; K-Ras; K-Ras 2; KI-RAS; KRAS1; KRAS2; NS; NS3; OES; RALD; RASK2; c-Ki-ras; c-Ki-ras2 | KRAS proto-oncogene, GTPase |
| TCMBANKGE013441 | SUB1 | P15; PC4; p14 | SUB1 regulator of transcription |
| TCMBANKGE008754 | H3P10 | p16 | H3 histone pseudogene 10 |
| TCMBANKGE013001 | SMC1A | CDLS2; DXS423E; EIEE85; SB1.8; SMC1; SMC1L1; SMC1alpha; SMCB | structural maintenance of chromosomes 1A |
| TCMBANKGE000040 | IRF2 | IRF-2 | interferon regulatory factor 2 |
| TCMBANKGE001953 | TEK | CD202B; GLC3E; TIE-2; TIE2; VMCM; VMCM1 | TEK receptor tyrosine kinase |
| TCMBANKGE011969 | AKAP12 | AKAP250; SSeCKS | A-kinase anchoring protein 12 |
| TCMBANKGE003972 | SPECC1 | CYTSB; HCMOGT-1; HCMOGT1; NSP | sperm antigen with calponin homology and coiled-coil domains 1 |
| TCMBANKGE007278 | SCT | - | secretin |
| TCMBANKGE004236 | RNASE3 | ECP; RAF1; RNS3 | ribonuclease A family member 3 |
| TCMBANKGE015002 | IL10RA | CD210; CD210a; CDW210A; HIL-10R; IL-10R1; IL10R | interleukin 10 receptor subunit alpha |
| TCMBANKGE008580 | ETNK1 | EKI; EKI 1; EKI1; Nbla10396 | ethanolamine kinase 1 |
| TCMBANKGE007627 | PAG1 | CBP; PAG | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 |
| TCMBANKGE000046 | PIK3R1 | AGM7; GRB1; IMD36; p85; p85-ALPHA | phosphoinositide-3-kinase regulatory subunit 1 |
| TCMBANKGE008830 | JAK3 | JAK-3; JAK3_HUMAN; JAKL; L-JAK; LJAK | Janus kinase 3 |
| TCMBANKGE000089 | PIK3R2 | MPPH; MPPH1; P85B; p85; p85-BETA | phosphoinositide-3-kinase regulatory subunit 2 |
| TCMBANKGE000306 | PIK3CG | PI3CG; PI3K; PI3Kgamma; PIK3; p110gamma; p120-PI3K | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma |
| TCMBANKGE011776 | EIF4E | AUTS19; CBP; EIF4E1; EIF4EL1; EIF4F; eIF-4E | eukaryotic translation initiation factor 4E |
| TCMBANKGE007284 | MECOM | AML1-EVI-1; EVI1; KMT8E; MDS1; MDS1-EVI1; PRDM3; RUSAT2 | MDS1 and EVI1 complex locus |
| TCMBANKGE015165 | KDM1A | AOF2; BHC110; CPRF; KDM1; LSD1 | lysine demethylase 1A |
| TCMBANKGE004637 | IL18R1 | CD218a; CDw218a; IL-18R-alpha; IL-18Ralpha; IL-1Rrp; IL18RA; IL18Ralpha2; IL1RRP | interleukin 18 receptor 1 |
| TCMBANKGE005372 | HIP1 | HIP-I; ILWEQ; SHON; SHONbeta; SHONgamma | huntingtin interacting protein 1 |
| TCMBANKGE011881 | NPM1 | B23; NPM | nucleophosmin 1 |
| TCMBANKGE004572 | KLF1 | EKLF; EKLF/KLF1 | Kruppel like factor 1 |
| TCMBANKGE014322 | IL23A | IL-23; IL-23A; IL23P19; P19; SGRF | interleukin 23 subunit alpha |
| TCMBANKGE010293 | SETBP1 | MRD29; SEB | SET binding protein 1 |
| TCMBANKGE000639 | HRAS | C-BAS/HAS; C-H-RAS; C-HA-RAS1; CTLO; H-RASIDX; HAMSV; HRAS1; RASH1; p21ras | HRas proto-oncogene, GTPase |
| TCMBANKGE004133 | KDM6A | KABUK2; UTX; bA386N14.2 | lysine demethylase 6A |
| TCMBANKGE000075 | IL1RN | DIRA; ICIL-1RA; IL-1RN; IL-1ra; IL-1ra3; IL1F3; IL1RA; IRAP; MVCD4 | interleukin 1 receptor antagonist |
| TCMBANKGE000315 | IL4 | BCGF-1; BCGF1; BSF-1; BSF1; IL-4 | interleukin 4 |
| TCMBANKGE000252 | PDE4A | DPDE2; PDE4; PDE46 | phosphodiesterase 4A |
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Dai SX Lab