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疾病ID:TCMBANKDI009686
疾病名:Pituitary-dependent Cushing's disease
MeSH_Name:Nervous System Diseases; Endocrine System Diseases
HPO_Name:-
UMLS_Name:Disease or Syndrome
DO_Name:disease of anatomical entity; disease of cellular proliferation
疾病类型:disease
DisGeNET_Link:C0221406
MeSH_Link:C10; C19
HPO_Link:-
UMLS_Link:T047
DO_Link:DOID:7; DOID:14566
HERB_ID:-
疾病对应的植物
| ID | 拉丁名 | 药名 | 药用植物名 | 功能与主治 | 来源 | 药用部位 | 使用民族 |
|---|
疾病对应的化合物
| 化合物ID | 化合物名 | 别名 | 分子式 | 分子质量 | Smiles |
|---|
疾病对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE010770 | PCSK2 | NEC 2; NEC-2; NEC2; PC2; SPC2 | proprotein convertase subtilisin/kexin type 2 |
| TCMBANKGE001047 | E2F1 | E2F-1; RBAP1; RBBP3; RBP3 | E2F transcription factor 1 |
| TCMBANKGE000973 | EGF | HOMG4; URG | epidermal growth factor |
| TCMBANKGE000260 | APOB | FCHL2; FLDB; LDLCQ4; apoB-100; apoB-48 | apolipoprotein B |
| TCMBANKGE005856 | NEUROD1 | BETA2; BHF-1; MODY6; NEUROD; bHLHa3 | neuronal differentiation 1 |
| TCMBANKGE006975 | THBS1 | THBS; THBS-1; TSP; TSP-1; TSP1 | thrombospondin 1 |
| TCMBANKGE000831 | PRKACA | PKACA; PPNAD4 | protein kinase cAMP-activated catalytic subunit alpha |
| TCMBANKGE000567 | CDKN2A | ARF; CDK4I; CDKN2; CMM2; INK4; INK4A; MLM; MTS-1; MTS1; P14; P14ARF; P16; P16-INK4A; P16INK4; P16INK4A; P19; P19ARF; TP16 | cyclin dependent kinase inhibitor 2A |
| TCMBANKGE002381 | GIP | - | gastric inhibitory polypeptide |
| TCMBANKGE004151 | PRL | GHA1 | prolactin |
| TCMBANKGE000173 | BRAF | B-RAF1; B-raf; BRAF1; NS7; RAFB1 | B-Raf proto-oncogene, serine/threonine kinase |
| TCMBANKGE009622 | LIFR | CD118; LIF-R; SJS2; STWS; SWS | LIF receptor subunit alpha |
| TCMBANKGE006657 | MC2R | ACTHR | melanocortin 2 receptor |
| TCMBANKGE002237 | SLC20A1 | GLVR1; Glvr-1; PIT1; PiT-1 | solute carrier family 20 member 1 |
| TCMBANKGE013874 | GHSR | GHDP | growth hormone secretagogue receptor |
| TCMBANKGE014812 | SSTR2 | - | somatostatin receptor 2 |
| TCMBANKGE007882 | MED7 | ARC34; CRSP33; CRSP9 | mediator complex subunit 7 |
| TCMBANKGE008379 | FGFR4 | CD334; JTK2; TKF | fibroblast growth factor receptor 4 |
| TCMBANKGE002980 | CHEK2 | CDS1; CHK2; HuCds1; LFS2; PP1425; RAD53; hCds1 | checkpoint kinase 2 |
| TCMBANKGE000685 | ABL1 | ABL; BCR-ABL; CHDSKM; JTK7; bcr/abl; c-ABL; c-ABL1; p150; v-abl | ABL proto-oncogene 1, non-receptor tyrosine kinase |
| TCMBANKGE000060 | CRHR1 | CRF-R; CRF-R-1; CRF-R1; CRF1; CRFR-1; CRFR1; CRH-R-1; CRH-R1; CRHR; CRHR1L | corticotropin releasing hormone receptor 1 |
| TCMBANKGE000925 | PCNA | ATLD2 | proliferating cell nuclear antigen |
| TCMBANKGE008085 | CNTN3 | BIG-1; PANG; PCS | contactin 3 |
| TCMBANKGE001203 | MAPK1 | ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK | mitogen-activated protein kinase 1 |
| TCMBANKGE005231 | NR2C2 | TAK1; TR4 | nuclear receptor subfamily 2 group C member 2 |
| TCMBANKGE000882 | SERPINE1 | PAI; PAI-1; PAI1; PLANH1 | serpin family E member 1 |
| TCMBANKGE008495 | MOCOS | HMCS; MCS; MOS | molybdenum cofactor sulfurase |
