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疾病ID:TCMBANKDI012012
疾病名:Aggressive Periodontitis
MeSH_Name:Stomatognathic Diseases
HPO_Name:-
UMLS_Name:Disease or Syndrome
DO_Name:disease of anatomical entity
疾病类型:disease
DisGeNET_Link:C0031106
MeSH_Link:C07
HPO_Link:-
UMLS_Link:T047
DO_Link:DOID:7
HERB_ID:HBDIS002359
疾病对应的植物
| ID | 拉丁名 | 药名 | 药用植物名 | 功能与主治 | 来源 | 药用部位 | 使用民族 |
|---|
疾病对应的化合物
| 化合物ID | 化合物名 | 别名 | 分子式 | 分子质量 | Smiles |
|---|
疾病对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE000573 | CDX2 | CDX-3; CDX2/AS; CDX3 | caudal type homeobox 2 |
| TCMBANKGE001699 | DEFA1 | DEF1; DEFA2; HNP-1; HP-1; HP1; MRS | defensin alpha 1 |
| TCMBANKGE005143 | FCGR3B | CD16; CD16A; CD16b; FCG3; FCGR3; FCGR3A; FCR-10; FCRIII; FCRIIIb | Fc fragment of IgG receptor IIIb |
| TCMBANKGE001067 | S100A8 | 60B8AG; CAGA; CFAG; CGLA; CP-10; L1Ag; MA387; MIF; MRP8; NIF; P8 | S100 calcium binding protein A8 |
| TCMBANKGE001079 | CYP1A1 | AHH; AHRR; CP11; CYP1; CYPIA1; P1-450; P450-C; P450DX | cytochrome P450 family 1 subfamily A member 1 |
| TCMBANKGE000562 | IL18 | IGIF; IL-18; IL-1g; IL1F4 | interleukin 18 |
| TCMBANKGE004292 | GLT6D1 | GLTDC1; GT6M7 | glycosyltransferase 6 domain containing 1 |
| TCMBANKGE000742 | SMAD7 | CRCS3; MADH7; MADH8 | SMAD family member 7 |
| TCMBANKGE000567 | CDKN2A | ARF; CDK4I; CDKN2; CMM2; INK4; INK4A; MLM; MTS-1; MTS1; P14; P14ARF; P16; P16-INK4A; P16INK4; P16INK4A; P19; P19ARF; TP16 | cyclin dependent kinase inhibitor 2A |
| TCMBANKGE001120 | CAMP | CAP-18; CAP18; CRAMP; FALL-39; FALL39; HSD26; LL37 | cathelicidin antimicrobial peptide |
| TCMBANKGE005638 | NOD1 | CARD4; CLR7.1; NLRC1 | nucleotide binding oligomerization domain containing 1 |
| TCMBANKGE001130 | BAD | BBC2; BCL2L8 | BCL2 associated agonist of cell death |
| TCMBANKGE000395 | CXCL9 | CMK; Humig; MIG; SCYB9; crg-10 | C-X-C motif chemokine ligand 9 |
| TCMBANKGE004616 | RBM45 | DRB1; RB-1 | RNA binding motif protein 45 |
| TCMBANKGE013010 | COX2 | COII; MTCO2 | cytochrome c oxidase subunit II |
| TCMBANKGE000486 | IL2RA | CD25; IDDM10; IL2R; IMD41; TCGFR; p55 | interleukin 2 receptor subunit alpha |
| TCMBANKGE008380 | IRF5 | SLEB10 | interferon regulatory factor 5 |
| TCMBANKGE000917 | IL17RA | CANDF5; CD217; CDw217; IL-17RA; IL17R; IMD51; hIL-17R | interleukin 17 receptor A |
| TCMBANKGE000433 | IL37 | FIL1; FIL1(ZETA); FIL1Z; IL-1F7; IL-1H; IL-1H4; IL-1RP1; IL-37; IL1F7; IL1H4; IL1RP1 | interleukin 37 |
| TCMBANKGE000274 | CCL2 | GDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; SCYA2; SMC-CF | C-C motif chemokine ligand 2 |
| TCMBANKGE000241 | CASP8 | ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5 | caspase 8 |
| TCMBANKGE009021 | HLA-DQB1 | CELIAC1; HLA-DQB; IDDM1 | major histocompatibility complex, class II, DQ beta 1 |
| TCMBANKGE000701 | ESR2 | ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 | estrogen receptor 2 |
