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疾病ID:TCMBANKDI019385
疾病名:Fuchs Endothelial Dystrophy
MeSH_Name:Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
HPO_Name:-
UMLS_Name:Disease or Syndrome
DO_Name:disease of anatomical entity
疾病类型:disease
DisGeNET_Link:C0016781
MeSH_Link:C16; C11
HPO_Link:-
UMLS_Link:T047
DO_Link:DOID:7
HERB_ID:-
疾病对应的植物
| ID | 拉丁名 | 药名 | 药用植物名 | 功能与主治 | 来源 | 药用部位 | 使用民族 |
|---|
疾病对应的化合物
| 化合物ID | 化合物名 | 别名 | 分子式 | 分子质量 | Smiles |
|---|
疾病对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE008264 | PBK | CT84; HEL164; Nori-3; SPK; TOPK | PDZ binding kinase |
| TCMBANKGE006357 | FEN1 | FEN-1; MF1; RAD2 | flap structure-specific endonuclease 1 |
| TCMBANKGE001577 | DAPK2 | DRP-1; DRP1 | death associated protein kinase 2 |
| TCMBANKGE000567 | CDKN2A | ARF; CDK4I; CDKN2; CMM2; INK4; INK4A; MLM; MTS-1; MTS1; P14; P14ARF; P16; P16-INK4A; P16INK4; P16INK4A; P19; P19ARF; TP16 | cyclin dependent kinase inhibitor 2A |
| TCMBANKGE001089 | PARP1 | ADPRT; ADPRT 1; ADPRT1; ARTD1; PARP; PARP-1; PPOL; pADPRT-1 | poly(ADP-ribose) polymerase 1 |
| TCMBANKGE001009 | CRMP1 | CRMP-1; DPYSL1; DRP-1; DRP1; ULIP-3 | collapsin response mediator protein 1 |
| TCMBANKGE013962 | SLC4A11 | BTR1; CDPD1; CHED; CHED2; NABC1; dJ794I6.2 | solute carrier family 4 member 11 |
| TCMBANKGE001146 | SNAI1 | SLUGH2; SNA; SNAH; SNAIL; SNAIL1; dJ710H13.1 | snail family transcriptional repressor 1 |
| TCMBANKGE000294 | CDKN1A | CAP20; CDKN1; CIP1; MDA-6; P21; SDI1; WAF1; p21CIP1 | cyclin dependent kinase inhibitor 1A |
| TCMBANKGE013036 | LIG3 | LIG2; LIG3alpha | DNA ligase 3 |
| TCMBANKGE001147 | CDH1 | Arc-1; BCDS1; CD324; CDHE; ECAD; LCAM; UVO | cadherin 1 |
| TCMBANKGE012406 | FGF7 | HBGF-7; KGF | fibroblast growth factor 7 |
| TCMBANKGE000305 | PIK3CD | APDS; IMD14; P110DELTA; PI3K; p110D | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta |
| TCMBANKGE000042 | GPR35 | - | G protein-coupled receptor 35 |
| TCMBANKGE001039 | PINK1 | BRPK; PARK6 | PTEN induced kinase 1 |
| TCMBANKGE001048 | TGM2 | TG(C); TGC | transglutaminase 2 |
| TCMBANKGE003055 | CCL21 | 6Ckine; CKb9; ECL; SCYA21; SLC; TCA4 | C-C motif chemokine ligand 21 |
| TCMBANKGE000196 | FAS | ALPS1A; APO-1; APT1; CD95; FAS1; FASTM; TNFRSF6 | Fas cell surface death receptor |
| TCMBANKGE002201 | ATP1B1 | ATP1B | ATPase Na+/K+ transporting subunit beta 1 |
| TCMBANKGE001142 | CHDH | - | choline dehydrogenase |
| TCMBANKGE000321 | NOX4 | KOX; KOX-1; RENOX | NADPH oxidase 4 |