| TCMBANKGE002281 | GNAI2 | GIP; GNAI2B; H_LUCA15.1; H_LUCA16.1 | G protein subunit alpha i2 |
| TCMBANKGE000168 | NR3C1 | GCCR; GCR; GCRST; GR; GRL | nuclear receptor subfamily 3 group C member 1 |
| TCMBANKGE006438 | PCSK1 | BMIQ12; NEC1; PC1; PC3; SPC3 | proprotein convertase subtilisin/kexin type 1 |
| TCMBANKGE000627 | BGLAP | BGP; OC; OCN | bone gamma-carboxyglutamate protein |
| TCMBANKGE001153 | EPHB2 | BDPLT22; CAPB; DRT; EK5; EPHT3; ERK; Hek5; PCBC; Tyro5 | EPH receptor B2 |
| TCMBANKGE006255 | SP1 | - | Sp1 transcription factor |
| TCMBANKGE000825 | CDKN1B | CDKN4; KIP1; MEN1B; MEN4; P27KIP1 | cyclin dependent kinase inhibitor 1B |
| TCMBANKGE005082 | APOA1 | HPALP2; apo(a) | apolipoprotein A1 |
| TCMBANKGE013679 | DICER1 | DCR1; Dicer; Dicer1e; GLOW; HERNA; K12H4.8-LIKE; MNG1; RMSE2 | dicer 1, ribonuclease III |
| TCMBANKGE002339 | GHR | GHBP; GHIP | growth hormone receptor |
| TCMBANKGE003313 | SSTR5 | SS-5-R | somatostatin receptor 5 |
| TCMBANKGE001178 | STAT3 | ADMIO; ADMIO1; APRF; HIES | signal transducer and activator of transcription 3 |
| TCMBANKGE001231 | CRHBP | CRF-BP; CRFBP | corticotropin releasing hormone binding protein |
| TCMBANKGE000523 | BMP4 | BMP2B; BMP2B1; MCOPS6; OFC11; ZYME | bone morphogenetic protein 4 |
| TCMBANKGE000280 | VIM | - | vimentin |
| TCMBANKGE011129 | GH1 | GH; GH-N; GHB5; GHN; IGHD1A; IGHD1B; IGHD2; hGH-N | growth hormone 1 |
| TCMBANKGE000728 | MGMT | - | O-6-methylguanine-DNA methyltransferase |
| TCMBANKGE010750 | SFRP2 | FRP-2; SARP1; SDF-5 | secreted frizzled related protein 2 |
| TCMBANKGE009806 | PRSS55 | CT153; T-SP1; TSP1; UNQ9391 | serine protease 55 |
| TCMBANKGE002052 | CIB1 | CIB; CIBP; KIP1; PRKDCIP; SIP2-28 | calcium and integrin binding 1 |
| TCMBANKGE001141 | PPARA | NR1C1; PPAR; PPARalpha; hPPAR | peroxisome proliferator activated receptor alpha |
| TCMBANKGE014912 | SCG5 | 7B2; P7B2; SGNE1; SgV | secretogranin V |
| TCMBANKGE012032 | SERPINA6 | CBG | serpin family A member 6 |
| TCMBANKGE002445 | GHRL | MTLRP | ghrelin and obestatin prepropeptide |
| TCMBANKGE001051 | MAP2K7 | JNKK2; MAPKK7; MEK; MEK 7; MKK7; PRKMK7; SAPKK-4; SAPKK4 | mitogen-activated protein kinase kinase 7 |
| TCMBANKGE009836 | AVPR1B | AVPR3; V1bR | arginine vasopressin receptor 1B |
| TCMBANKGE002899 | PAX7 | HUP1; MYOSCO; PAX7B; RMS2 | paired box 7 |
| TCMBANKGE014962 | COX8A | COX; COX8; COX8-2; COX8L; VIII; VIII-L | cytochrome c oxidase subunit 8A |
| TCMBANKGE007509 | KRT5 | CK5; DDD; DDD1; EBS2; K5; KRT5A | keratin 5 |
| TCMBANKGE000758 | HSF1 | HSTF1 | heat shock transcription factor 1 |
| TCMBANKGE000750 | NR4A1 | GFRP1; HMR; N10; NAK-1; NGFIB; NP10; NUR77; TR3 | nuclear receptor subfamily 4 group A member 1 |
| TCMBANKGE000471 | POMC | ACTH; CLIP; LPH; MSH; NPP; OBAIRH; POC | proopiomelanocortin |
| TCMBANKGE002555 | HSD11B1 | 11-DH; 11-beta-HSD1; CORTRD2; HDL; HSD11; HSD11B; HSD11L; SDR26C1 | hydroxysteroid 11-beta dehydrogenase 1 |
| TCMBANKGE001160 | CD274 | B7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1; hPD-L1 | CD274 molecule |
