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疾病ID:TCMBANKDI010589
疾病名:Ichthyoses
MeSH_Name:Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
HPO_Name:Abnormality of the integument
UMLS_Name:Disease or Syndrome
DO_Name:disease of anatomical entity
疾病类型:disease
DisGeNET_Link:C0020757
MeSH_Link:C16; C17
HPO_Link:HP:0001574
UMLS_Link:T047
DO_Link:DOID:7
HERB_ID:-
疾病对应的植物
| ID | 拉丁名 | 药名 | 药用植物名 | 功能与主治 | 来源 | 药用部位 | 使用民族 |
|---|
疾病对应的化合物
| 化合物ID | 化合物名 | 别名 | 分子式 | 分子质量 | Smiles |
|---|
疾病对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE011020 | FHL1 | FCMSU; FHL-1; FHL1A; FHL1B; FLH1A; KYOT; RBMX1A; RBMX1B; SLIM; SLIM-1; SLIM1; SLIMMER; XMPMA | four and a half LIM domains 1 |
| TCMBANKGE013731 | KRT2 | CK-2e; K2e; KRT2A; KRT2E; KRTE | keratin 2 |
| TCMBANKGE008755 | RNF113A | Cwc24; RNF113; TTD5; ZNF183 | ring finger protein 113A |
| TCMBANKGE001033 | FGFR1 | BFGFR; CD331; CEK; ECCL; FGFBR; FGFR-1; FLG; FLT-2; FLT2; HBGFR; HH2; HRTFDS; KAL2; N-SAM; OGD; bFGF-R-1 | fibroblast growth factor receptor 1 |
| TCMBANKGE006194 | ITGB6 | AI1H | integrin subunit beta 6 |
| TCMBANKGE011715 | PEX3 | PBD10A; PBD10B; TRG18 | peroxisomal biogenesis factor 3 |
| TCMBANKGE014592 | ALDH3A2 | ALDH10; FALDH; SLS | aldehyde dehydrogenase 3 family member A2 |
| TCMBANKGE009204 | MBTPS2 | BRESEK; IFAP; KFSD; KFSDX; OI19; OLMSX; S2P | membrane bound transcription factor peptidase, site 2 |
| TCMBANKGE009926 | AP1S1 | AP19; CLAPS1; EKV3; MEDNIK; SIGMA1A | adaptor related protein complex 1 subunit sigma 1 |
| TCMBANKGE000775 | MAP2K2 | CFC4; MAPKK2; MEK2; MKK2; PRKMK2 | mitogen-activated protein kinase kinase 2 |
| TCMBANKGE011040 | TACR3 | HH11; NK-3R; NK3; NK3R; NKR; TAC3R; TAC3RL | tachykinin receptor 3 |
| TCMBANKGE003153 | DMD | BMD; CMD3B; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; MRX85 | dystrophin |
| TCMBANKGE009362 | ASPRV1 | MUNO; SASP; SASPase; Taps | aspartic peptidase retroviral like 1 |
| TCMBANKGE000173 | BRAF | B-RAF1; B-raf; BRAF1; NS7; RAFB1 | B-Raf proto-oncogene, serine/threonine kinase |
| TCMBANKGE013010 | COX2 | COII; MTCO2 | cytochrome c oxidase subunit II |
| TCMBANKGE000313 | JUN | AP-1; AP1; c-Jun; cJUN; p39 | Jun proto-oncogene, AP-1 transcription factor subunit |
| TCMBANKGE006661 | PNPLA6 | BNHS; LNMS; NTE; NTEMND; OMCS; SPG39; iPLA2delta; sws | patatin like phospholipase domain containing 6 |
| TCMBANKGE001103 | MDM2 | ACTFS; HDMX; LSKB; hdm2 | MDM2 proto-oncogene |
| TCMBANKGE005209 | PHGDH | 3-PGDH; 3PGDH; HEL-S-113; NLS; NLS1; PDG; PGAD; PGD; PGDH; PHGDHD; SERA | phosphoglycerate dehydrogenase |
| TCMBANKGE003985 | DCC | CRC18; CRCR1; HGPPS2; IGDCC1; MRMV1; NTN1R1 | DCC netrin 1 receptor |
| TCMBANKGE001052 | NLRP3 | AGTAVPRL; AII; AVP; C1orf7; CIAS1; CLR1.1; DFNA34; FCAS; FCAS1; FCU; KEFH; MWS; NALP3; PYPAF1 | NLR family pyrin domain containing 3 |
