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疾病ID:TCMBANKDI011480
疾病名:Bicuspid aortic valve
MeSH_Name:Cardiovascular Diseases
HPO_Name:Abnormality of the cardiovascular system
UMLS_Name:Congenital Abnormality
DO_Name:disease of anatomical entity
疾病类型:disease
DisGeNET_Link:C0149630
MeSH_Link:C14
HPO_Link:HP:0001626
UMLS_Link:T019
DO_Link:DOID:7
HERB_ID:HBDIS003456
疾病对应的植物
| ID | 拉丁名 | 药名 | 药用植物名 | 功能与主治 | 来源 | 药用部位 | 使用民族 |
|---|
疾病对应的化合物
| 化合物ID | 化合物名 | 别名 | 分子式 | 分子质量 | Smiles |
|---|
疾病对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE012965 | DSG1 | CDHF4; DG1; DSG; EPKHE; EPKHIA; PPKS1; SPPK1 | desmoglein 1 |
| TCMBANKGE001180 | SMAD3 | HSPC193; HsT17436; JV15-2; LDS1C; LDS3; MADH3 | SMAD family member 3 |
| TCMBANKGE000911 | ITK | EMT; LPFS1; LYK; PSCTK2 | IL2 inducible T cell kinase |
| TCMBANKGE000857 | AHSA1 | AHA1; C14orf3; hAha1; p38 | activator of HSP90 ATPase activity 1 |
| TCMBANKGE001104 | TGFB2 | G-TSF; LDS4; TGF-beta2 | transforming growth factor beta 2 |
| TCMBANKGE000742 | SMAD7 | CRCS3; MADH7; MADH8 | SMAD family member 7 |
| TCMBANKGE001197 | FOS | AP-1; C-FOS; p55 | Fos proto-oncogene, AP-1 transcription factor subunit |
| TCMBANKGE008825 | LTBP4 | ARCL1C; LTBP-4; LTBP4L; LTBP4S | latent transforming growth factor beta binding protein 4 |
| TCMBANKGE013080 | MLXIPL | CHREBP; MIO; MLX; MONDOB; WBSCR14; WS-bHLH; bHLHd14 | MLX interacting protein like |
| TCMBANKGE009341 | PACS1 | MRD17; SHMS | phosphofurin acidic cluster sorting protein 1 |
| TCMBANKGE004124 | CRELD1 | AVSD2; CIRRIN | cysteine rich with EGF like domains 1 |
| TCMBANKGE010711 | ABCC9 | ABC37; ATFB12; CANTU; CMD1O; SUR2 | ATP binding cassette subfamily C member 9 |
| TCMBANKGE000827 | CBL | C-CBL; CBL2; FRA11B; NSLL; RNF55 | Cbl proto-oncogene |
| TCMBANKGE000313 | JUN | AP-1; AP1; c-Jun; cJUN; p39 | Jun proto-oncogene, AP-1 transcription factor subunit |
| TCMBANKGE001015 | RAC1 | MIG5; MRD48; Rac-1; TC-25; p21-Rac1 | Rac family small GTPase 1 |
| TCMBANKGE001076 | SOD2 | GClnc1; IPO-B; IPOB; MNSOD; MVCD6; Mn-SOD | superoxide dismutase 2 |
| TCMBANKGE011458 | CLIP2 | CLIP; CLIP-115; CYLN2; WBSCR3; WBSCR4; WSCR3; WSCR4 | CAP-Gly domain containing linker protein 2 |
| TCMBANKGE009966 | ACAN | AGC1; AGCAN; CSPG1; CSPGCP; MSK16; SEDK; SSOAOD | aggrecan |
| TCMBANKGE000311 | JUND | AP-1 | JunD proto-oncogene, AP-1 transcription factor subunit |
| TCMBANKGE000229 | ACE2 | ACEH | angiotensin I converting enzyme 2 |
| TCMBANKGE004515 | NXN | NRX; RRS2; TRG-4 | nucleoredoxin |
| TCMBANKGE004283 | FBN2 | CCA; DA9; EOMD | fibrillin 2 |
| TCMBANKGE008315 | SLC9A3R2 | E3KARP; NHE3RF2; NHERF-2; NHERF2; OCTS2; SIP-1; SIP1; TKA-1 | SLC9A3 regulator 2 |
| TCMBANKGE000047 | AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | AKT serine/threonine kinase 1 |
| TCMBANKGE011747 | MATR3 | ALS21; MPD2; VCPDM | matrin 3 |
| TCMBANKGE012553 | TNC | 150-225; DFNA56; GMEM; GP; HXB; JI; TN; TN-C | tenascin C |
