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疾病ID:TCMBANKDI009402
疾病名:Intraepithelial Neoplasia
MeSH_Name:Neoplasms
HPO_Name:-
UMLS_Name:Neoplastic Process
DO_Name:-
疾病类型:disease
DisGeNET_Link:C0878500
MeSH_Link:C04
HPO_Link:-
UMLS_Link:T191
DO_Link:-
HERB_ID:-
疾病对应的植物
| ID | 拉丁名 | 药名 | 药用植物名 | 功能与主治 | 来源 | 药用部位 | 使用民族 |
|---|
疾病对应的化合物
| 化合物ID | 化合物名 | 别名 | 分子式 | 分子质量 | Smiles |
|---|
疾病对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE009156 | IGFBP5 | IBP5 | insulin like growth factor binding protein 5 |
| TCMBANKGE000117 | RUNX3 | AML2; CBFA3; PEBP2aC | RUNX family transcription factor 3 |
| TCMBANKGE003505 | FOXP1 | 12CC4; HSPC215; MFH; QRF1; hFKH1B | forkhead box P1 |
| TCMBANKGE000137 | PLAU | ATF; BDPLT5; QPD; UPA; URK; u-PA | plasminogen activator, urokinase |
| TCMBANKGE011973 | SLC39A6 | LIV-1; ZIP6 | solute carrier family 39 member 6 |
| TCMBANKGE000144 | POU5F1P3 | OCT3; OCT4; OCT4-pg3; OTF-3; OTF3; OTF3L; Oct-3; Oct-4; POU5F1; POU5F1L; POU5FLC12 | POU class 5 homeobox 1 pseudogene 3 |
| TCMBANKGE002101 | TGM3 | TGE; UHS2 | transglutaminase 3 |
| TCMBANKGE001002 | SYT1 | BAGOS; P65; SVP65; SYT | synaptotagmin 1 |
| TCMBANKGE003099 | CD163 | M130; MM130; SCARI1 | CD163 molecule |
| TCMBANKGE000567 | CDKN2A | ARF; CDK4I; CDKN2; CMM2; INK4; INK4A; MLM; MTS-1; MTS1; P14; P14ARF; P16; P16-INK4A; P16INK4; P16INK4A; P19; P19ARF; TP16 | cyclin dependent kinase inhibitor 2A |
| TCMBANKGE002211 | SPINK1 | PCTT; PSTI; Spink3; TATI; TCP | serine peptidase inhibitor Kazal type 1 |
| TCMBANKGE003358 | LGALS7 | GAL7; LGALS7A | galectin 7 |
| TCMBANKGE010781 | BRCA2 | BRCC2; BROVCA2; FACD; FAD; FAD1; FANCD; FANCD1; GLM3; PNCA2; XRCC11 | BRCA2 DNA repair associated |
| TCMBANKGE014106 | LPAR2 | EDG-4; EDG4; LPA-2; LPA2 | lysophosphatidic acid receptor 2 |
| TCMBANKGE004151 | PRL | GHA1 | prolactin |
| TCMBANKGE000173 | BRAF | B-RAF1; B-raf; BRAF1; NS7; RAFB1 | B-Raf proto-oncogene, serine/threonine kinase |
| TCMBANKGE013010 | COX2 | COII; MTCO2 | cytochrome c oxidase subunit II |
| TCMBANKGE000596 | PSMD9 | Rpn4; p27 | proteasome 26S subunit, non-ATPase 9 |
| TCMBANKGE003924 | CCND2 | KIAK0002; MPPH3 | cyclin D2 |
| TCMBANKGE001103 | MDM2 | ACTFS; HDMX; LSKB; hdm2 | MDM2 proto-oncogene |
| TCMBANKGE009975 | LAMC2 | B2T; BM600; CSF; EBR2; EBR2A; LAMB2T; LAMNB2 | laminin subunit gamma 2 |
| TCMBANKGE000871 | IGFBP3 | BP-53; IBP3 | insulin like growth factor binding protein 3 |
| TCMBANKGE003904 | VTN | V75; VN; VNT | vitronectin |
