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疾病ID:TCMBANKDI014817
疾病名:Advanced breast cancer
MeSH_Name:-
HPO_Name:-
UMLS_Name:Neoplastic Process
DO_Name:-
疾病类型:disease
DisGeNET_Link:C3495917
MeSH_Link:-
HPO_Link:-
UMLS_Link:T191
DO_Link:-
HERB_ID:-
疾病对应的植物
| ID | 拉丁名 | 药名 | 药用植物名 | 功能与主治 | 来源 | 药用部位 | 使用民族 |
|---|
疾病对应的化合物
| 化合物ID | 化合物名 | 别名 | 分子式 | 分子质量 | Smiles |
|---|
疾病对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE010665 | CD9 | BTCC-1; DRAP-27; MIC3; MRP-1; TSPAN-29; TSPAN29 | CD9 molecule |
| TCMBANKGE000737 | PGR | NR3C3; PR | progesterone receptor |
| TCMBANKGE000458 | CYP2B6 | CPB6; CYP2B; CYP2B7; CYP2B7P; CYPIIB6; EFVM; IIB1; P450 | cytochrome P450 family 2 subfamily B member 6 |
| TCMBANKGE000881 | PLAT | T-PA; TPA | plasminogen activator, tissue type |
| TCMBANKGE000759 | MAP1LC3B | ATG8F; LC3B; MAP1A/1BLC3; MAP1LC3B-a | microtubule associated protein 1 light chain 3 beta |
| TCMBANKGE000973 | EGF | HOMG4; URG | epidermal growth factor |
| TCMBANKGE001180 | SMAD3 | HSPC193; HsT17436; JV15-2; LDS1C; LDS3; MADH3 | SMAD family member 3 |
| TCMBANKGE000944 | NOTCH3 | CADASIL; CADASIL1; CASIL; IMF2; LMNS | notch receptor 3 |
| TCMBANKGE014280 | JAG1 | AGS; AGS1; AHD; AWS; CD339; DCHE; HJ1; JAGL1 | jagged canonical Notch ligand 1 |
| TCMBANKGE010781 | BRCA2 | BRCC2; BROVCA2; FACD; FAD; FAD1; FANCD; FANCD1; GLM3; PNCA2; XRCC11 | BRCA2 DNA repair associated |
| TCMBANKGE000970 | FASN | FAS; OA-519; SDR27X1 | fatty acid synthase |
| TCMBANKGE004151 | PRL | GHA1 | prolactin |
| TCMBANKGE003205 | WWOX | D16S432E; EIEE28; FOR; FRA16D; HHCMA56; PRO0128; SCAR12; SDR41C1; WOX1 | WW domain containing oxidoreductase |
| TCMBANKGE001089 | PARP1 | ADPRT; ADPRT 1; ADPRT1; ARTD1; PARP; PARP-1; PPOL; pADPRT-1 | poly(ADP-ribose) polymerase 1 |
| TCMBANKGE001076 | SOD2 | GClnc1; IPO-B; IPOB; MNSOD; MVCD6; Mn-SOD | superoxide dismutase 2 |
| TCMBANKGE005446 | UBL5 | HUB1 | ubiquitin like 5 |
| TCMBANKGE001103 | MDM2 | ACTFS; HDMX; LSKB; hdm2 | MDM2 proto-oncogene |
| TCMBANKGE000928 | RRM1 | R1; RIR1; RR1 | ribonucleotide reductase catalytic subunit M1 |
| TCMBANKGE008016 | KPNA2 | IPOA1; QIP2; RCH1; SRP1-alpha; SRP1alpha | karyopherin subunit alpha 2 |
| TCMBANKGE000871 | IGFBP3 | BP-53; IBP3 | insulin like growth factor binding protein 3 |
| TCMBANKGE001124 | WNT1 | BMND16; INT1; OI15 | Wnt family member 1 |
| TCMBANKGE001165 | XIAP | API3; BIRC4; IAP-3; ILP1; MIHA; XLP2; hIAP-3; hIAP3 | X-linked inhibitor of apoptosis |
| TCMBANKGE000047 | AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | AKT serine/threonine kinase 1 |
| TCMBANKGE009567 | NEURL1 | NEUR1; NEURL; RNF67; bA416N2.1; neu; neu-1 | neuralized E3 ubiquitin protein ligase 1 |
| TCMBANKGE004914 | MDM4 | BMFS6; HDMX; MDMX; MRP1 | MDM4 regulator of p53 |
| TCMBANKGE010992 | CEACAM3 | CD66D; CEA; CGM1; W264; W282 | CEA cell adhesion molecule 3 |
| TCMBANKGE000305 | PIK3CD | APDS; IMD14; P110DELTA; PI3K; p110D | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta |
| TCMBANKGE000872 | IGF1R | CD221; IGFIR; IGFR; JTK13 | insulin like growth factor 1 receptor |