| TCMBANKGE004687 | TREM1 | CD354; TREM-1 | triggering receptor expressed on myeloid cells 1 |
| TCMBANKGE003252 | HTRA1 | ARMD7; CADASIL2; CARASIL; HtrA; L56; ORF480; PRSS11 | HtrA serine peptidase 1 |
| TCMBANKGE004819 | EEFSEC | EFSEC; SELB | eukaryotic elongation factor, selenocysteine-tRNA specific |
| TCMBANKGE014769 | POSTN | OSF-2; OSF2; PDLPOSTN; PN | periostin |
| TCMBANKGE000205 | NOS2 | HEP-NOS; INOS; NOS; NOS2A | nitric oxide synthase 2 |
| TCMBANKGE000872 | IGF1R | CD221; IGFIR; IGFR; JTK13 | insulin like growth factor 1 receptor |
| TCMBANKGE010860 | PI3 | ESI; SKALP; WAP3; WFDC14; cementoin | peptidase inhibitor 3 |
| TCMBANKGE014979 | NOD2 | ACUG; BLAU; BLAUS; CARD15; CD; CLR16.3; IBD1; NLRC2; NOD2B; PSORAS1; YAOS | nucleotide binding oligomerization domain containing 2 |
| TCMBANKGE006522 | HLA-C | D6S204; HLA-JY3; HLAC; HLC-C; MHC; PSORS1 | major histocompatibility complex, class I, C |
| TCMBANKGE004935 | FCGR2A | CD32; CD32A; CDw32; FCG2; FCGR2; FCGR2A1; FcGR; IGFR2 | Fc fragment of IgG receptor IIa |
| TCMBANKGE012838 | INHA | - | inhibin subunit alpha |
| TCMBANKGE008068 | PRTN3 | ACPA; AGP7; C-ANCA; CANCA; MBN; MBT; NP-4; NP4; P29; PR-3; PR3 | proteinase 3 |
| TCMBANKGE011334 | CSF3 | C17orf33; CSF3OS; GCSF | colony stimulating factor 3 |
| TCMBANKGE001674 | IL17C | CX2; IL-17C | interleukin 17C |
| TCMBANKGE000282 | ELN | ADCL1; SVAS; WBS; WS | elastin |
| TCMBANKGE009373 | MMP8 | CLG1; HNC; MMP-8; PMNL-CL | matrix metallopeptidase 8 |
| TCMBANKGE013197 | FCGR3A | CD16; CD16A; FCG3; FCGR3; FCGRIII; FCR-10; FCRIII; FCRIIIA; IGFR3; IMD20 | Fc fragment of IgG receptor IIIa |
| TCMBANKGE003237 | ADAM23 | MDC-3; MDC3 | ADAM metallopeptidase domain 23 |
| TCMBANKGE001034 | TLR2 | CD282; TIL4 | toll like receptor 2 |
| TCMBANKGE013153 | IL1R2 | CD121b; CDw121b; IL-1R-2; IL-1RT-2; IL-1RT2; IL1R2c; IL1RB | interleukin 1 receptor type 2 |
| TCMBANKGE000699 | CYBA | p22-PHOX | cytochrome b-245 alpha chain |
| TCMBANKGE009214 | KCNJ5 | CIR; GIRK4; KATP1; KIR3.4; LQT13 | potassium inwardly rectifying channel subfamily J member 5 |
| TCMBANKGE010265 | ISG20 | CD25; HEM45 | interferon stimulated exonuclease gene 20 |
| TCMBANKGE001069 | MPO | - | myeloperoxidase |
| TCMBANKGE001037 | MMP2 | CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1 | matrix metallopeptidase 2 |
| TCMBANKGE000154 | CCR2 | CC-CKR-2; CCR-2; CCR2A; CCR2B; CD192; CKR2; CKR2A; CKR2B; CMKBR2; MCP-1-R | C-C motif chemokine receptor 2 |
| TCMBANKGE006885 | APOH | B2G1; B2GP1; BG | apolipoprotein H |
| TCMBANKGE010148 | CKAP2L | - | cytoskeleton associated protein 2 like |
| TCMBANKGE014933 | GC | DBP; DBP-maf; DBP/GC; GRD3; Gc-MAF; GcMAF; HEL-S-51; VDB; VDBG; VDBP | GC vitamin D binding protein |
| TCMBANKGE000204 | CXCL8 | GCP-1; GCP1; IL8; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1; SCYB8 | C-X-C motif chemokine ligand 8 |
| TCMBANKGE001161 | IL2 | IL-2; TCGF; lymphokine | interleukin 2 |