| TCMBANKGE012010 | LAMC1 | LAMB2 | laminin subunit gamma 1 |
| TCMBANKGE002022 | XRCC1 | RCC; SCAR26 | X-ray repair cross complementing 1 |
| TCMBANKGE006773 | AGBL1 | CCP4; FECD8 | ATP/GTP binding protein like 1 |
| TCMBANKGE003249 | KRT7 | CK7; K2C7; K7; SCL | keratin 7 |
| TCMBANKGE012604 | MBNL1 | EXP; MBNL | muscleblind like splicing regulator 1 |
| TCMBANKGE000154 | CCR2 | CC-CKR-2; CCR-2; CCR2A; CCR2B; CD192; CKR2; CKR2A; CKR2B; CMKBR2; MCP-1-R | C-C motif chemokine receptor 2 |
| TCMBANKGE013480 | NEIL1 | FPG1; NEI1; hFPG1 | nei like DNA glycosylase 1 |
| TCMBANKGE000271 | APOE | AD2; APO-E; ApoE4; LDLCQ5; LPG | apolipoprotein E |
| TCMBANKGE013582 | SOD3 | EC-SOD | superoxide dismutase 3 |
| TCMBANKGE013679 | DICER1 | DCR1; Dicer; Dicer1e; GLOW; HERNA; K12H4.8-LIKE; MNG1; RMSE2 | dicer 1, ribonuclease III |
| TCMBANKGE000127 | MFN2 | CMT2A; CMT2A2; CMT2A2A; CMT2A2B; CPRP1; HMSN6A; HSG; MARF | mitofusin 2 |
| TCMBANKGE001126 | NFE2L2 | HEBP1; IMDDHH; NRF2; Nrf-2 | nuclear factor, erythroid 2 like 2 |
| TCMBANKGE004061 | KIF13A | RBKIN; bA500C11.2 | kinesin family member 13A |
| TCMBANKGE007319 | MBNL2 | MBLL; MBLL39; PRO2032 | muscleblind like splicing regulator 2 |
| TCMBANKGE000792 | FASLG | ALPS1B; APT1LG1; APTL; CD178; CD95-L; CD95L; FASL; TNFSF6; TNLG1A | Fas ligand |
| TCMBANKGE000563 | CLU | AAG4; APO-J; APOJ; CLI; CLU1; CLU2; KUB1; NA1/NA2; SGP-2; SGP2; SP-40; TRPM-2; TRPM2 | clusterin |
| TCMBANKGE002410 | PITX2 | ARP1; ASGD4; Brx1; IDG2; IGDS; IGDS2; IHG2; IRID2; Otlx2; PTX2; RGS; RIEG; RIEG1; RS | paired like homeodomain 2 |
| TCMBANKGE004723 | AKAP13 | AKAP-13; AKAP-Lbc; ARHGEF13; BRX; HA-3; Ht31; LBC; PRKA13; PROTO-LB; PROTO-LBC; c-lbc; p47 | A-kinase anchoring protein 13 |
| TCMBANKGE001145 | CDH2 | CD325; CDHN; CDw325; NCAD | cadherin 2 |
| TCMBANKGE014548 | FGF9 | FGF-9; GAF; HBFG-9; HBGF-9; SYNS3 | fibroblast growth factor 9 |
| TCMBANKGE000307 | PIK3CB | P110BETA; PI3K; PI3KBETA; PIK3C1 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta |
| TCMBANKGE005283 | CUL3 | CUL-3; PHA2E | cullin 3 |
| TCMBANKGE014962 | COX8A | COX; COX8; COX8-2; COX8L; VIII; VIII-L | cytochrome c oxidase subunit 8A |
| TCMBANKGE006691 | FGFR3 | ACH; CD333; CEK2; HSFGFR3EX; JTK4 | fibroblast growth factor receptor 3 |
| TCMBANKGE000823 | GABPA | E4TF1-60; E4TF1A; NFT2; NRF2; NRF2A; RCH04A07 | GA binding protein transcription factor subunit alpha |
| TCMBANKGE000388 | ZEB1 | AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3; TCF8; ZFHEP; ZFHX1A | zinc finger E-box binding homeobox 1 |