| TCMBANKGE008240 | MSH2 | COCA1; FCC1; HNPCC; HNPCC1; LCFS2; hMSH2 | mutS homolog 2 |
| TCMBANKGE009400 | GNAS | AHO; C20orf45; GNAS1; GPSA; GSA; GSP; NESP; PITA3; POH; SCG6; SgVI | GNAS complex locus |
| TCMBANKGE002321 | SSTR1 | SRIF-2; SS-1-R; SS1-R; SS1R | somatostatin receptor 1 |
| TCMBANKGE011235 | SLC8A1 | NCX1 | solute carrier family 8 member A1 |
| TCMBANKGE001144 | CD14 | - | CD14 molecule |
| TCMBANKGE012915 | TBX19 | TBS19; TPIT; dJ747L4.1 | T-box transcription factor 19 |
| TCMBANKGE014262 | CYP11B1 | CPN1; CYP11B; FHI; P450C11 | cytochrome P450 family 11 subfamily B member 1 |
| TCMBANKGE000661 | HDAC2 | HD2; KDAC2; RPD3; YAF1 | histone deacetylase 2 |
| TCMBANKGE012586 | LPXN | LDPL | leupaxin |
| TCMBANKGE001185 | PPARG | CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma | peroxisome proliferator activated receptor gamma |
| TCMBANKGE013295 | USP8 | HumORF8; PITA4; SPG59; UBPY | ubiquitin specific peptidase 8 |
| TCMBANKGE001125 | IGF1 | IGF; IGF-I; IGFI; MGF | insulin like growth factor 1 |
| TCMBANKGE000419 | SMS | MRSR; SPMSY; SRS; SpS | spermine synthase |
| TCMBANKGE013405 | SPZ1 | CILD38; NYD-TSP1; PPP1R148 | spermatogenic leucine zipper 1 |
| TCMBANKGE013388 | CABLES1 | CABL1; CABLES; HsT2563; IK3-1 | Cdk5 and Abl enzyme substrate 1 |
| TCMBANKGE011953 | MEN1 | MEAI; SCG2 | menin 1 |
| TCMBANKGE008754 | H3P10 | p16 | H3 histone pseudogene 10 |
| TCMBANKGE004079 | NDUFA2 | B8; CD14; CIB8; MC1DN13 | NADH:ubiquinone oxidoreductase subunit A2 |
| TCMBANKGE001045 | CCND1 | BCL1; D11S287E; PRAD1; U21B31 | cyclin D1 |
| TCMBANKGE011872 | CDH23 | CDHR23; PITA5; USH1D | cadherin related 23 |
| TCMBANKGE007547 | BRD2 | BRD2-IT1; D6S113E; FSH; FSRG1; NAT; O27.1.1; RING3; RNF3 | bromodomain containing 2 |
| TCMBANKGE014473 | CRH | CRF; CRH1 | corticotropin releasing hormone |
| TCMBANKGE001172 | HSP90AA1 | EL52; HEL-S-65p; HSP86; HSP89A; HSP90A; HSP90N; HSPC1; HSPCA; HSPCAL1; HSPCAL4; HSPN; Hsp103; Hsp89; Hsp90; LAP-2; LAP2 | heat shock protein 90 alpha family class A member 1 |
| TCMBANKGE000555 | SST | SMST | somatostatin |
| TCMBANKGE000869 | DRD2 | D2DR; D2R | dopamine receptor D2 |
| TCMBANKGE004230 | CIRBP | CIRP | cold inducible RNA binding protein |
| TCMBANKGE006516 | AIP | ARA9; FKBP16; FKBP37; PITA1; SMTPHN; XAP-2; XAP2 | aryl hydrocarbon receptor interacting protein |
| TCMBANKGE012224 | VDR | NR1I1; PPP1R163 | vitamin D receptor |
| TCMBANKGE006866 | HSD11B2 | AME; AME1; HSD11K; HSD2; SDR9C3 | hydroxysteroid 11-beta dehydrogenase 2 |
| TCMBANKGE000459 | PRKAR1A | ACRDYS1; ADOHR; CAR; CNC; CNC1; PKR1; PPNAD1; PRKAR1; TSE1 | protein kinase cAMP-dependent type I regulatory subunit alpha |
| TCMBANKGE012329 | AGRP | AGRT; ART; ASIP2 | agouti related neuropeptide |
| TCMBANKGE009580 | SERPINB2 | HsT1201; PAI; PAI-2; PAI2; PLANH2 | serpin family B member 2 |
| TCMBANKGE000992 | KLK3 | APS; KLK2A1; PSA; hK3 | kallikrein related peptidase 3 |
| TCMBANKGE009139 | TP73 | P73 | tumor protein p73 |
滇IICP备16009434号-1 |
Dai SX Lab