| TCMBANKGE000987 | COL11A2 | DFNA13; DFNB53; FBCG2; HKE5; OSMEDA; OSMEDB; PARP; STL3 | collagen type XI alpha 2 chain |
| TCMBANKGE014240 | NF2 | ACN; BANF; SCH | neurofibromin 2 |
| TCMBANKGE000201 | ESR1 | ER; ESR; ESRA; ESTRR; Era; NR3A1 | estrogen receptor 1 |
| TCMBANKGE000032 | ARHGEF2 | GEF; GEF-H1; GEFH1; LFP40; Lfc; NEDMHM; P40 | Rho/Rac guanine nucleotide exchange factor 2 |
| TCMBANKGE011334 | CSF3 | C17orf33; CSF3OS; GCSF | colony stimulating factor 3 |
| TCMBANKGE000477 | EZH2 | ENX-1; ENX1; EZH2b; KMT6; KMT6A; WVS; WVS2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| TCMBANKGE000986 | ERBB2 | CD340; HER-2; HER-2/neu; HER2; MLN 19; NEU; NGL; TKR1 | erb-b2 receptor tyrosine kinase 2 |
| TCMBANKGE000323 | BRCA1 | BRCAI; BRCC1; BROVCA1; FANCS; IRIS; PNCA4; PPP1R53; PSCP; RNF53 | BRCA1 DNA repair associated |
| TCMBANKGE000374 | CDK6 | MCPH12; PLSTIRE | cyclin dependent kinase 6 |
| TCMBANKGE001437 | NME1 | AWD; GAAD; NB; NBS; NDKA; NDPK-A; NDPKA; NM23; NM23-H1 | NME/NM23 nucleoside diphosphate kinase 1 |
| TCMBANKGE003249 | KRT7 | CK7; K2C7; K7; SCL | keratin 7 |
| TCMBANKGE007141 | MTHFR | - | methylenetetrahydrofolate reductase |
| TCMBANKGE012961 | KDM4A | JHDM3A; JMJD2; JMJD2A; TDRD14A | lysine demethylase 4A |
| TCMBANKGE000262 | TBC1D9 | GRAMD9; MDR1 | TBC1 domain family member 9 |
| TCMBANKGE000204 | CXCL8 | GCP-1; GCP1; IL8; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1; SCYB8 | C-X-C motif chemokine ligand 8 |
| TCMBANKGE010167 | TLR6 | CD286 | toll like receptor 6 |
| TCMBANKGE000017 | MAPT | DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU | microtubule associated protein tau |
| TCMBANKGE001161 | IL2 | IL-2; TCGF; lymphokine | interleukin 2 |
| TCMBANKGE012464 | GLS | AAD20; CASGID; EIEE71; GAC; GAM; GDPAG; GLS1; KGA | glutaminase |
| TCMBANKGE002800 | TRIM28 | KAP1; PPP1R157; RNF96; TF1B; TIF1B | tripartite motif containing 28 |
| TCMBANKGE008621 | TYMS | HST422; TMS; TS | thymidylate synthetase |
| TCMBANKGE003499 | RASSF1 | 123F2; NORE2A; RASSF1A; RDA32; REH3P21 | Ras association domain family member 1 |
| TCMBANKGE003789 | HLA-DQA1 | CELIAC1; DQ-A1; DQA1; HLA-DQA | major histocompatibility complex, class II, DQ alpha 1 |
| TCMBANKGE003746 | CREBBP | CBP; KAT3A; MKHK1; RSTS; RSTS1 | CREB binding protein |
| TCMBANKGE000537 | ABCC1 | ABC29; ABCC; GS-X; MRP; MRP1 | ATP binding cassette subfamily C member 1 |
| TCMBANKGE003415 | GATA3 | HDR; HDRS | GATA binding protein 3 |
| TCMBANKGE000513 | CYP2C19 | CPCJ; CYP2C; CYPIIC17; CYPIIC19; P450C2C; P450IIC19 | cytochrome P450 family 2 subfamily C member 19 |
| TCMBANKGE001171 | SRC | ASV; SRC1; THC6; c-SRC; p60-Src | SRC proto-oncogene, non-receptor tyrosine kinase |
| TCMBANKGE013337 | GSTM2 | GST4; GSTM; GSTM2-2; GTHMUS | glutathione S-transferase mu 2 |
| TCMBANKGE009489 | ARHGEF28 | RGNEF; RIP2; p190RHOGEF | Rho guanine nucleotide exchange factor 28 |
| TCMBANKGE004266 | AR | AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM | androgen receptor |
