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疾病ID:TCMBANKDI011305
疾病名:Turcot syndrome (disorder)
MeSH_Name:Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms; Nervous System Diseases
HPO_Name:-
UMLS_Name:Disease or Syndrome
DO_Name:-
疾病类型:disease
DisGeNET_Link:C0265325
MeSH_Link:C16; C06; C04; C10
HPO_Link:-
UMLS_Link:T047
DO_Link:-
HERB_ID:-
疾病对应的植物
| ID | 拉丁名 | 药名 | 药用植物名 | 功能与主治 | 来源 | 药用部位 | 使用民族 |
|---|
疾病对应的化合物
| 化合物ID | 化合物名 | 别名 | 分子式 | 分子质量 | Smiles |
|---|
疾病对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE000573 | CDX2 | CDX-3; CDX2/AS; CDX3 | caudal type homeobox 2 |
| TCMBANKGE000607 | CD80 | B7; B7-1; B7.1; BB1; CD28LG; CD28LG1; LAB7 | CD80 molecule |
| TCMBANKGE011709 | MAP3K11 | MEKK11; MLK-3; MLK3; PTK1; SPRK | mitogen-activated protein kinase kinase kinase 11 |
| TCMBANKGE001132 | BAX | BCL2L4 | BCL2 associated X, apoptosis regulator |
| TCMBANKGE000567 | CDKN2A | ARF; CDK4I; CDKN2; CMM2; INK4; INK4A; MLM; MTS-1; MTS1; P14; P14ARF; P16; P16-INK4A; P16INK4; P16INK4A; P19; P19ARF; TP16 | cyclin dependent kinase inhibitor 2A |
| TCMBANKGE010781 | BRCA2 | BRCC2; BROVCA2; FACD; FAD; FAD1; FANCD; FANCD1; GLM3; PNCA2; XRCC11 | BRCA2 DNA repair associated |
| TCMBANKGE000173 | BRAF | B-RAF1; B-raf; BRAF1; NS7; RAFB1 | B-Raf proto-oncogene, serine/threonine kinase |
| TCMBANKGE008660 | ALCAM | CD166; MEMD | activated leukocyte cell adhesion molecule |
| TCMBANKGE002980 | CHEK2 | CDS1; CHK2; HuCds1; LFS2; PP1425; RAD53; hCds1 | checkpoint kinase 2 |
| TCMBANKGE000937 | PAX5 | ALL3; BSAP | paired box 5 |
| TCMBANKGE001156 | CASP3 | CPP32; CPP32B; SCA-1 | caspase 3 |
| TCMBANKGE014240 | NF2 | ACN; BANF; SCH | neurofibromin 2 |
| TCMBANKGE001039 | PINK1 | BRPK; PARK6 | PTEN induced kinase 1 |
| TCMBANKGE000674 | PDCD1 | CD279; PD-1; PD1; SLEB2; hPD-1; hPD-l; hSLE1 | programmed cell death 1 |
| TCMBANKGE000201 | ESR1 | ER; ESR; ESRA; ESTRR; Era; NR3A1 | estrogen receptor 1 |
| TCMBANKGE011216 | ALDOB | ALDB; ALDO2 | aldolase, fructose-bisphosphate B |
| TCMBANKGE001374 | MBD4 | MED1 | methyl-CpG binding domain 4, DNA glycosylase |
| TCMBANKGE000986 | ERBB2 | CD340; HER-2; HER-2/neu; HER2; MLN 19; NEU; NGL; TKR1 | erb-b2 receptor tyrosine kinase 2 |
| TCMBANKGE000323 | BRCA1 | BRCAI; BRCC1; BROVCA1; FANCS; IRIS; PNCA4; PPP1R53; PSCP; RNF53 | BRCA1 DNA repair associated |
| TCMBANKGE011002 | IKZF1 | CVID13; Hs.54452; IK1; IKAROS; LYF1; LyF-1; PPP1R92; PRO0758; ZNFN1A1 | IKAROS family zinc finger 1 |
| TCMBANKGE009851 | FAP | DPPIV; FAPA; FAPalpha; SIMP | fibroblast activation protein alpha |
| TCMBANKGE002129 | SELENOP | SELP; SEPP; SEPP1; SeP | selenoprotein P |
| TCMBANKGE001532 | ERCC1 | COFS4; RAD10; UV20 | ERCC excision repair 1, endonuclease non-catalytic subunit |
| TCMBANKGE003686 | FANCB | FA2; FAAP90; FAAP95; FAB; FACB | FA complementation group B |
| TCMBANKGE013679 | DICER1 | DCR1; Dicer; Dicer1e; GLOW; HERNA; K12H4.8-LIKE; MNG1; RMSE2 | dicer 1, ribonuclease III |
| TCMBANKGE008621 | TYMS | HST422; TMS; TS | thymidylate synthetase |
| TCMBANKGE001097 | HIF1A | HIF-1-alpha; HIF-1A; HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8; bHLHe78 | hypoxia inducible factor 1 subunit alpha |
| TCMBANKGE001073 | PTGS2 | COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 | prostaglandin-endoperoxide synthase 2 |
| TCMBANKGE010973 | EPCAM | DIAR5; EGP-2; EGP314; EGP40; ESA; HNPCC8; KS1/4; KSA; M4S1; MIC18; MK-1; TACSTD1; TROP1 | epithelial cell adhesion molecule |
| TCMBANKGE004266 | AR | AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM | androgen receptor |