| TCMBANKGE002113 | CTSC | CPPI; DPP-I; DPP1; DPPI; HMS; JP; JPD; PALS; PDON1; PLS | cathepsin C |
| TCMBANKGE000563 | CLU | AAG4; APO-J; APOJ; CLI; CLU1; CLU2; KUB1; NA1/NA2; SGP-2; SGP2; SP-40; TRPM-2; TRPM2 | clusterin |
| TCMBANKGE013600 | DEFB4A | BD-2; DEFB-2; DEFB102; DEFB2; DEFB4; HBD-2; SAP1 | defensin beta 4A |
| TCMBANKGE000037 | CSF1 | CSF-1; MCSF | colony stimulating factor 1 |
| TCMBANKGE003789 | HLA-DQA1 | CELIAC1; DQ-A1; DQA1; HLA-DQA | major histocompatibility complex, class II, DQ alpha 1 |
| TCMBANKGE003415 | GATA3 | HDR; HDRS | GATA binding protein 3 |
| TCMBANKGE012841 | HLA-A | HLAA | major histocompatibility complex, class I, A |
| TCMBANKGE013026 | HSPD1 | CPN60; GROEL; HLD4; HSP-60; HSP60; HSP65; HuCHA60; SPG13 | heat shock protein family D (Hsp60) member 1 |
| TCMBANKGE003633 | HSPA14 | HSP70-4; HSP70L1 | heat shock protein family A (Hsp70) member 14 |
| TCMBANKGE013556 | ZNF136 | pHZ-20 | zinc finger protein 136 |
| TCMBANKGE001073 | PTGS2 | COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 | prostaglandin-endoperoxide synthase 2 |
| TCMBANKGE000587 | ITGAM | CD11B; CR3A; MAC-1; MAC1A; MO1A; SLEB6 | integrin subunit alpha M |
| TCMBANKGE001030 | NOTCH1 | AOS5; AOVD1; TAN1; hN1 | notch receptor 1 |
| TCMBANKGE000730 | HSPB2 | HSP27; Hs.78846; LOH11CR1K; MKBP | heat shock protein family B (small) member 2 |
| TCMBANKGE000163 | TNFRSF1B | CD120b; TBPII; TNF-R-II; TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80; p75; p75TNFR | TNF receptor superfamily member 1B |
| TCMBANKGE001101 | CCL3 | G0S19-1; LD78ALPHA; MIP-1-alpha; MIP1A; SCYA3 | C-C motif chemokine ligand 3 |
| TCMBANKGE004763 | TGFBRAP1 | TRAP-1; TRAP1; VPS3 | transforming growth factor beta receptor associated protein 1 |
| TCMBANKGE008871 | SLC23A1 | SLC23A2; SVCT1; YSPL3 | solute carrier family 23 member 1 |
| TCMBANKGE004843 | UBE3D | C6orf157; H10BH; UBE2CBP; YJR141W | ubiquitin protein ligase E3D |
| TCMBANKGE012277 | MMP25 | MMP-25; MMP20; MMP20A; MMPL1; MT-MMP 6; MT-MMP6; MT6-MMP; MT6MMP; MTMMP6 | matrix metallopeptidase 25 |
| TCMBANKGE003331 | IL20 | IL-20; IL10D; ZCYTO10 | interleukin 20 |
| TCMBANKGE001088 | SMAD4 | DPC4; JIP; MADH4; MYHRS | SMAD family member 4 |
| TCMBANKGE000681 | TNFRSF11B | OCIF; OPG; PDB5; TR1 | TNF receptor superfamily member 11b |
| TCMBANKGE000394 | CXCR3 | CD182; CD183; CKR-L2; CMKAR3; GPR9; IP10-R; Mig-R; MigR | C-X-C motif chemokine receptor 3 |
| TCMBANKGE006400 | PLG | - | plasminogen |
| TCMBANKGE001697 | MMP1 | CLG; CLGN | matrix metallopeptidase 1 |
| TCMBANKGE001018 | MUC2 | MLP; MUC-2; SMUC | mucin 2, oligomeric mucus/gel-forming |
| TCMBANKGE000787 | VCAM1 | CD106; INCAM-100 | vascular cell adhesion molecule 1 |
| TCMBANKGE007217 | FCAR | CD89; CTB-61M7.2; FcalphaRI | Fc fragment of IgA receptor |
| TCMBANKGE001131 | CASP9 | APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 | caspase 9 |