| TCMBANKGE013872 | HSPG2 | HSPG; PLC; PRCAN; SJA; SJS; SJS1 | heparan sulfate proteoglycan 2 |
| TCMBANKGE000047 | AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | AKT serine/threonine kinase 1 |
| TCMBANKGE010739 | TFF1 | BCEI; D21S21; HP1.A; HPS2; pNR-2; pS2 | trefoil factor 1 |
| TCMBANKGE000945 | HES1 | HES-1; HHL; HRY; bHLHb39 | hes family bHLH transcription factor 1 |
| TCMBANKGE000294 | CDKN1A | CAP20; CDKN1; CIP1; MDA-6; P21; SDI1; WAF1; p21CIP1 | cyclin dependent kinase inhibitor 1A |
| TCMBANKGE012553 | TNC | 150-225; DFNA56; GMEM; GP; HXB; JI; TN; TN-C | tenascin C |
| TCMBANKGE012461 | HPSE | HPA; HPA1; HPR1; HPSE1; HSE1 | heparanase |
| TCMBANKGE002613 | KRT19 | CK19; K19; K1CS | keratin 19 |
| TCMBANKGE000826 | SKP2 | FBL1; FBXL1; FLB1; p45 | S-phase kinase associated protein 2 |
| TCMBANKGE000674 | PDCD1 | CD279; PD-1; PD1; SLEB2; hPD-1; hPD-l; hSLE1 | programmed cell death 1 |
| TCMBANKGE000790 | DUSP4 | HVH2; MKP-2; MKP2; TYP | dual specificity phosphatase 4 |
| TCMBANKGE000201 | ESR1 | ER; ESR; ESRA; ESTRR; Era; NR3A1 | estrogen receptor 1 |
| TCMBANKGE000960 | STAT5A | MGF; STAT5 | signal transducer and activator of transcription 5A |
| TCMBANKGE000594 | ZNRD2 | SSSCA1; p27 | zinc ribbon domain containing 2 |
| TCMBANKGE011100 | BHLHA15 | BHLHB8; MIST1 | basic helix-loop-helix family member a15 |
| TCMBANKGE000477 | EZH2 | ENX-1; ENX1; EZH2b; KMT6; KMT6A; WVS; WVS2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| TCMBANKGE001184 | RELA | CMCU; NFKB3; p65 | RELA proto-oncogene, NF-kB subunit |
| TCMBANKGE000986 | ERBB2 | CD340; HER-2; HER-2/neu; HER2; MLN 19; NEU; NGL; TKR1 | erb-b2 receptor tyrosine kinase 2 |
| TCMBANKGE000323 | BRCA1 | BRCAI; BRCC1; BROVCA1; FANCS; IRIS; PNCA4; PPP1R53; PSCP; RNF53 | BRCA1 DNA repair associated |
| TCMBANKGE015054 | DUOX1 | LNOX1; NOXEF1; THOX1 | dual oxidase 1 |
| TCMBANKGE001257 | RET | CDHF12; CDHR16; HSCR1; MEN2A; MEN2B; MTC1; PTC; RET-ELE1 | ret proto-oncogene |
| TCMBANKGE000678 | EREG | EPR; ER; Ep | epiregulin |
| TCMBANKGE003580 | PDXP | CIN; PLP; dJ37E16.5 | pyridoxal phosphatase |
| TCMBANKGE000589 | CD68 | GP110; LAMP4; SCARD1 | CD68 molecule |
| TCMBANKGE010338 | FRAT1 | - | FRAT regulator of WNT signaling pathway 1 |
| TCMBANKGE004879 | WNK1 | HSAN2; HSN2; KDP; PPP1R167; PRKWNK1; PSK; p65 | WNK lysine deficient protein kinase 1 |
| TCMBANKGE011125 | ZIC1 | BAIDCS; CRS6; ZIC; ZNF201 | Zic family member 1 |