| TCMBANKGE005585 | PEX6 | HMLR2; PAF-2; PAF2; PBD4A; PDB4B; PXAAA1 | peroxisomal biogenesis factor 6 |
| TCMBANKGE009316 | KRT6B | CK-6B; CK6B; K6B; KRTL1; PC2; PC4 | keratin 6B |
| TCMBANKGE008946 | BLM | BS; MGRISCE1; RECQ2; RECQL2; RECQL3 | BLM RecQ like helicase |
| TCMBANKGE014170 | PNPLA1 | ARCI10; dJ50J22.1 | patatin like phospholipase domain containing 1 |
| TCMBANKGE013293 | ELOVL4 | ADMD; CT118; ISQMR; SCA34; STGD2; STGD3 | ELOVL fatty acid elongase 4 |
| TCMBANKGE011178 | COL4A5 | ASLN; ATS; ATS1; CA54 | collagen type IV alpha 5 chain |
| TCMBANKGE014411 | CST6 | ECTD15 | cystatin E/M |
| TCMBANKGE014338 | IL2RB | CD122; IL15RB; IMD63; P70-75 | interleukin 2 receptor subunit beta |
| TCMBANKGE000720 | KRT1 | CK1; EHK; EHK1; EPPK; K1; KRT1A; NEPPK | keratin 1 |
| TCMBANKGE002738 | MPLKIP | ABHS; C7orf11; ORF20; TTD4 | M-phase specific PLK1 interacting protein |
| TCMBANKGE004021 | FMR1 | FMRP; FRAXA; POF; POF1 | FMRP translational regulator 1 |
| TCMBANKGE000441 | ERCC3 | BTF2; GTF2H; RAD25; TFIIH; TTD2; XPB | ERCC excision repair 3, TFIIH core complex helicase subunit |
| TCMBANKGE014979 | NOD2 | ACUG; BLAU; BLAUS; CARD15; CD; CLR16.3; IBD1; NLRC2; NOD2B; PSORAS1; YAOS | nucleotide binding oligomerization domain containing 2 |
| TCMBANKGE009638 | AMY2B | AMY2; AMY3; HXA | amylase alpha 2B |
| TCMBANKGE009239 | SRD5A3 | CDG1P; CDG1Q; KRIZI; SRD5A2L; SRD5A2L1 | steroid 5 alpha-reductase 3 |
| TCMBANKGE012356 | TGM5 | PSS2; TGASE5; TGASEX; TGM6; TGMX; TGX | transglutaminase 5 |
| TCMBANKGE000692 | PNPLA2 | 1110001C14Rik; ATGL; FP17548; PEDF-R; TTS-2.2; TTS2; iPLA2zeta | patatin like phospholipase domain containing 2 |
| TCMBANKGE013379 | PIGL | CHIME | phosphatidylinositol glycan anchor biosynthesis class L |
| TCMBANKGE006910 | ELOVL3 | CIG-30; CIG30 | ELOVL fatty acid elongase 3 |
| TCMBANKGE008036 | PHYH | LN1; LNAP1; PAHX; PHYH1; RD | phytanoyl-CoA 2-hydroxylase |
| TCMBANKGE008559 | GJB2 | BAPS; CX26; DFNA3; DFNA3A; DFNB1; DFNB1A; HID; KID; NSRD1; PPK | gap junction protein beta 2 |
| TCMBANKGE007169 | VCX3A | VCX-8r; VCX-A; VCX3; VCX8R; VCXA | variable charge X-linked 3A |
| TCMBANKGE007341 | KIF22 | A-328A3.2; KID; KNSL4; OBP; OBP-1; OBP-2; SEMDJL2 | kinesin family member 22 |
| TCMBANKGE010327 | EMD | EDMD; LEMD5; STA | emerin |
| TCMBANKGE001278 | CERS3 | ARCI9; LASS3 | ceramide synthase 3 |
| TCMBANKGE003798 | PSAT1 | EPIP; NLS2; PSA; PSAT; PSATD | phosphoserine aminotransferase 1 |
| TCMBANKGE009773 | PROK2 | BV8; HH4; KAL4; MIT1; PK2 | prokineticin 2 |
| TCMBANKGE000243 | LMNA | CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; LMNL1; MADA; PRO1 | lamin A/C |
| TCMBANKGE008796 | HSD17B6 | HSE; RODH; SDR9C6 | hydroxysteroid 17-beta dehydrogenase 6 |
| TCMBANKGE005922 | LPIN2 | - | lipin 2 |
| TCMBANKGE015025 | CHKB | CHETK; CHKL; CK; CKB; CKEKB; EK; EKB; MDCMC | choline kinase beta |