| TCMBANKGE006686 | PRDM1 | BLIMP1; PRDI-BF1 | PR/SET domain 1 |
| TCMBANKGE004403 | DGKA | DAGK; DAGK1; DGK-alpha | diacylglycerol kinase alpha |
| TCMBANKGE000428 | SERPINA1 | A1A; A1AT; AAT; PI; PI1; PRO2275; alpha1AT; nNIF | serpin family A member 1 |
| TCMBANKGE001188 | CXCL10 | C7; IFI10; INP10; IP-10; SCYB10; crg-2; gIP-10; mob-1 | C-X-C motif chemokine ligand 10 |
| TCMBANKGE011287 | CFB | AHUS4; ARMD14; BF; BFD; CFAB; CFBD; FB; FBI12; GBG; H2-Bf; PBF2 | complement factor B |
| TCMBANKGE008612 | KRT23 | CK23; HAIK1; K23 | keratin 23 |
| TCMBANKGE000961 | MBL2 | COLEC1; HSMBPC; MBL; MBL2D; MBP; MBP-C; MBP1; MBPD | mannose binding lectin 2 |
| TCMBANKGE011657 | PES1 | NOP7; PES | pescadillo ribosomal biogenesis factor 1 |
| TCMBANKGE007624 | CD28 | Tp44 | CD28 molecule |
| TCMBANKGE006553 | PON1 | ESA; MVCD5; PON | paraoxonase 1 |
| TCMBANKGE009400 | GNAS | AHO; C20orf45; GNAS1; GPSA; GSA; GSP; NESP; PITA3; POH; SCG6; SgVI | GNAS complex locus |
| TCMBANKGE012879 | DEFB1 | BD1; DEFB-1; DEFB101; HBD1 | defensin beta 1 |
| TCMBANKGE014820 | MUC6 | MUC-6 | mucin 6, oligomeric mucus/gel-forming |
| TCMBANKGE001159 | STAT1 | CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91 | signal transducer and activator of transcription 1 |
| TCMBANKGE002000 | CTLA4 | ALPS5; CD; CD152; CELIAC3; CTLA-4; GRD4; GSE; IDDM12 | cytotoxic T-lymphocyte associated protein 4 |
| TCMBANKGE004611 | IL24 | C49A; FISP; IL10B; MDA7; MOB5; ST16 | interleukin 24 |
| TCMBANKGE009874 | CDKN2B | CDK4I; INK4B; MTS2; P15; TP15; p15INK4b | cyclin dependent kinase inhibitor 2B |
| TCMBANKGE001144 | CD14 | - | CD14 molecule |
| TCMBANKGE000469 | CTSD | CLN10; CPSD; HEL-S-130P | cathepsin D |
| TCMBANKGE000679 | BTF3P11 | BTF3L1; HUMBTFB; OCIF; OPG; TNFRSF11B | basic transcription factor 3 pseudogene 11 |
| TCMBANKGE004793 | WNT5A | hWNT5A | Wnt family member 5A |
| TCMBANKGE009742 | HLA-DRB1 | DRB1; HLA-DR1B; HLA-DRB; SS1 | major histocompatibility complex, class II, DR beta 1 |
| TCMBANKGE009543 | LTA | LT; TNFB; TNFSF1; TNLG1E | lymphotoxin alpha |
| TCMBANKGE004054 | MKLN1 | TWA2 | muskelin 1 |
| TCMBANKGE008602 | KLF6 | BCD1; CBA1; COPEB; CPBP; GBF; PAC1; ST12; ZF9 | Kruppel like factor 6 |
| TCMBANKGE000908 | MUC5AC | MUC5; TBM; leB; mucin | mucin 5AC, oligomeric mucus/gel-forming |
| TCMBANKGE000646 | DECR1 | DECR; NADPH; SDR18C1 | 2,4-dienoyl-CoA reductase 1 |
| TCMBANKGE000240 | IL17A | CTLA-8; CTLA8; IL-17; IL-17A; IL17 | interleukin 17A |
| TCMBANKGE000058 | SCN4A | CMS16; HOKPP2; HYKPP; HYPP; NAC1A; Na(V)1.4; Nav1.4; SkM1 | sodium voltage-gated channel alpha subunit 4 |
| TCMBANKGE000219 | CCR5 | CC-CKR-5; CCCKR5; CCR-5; CD195; CKR-5; CKR5; CMKBR5; IDDM22 | C-C motif chemokine receptor 5 |
| TCMBANKGE005557 | LCN2 | 24p3; MSFI; NGAL; p25 | lipocalin 2 |
| TCMBANKGE012048 | HLA-B | AS; B-4901; HLAB | major histocompatibility complex, class I, B |