| TCMBANKGE001126 | NFE2L2 | HEBP1; IMDDHH; NRF2; Nrf-2 | nuclear factor, erythroid 2 like 2 |
| TCMBANKGE011947 | AQP1 | AQP-CHIP; CHIP28; CO | aquaporin 1 (Colton blood group) |
| TCMBANKGE004847 | EPHA1 | EPH; EPHT; EPHT1 | EPH receptor A1 |
| TCMBANKGE012464 | GLS | AAD20; CASGID; EIEE71; GAC; GAM; GDPAG; GLS1; KGA | glutaminase |
| TCMBANKGE002009 | PDHX | DLDBP; E3BP; OPDX; PDHXD; PDX1; proX | pyruvate dehydrogenase complex component X |
| TCMBANKGE000600 | IFI27 | FAM14D; ISG12; ISG12A; P27 | interferon alpha inducible protein 27 |
| TCMBANKGE000036 | SOCS1 | CIS1; CISH1; JAB; SOCS-1; SSI-1; SSI1; TIP-3; TIP3 | suppressor of cytokine signaling 1 |
| TCMBANKGE000793 | ALDH1A1 | ALDC; ALDH-E1; ALDH1; ALDH11; HEL-9; HEL-S-53e; HEL12; PUMB1; RALDH1 | aldehyde dehydrogenase 1 family member A1 |
| TCMBANKGE000877 | ABCG2 | ABC15; ABCP; BCRP; BCRP1; BMDP; CD338; CDw338; EST157481; GOUT1; MRX; MXR; MXR-1; MXR1; UAQTL1 | ATP binding cassette subfamily G member 2 (Junior blood group) |
| TCMBANKGE003499 | RASSF1 | 123F2; NORE2A; RASSF1A; RDA32; REH3P21 | Ras association domain family member 1 |
| TCMBANKGE003415 | GATA3 | HDR; HDRS | GATA binding protein 3 |
| TCMBANKGE000318 | HMGB1 | HMG-1; HMG1; HMG3; SBP-1 | high mobility group box 1 |
| TCMBANKGE002036 | CLDN18 | SFTA5; SFTPJ | claudin 18 |
| TCMBANKGE008107 | S100A1 | S100; S100-alpha; S100A | S100 calcium binding protein A1 |
| TCMBANKGE000597 | TMED7 | CGI-109; p24g3; p24gamma3; p27 | transmembrane p24 trafficking protein 7 |
| TCMBANKGE001073 | PTGS2 | COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 | prostaglandin-endoperoxide synthase 2 |
| TCMBANKGE009489 | ARHGEF28 | RGNEF; RIP2; p190RHOGEF | Rho guanine nucleotide exchange factor 28 |
| TCMBANKGE000587 | ITGAM | CD11B; CR3A; MAC-1; MAC1A; MO1A; SLEB6 | integrin subunit alpha M |
| TCMBANKGE010973 | EPCAM | DIAR5; EGP-2; EGP314; EGP40; ESA; HNPCC8; KS1/4; KSA; M4S1; MIC18; MK-1; TACSTD1; TROP1 | epithelial cell adhesion molecule |
| TCMBANKGE003381 | PDCD4 | H731 | programmed cell death 4 |
| TCMBANKGE001030 | NOTCH1 | AOS5; AOVD1; TAN1; hN1 | notch receptor 1 |
| TCMBANKGE000730 | HSPB2 | HSP27; Hs.78846; LOH11CR1K; MKBP | heat shock protein family B (small) member 2 |
| TCMBANKGE007368 | GSTP1 | DFN7; FAEES3; GST3; GSTP; HEL-S-22; PI | glutathione S-transferase pi 1 |
| TCMBANKGE011004 | FAM3C | GS3786; ILEI | FAM3 metabolism regulating signaling molecule C |
| TCMBANKGE000532 | PECAM1 | CD31; CD31/EndoCAM; GPIIA'; PECA1; PECAM-1; endoCAM | platelet and endothelial cell adhesion molecule 1 |