| TCMBANKGE009416 | GTF2E2 | FE; TF2E2; TFIIE-B; TTD6 | general transcription factor IIE subunit 2 |
| TCMBANKGE000231 | MAP2K1 | CFC3; MAPKK1; MEK1; MKK1; PRKMK1 | mitogen-activated protein kinase kinase 1 |
| TCMBANKGE006347 | AP1B1 | ADTB1; AP105A; BAM22; CLAPB2; KIDAR | adaptor related protein complex 1 subunit beta 1 |
| TCMBANKGE011325 | CYP4F22 | ARCI5; INLNE; LI3 | cytochrome P450 family 4 subfamily F member 22 |
| TCMBANKGE001091 | ND5 | MTND5 | NADH dehydrogenase, subunit 5 (complex I) |
| TCMBANKGE009405 | KRT6A | CK-6C; CK-6E; CK6A; CK6C; CK6D; K6A; K6C; K6D; KRT6C; KRT6D; PC3 | keratin 6A |
| TCMBANKGE003415 | GATA3 | HDR; HDRS | GATA binding protein 3 |
| TCMBANKGE007385 | NRAS | ALPS4; CMNS; N-ras; NCMS; NRAS1; NS6 | NRAS proto-oncogene, GTPase |
| TCMBANKGE008263 | FEZF1 | FEZ; HH22; ZNF312B | FEZ family zinc finger 1 |
| TCMBANKGE014847 | PUDP | DXF68S1E; FAM16AX; GS1; HDHD1; HDHD1A | pseudouridine 5'-phosphatase |
| TCMBANKGE011937 | LIPN | ARCI8; LI4; LIPL4; bA186O14.3 | lipase family member N |
| TCMBANKGE005577 | SEMA3A | COLL1; HH16; Hsema-I; Hsema-III; SEMA1; SEMAD; SEMAIII; SEMAL; SemD; coll-1 | semaphorin 3A |
| TCMBANKGE012740 | FGF17 | FGF-13; FGF-17; HH20 | fibroblast growth factor 17 |
| TCMBANKGE000730 | HSPB2 | HSP27; Hs.78846; LOH11CR1K; MKBP | heat shock protein family B (small) member 2 |
| TCMBANKGE003990 | GTF2H5 | C6orf175; TFB5; TFIIH; TGF2H5; TTD; TTD-A; TTD3; TTDA; bA120J8.2 | general transcription factor IIH subunit 5 |
| TCMBANKGE007939 | PEX2 | PAF1; PBD5A; PBD5B; PMP3; PMP35; PXMP3; RNF72; ZWS3 | peroxisomal biogenesis factor 2 |
| TCMBANKGE010462 | ALOX12B | 12R-LOX; ARCI2 | arachidonate 12-lipoxygenase, 12R type |
| TCMBANKGE001947 | PEX13 | NALD; PBD11A; PBD11B; ZWS | peroxisomal biogenesis factor 13 |
| TCMBANKGE003866 | ABCA12 | ARCI4A; ARCI4B; ICR2B; LI2 | ATP binding cassette subfamily A member 12 |
| TCMBANKGE004855 | PEX16 | PBD8A; PBD8B | peroxisomal biogenesis factor 16 |
| TCMBANKGE005617 | SNAP29 | CEDNIK; SNAP-29 | synaptosome associated protein 29 |
| TCMBANKGE012336 | DOLK | CDG1M; DK; DK1; SEC59; TMEM15 | dolichol kinase |
| TCMBANKGE012625 | BGN | DSPG1; MRLS; PG-S1; PGI; SEMDX; SLRR1A | biglycan |
| TCMBANKGE000510 | KRT17 | 39.1; CK-17; K17; PC; PC2; PCHC1 | keratin 17 |
| TCMBANKGE002136 | GBA | GBA1; GCB; GLUC | glucosylceramidase beta |
| TCMBANKGE002475 | SDR9C7 | ARCI13; RDHS; SDR-O; SDRO | short chain dehydrogenase/reductase family 9C member 7 |
| TCMBANKGE000950 | SULT2A1 | DHEA-ST; DHEAS; HST; ST2; ST2A1; ST2A3; STD; hSTa | sulfotransferase family 2A member 1 |
| TCMBANKGE001879 | STS | ARSC; ARSC1; ASC; ES; SSDD; XLI | steroid sulfatase |
| TCMBANKGE009074 | EBP | CDPX2; CHO2; CPX; CPXD; MEND | EBP cholestenol delta-isomerase |