| TCMBANKGE001317 | FPR1 | FMLP; FPR | formyl peptide receptor 1 |
| TCMBANKGE003850 | POPDC2 | POP2 | popeye domain containing 2 |
| TCMBANKGE001189 | IL1A | IL-1 alpha; IL-1A; IL1; IL1-ALPHA; IL1F1 | interleukin 1 alpha |
| TCMBANKGE001096 | TLR4 | ARMD10; CD284; TLR-4; TOLL | toll like receptor 4 |
| TCMBANKGE001732 | ITGAL | CD11A; LFA-1; LFA1A | integrin subunit alpha L |
| TCMBANKGE000749 | ALOX5 | 5-LO; 5-LOX; 5LPG; LOG5 | arachidonate 5-lipoxygenase |
| TCMBANKGE000788 | SELE | CD62E; ELAM; ELAM1; ESEL; LECAM2 | selectin E |
| TCMBANKGE009263 | IL12RB2 | - | interleukin 12 receptor subunit beta 2 |
| TCMBANKGE014572 | TPO | MSA; TDH2A; TPX | thyroid peroxidase |
| TCMBANKGE000333 | CCR6 | BN-1; C-C CKR-6; CC-CKR-6; CCR-6; CD196; CKR-L3; CKRL3; CMKBR6; DCR2; DRY6; GPR29; GPRCY4; STRL22 | C-C motif chemokine receptor 6 |
| TCMBANKGE007949 | CNOT8 | CAF1; CALIF; Caf1b; POP2; hCAF1 | CCR4-NOT transcription complex subunit 8 |
| TCMBANKGE009407 | TYK2 | IMD35; JTK1 | tyrosine kinase 2 |
| TCMBANKGE003597 | SFXN1 | SLC56A1; TCC | sideroflexin 1 |
| TCMBANKGE003625 | SLC6A4 | 5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT | solute carrier family 6 member 4 |
| TCMBANKGE014136 | LTF | GIG12; HEL110; HLF2; LF | lactotransferrin |
| TCMBANKGE012224 | VDR | NR1I1; PPP1R163 | vitamin D receptor |
| TCMBANKGE000797 | HSPB1 | CMT2F; HEL-S-102; HMN2B; HS.76067; HSP27; HSP28; Hsp25; SRP27 | heat shock protein family B (small) member 1 |
| TCMBANKGE000389 | MMP3 | CHDS6; MMP-3; SL-1; STMY; STMY1; STR1 | matrix metallopeptidase 3 |
| TCMBANKGE003470 | AP1S3 | PSORS15 | adaptor related protein complex 1 subunit sigma 3 |
| TCMBANKGE007742 | HSPB3 | DHMN2C; HMN2C; HSPL27 | heat shock protein family B (small) member 3 |
| TCMBANKGE005578 | GPRC6A | GPCR; bA86F4.3 | G protein-coupled receptor class C group 6 member A |
| TCMBANKGE007692 | GSTM1 | GST1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GTH4; GTM1; H-B; MU; MU-1 | glutathione S-transferase mu 1 |
| TCMBANKGE011182 | ITGB2 | CD18; LAD; LCAMB; LFA-1; MAC-1; MF17; MFI7 | integrin subunit beta 2 |
| TCMBANKGE014322 | IL23A | IL-23; IL-23A; IL23P19; P19; SGRF | interleukin 23 subunit alpha |
| TCMBANKGE008642 | IL36RN | FIL1; FIL1(DELTA); FIL1D; IL-36Ra; IL1F5; IL1HY1; IL1L1; IL1RP3; IL36RA; PSORP; PSORS14 | interleukin 36 receptor antagonist |
| TCMBANKGE001029 | IL13 | IL-13; P600 | interleukin 13 |
| TCMBANKGE010848 | PAFAH1B1 | LIS1; LIS2; MDCR; MDS; NudF; PAFAH | platelet activating factor acetylhydrolase 1b regulatory subunit 1 |
| TCMBANKGE007151 | TIMP2 | CSC-21K; DDC8 | TIMP metallopeptidase inhibitor 2 |
| TCMBANKGE000075 | IL1RN | DIRA; ICIL-1RA; IL-1RN; IL-1ra; IL-1ra3; IL1F3; IL1RA; IRAP; MVCD4 | interleukin 1 receptor antagonist |
| TCMBANKGE000315 | IL4 | BCGF-1; BCGF1; BSF-1; BSF1; IL-4 | interleukin 4 |
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Dai SX Lab