| TCMBANKGE012277 | MMP25 | MMP-25; MMP20; MMP20A; MMPL1; MT-MMP 6; MT-MMP6; MT6-MMP; MT6MMP; MTMMP6 | matrix metallopeptidase 25 |
| TCMBANKGE000227 | BMI1 | FLVI2/BMI1; PCGF4; RNF51; flvi-2/bmi-1 | BMI1 proto-oncogene, polycomb ring finger |
| TCMBANKGE000277 | CD33 | SIGLEC-3; SIGLEC3; p67 | CD33 molecule |
| TCMBANKGE002159 | PDPN | AGGRUS; GP36; GP40; Gp38; HT1A-1; OTS8; PA2.26; T1A; T1A-2; T1A2; TI1A | podoplanin |
| TCMBANKGE001088 | SMAD4 | DPC4; JIP; MADH4; MYHRS | SMAD family member 4 |
| TCMBANKGE000980 | SOX2 | ANOP3; MCOPS3 | SRY-box transcription factor 2 |
| TCMBANKGE006400 | PLG | - | plasminogen |
| TCMBANKGE000569 | CD34 | - | CD34 molecule |
| TCMBANKGE000652 | STAT5B | STAT5 | signal transducer and activator of transcription 5B |
| TCMBANKGE001697 | MMP1 | CLG; CLGN | matrix metallopeptidase 1 |
| TCMBANKGE007487 | VHL | HRCA1; RCA1; VHL1; pVHL | von Hippel-Lindau tumor suppressor |
| TCMBANKGE000301 | SLC2A1 | CSE; DYT17; DYT18; DYT9; EIG12; GLUT; GLUT-1; GLUT1; GLUT1DS; HTLVR; PED; SDCHCN | solute carrier family 2 member 1 |
| TCMBANKGE007910 | CENPH | - | centromere protein H |
| TCMBANKGE009809 | STIL | MCPH7; SIL | STIL centriolar assembly protein |
| TCMBANKGE012477 | MMP20 | AI2A2; MMP-20 | matrix metallopeptidase 20 |
| TCMBANKGE000935 | S100B | NEF; S100; S100-B; S100beta | S100 calcium binding protein B |
| TCMBANKGE000059 | NGFR | CD271; Gp80-LNGFR; TNFRSF16; p75(NTR); p75NTR | nerve growth factor receptor |
| TCMBANKGE000886 | SOX9 | CMD1; CMPD1; SRA1; SRXX2; SRXY10 | SRY-box transcription factor 9 |
| TCMBANKGE000525 | PDX1 | GSF; IDX-1; IPF1; IUF1; MODY4; PAGEN1; PDX-1; STF-1 | pancreatic and duodenal homeobox 1 |
| TCMBANKGE001879 | STS | ARSC; ARSC1; ASC; ES; SSDD; XLI | steroid sulfatase |
| TCMBANKGE009008 | F11R | CD321; JAM; JAM1; JAMA; JCAM; KAT; PAM-1 | F11 receptor |
| TCMBANKGE005423 | RIPK2 | CARD3; CARDIAK; CCK; GIG30; RICK; RIP2 | receptor interacting serine/threonine kinase 2 |
| TCMBANKGE001160 | CD274 | B7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1; hPD-L1 | CD274 molecule |
| TCMBANKGE007602 | MMP7 | MMP-7; MPSL1; PUMP-1 | matrix metallopeptidase 7 |
| TCMBANKGE003065 | NXT1 | MTR2; P15 | nuclear transport factor 2 like export factor 1 |
| TCMBANKGE000795 | POU5F1 | OCT3; OCT4; OTF-3; OTF3; OTF4; Oct-3; Oct-4 | POU class 5 homeobox 1 |
| TCMBANKGE012246 | TLR9 | CD289 | toll like receptor 9 |