| TCMBANKGE001664 | CEACAM7 | CGM2 | CEA cell adhesion molecule 7 |
| TCMBANKGE000751 | TRAF2 | MGC:45012; RNF117; TRAP; TRAP3 | TNF receptor associated factor 2 |
| TCMBANKGE007368 | GSTP1 | DFN7; FAEES3; GST3; GSTP; HEL-S-22; PI | glutathione S-transferase pi 1 |
| TCMBANKGE013954 | MED1 | CRSP1; CRSP200; DRIP205; DRIP230; PBP; PPARBP; PPARGBP; RB18A; TRAP220; TRIP2 | mediator complex subunit 1 |
| TCMBANKGE001106 | MTOR | FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS | mechanistic target of rapamycin kinase |
| TCMBANKGE000307 | PIK3CB | P110BETA; PI3K; PI3KBETA; PIK3C1 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta |
| TCMBANKGE008001 | MIB1 | DIP-1; DIP1; LVNC7; MIB; ZZANK2; ZZZ6 | mindbomb E3 ubiquitin protein ligase 1 |
| TCMBANKGE011442 | HMGB3 | HMG-2a; HMG-4; HMG2A; HMG4 | high mobility group box 3 |
| TCMBANKGE008172 | MAOA | BRNRS; MAO-A | monoamine oxidase A |
| TCMBANKGE000227 | BMI1 | FLVI2/BMI1; PCGF4; RNF51; flvi-2/bmi-1 | BMI1 proto-oncogene, polycomb ring finger |
| TCMBANKGE000980 | SOX2 | ANOP3; MCOPS3 | SRY-box transcription factor 2 |
| TCMBANKGE009504 | SND1 | TDRD11; Tudor-SN; p100 | staphylococcal nuclease and tudor domain containing 1 |
| TCMBANKGE000758 | HSF1 | HSTF1 | heat shock transcription factor 1 |
| TCMBANKGE006210 | CHST15 | BRAG; GALNAC4S-6ST | carbohydrate sulfotransferase 15 |
| TCMBANKGE002282 | FOXF2 | FKHL6; FREAC-2; FREAC2 | forkhead box F2 |
| TCMBANKGE001100 | MIR155 | MIRN155; miRNA155; mir-155 | microRNA 155 |
| TCMBANKGE000327 | SYK | p72-Syk | spleen associated tyrosine kinase |
| TCMBANKGE002762 | OCA2 | BEY; BEY1; BEY2; BOCA; D15S12; EYCL; EYCL2; EYCL3; HCL3; P; PED; SHEP1 | OCA2 melanosomal transmembrane protein |
| TCMBANKGE003250 | CD276 | 4Ig-B7-H3; B7-H3; B7H3; B7RP-2 | CD276 molecule |
| TCMBANKGE002709 | RHBDD2 | NPD007; RHBDL7 | rhomboid domain containing 2 |
| TCMBANKGE007389 | DPYD | DHP; DHPDHASE; DPD | dihydropyrimidine dehydrogenase |
| TCMBANKGE000835 | APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | amyloid beta precursor protein |
| TCMBANKGE001170 | CDK4 | CMM3; PSK-J3 | cyclin dependent kinase 4 |
| TCMBANKGE005423 | RIPK2 | CARD3; CARDIAK; CCK; GIG30; RICK; RIP2 | receptor interacting serine/threonine kinase 2 |
| TCMBANKGE001160 | CD274 | B7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1; hPD-L1 | CD274 molecule |
| TCMBANKGE010090 | NFATC2 | NFAT1; NFATP | nuclear factor of activated T cells 2 |
| TCMBANKGE001021 | MUC1 | ADMCKD; ADMCKD1; CA 15-3; CD227; EMA; H23AG; KL-6; MAM6; MCD; MCKD; MCKD1; MUC-1; MUC-1/SEC; MUC-1/X; MUC1/ZD; PEM; PEMT; PUM | mucin 1, cell surface associated |
| TCMBANKGE000136 | MKI67 | KIA; MIB-; MIB-1; PPP1R105 | marker of proliferation Ki-67 |
| TCMBANKGE009742 | HLA-DRB1 | DRB1; HLA-DR1B; HLA-DRB; SS1 | major histocompatibility complex, class II, DR beta 1 |
| TCMBANKGE000293 | TPT1 | HRF; TCTP; p02; p23 | tumor protein, translationally-controlled 1 |
| TCMBANKGE000130 | TOP2A | TOP2; TP2A | DNA topoisomerase II alpha |