| TCMBANKGE012260 | TF | HEL-S-71p; PRO1557; PRO2086; TFQTL1 | transferrin |
| TCMBANKGE000242 | SAA1 | PIG4; SAA; SAA2; TP53I4 | serum amyloid A1 |
| TCMBANKGE000239 | UTRN | DMDL; DRP; DRP1 | utrophin |
| TCMBANKGE000109 | ACTB | BRWS1; PS1TP5BP1 | actin beta |
| TCMBANKGE002559 | CFH | AHUS1; AMBP1; ARMD4; ARMS1; CFHL3; FH; FHL1; HF; HF1; HF2; HUS | complement factor H |
| TCMBANKGE010270 | APEX1 | APE; APE1; APEN; APEX; APX; HAP1; REF1 | apurinic/apyrimidinic endodeoxyribonuclease 1 |
| TCMBANKGE008164 | TGFBI | BIGH3; CDB1; CDG2; CDGG1; CSD; CSD1; CSD2; CSD3; EBMD; LCD1 | transforming growth factor beta induced |
| TCMBANKGE000290 | NQO1 | DHQU; DIA4; DTD; NMOR1; NMORI; QR1 | NAD(P)H quinone dehydrogenase 1 |
| TCMBANKGE000240 | IL17A | CTLA-8; CTLA8; IL-17; IL-17A; IL17 | interleukin 17A |
| TCMBANKGE000884 | FN1 | CIG; ED-B; FINC; FN; FNZ; GFND; GFND2; LETS; MSF; SMDCF | fibronectin 1 |
| TCMBANKGE002913 | ETS1 | ETS-1; EWSR2; c-ets-1; p54 | ETS proto-oncogene 1, transcription factor |
| TCMBANKGE000788 | SELE | CD62E; ELAM; ELAM1; ESEL; LECAM2 | selectin E |
| TCMBANKGE000180 | TCF4 | CDG2T; E2-2; FECD3; ITF-2; ITF2; PTHS; SEF-2; SEF2; SEF2-1; SEF2-1A; SEF2-1B; SEF2-1D; TCF-4; bHLHb19 | transcription factor 4 |
| TCMBANKGE010359 | DMPK | DM; DM1; DM1PK; DMK; MDPK; MT-PK | DM1 protein kinase |
| TCMBANKGE001072 | DNM1L | DLP1; DRP1; DVLP; DYMPLE; EMPF; EMPF1; HDYNIV; OPA5 | dynamin 1 like |
| TCMBANKGE012020 | KANK4 | ANKRD38; dJ1078M7.1 | KN motif and ankyrin repeat domains 4 |
| TCMBANKGE010679 | DENR | DRP; DRP1; SMAP-3 | density regulated re-initiation and release factor |
| TCMBANKGE000382 | PARK7 | DJ-1; DJ1; GATD2; HEL-S-67p | Parkinsonism associated deglycase |
| TCMBANKGE004834 | HLA-DRA | HLA-DRA1 | major histocompatibility complex, class II, DR alpha |
| TCMBANKGE000306 | PIK3CG | PI3CG; PI3K; PI3Kgamma; PIK3; p110gamma; p120-PI3K | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma |
| TCMBANKGE000236 | BDNF | ANON2; BULN2 | brain derived neurotrophic factor |
| TCMBANKGE005266 | ZNF469 | BCS; BCS1; Zfp469 | zinc finger protein 469 |
| TCMBANKGE001795 | PTPRG | HPTPG; PTPG; R-PTP-GAMMA; RPTPG | protein tyrosine phosphatase receptor type G |
| TCMBANKGE000946 | RAD51 | BRCC5; FANCR; HRAD51; HsRad51; HsT16930; MRMV2; RAD51A; RECA | RAD51 recombinase |
| TCMBANKGE011544 | IGHG1 | - | immunoglobulin heavy constant gamma 1 (G1m marker) |
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Dai SX Lab