| TCMBANKGE013488 | SYNE1 | 8B; AMCM; ARCA1; C6orf98; CPG2; EDMD4; KASH1; MYNE1; Nesp1; SCAR8; dJ45H2.2 | spectrin repeat containing nuclear envelope protein 1 |
| TCMBANKGE004127 | CSTA | AREI; PSS4; STF1; STFA | cystatin A |
| TCMBANKGE000941 | TXNRD1 | GRIM-12; TR; TR1; TRXR1; TXNR | thioredoxin reductase 1 |
| TCMBANKGE009261 | SLC27A4 | ACSVL4; FATP4; IPS | solute carrier family 27 member 4 |
| TCMBANKGE002584 | CHD7 | CRG; HH5; IS3; KAL5 | chromodomain helicase DNA binding protein 7 |
| TCMBANKGE004968 | FGF8 | AIGF; FGF-8; HBGF-8; HH6; KAL6 | fibroblast growth factor 8 |
| TCMBANKGE004143 | KISS1R | AXOR12; CPPB1; GPR54; HH8; HOT7T175; KISS-1R | KISS1 receptor |
| TCMBANKGE008826 | LBR | C14SR; DHCR14B; LMN2R; PHA; PHASK; TDRD18 | lamin B receptor |
| TCMBANKGE013113 | NLGN4X | ASPGX2; AUTSX2; HLNX; HNL4X; NLGN4 | neuroligin 4 X-linked |
| TCMBANKGE014504 | ST14 | ARCI11; HAI; MT-SP1; MTSP1; PRSS14; SNC19; TADG15; TMPRSS14 | ST14 transmembrane serine protease matriptase |
| TCMBANKGE000366 | DUSP6 | HH19; MKP3; PYST1 | dual specificity phosphatase 6 |
| TCMBANKGE009234 | COL7A1 | EBD1; EBDCT; EBR1; NDNC8 | collagen type VII alpha 1 chain |
| TCMBANKGE000361 | ERCC2 | COFS2; EM9; TFIIH; TTD; TTD1; XPD | ERCC excision repair 2, TFIIH core complex helicase subunit |
| TCMBANKGE012988 | PEX1 | HMLR1; PBD1A; PBD1B; ZWS; ZWS1 | peroxisomal biogenesis factor 1 |
| TCMBANKGE005639 | PEX5 | PBD2A; PBD2B; PTS1-BP; PTS1R; PXR1; RCDP5 | peroxisomal biogenesis factor 5 |
| TCMBANKGE005632 | PEX14 | NAPP2; PBD13A; Pex14p; dJ734G22.2 | peroxisomal biogenesis factor 14 |
| TCMBANKGE011206 | CLDN7 | CEPTRL2; CLDN-7; CPETRL2; Hs.84359; claudin-1 | claudin 7 |
| TCMBANKGE007252 | IL22 | IL-21; IL-22; IL-D110; IL-TIF; ILTIF; TIFIL-23; TIFa; zcyto18 | interleukin 22 |
| TCMBANKGE001056 | KRAS | C-K-RAS; C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; K-Ras; K-Ras 2; KI-RAS; KRAS1; KRAS2; NS; NS3; OES; RALD; RASK2; c-Ki-ras; c-Ki-ras2 | KRAS proto-oncogene, GTPase |
| TCMBANKGE000240 | IL17A | CTLA-8; CTLA8; IL-17; IL-17A; IL17 | interleukin 17A |
| TCMBANKGE014368 | HESX1 | ANF; CPHD5; RPX | HESX homeobox 1 |
| TCMBANKGE010036 | AHSG | A2HS; AHS; APMR1; FETUA; HSGA | alpha 2-HS glycoprotein |
| TCMBANKGE000586 | IL17F | CANDF6; IL-17F; ML-1; ML1 | interleukin 17F |
| TCMBANKGE003673 | SLC27A1 | ACSVL5; FATP; FATP-1; FATP1 | solute carrier family 27 member 1 |
| TCMBANKGE012076 | SPRY4 | HH17 | sprouty RTK signaling antagonist 4 |
| TCMBANKGE002936 | GAL | ETL8; GAL-GMAP; GALN; GLNN; GMAP | galanin and GMAP prepropeptide |
| TCMBANKGE002727 | ALOXE3 | ARCI3; E-LOX; eLOX-3; eLOX3 | arachidonate lipoxygenase 3 |
| TCMBANKGE004675 | CARD14 | BIMP2; CARMA2; PRP; PSORS2; PSS1 | caspase recruitment domain family member 14 |
| TCMBANKGE012270 | SYNE2 | EDMD5; KASH2; NUA; NUANCE; Nesp2; Nesprin-2; SYNE-2; TROPH | spectrin repeat containing nuclear envelope protein 2 |