| TCMBANKGE000445 | CD44 | CDW44; CSPG8; ECMR-III; HCELL; HUTCH-I; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1 | CD44 molecule (Indian blood group) |
| TCMBANKGE014820 | MUC6 | MUC-6 | mucin 6, oligomeric mucus/gel-forming |
| TCMBANKGE009945 | KDM6B | JMJD3; NEDCFSA | lysine demethylase 6B |
| TCMBANKGE001059 | LATS1 | WARTS; wts | large tumor suppressor kinase 1 |
| TCMBANKGE000522 | AGTR1 | AG2S; AGTR1B; AT1; AT1AR; AT1B; AT1BR; AT1R; AT2R1; HAT1R | angiotensin II receptor type 1 |
| TCMBANKGE008722 | APC | BTPS2; DESMD; DP2; DP2.5; DP3; GS; PPP1R46 | APC regulator of WNT signaling pathway |
| TCMBANKGE004968 | FGF8 | AIGF; FGF-8; HBGF-8; HH6; KAL6 | fibroblast growth factor 8 |
| TCMBANKGE009874 | CDKN2B | CDK4I; INK4B; MTS2; P15; TP15; p15INK4b | cyclin dependent kinase inhibitor 2B |
| TCMBANKGE013666 | PYCARD | ASC; CARD5; TMS; TMS-1; TMS1 | PYD and CARD domain containing |
| TCMBANKGE012981 | LDHB | HEL-S-281; LDH-B; LDH-H; LDHBD; TRG-5 | lactate dehydrogenase B |
| TCMBANKGE008990 | MCM7 | CDC47; MCM2; P1.1-MCM3; P1CDC47; P85MCM; PNAS146; PPP1R104 | minichromosome maintenance complex component 7 |
| TCMBANKGE005318 | S100A9 | 60B8AG; CAGB; CFAG; CGLB; L1AG; LIAG; MAC387; MIF; MRP14; NIF; P14 | S100 calcium binding protein A9 |
| TCMBANKGE011206 | CLDN7 | CEPTRL2; CLDN-7; CPETRL2; Hs.84359; claudin-1 | claudin 7 |
| TCMBANKGE000908 | MUC5AC | MUC5; TBM; leB; mucin | mucin 5AC, oligomeric mucus/gel-forming |
| TCMBANKGE001056 | KRAS | C-K-RAS; C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; K-Ras; K-Ras 2; KI-RAS; KRAS1; KRAS2; NS; NS3; OES; RALD; RASK2; c-Ki-ras; c-Ki-ras2 | KRAS proto-oncogene, GTPase |
| TCMBANKGE000884 | FN1 | CIG; ED-B; FINC; FN; FNZ; GFND; GFND2; LETS; MSF; SMDCF | fibronectin 1 |
| TCMBANKGE000885 | SPP1 | BNSP; BSPI; ETA-1; OPN | secreted phosphoprotein 1 |
| TCMBANKGE001125 | IGF1 | IGF; IGF-I; IGFI; MGF | insulin like growth factor 1 |
| TCMBANKGE007850 | CFL1 | CFL; HEL-S-15; cofilin | cofilin 1 |
| TCMBANKGE011953 | MEN1 | MEAI; SCG2 | menin 1 |
| TCMBANKGE013441 | SUB1 | P15; PC4; p14 | SUB1 regulator of transcription |
| TCMBANKGE008754 | H3P10 | p16 | H3 histone pseudogene 10 |
| TCMBANKGE004022 | MCM2 | BM28; CCNL1; CDCL1; D3S3194; DFNA70; MITOTIN; cdc19 | minichromosome maintenance complex component 2 |
| TCMBANKGE001096 | TLR4 | ARMD10; CD284; TLR-4; TOLL | toll like receptor 4 |
| TCMBANKGE000637 | SDHB | CWS2; IP; PGL4; SDH; SDH1; SDH2; SDHIP | succinate dehydrogenase complex iron sulfur subunit B |