| TCMBANKGE000298 | SOD1 | ALS; ALS1; HEL-S-44; IPOA; SOD; STAHP; hSod1; homodimer | superoxide dismutase 1 |
| TCMBANKGE001203 | MAPK1 | ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK | mitogen-activated protein kinase 1 |
| TCMBANKGE010134 | MYH11 | AAT4; FAA4; SMHC; SMMHC | myosin heavy chain 11 |
| TCMBANKGE000132 | MAT2A | MATA2; MATII; SAMS2 | methionine adenosyltransferase 2A |
| TCMBANKGE000282 | ELN | ADCL1; SVAS; WBS; WS | elastin |
| TCMBANKGE010657 | PRKG1 | AAT8; PKG; PKG1; PRKG1B; PRKGR1B; cGK; cGK 1; cGK1; cGKI; cGKI-BETA; cGKI-alpha | protein kinase cGMP-dependent 1 |
| TCMBANKGE011049 | TAB2 | CHTD2; MAP3K7IP2; TAB-2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2 |
| TCMBANKGE000905 | GATA6 | - | GATA binding protein 6 |
| TCMBANKGE013523 | ENG | END; HHT1; ORW1 | endoglin |
| TCMBANKGE013099 | SMAD6 | AOVD2; HsT17432; MADH6; MADH7 | SMAD family member 6 |
| TCMBANKGE001107 | NOS3 | ECNOS; eNOS | nitric oxide synthase 3 |
| TCMBANKGE000929 | MIR145 | MIRN145; miR-145; miRNA145 | microRNA 145 |
| TCMBANKGE001037 | MMP2 | CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1 | matrix metallopeptidase 2 |
| TCMBANKGE009570 | LPA | AK38; APOA; LP | lipoprotein(a) |
| TCMBANKGE000271 | APOE | AD2; APO-E; ApoE4; LDLCQ5; LPG | apolipoprotein E |
| TCMBANKGE013582 | SOD3 | EC-SOD | superoxide dismutase 3 |
| TCMBANKGE005767 | SNIP1 | PML1; PMRED | Smad nuclear interacting protein 1 |
| TCMBANKGE000479 | TIMP1 | CLGI; EPA; EPO; HCI; TIMP; TIMP-1 | TIMP metallopeptidase inhibitor 1 |
| TCMBANKGE000687 | POLDIP2 | PDIP38; POLD4; p38 | DNA polymerase delta interacting protein 2 |
| TCMBANKGE013948 | TGFB3 | ARVD; ARVD1; LDS5; RNHF; TGF-beta3 | transforming growth factor beta 3 |
| TCMBANKGE014531 | ENPP1 | ARHR2; COLED; M6S1; NPP1; NPPS; PC-1; PCA1; PDNP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
| TCMBANKGE001202 | MAPK14 | CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA | mitogen-activated protein kinase 14 |
| TCMBANKGE008891 | ODC1 | ODC | ornithine decarboxylase 1 |
| TCMBANKGE001182 | SIRT1 | SIR2; SIR2L1; SIR2alpha | sirtuin 1 |
| TCMBANKGE004724 | FBN1 | ACMICD; ECTOL1; FBN; GPHYSD2; MASS; MFLS; MFS1; OCTD; SGS; SSKS; WMS; WMS2 | fibrillin 1 |
| TCMBANKGE009185 | MEFV | FMF; MEF; TRIM20 | MEFV innate immuity regulator, pyrin |
| TCMBANKGE000507 | EGR2 | AT591; CHN1; CMT1D; CMT4E; KROX20 | early growth response 2 |
| TCMBANKGE000224 | AGT | ANHU; SERPINA8; hFLT1 | angiotensinogen |
| TCMBANKGE003565 | TGFBR1 | AAT5; ACVRLK4; ALK-5; ALK5; ESS1; LDS1; LDS1A; LDS2A; MSSE; SKR4; TBR-i; TBRI; TGFR-1; tbetaR-I | transforming growth factor beta receptor 1 |
| TCMBANKGE001113 | ACTA2 | ACTSA | actin alpha 2, smooth muscle |
| TCMBANKGE001030 | NOTCH1 | AOS5; AOVD1; TAN1; hN1 | notch receptor 1 |
| TCMBANKGE000616 | SLC7A1 | ATRC1; CAT-1; ERR; HCAT1; REC1L | solute carrier family 7 member 1 |