| TCMBANKGE013777 | SLURP1 | ANUP; ARS; ArsB; LY6-MT; LY6LS; MDM | secreted LY6/PLAUR domain containing 1 |
| TCMBANKGE007478 | MX1 | IFI-78K; IFI78; MX; MxA; lncMX1-215 | MX dynamin like GTPase 1 |
| TCMBANKGE004601 | DMKN | UNQ729; ZD52F10 | dermokine |
| TCMBANKGE009780 | SULT2B1 | ARCI14; HSST2 | sulfotransferase family 2B member 1 |
| TCMBANKGE001023 | CLDN1 | CLD1; ILVASC; SEMP1 | claudin 1 |
| TCMBANKGE007024 | SLC29A3 | ENT3; HCLAP; HJCD; PHID | solute carrier family 29 member 3 |
| TCMBANKGE004377 | GINS1 | IMD55; PSF1 | GINS complex subunit 1 |
| TCMBANKGE001620 | TMPRSS6 | IRIDA; MT2 | transmembrane serine protease 6 |
| TCMBANKGE006425 | SLC26A4 | DFNB4; EVA; PDS; TDH2B | solute carrier family 26 member 4 |
| TCMBANKGE003455 | ABCA3 | ABC-C; ABC3; EST111653; LBM180; SMDP3 | ATP binding cassette subfamily A member 3 |
| TCMBANKGE008873 | SBDS | CGI-97; SDS; SWDS | SBDS ribosome maturation factor |
| TCMBANKGE010907 | PROKR2 | GPR73L1; GPR73b; GPRg2; HH3; KAL3; PKR2; dJ680N4.3 | prokineticin receptor 2 |
| TCMBANKGE012504 | STIM1 | D11S4896E; GOK; IMD10; STRMK; TAM; TAM1 | stromal interaction molecule 1 |
| TCMBANKGE012046 | ARSA | ASA; MLD | arylsulfatase A |
| TCMBANKGE011864 | TGM1 | ARCI1; ICR2; KTG; LI; LI1; TGASE; TGK | transglutaminase 1 |
| TCMBANKGE002395 | HLA-DOA | HLA-DNA; HLA-DZA; HLADZ | major histocompatibility complex, class II, DO alpha |
| TCMBANKGE000797 | HSPB1 | CMT2F; HEL-S-102; HMN2B; HS.76067; HSP27; HSP28; Hsp25; SRP27 | heat shock protein family B (small) member 1 |
| TCMBANKGE008313 | SRP54 | SCN8 | signal recognition particle 54 |
| TCMBANKGE007742 | HSPB3 | DHMN2C; HMN2C; HSPL27 | heat shock protein family B (small) member 3 |
| TCMBANKGE001318 | AQP6 | AQP2L; KID | aquaporin 6 |
| TCMBANKGE014322 | IL23A | IL-23; IL-23A; IL23P19; P19; SGRF | interleukin 23 subunit alpha |
| TCMBANKGE001306 | MSMO1 | DESP4; ERG25; MCCPD; SC4MOL | methylsterol monooxygenase 1 |
| TCMBANKGE005655 | FLG | ATOD2 | filaggrin |
| TCMBANKGE000722 | KRT10 | BCIE; BIE; CK10; EHK; K10; KPP | keratin 10 |
| TCMBANKGE000639 | HRAS | C-BAS/HAS; C-H-RAS; C-HA-RAS1; CTLO; H-RASIDX; HAMSV; HRAS1; RASH1; p21ras | HRas proto-oncogene, GTPase |
| TCMBANKGE010852 | DGAT1 | ARAT; ARGP1; DGAT; DIAR7 | diacylglycerol O-acyltransferase 1 |
| TCMBANKGE012516 | DSP | DCWHKTA; DP | desmoplakin |
| TCMBANKGE014591 | SGPL1 | NPHS14; S1PL; SPL | sphingosine-1-phosphate lyase 1 |
| TCMBANKGE013921 | MPDU1 | CDGIF; HBEBP2BPA; Lec35; My008; PP3958; PQLC5; SL15; SLC66A5 | mannose-P-dolichol utilization defect 1 |
| TCMBANKGE010425 | FLRT3 | HH21 | fibronectin leucine rich transmembrane protein 3 |
| TCMBANKGE005064 | ABHD5 | CGI58; IECN2; NCIE2 | abhydrolase domain containing 5, lysophosphatidic acid acyltransferase |
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