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疾病ID:TCMBANKDI015030


疾病名:DOWN SYNDROME CRITICAL REGION


MeSH_Name:Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases


HPO_Name:-


UMLS_Name:Disease or Syndrome


DO_Name:genetic disease


疾病类型:disease


DisGeNET_Link:C1860787


MeSH_Link:C16; C10


HPO_Link:-


UMLS_Link:T047


DO_Link:DOID:630


HERB_ID:HBDIS017797


   疾病对应的植物
ID 拉丁名 药名 药用植物名 功能与主治 来源 药用部位 使用民族

   疾病对应的化合物
化合物ID 化合物名 别名 分子式 分子质量 Smiles

   疾病对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE003874 CXCR6 BONZO; CD186; STRL33; TYMSTR C-X-C motif chemokine receptor 6
TCMBANKGE008124 ADRA2B ADRA2L1; ADRA2RL1; ADRARL1; ALPHA2BAR; FAME2; alpha-2BAR adrenoceptor alpha 2B
TCMBANKGE004055 SSTR4 SS-4-R; SS4-R; SS4R somatostatin receptor 4
TCMBANKGE004990 RCAN1 ADAPT78; CSP1; DSC1; DSCR1; MCIP1; RCN1 regulator of calcineurin 1
TCMBANKGE014106 LPAR2 EDG-4; EDG4; LPA-2; LPA2 lysophosphatidic acid receptor 2
TCMBANKGE000836 BACE1 ASP2; BACE; HSPC104 beta-secretase 1
TCMBANKGE005680 CHAF1B CAF-1; CAF-IP60; CAF1; CAF1A; CAF1P60; MPHOSPH7; MPP7 chromatin assembly factor 1 subunit B
TCMBANKGE002837 BRWD1 C21orf107; DCAF19; N143; WDR9; WRD9 bromodomain and WD repeat domain containing 1
TCMBANKGE004021 FMR1 FMRP; FRAXA; POF; POF1 FMRP translational regulator 1
TCMBANKGE012642 COL18A1 GLCC; KNO; KNO1; KS collagen type XVIII alpha 1 chain
TCMBANKGE013860 EDNRA ET-A; ETA; ETA-R; ETAR; ETRA; MFDA; hET-AR endothelin receptor type A
TCMBANKGE000087 TNFRSF10C CD263; DCR1; DCR1-TNFR; LIT; TRAIL-R3; TRAILR3; TRID TNF receptor superfamily member 10c
TCMBANKGE000497 ETS2 ETS2IT1 ETS proto-oncogene 2, transcription factor
TCMBANKGE011173 FAM3B 2-21; C21orf11; C21orf76; ORF9; PANDER; PRED44 FAM3 metabolism regulating signaling molecule B
TCMBANKGE008178 SULT1E1 EST; EST-1; ST1E1; STE sulfotransferase family 1E member 1
TCMBANKGE013679 DICER1 DCR1; Dicer; Dicer1e; GLOW; HERNA; K12H4.8-LIKE; MNG1; RMSE2 dicer 1, ribonuclease III
TCMBANKGE009726 ERG erg-3; p55 ETS transcription factor ERG
TCMBANKGE000017 MAPT DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU microtubule associated protein tau
TCMBANKGE008385 MAP3K8 AURA2; COT; EST; ESTF; MEKK8; TPL2; Tpl-2; c-COT mitogen-activated protein kinase kinase kinase 8
TCMBANKGE010943 BRS3 BB3; BB3R; BBR3 bombesin receptor subtype 3
TCMBANKGE011010 RUNX1 AML1; AML1-EVI-1; AMLCR1; CBF2alpha; CBFA2; EVI-1; PEBP2aB; PEBP2alpha RUNX family transcription factor 1
TCMBANKGE014423 ADRA1A ADRA1C; ADRA1L1; ALPHA1AAR adrenoceptor alpha 1A
TCMBANKGE010372 BACE2 AEPLC; ALP56; ASP1; ASP21; BAE2; CDA13; CEAP1; DRAP beta-secretase 2
TCMBANKGE002078 PIGP DCRC; DCRC-S; DSCR5; DSRC; EIEE55; PIG-P phosphatidylinositol glycan anchor biosynthesis class P
TCMBANKGE010386 HLCS HCS holocarboxylase synthetase
TCMBANKGE011218 KISS1 HH13; KiSS-1 KiSS-1 metastasis suppressor
TCMBANKGE000835 APP AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 amyloid beta precursor protein
TCMBANKGE000407 DYRK1A DYRK; DYRK1; HP86; MNB; MNBH; MRD7 dual specificity tyrosine phosphorylation regulated kinase 1A
TCMBANKGE000072 CXCL12 IRH; PBSF; SCYB12; SDF1; TLSF; TPAR1 C-X-C motif chemokine ligand 12
TCMBANKGE000747 GAPDH G3PD; GAPD; HEL-S-162eP glyceraldehyde-3-phosphate dehydrogenase
TCMBANKGE014408 CIT CITK; CRIK; MCPH17; STK21 citron rho-interacting serine/threonine kinase
TCMBANKGE000025 TNFRSF10D CD264; DCR2; TRAIL-R4; TRAILR4; TRUNDD TNF receptor superfamily member 10d
TCMBANKGE004320 RIPPLY3 DSCR6 ripply transcriptional repressor 3
TCMBANKGE005781 CBR1 CBR; SDR21C1; hCBR1 carbonyl reductase 1
TCMBANKGE000333 CCR6 BN-1; C-C CKR-6; CC-CKR-6; CCR-6; CD196; CKR-L3; CKRL3; CMKBR6; DCR2; DRY6; GPR29; GPRCY4; STRL22 C-C motif chemokine receptor 6
TCMBANKGE014558 TTC3 DCRR1; RNF105; TPRDIII tetratricopeptide repeat domain 3
TCMBANKGE008723 PDE10A ADSD2; HSPDE10A; IOLOD; LINC00473; PDE10A19 phosphodiesterase 10A
TCMBANKGE000868 NFATC1 NF-ATC; NF-ATc1.2; NFAT2; NFATc nuclear factor of activated T cells 1