| TCMBANKGE010402 | NF1 | NFNS; VRNF; WSS | neurofibromin 1 |
| TCMBANKGE002190 | SLC25A24 | APC1; SCAMC-1; SCAMC1 | solute carrier family 25 member 24 |
| TCMBANKGE006020 | UBC | HMG20 | ubiquitin C |
| TCMBANKGE014967 | GATA5 | CHTD5; GATAS; bB379O24.1 | GATA binding protein 5 |
| TCMBANKGE005310 | HMCN2 | - | hemicentin 2 |
| TCMBANKGE009848 | ARSD | ASD | arylsulfatase D |
| TCMBANKGE000273 | LOX | AAT10 | lysyl oxidase |
| TCMBANKGE001697 | MMP1 | CLG; CLGN | matrix metallopeptidase 1 |
| TCMBANKGE001959 | B3GAT3 | GLCATI; JDSCD; glcUAT-I | beta-1,3-glucuronyltransferase 3 |
| TCMBANKGE006005 | GATA4 | ASD2; TACHD; TOF; VSD1 | GATA binding protein 4 |
| TCMBANKGE008936 | IFT122 | CED; CED1; FAP80; SPG; WDR10; WDR10p; WDR140 | intraflagellar transport 122 |
| TCMBANKGE000431 | NKX2-5 | CHNG5; CSX; CSX1; HLHS2; NKX2.5; NKX2E; NKX4-1; VSD3 | NK2 homeobox 5 |
| TCMBANKGE000677 | LRP5 | BMND1; EVR1; EVR4; HBM; LR3; LRP-5; LRP-7; LRP7; OPPG; OPS; OPTA1; PCLD4; VBCH2 | LDL receptor related protein 5 |
| TCMBANKGE000910 | SLC22A3 | EMT; EMTH; OCT3 | solute carrier family 22 member 3 |
| TCMBANKGE014949 | ROBO4 | AOVD3; ECSM4; MRB | roundabout guidance receptor 4 |
| TCMBANKGE005541 | GTF2IRD1 | BEN; CREAM1; GTF3; MUSTRD1; RBAP2; WBS; WBSCR11; WBSCR12; hMusTRD1alpha1 | GTF2I repeat domain containing 1 |
| TCMBANKGE011098 | NR2F2 | ARP-1; ARP1; CHTD4; COUPTF2; COUPTFB; COUPTFII; NF-E3; SVP40; TFCOUP2 | nuclear receptor subfamily 2 group F member 2 |
| TCMBANKGE000310 | FOSB | AP-1; G0S3; GOS3; GOSB | FosB proto-oncogene, AP-1 transcription factor subunit |
| TCMBANKGE003496 | ATP6 | ATPase6; MTATP6 | ATP synthase F0 subunit 6 |
| TCMBANKGE008490 | RNF19A | RNF19 | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| TCMBANKGE000109 | ACTB | BRWS1; PS1TP5BP1 | actin beta |
| TCMBANKGE014172 | SSH3 | SSH3L | slingshot protein phosphatase 3 |
| TCMBANKGE004967 | PDIA2 | PDA2; PDI; PDIP; PDIR | protein disulfide isomerase family A member 2 |
| TCMBANKGE000964 | MAP3K7 | CSCF; FMD2; MEKK7; TAK1; TGF1a | mitogen-activated protein kinase kinase kinase 7 |
| TCMBANKGE004970 | CHST3 | C6ST; C6ST1; HSD | carbohydrate sulfotransferase 3 |
| TCMBANKGE008818 | TTC37 | KIAA0372; Ski3; THES | tetratricopeptide repeat domain 37 |
| TCMBANKGE000856 | CRK | CRKII; p38 | CRK proto-oncogene, adaptor protein |
| TCMBANKGE004968 | FGF8 | AIGF; FGF-8; HBGF-8; HH6; KAL6 | fibroblast growth factor 8 |
| TCMBANKGE005941 | FLNA | ABP-280; ABPX; CSBS; CVD1; FGS2; FLN; FLN-A; FLN1; FMD; MNS; NHBP; OPD; OPD1; OPD2; XLVD; XMVD | filamin A |
| TCMBANKGE007130 | BCOR | ANOP2; MAA2; MCOPS2 | BCL6 corepressor |
| TCMBANKGE007431 | RFC2 | RFC40 | replication factor C subunit 2 |
| TCMBANKGE005692 | TRPV6 | ABP/ZF; CAT1; CATL; ECAC2; HRPTTN; HSA277909; LP6728; ZFAB | transient receptor potential cation channel subfamily V member 6 |