| TCMBANKGE001045 | CCND1 | BCL1; D11S287E; PRAD1; U21B31 | cyclin D1 |
| TCMBANKGE001023 | CLDN1 | CLD1; ILVASC; SEMP1 | claudin 1 |
| TCMBANKGE012248 | PDLIM7 | LMP1; LMP3 | PDZ and LIM domain 7 |
| TCMBANKGE003588 | RRM2B | MTDPS8A; MTDPS8B; P53R2 | ribonucleotide reductase regulatory TP53 inducible subunit M2B |
| TCMBANKGE002668 | LMO4 | - | LIM domain only 4 |
| TCMBANKGE012113 | SLC7A5 | 4F2LC; CD98; D16S469E; E16; LAT1; MPE16 | solute carrier family 7 member 5 |
| TCMBANKGE006122 | GORASP1 | GOLPH5; GRASP65; P65 | golgi reassembly stacking protein 1 |
| TCMBANKGE000601 | DCTN6 | WS-3; WS3; p27 | dynactin subunit 6 |
| TCMBANKGE000468 | CTSB | APPS; CPSB; RECEUP | cathepsin B |
| TCMBANKGE001902 | ELF3 | EPR-1; ERT; ESE-1; ESX | E74 like ETS transcription factor 3 |
| TCMBANKGE006877 | MLH1 | COCA2; FCC2; HNPCC; HNPCC2; hMLH1 | mutL homolog 1 |
| TCMBANKGE000043 | BHLHE40 | BHLHB2; Clast5; DEC1; HLHB2; SHARP-2; SHARP2; STRA13; Stra14 | basic helix-loop-helix family member e40 |
| TCMBANKGE007886 | HLA-G | MHC-G | major histocompatibility complex, class I, G |
| TCMBANKGE002446 | AQP3 | AQP-3; GIL | aquaporin 3 (Gill blood group) |
| TCMBANKGE009273 | SLC1A5 | AAAT; ASCT2; ATBO; M7V1; M7VS1; R16; RDRC | solute carrier family 1 member 5 |
| TCMBANKGE000797 | HSPB1 | CMT2F; HEL-S-102; HMN2B; HS.76067; HSP27; HSP28; Hsp25; SRP27 | heat shock protein family B (small) member 1 |
| TCMBANKGE000236 | BDNF | ANON2; BULN2 | brain derived neurotrophic factor |
| TCMBANKGE005378 | KRT20 | CD20; CK-20; CK20; K20; KRT21 | keratin 20 |
| TCMBANKGE000295 | FOXO3 | AF6q21; FKHRL1; FKHRL1P2; FOXO2; FOXO3A | forkhead box O3 |
| TCMBANKGE000599 | H3P23 | p27 | H3 histone pseudogene 23 |
| TCMBANKGE001085 | MAPK8 | JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1c | mitogen-activated protein kinase 8 |
| TCMBANKGE007742 | HSPB3 | DHMN2C; HMN2C; HSPL27 | heat shock protein family B (small) member 3 |
| TCMBANKGE000143 | POU5F1P4 | OCT3; OCT4; OTF-3; OTF3; Oct-3; Oct-4; Oct4-pg4; POU5F1; POU5FLC1 | POU class 5 homeobox 1 pseudogene 4 |
| TCMBANKGE000703 | AREG | AR; AREGB; CRDGF; SDGF | amphiregulin |
| TCMBANKGE000650 | SUMO1 | DAP1; GMP1; OFC10; PIC1; SENP2; SMT3; SMT3C; SMT3H3; UBL1 | small ubiquitin like modifier 1 |
| TCMBANKGE000639 | HRAS | C-BAS/HAS; C-H-RAS; C-HA-RAS1; CTLO; H-RASIDX; HAMSV; HRAS1; RASH1; p21ras | HRas proto-oncogene, GTPase |
| TCMBANKGE009139 | TP73 | P73 | tumor protein p73 |
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