| TCMBANKGE000728 | MGMT | - | O-6-methylguanine-DNA methyltransferase |
| TCMBANKGE000307 | PIK3CB | P110BETA; PI3K; PI3KBETA; PIK3C1 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta |
| TCMBANKGE010402 | NF1 | NFNS; VRNF; WSS | neurofibromin 1 |
| TCMBANKGE014357 | CHFR | RNF116; RNF196 | checkpoint with forkhead and ring finger domains |
| TCMBANKGE001018 | MUC2 | MLP; MUC-2; SMUC | mucin 2, oligomeric mucus/gel-forming |
| TCMBANKGE001062 | PLK1 | PLK; STPK13 | polo like kinase 1 |
| TCMBANKGE010461 | MSH6 | GTBP; GTMBP; HNPCC5; HSAP; p160 | mutS homolog 6 |
| TCMBANKGE001100 | MIR155 | MIRN155; miRNA155; mir-155 | microRNA 155 |
| TCMBANKGE000886 | SOX9 | CMD1; CMPD1; SRA1; SRXX2; SRXY10 | SRY-box transcription factor 9 |
| TCMBANKGE001170 | CDK4 | CMM3; PSK-J3 | cyclin dependent kinase 4 |
| TCMBANKGE001160 | CD274 | B7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1; hPD-L1 | CD274 molecule |
| TCMBANKGE008240 | MSH2 | COCA1; FCC1; HNPCC; HNPCC1; LCFS2; hMSH2 | mutS homolog 2 |
| TCMBANKGE014820 | MUC6 | MUC-6 | mucin 6, oligomeric mucus/gel-forming |
| TCMBANKGE008722 | APC | BTPS2; DESMD; DP2; DP2.5; DP3; GS; PPP1R46 | APC regulator of WNT signaling pathway |
| TCMBANKGE011348 | IGF2R | CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R; MPR 300; MPR1; MPR300; MPRI | insulin like growth factor 2 receptor |
| TCMBANKGE005003 | CCNO | CCNU; CILD29; UDG2 | cyclin O |
| TCMBANKGE010831 | BAAT | BACAT; BAT | bile acid-CoA:amino acid N-acyltransferase |
| TCMBANKGE001012 | FOXP3 | AIID; DIETER; IPEX; JM2; PIDX; XPID | forkhead box P3 |
| TCMBANKGE001155 | CASP7 | CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3 | caspase 7 |
| TCMBANKGE002431 | ARID1A | B120; BAF250; BAF250a; BM029; C1orf4; CSS2; ELD; MRD14; OSA1; P270; SMARCF1; hELD; hOSA1 | AT-rich interaction domain 1A |
| TCMBANKGE000908 | MUC5AC | MUC5; TBM; leB; mucin | mucin 5AC, oligomeric mucus/gel-forming |
| TCMBANKGE001056 | KRAS | C-K-RAS; C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; K-Ras; K-Ras 2; KI-RAS; KRAS1; KRAS2; NS; NS3; OES; RALD; RASK2; c-Ki-ras; c-Ki-ras2 | KRAS proto-oncogene, GTPase |
| TCMBANKGE008175 | PMS1 | HNPCC3; MLH2; PMSL1; hPMS1 | PMS1 homolog 1, mismatch repair system component |
| TCMBANKGE011172 | MLH3 | HNPCC7 | mutL homolog 3 |
| TCMBANKGE004635 | MDC1 | NFBD1 | mediator of DNA damage checkpoint 1 |
| TCMBANKGE014100 | PMS2 | HNPCC4; MLH4; PMS2CL; PMSL2 | PMS1 homolog 2, mismatch repair system component |
| TCMBANKGE015087 | MRC1 | CD206; CLEC13D; CLEC13DL; MMR; MRC1L1; bA541I19.1; hMR | mannose receptor C-type 1 |
| TCMBANKGE006877 | MLH1 | COCA2; FCC2; HNPCC; HNPCC2; hMLH1 | mutL homolog 1 |
| TCMBANKGE000774 | PRRT2 | BFIC2; BFIS2; DSPB3; DYT10; EKD1; FICCA; ICCA; IFITMD1; PKC | proline rich transmembrane protein 2 |
| TCMBANKGE004203 | TGFBR2 | AAT3; FAA3; LDS1B; LDS2; LDS2B; MFS2; RIIC; TAAD2; TBR-ii; TBRII; TGFR-2; TGFbeta-RII | transforming growth factor beta receptor 2 |
| TCMBANKGE013015 | FBXO11 | FBX11; IDDFBA; PRMT9; UBR6; UG063H01; VIT1 | F-box protein 11 |
| TCMBANKGE009774 | MSH3 | DUP; FAP4; MRP1 | mutS homolog 3 |
| TCMBANKGE000147 | OPA1 | BERHS; MGM1; MTDPS14; NPG; NTG; largeG | OPA1 mitochondrial dynamin like GTPase |
| TCMBANKGE006291 | POLE | CRCS12; FILS; IMAGEI; POLE1 | DNA polymerase epsilon, catalytic subunit |
| TCMBANKGE000639 | HRAS | C-BAS/HAS; C-H-RAS; C-HA-RAS1; CTLO; H-RASIDX; HAMSV; HRAS1; RASH1; p21ras | HRas proto-oncogene, GTPase |
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Dai SX Lab