| TCMBANKGE000689 | GRAP2 | GADS; GRAP-2; GRB2L; GRBLG; GRID; GRPL; GrbX; Grf40; Mona; P38 | GRB2 related adaptor protein 2 |
| TCMBANKGE000145 | ADAMTS5 | ADAM-TS 11; ADAM-TS 5; ADAM-TS5; ADAMTS-11; ADAMTS-5; ADAMTS11; ADMP-2 | ADAM metallopeptidase with thrombospondin type 1 motif 5 |
| TCMBANKGE000884 | FN1 | CIG; ED-B; FINC; FN; FNZ; GFND; GFND2; LETS; MSF; SMDCF | fibronectin 1 |
| TCMBANKGE009748 | BAZ1B | WBSCR10; WBSCR9; WSTF | bromodomain adjacent to zinc finger domain 1B |
| TCMBANKGE000747 | GAPDH | G3PD; GAPD; HEL-S-162eP | glyceraldehyde-3-phosphate dehydrogenase |
| TCMBANKGE000885 | SPP1 | BNSP; BSPI; ETA-1; OPN | secreted phosphoprotein 1 |
| TCMBANKGE006097 | FLNC | ABP-280; ABP280A; ABPA; ABPL; CMH26; FLN2; MFM5; MPD4; RCM5 | filamin C |
| TCMBANKGE001096 | TLR4 | ARMD10; CD284; TLR-4; TOLL | toll like receptor 4 |
| TCMBANKGE013106 | TIMP3 | HSMRK222; K222; K222TA2; SFD | TIMP metallopeptidase inhibitor 3 |
| TCMBANKGE001201 | MAPK3 | ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; p44-ERK1; p44-MAPK | mitogen-activated protein kinase 3 |
| TCMBANKGE000846 | MMP14 | MMP-14; MMP-X1; MT-MMP; MT-MMP 1; MT1-MMP; MT1MMP; MTMMP1; WNCHRS | matrix metallopeptidase 14 |
| TCMBANKGE008292 | PITX1 | BFT; CCF; LBNBG; POTX; PTX1 | paired like homeodomain 1 |
| TCMBANKGE007018 | RPL26 | DBA11; L26 | ribosomal protein L26 |
| TCMBANKGE012330 | LIMK1 | LIMK; LIMK-1 | LIM domain kinase 1 |
| TCMBANKGE000312 | JUNB | AP-1 | JunB proto-oncogene, AP-1 transcription factor subunit |
| TCMBANKGE000972 | MIR17 | MIR17-5p; MIR91; MIRN17; MIRN91; hsa-mir-17; miR-17; miR17-3p; miRNA17; miRNA91 | microRNA 17 |
| TCMBANKGE005300 | PLOD1 | EDS6; EDSKCL1; LH; LH1; LLH; PLOD | procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 |
| TCMBANKGE008786 | CRAT | CAT; CAT1; NBIA8 | carnitine O-acetyltransferase |
| TCMBANKGE009810 | NAA10 | ARD1; ARD1A; ARD1P; DXS707; MCOPS1; NATD; OGDNS; TE2; hARD1 | N-alpha-acetyltransferase 10, NatA catalytic subunit |
| TCMBANKGE013828 | APLN | APEL; XNPEP2 | apelin |
| TCMBANKGE000688 | AIMP2 | HLD17; JTV-1; JTV1; P38 | aminoacyl tRNA synthetase complex interacting multifunctional protein 2 |
| TCMBANKGE005627 | LTBP3 | DASS; GPHYSD3; LTBP-3; LTBP2; STHAG6; pp6425 | latent transforming growth factor beta binding protein 3 |
| TCMBANKGE012951 | MYLK | AAT7; KRP; MLCK; MLCK1; MLCK108; MLCK210; MMIHS; MSTP083; MYLK1; smMLCK | myosin light chain kinase |
| TCMBANKGE004203 | TGFBR2 | AAT3; FAA3; LDS1B; LDS2; LDS2B; MFS2; RIIC; TAAD2; TBR-ii; TBRII; TGFR-2; TGFbeta-RII | transforming growth factor beta receptor 2 |
| TCMBANKGE014573 | QRSL1 | COXPD40; GatA | glutaminyl-tRNA amidotransferase subunit QRSL1 |
| TCMBANKGE002760 | MFAP5 | AAT9; MAGP-2; MAGP2; MFAP-5; MP25 | microfibril associated protein 5 |
| TCMBANKGE012516 | DSP | DCWHKTA; DP | desmoplakin |
| TCMBANKGE004208 | AXIN1 | AXIN; PPP1R49 | axin 1 |
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Dai SX Lab