| TCMBANKGE000290 | NQO1 | DHQU; DIA4; DTD; NMOR1; NMORI; QR1 | NAD(P)H quinone dehydrogenase 1 |
| TCMBANKGE008444 | SLC2A4RG | GEF; HDBP-1; HDBP1; Si-1-2; Si-1-2-19 | SLC2A4 regulator |
| TCMBANKGE010277 | CYP2D6 | CPD6; CYP2D; CYP2D7AP; CYP2D7BP; CYP2D7P2; CYP2D8P2; CYP2DL1; CYPIID6; P450-DB1; P450C2D; P450DB1 | cytochrome P450 family 2 subfamily D member 6 |
| TCMBANKGE013295 | USP8 | HumORF8; PITA4; SPG59; UBPY | ubiquitin specific peptidase 8 |
| TCMBANKGE000264 | ABCB1 | ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1 | ATP binding cassette subfamily B member 1 |
| TCMBANKGE000885 | SPP1 | BNSP; BSPI; ETA-1; OPN | secreted phosphoprotein 1 |
| TCMBANKGE002608 | PSG2 | CEA; PSBG2; PSG1 | pregnancy specific beta-1-glycoprotein 2 |
| TCMBANKGE001096 | TLR4 | ARMD10; CD284; TLR-4; TOLL | toll like receptor 4 |
| TCMBANKGE012286 | WIF1 | WIF-1 | WNT inhibitory factor 1 |
| TCMBANKGE001102 | MIR21 | MIRN21; hsa-mir-21; miR-21; miRNA21 | microRNA 21 |
| TCMBANKGE005995 | PALB2 | FANCN; PNCA3 | partner and localizer of BRCA2 |
| TCMBANKGE000931 | CYP17A1 | CPT7; CYP17; P450C17; S17AH | cytochrome P450 family 17 subfamily A member 1 |
| TCMBANKGE003588 | RRM2B | MTDPS8A; MTDPS8B; P53R2 | ribonucleotide reductase regulatory TP53 inducible subunit M2B |
| TCMBANKGE006425 | SLC26A4 | DFNB4; EVA; PDS; TDH2B | solute carrier family 26 member 4 |
| TCMBANKGE013902 | HDAC9 | HD7; HD7b; HD9; HDAC; HDAC7; HDAC7B; HDAC9B; HDAC9FL; HDRP; MITR | histone deacetylase 9 |
| TCMBANKGE001172 | HSP90AA1 | EL52; HEL-S-65p; HSP86; HSP89A; HSP90A; HSP90N; HSPC1; HSPCA; HSPCAL1; HSPCAL4; HSPN; Hsp103; Hsp89; Hsp90; LAP-2; LAP2 | heat shock protein 90 alpha family class A member 1 |
| TCMBANKGE003572 | MELK | HPK38 | maternal embryonic leucine zipper kinase |
| TCMBANKGE000306 | PIK3CG | PI3CG; PI3K; PI3Kgamma; PIK3; p110gamma; p120-PI3K | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma |
| TCMBANKGE000979 | KDR | CD309; FLK1; VEGFR; VEGFR2 | kinase insert domain receptor |
| TCMBANKGE009774 | MSH3 | DUP; FAP4; MRP1 | mutS homolog 3 |
| TCMBANKGE000474 | NCOA1 | F-SRC-1; KAT13A; RIP160; SRC1; bHLHe42; bHLHe74 | nuclear receptor coactivator 1 |
| TCMBANKGE000414 | CYP19A1 | ARO; ARO1; CPV1; CYAR; CYP19; CYPXIX; P-450AROM | cytochrome P450 family 19 subfamily A member 1 |
| TCMBANKGE011990 | CEACAM5 | CD66e; CEA | CEA cell adhesion molecule 5 |
| TCMBANKGE007692 | GSTM1 | GST1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GTH4; GTM1; H-B; MU; MU-1 | glutathione S-transferase mu 1 |
| TCMBANKGE000771 | TWIST1 | ACS3; BPES2; BPES3; CRS; CRS1; CSO; SCS; SWCOS; TWIST; bHLHa38 | twist family bHLH transcription factor 1 |
| TCMBANKGE005460 | XPR1 | IBGC6; SLC53A1; SYG1; X3 | xenotropic and polytropic retrovirus receptor 1 |
| TCMBANKGE003670 | ABCB6 | ABC; LAN; MTABC3; PRP; umat | ATP binding cassette subfamily B member 6 (Langereis blood group) |
| TCMBANKGE014777 | NEU1 | NANH; NEU; SIAL1 | neuraminidase 1 |
| TCMBANKGE009139 | TP73 | P73 | tumor protein p73 |
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Dai SX Lab